Chronobiology International最新文献_第3页

Cognitive impairment induced by circadian rhythm disorders involves hippocampal brain-derived neurotrophic factor reduction and amyloid-β deposition. 昼夜节律紊乱引起的认知障碍涉及海马脑源性神经营养因子减少和淀粉样蛋白-β沉积。

IF 2.2 4区医学

Chronobiology International Pub Date : 2024-10-01 Epub Date: 2024-09-23 DOI: 10.1080/07420528.2024.2406545

Yue-Jia Yan, Chang-Quan Huang

{"title":"Cognitive impairment induced by circadian rhythm disorders involves hippocampal brain-derived neurotrophic factor reduction and amyloid-β deposition.","authors":"Yue-Jia Yan, Chang-Quan Huang","doi":"10.1080/07420528.2024.2406545","DOIUrl":"10.1080/07420528.2024.2406545","url":null,"abstract":"Circadian rhythm disruptions have been implicated in numerous health issues, including cognitive decline and the exacerbation of neurodegenerative diseases, like Alzheimer disease (AD). Brain-derived neurotrophic factor (BDNF), vital for neuronal plasticity and cognitive function, is regulated by the circadian clock and exerts protective effects against AD. Thus, we investigated the impact of circadian rhythm disorders (CRDs) on cognitive impairment and explored the underlying neurobiological mechanisms by assessing BDNF and amyloid-β (Aβ) levels. We divided male C57BL/6 mice into three groups (n = 30): a control group (normal 12/12 hour light-dark cycle) and two CRD model groups (3/3 and 22/22 hour cycles, respectively). After 12 weeks, we assessed cognitive functions using the Morris water maze. Following behavioral tests, hippocampal levels of BDNF and Aβ were quantified using enzyme-linked immunosorbent assays. CRDs significantly impaired learning and memory, as evidenced by longer times to reach and find the platform in the CRD groups (p < 0.01). Furthermore, BDNF levels were notably decreased and Aβ levels increased in the CRD groups compared with the control group (p < 0.01). Thus, CRDs elicit cognitive impairment by reducing BDNF levels and increasing Aβ deposition in the hippocampus.","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"1299-1306"},"PeriodicalIF":2.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142281269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Validation of the English-language version of the Morningness-Eveningness-Stability-Scale-improved (MESSi), and comparison with a measure of sleep inertia. 英语版晨起-均匀性-稳定性-量表改进版（MESSi）的验证，以及与睡眠惰性测量方法的比较。

IF 2.2 4区医学

Chronobiology International Pub Date : 2024-10-01 Epub Date: 2024-10-11 DOI: 10.1080/07420528.2024.2414047

Richard Carciofo

{"title":"Validation of the English-language version of the Morningness-Eveningness-Stability-Scale-improved (MESSi), and comparison with a measure of sleep inertia.","authors":"Richard Carciofo","doi":"10.1080/07420528.2024.2414047","DOIUrl":"10.1080/07420528.2024.2414047","url":null,"abstract":"The Morningness-Eveningness-Stability-Scale-improved (MESSi) assesses three components of circadian functioning: Morning Affect (time to fully awaken), Eveningness (orientation/preference for evening activity), and Distinctness (amplitude of diurnal variations in functioning). Following the original German version, translations of the MESSi (including Spanish, Turkish, and Chinese) have been validated, but validity evidence for the English-language version has been lacking. The current study tested the factor structure, internal consistency, and predicted correlations of the English-language MESSi. A sample of 600 adults from an online recruitment platform (aged 18-78, mean = 41.31, SD = 13.149) completed an online survey including the MESSi, reduced Morningness-Eveningness Questionnaire (rMEQ), Sleep Inertia Questionnaire (SIQ), and measures of personality and depressive symptoms. Exploratory factor analysis exactly reproduced the three-component structure of Morning Affect (MA), Eveningness, and Distinctness, with all items loading strongly on their respective component. Confirmatory factor analysis of this structure showed acceptable fit. The three subscales showed good internal consistency and replicated previously reported correlations with depressive symptoms, sleep inertia, sleep quality, and personality. Further factor analysis combining the items of the MESSi, rMEQ, and SIQ replicated a previously found seven-factor structure: Cognitive, Emotional, and Physiological sleep inertia (SI), Responses to SI (including one MA item); Duration of SI (one SIQ item, 3/5 MA items); Morningness-Eveningness (MESSi Eveningness items, plus 3/5 rMEQ items); Distinctness (5/5 MESSi items). In conclusion, the English-language MESSi shows sound psychometric properties, but Morning Affect may be more suitably characterised as a measure of sleep inertia duration, rather than morningness preference.","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"1328-1339"},"PeriodicalIF":2.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142399581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chronotype, sleep quality, impulsivity and aggression in patients with borderline personality disorder and healthy controls. 边缘型人格障碍患者和健康对照组的时间型、睡眠质量、冲动性和攻击性。

IF 2.2 4区医学

Chronobiology International Pub Date : 2024-10-01 DOI: 10.1080/07420528.2024.2410239

Yasin Taşdelen, Ali İnaltekin

{"title":"Chronotype, sleep quality, impulsivity and aggression in patients with borderline personality disorder and healthy controls.","authors":"Yasin Taşdelen, Ali İnaltekin","doi":"10.1080/07420528.2024.2410239","DOIUrl":"10.1080/07420528.2024.2410239","url":null,"abstract":"Impulsivity, aggression, and suicide are the major clinical symptoms of borderline personality disorder (BPD). Although previous studies indicated poor sleep quality and its relationship with clinical symptoms in patients with BPD, chronotype, an important sleep parameter, was not investigated in these patients. This study aimed to analyze chronotype and its relationship with clinical symptoms in patients with BPD. Participants in this study consisted of 68 BPD patients and 65 healthy controls. Subjective sleep characteristics, impulsivity, aggression, suicide probability, and chronotype were assessed using the Pittsburgh Sleep Quality Index (PSQI), Barratt Impulsivity Scale, Buss-Perry Aggression Scale (BPAQ), Suicide Probability Scale, and Morningness - Eveningness Questionnaire, respectively. PSQI total and subscale scores subjective sleep quality, sleep latency, sleep duration, habitual sleep efficiency, sleep disturbances, and daytime drowsiness were significantly higher in the BPD group (p < 0.001). There was a positive correlation between the PSQI total score and the BPAQ total score (r = 0.268, p = 0.027). The rate of evening type was significantly higher in the control group (p = 0.004). Suicide attempts and the subscale of suicide probability hopelessness, suicidal ideation, and negative self-evaluation scores were significantly higher in evening type BPD patients. (p = 0.017, p = 0.009, p = 0.001, p = 0.047). Sleep quality is associated with aggression, and the eveningness chronotype is associated with suicide. It may be useful to focus on sleep problems in treating BPD patients.","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"1307-1312"},"PeriodicalIF":2.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142342745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The relationship between chronotype characteristics and fear of missing out, phubbing, sleep quality and social jetlag in medical students. 医学生的时间型特征与害怕错过、嗜睡、睡眠质量和社交时差之间的关系。

IF 2.2 4区医学

Chronobiology International Pub Date : 2024-10-01 Epub Date: 2024-10-21 DOI: 10.1080/07420528.2024.2416986

Cansu Mercan Işik, Masum Öztürk

{"title":"The relationship between chronotype characteristics and fear of missing out, phubbing, sleep quality and social jetlag in medical students.","authors":"Cansu Mercan Işik, Masum Öztürk","doi":"10.1080/07420528.2024.2416986","DOIUrl":"10.1080/07420528.2024.2416986","url":null,"abstract":"Chronotype is the temporal behavior of an organism. Social jetlag, fear of missing out (FoMO), and phubbing have received increasing attention recently and are closely related to sleep quality. This study aimed to explore the relationship between chronotype and these factors and their effects on sleep quality among medical students. The FoMO scale, phubbing behavior assessment scale, morning-evening questionnaire, Pittsburgh sleep quality index, social jetlag questionnaire, and online sociodemographic data form were filled out by 537 students participating in the study. The average age of participants was 21.34 ± 1.38 years; 43.2% were male, and 56.8% were female. The majority (66.7%) had an intermediate chronotype, 20.9% an evening type, and 12.5% a morning type. Evening chronotypes exhibited the highest levels of social jetlag, daily internet/phone use, and the poorest sleep quality and daily functioning. Women reported significantly higher levels of FoMO (p < 0.001), phubbing (p = 0.020), and daytime dysfunction (p = 0.005). Multiple regression analysis showed poor sleep quality was associated with high FoMO, high phubbing, high levels of social jetlag, and evening chronotype. Additionally, daytime dysfunction was associated with female gender, poor sleep quality, high FoMO, and high levels of phubbing (p < 0.001, F = 16.128, R2 = 0.221). These results suggest that individuals with an evening type may be susceptible to social interaction, social media use, and sleep patterns, which may negatively affect sleep quality. It has also been determined that females may be at greater risk for FoMO and phubbing. Evaluation of individuals' chronotypes will be an essential step in treating behavioral addictions such as social media, screen, and smartphone addiction.","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"1340-1350"},"PeriodicalIF":2.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142459449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Circadian rhythm in hypertension: An updated bibliometrics analysis and knowledge mapping from 1990 to 2022 高血压的昼夜节律：1990年至2022年最新文献计量学分析和知识图谱

IF 2.8 4区医学

Chronobiology International Pub Date : 2024-09-16 DOI: 10.1080/07420528.2024.2403434

Heng Bai, Si-Yang Liu, Jie Tian, Yu Li

引用次数: 0

The relationship between morningness-eveningness and naturalness bias. 晨昏度与自然度偏差之间的关系。

IF 2.2 4区医学

Chronobiology International Pub Date : 2024-09-01 Epub Date: 2024-08-29 DOI: 10.1080/07420528.2024.2397390

Heng Li

{"title":"The relationship between morningness-eveningness and naturalness bias.","authors":"Heng Li","doi":"10.1080/07420528.2024.2397390","DOIUrl":"10.1080/07420528.2024.2397390","url":null,"abstract":"The naturalness bias in which people perceive natural items to be safer, healthier, and better than synthetic alternatives has been found to be associated with numerous individual difference variables (e.g. connectedness to nature and religiosity). However, no research has examined the role of morningness-eveningness in influencing preferences for naturalness. Here, we propose that evening individuals may exhibit a weaker preference for naturalness compared to morning individuals due to their greater exposure to artificial lighting, technology, and stimuli. To systematically test our theoretical perspective, we conducted three complementary and high-powered studies. In an online survey (Study 1), student participants with a stronger evening orientation displayed a diminished preference for natural drugs compared to those with a morning orientation. Using a sample of community adults, Study 2 replicated the findings of Study 1 in a real-world, behavioral context. Study 3 examined the relationship between morningness-eveningness and preference for naturalness within the domain of beverages. The results revealed that individuals with an evening-orientation had decreased odds of selecting natural water without minerals. Taken together, the findings suggest that an individual's diurnal preference toward eveningness may have implications for their bias toward and perception of naturalness across various domains.","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"1255-1264"},"PeriodicalIF":2.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142104876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Improvement of social frailty is associated with stability of nonparametric characteristics of the rest-activity rhythm and improvement of the usual walking ability in the elderly. 社会脆弱性的改善与老年人休息-活动节奏非参数特征的稳定和通常行走能力的提高有关。

IF 2.2 4区医学

Chronobiology International Pub Date : 2024-09-01 Epub Date: 2024-08-20 DOI: 10.1080/07420528.2024.2393877

Yu Kume, Ayuto Kodama, Sayaka Arai, Makiko Nagaoka, Akiko Sato, Akira Saito, Hidetaka Ota, Hideaki Ando

{"title":"Improvement of social frailty is associated with stability of nonparametric characteristics of the rest-activity rhythm and improvement of the usual walking ability in the elderly.","authors":"Yu Kume, Ayuto Kodama, Sayaka Arai, Makiko Nagaoka, Akiko Sato, Akira Saito, Hidetaka Ota, Hideaki Ando","doi":"10.1080/07420528.2024.2393877","DOIUrl":"10.1080/07420528.2024.2393877","url":null,"abstract":"Our study, conducted between April 2022 and January 2024, was aimed at clarifying components of the rest-activity rhythm (RAR) involved in improvement of social frailty state before or after a 3-month multi-component exercise intervention in the elderly. Participants were recruited from the general population in Akita prefecture, Japan. We administered a four-item social frailty screening questionnaire to classify the severity of social frailty in each participant before and after the 3-month intervention. The RAR parameters were measured on an Actiwatch Spectrum Plus device worn by the subjects for 7 continuous days. As the final sample, 65 participants classified into the improved/maintained group (n = 36) or the deteriorated group (n = 29) according to the change in the social frailty classification after the intervention were included in the analysis. The results of a binomial logistic regression analysis showed significantly higher values of interdaily stability (IS) and usual walking speed at the post-test after the intervention. Based on our findings, we propose that stability of the rest-activity rhythm related to synchronization with external stimuli (such as social effect and physical activity) might have clinical impact on improvement of social frailty state in elderly community-dwellers.","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"1239-1247"},"PeriodicalIF":2.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142008382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigating the interplay of chronotypes, neuropsychiatric dimensions, demographic and clinical characteristics and disability in migraine patients: A cross-sectional assessment. 调查偏头痛患者的时型、神经精神层面、人口学和临床特征与残疾之间的相互作用：横断面评估

IF 2.2 4区医学

Chronobiology International Pub Date : 2024-09-01 Epub Date: 2024-09-16 DOI: 10.1080/07420528.2024.2399126

Yasemin Ekmekyapar Fırat, Barış Yılbaş, Emine Kılıçparlar Cengiz, Süleyman Dönmezler

{"title":"Investigating the interplay of chronotypes, neuropsychiatric dimensions, demographic and clinical characteristics and disability in migraine patients: A cross-sectional assessment.","authors":"Yasemin Ekmekyapar Fırat, Barış Yılbaş, Emine Kılıçparlar Cengiz, Süleyman Dönmezler","doi":"10.1080/07420528.2024.2399126","DOIUrl":"10.1080/07420528.2024.2399126","url":null,"abstract":"The study investigated associations between chronotypes (Morning [M], Neither [N], Evening [E]), sociodemographic characteristics, body mass index (BMI), smoking habits, years with migraines, sleep quality (PSQI), anxiety (HADS-A), depression (HADS-D), migraine disability (MIDAS), headache frequency, and pain intensity (VAS) in 80 individuals with migraine. Significant age differences emerged (p < 0.001), with M-types being the oldest. BMI also varied, with M-types presenting the highest median BMI (p = 0.005). While migraine duration and headache frequency showed no significant variance, sleep quality did, with E-types reporting the poorest sleep (p = 0.030). Anxiety and depression were significantly worse in E-types (HADS-A: p = 0.002; HADS-D: p = 0.010). Differences in MIDAS levels were notable (p = 0.038); however, differences in MIDAS scores were not significant (p = 0.115). Pain intensity varied, with E-types experiencing the most severe pain (p = 0.009). Post-hoc analysis showed higher MIDAS scores in E-types compared to N-types (χ2 = 6.56, p = 0.038, ε2 = 0.0831). The findings highlight the need for thorough patient evaluations and tailored care, considering the complex interplay of factors affecting migraine severity, particularly among different chronotypes.","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"1287-1293"},"PeriodicalIF":2.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142281270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Circadian variation in coaches' decision-making in the National Football League's evening games. 全国橄榄球联盟晚间比赛中教练决策的昼夜节律变化。

IF 2.2 4区医学

Chronobiology International Pub Date : 2024-09-01 Epub Date: 2024-10-17 DOI: 10.1080/07420528.2024.2393880

Vincent Bourgon, Félix Gabriel Duval, Geneviève Forest

{"title":"Circadian variation in coaches' decision-making in the National Football League's evening games.","authors":"Vincent Bourgon, Félix Gabriel Duval, Geneviève Forest","doi":"10.1080/07420528.2024.2393880","DOIUrl":"10.1080/07420528.2024.2393880","url":null,"abstract":"The aim of this study was to explore whether National Football League (NFL) coaches show variation in their decision-making on fourth down when traveling through time zones. Data from visiting teams in games from 20 seasons (2000-2020) of the NFL were retrieved from online sources (n = 5360 games). Decision-making was measured with the percentage of offensive plays on fourth down. A factorial ANCOVA was done to verify whether travel direction had an impact on fourth downs in evening games, while controlling for the seasons. A moderation analysis was computed to verify whether the time of game moderates the relationship between longitudinal distance traveled and decisions on fourth downs. Results showed that in evening games, coaches in teams traveling westward called more offensive plays on fourth down, compared to when they traveled in any other direction. Results from the moderation analysis showed that only in evening games, further westward longitudinal degrees traveled predict more fourth downs. For the first time, this study offers insight that circadian misalignment may not only affect player performance but also influence coaching decisions in professional sports. These results beg the question whether other aspects of coaching or staff decisions show circadian variations in professional sports.","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"1248-1254"},"PeriodicalIF":2.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142459448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effects of shift work on sleep quality, diet quality, and obesity-related factors: A male population study. 轮班工作对睡眠质量、饮食质量和肥胖相关因素的影响：一项男性人口研究。

IF 2.2 4区医学

Chronobiology International Pub Date : 2024-09-01 Epub Date: 2024-08-29 DOI: 10.1080/07420528.2024.2397391

Busra Turan-Demirci, Kubra Isgin-Atici, Suleyman Nahit Sendur, Tomris Erbas, Zehra Buyuktuncer

{"title":"The effects of shift work on sleep quality, diet quality, and obesity-related factors: A male population study.","authors":"Busra Turan-Demirci, Kubra Isgin-Atici, Suleyman Nahit Sendur, Tomris Erbas, Zehra Buyuktuncer","doi":"10.1080/07420528.2024.2397391","DOIUrl":"10.1080/07420528.2024.2397391","url":null,"abstract":"Recent studies suggest that shift working may trigger health issues through disrupted circadian rhythms and altered eating habits. This study aimed to examine the possible associations of shift work with sleep quality, diet quality and obesity-related parameters. This study was conducted with 150 males (75 shift and daytime workers) aged 24-50 years. Dietary intake was determined using the 24-hour recall method, and dietary quality was evaluated using the Healthy Eating Index-2010 (HEI-2010). Anthropometrical measurements and body composition were assessed. The Pittsburgh Sleep Quality Index was used to evaluate sleep quality. Fasting and postprandial glucose and insulin, and fasting lipid levels were analyzed. HOMA-IR was calculated, and blood pressure was measured. The total HEI-2010 score of shift workers (52.6 [45.4-58.8]) was lower than the daytime workers (55.9 [49.1-64.9]) (p = 0.016). Among individuals with good sleep quality, the total HEI-2010 score, seafood and plant proteins, fatty acids, and sodium scores were lower in shift workers compared to others (p < 0.05 for each). Non-obese shift workers had higher body weight, waist circumference, waist/hip ratio, VLDL-cholesterol, triglyceride, postprandial glucose, and insulin levels compared to daytime workers (p < 0.05 for each). This study demonstrates that shift working is associated with lower diet quality independent of sleep quality.","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"1265-1274"},"PeriodicalIF":2.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142104915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0