{"title":"时间类型对抑郁的影响:反刍和感知压力的中介作用。","authors":"Haowen Zou, Xumiao Wang, Ciqing Bao, Hao Sun, Qiudong Xia, Zhilu Chen, Hongliang Zhou, Rui Yan, LingLing Hua, Domenica Veniero, Qing Lu, Zhijian Yao","doi":"10.1080/07420528.2025.2511263","DOIUrl":null,"url":null,"abstract":"<p><p>Chronotype represents an independent risk factor for depression, yet the psychological mechanisms underlying this association remain unclear. Potential mediators may include social jetlag (SJL), sleep quality, rumination, and perceived stress. Thus, this China-based study enrolled 122 patients with Depressive Episode (DE) and 126 healthy Controls (HC), assessing participants using: the Beck Depression Inventory (BDI), Morningness-Eveningness Questionnaire (MEQ), Munich Chronotype Questionnaire (MCTQ), Pittsburgh Sleep Quality Index (PSQI), Ruminative Response Scale (RRS), and Perceived Stress Scale (PSS). Partial Spearman correlations examined relationships between BDI scores, chronotype, sleep quality, rumination, and perceived stress within each group. Mediation analyses employed MEQ scores as the independent variable and diagnostic status (DE vs HC) as the dependent variable, with moderated mediation analyses assessing age, sex, and work status influences. Results revealed significant indirect effects of chronotype on depression status through: sleep quality, symptom rumination, brooding, reflective pondering, PSS scores, perceived helplessness, and perceived self-efficacy. These mediating effects were moderated by sex or work status, but not age. The demonstrated association between evening chronotype and increased depression risk suggests that clinical interventions targeting sleep improvement, rumination reduction, and stress coping enhancement may be particularly beneficial for such individuals experiencing depressive symptoms.</p>","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"864-878"},"PeriodicalIF":1.7000,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Impact of chronotype on depression: The mediating roles of rumination and perceived stress.\",\"authors\":\"Haowen Zou, Xumiao Wang, Ciqing Bao, Hao Sun, Qiudong Xia, Zhilu Chen, Hongliang Zhou, Rui Yan, LingLing Hua, Domenica Veniero, Qing Lu, Zhijian Yao\",\"doi\":\"10.1080/07420528.2025.2511263\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Chronotype represents an independent risk factor for depression, yet the psychological mechanisms underlying this association remain unclear. Potential mediators may include social jetlag (SJL), sleep quality, rumination, and perceived stress. Thus, this China-based study enrolled 122 patients with Depressive Episode (DE) and 126 healthy Controls (HC), assessing participants using: the Beck Depression Inventory (BDI), Morningness-Eveningness Questionnaire (MEQ), Munich Chronotype Questionnaire (MCTQ), Pittsburgh Sleep Quality Index (PSQI), Ruminative Response Scale (RRS), and Perceived Stress Scale (PSS). Partial Spearman correlations examined relationships between BDI scores, chronotype, sleep quality, rumination, and perceived stress within each group. Mediation analyses employed MEQ scores as the independent variable and diagnostic status (DE vs HC) as the dependent variable, with moderated mediation analyses assessing age, sex, and work status influences. 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引用次数: 0
摘要
睡眠类型是抑郁症的一个独立风险因素,但这种关联背后的心理机制尚不清楚。潜在的调节因素可能包括社会时差(SJL)、睡眠质量、反刍和感知压力。因此,本研究在中国招募了122名抑郁发作(DE)患者和126名健康对照(HC),使用贝克抑郁量表(BDI)、早晚性问卷(MEQ)、慕尼黑时间类型问卷(MCTQ)、匹兹堡睡眠质量指数(PSQI)、反思反应量表(RRS)和感知压力量表(PSS)对参与者进行评估。部分斯皮尔曼相关性研究了每组中BDI分数、睡眠类型、睡眠质量、反刍和感知压力之间的关系。中介分析采用MEQ评分作为自变量,诊断状态(DE vs HC)作为因变量,通过调节的中介分析评估年龄、性别和工作状态的影响。结果发现,睡眠质量、症状反刍、沉思、反思、PSS评分、感知无助感和感知自我效能感对抑郁状态有间接影响。这些中介效应受性别或工作状态的影响,但不受年龄的影响。夜间睡眠类型与抑郁风险增加之间的关联表明,针对改善睡眠、减少沉思和增强压力应对的临床干预可能对这些经历抑郁症状的个体特别有益。
Impact of chronotype on depression: The mediating roles of rumination and perceived stress.
Chronotype represents an independent risk factor for depression, yet the psychological mechanisms underlying this association remain unclear. Potential mediators may include social jetlag (SJL), sleep quality, rumination, and perceived stress. Thus, this China-based study enrolled 122 patients with Depressive Episode (DE) and 126 healthy Controls (HC), assessing participants using: the Beck Depression Inventory (BDI), Morningness-Eveningness Questionnaire (MEQ), Munich Chronotype Questionnaire (MCTQ), Pittsburgh Sleep Quality Index (PSQI), Ruminative Response Scale (RRS), and Perceived Stress Scale (PSS). Partial Spearman correlations examined relationships between BDI scores, chronotype, sleep quality, rumination, and perceived stress within each group. Mediation analyses employed MEQ scores as the independent variable and diagnostic status (DE vs HC) as the dependent variable, with moderated mediation analyses assessing age, sex, and work status influences. Results revealed significant indirect effects of chronotype on depression status through: sleep quality, symptom rumination, brooding, reflective pondering, PSS scores, perceived helplessness, and perceived self-efficacy. These mediating effects were moderated by sex or work status, but not age. The demonstrated association between evening chronotype and increased depression risk suggests that clinical interventions targeting sleep improvement, rumination reduction, and stress coping enhancement may be particularly beneficial for such individuals experiencing depressive symptoms.
期刊介绍:
Chronobiology International is the journal of biological and medical rhythm research. It is a transdisciplinary journal focusing on biological rhythm phenomena of all life forms. The journal publishes groundbreaking articles plus authoritative review papers, short communications of work in progress, case studies, and letters to the editor, for example, on genetic and molecular mechanisms of insect, animal and human biological timekeeping, including melatonin and pineal gland rhythms. It also publishes applied topics, for example, shiftwork, chronotypes, and associated personality traits; chronobiology and chronotherapy of sleep, cardiovascular, pulmonary, psychiatric, and other medical conditions. Articles in the journal pertain to basic and applied chronobiology, and to methods, statistics, and instrumentation for biological rhythm study.
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