Chronobiology International最新文献

Exploring chronotype, sleep disturbances, and temperament in adolescents with attention deficit hyperactivity disorder. 探索青少年注意缺陷多动障碍的时型、睡眠障碍和气质。

IF 2.2 4区医学

Chronobiology International Pub Date : 2025-05-29 DOI: 10.1080/07420528.2025.2511269

İrem Cihanyurdu Erdem, Aliye Tuğba Bahadır

{"title":"Exploring chronotype, sleep disturbances, and temperament in adolescents with attention deficit hyperactivity disorder.","authors":"İrem Cihanyurdu Erdem, Aliye Tuğba Bahadır","doi":"10.1080/07420528.2025.2511269","DOIUrl":"https://doi.org/10.1080/07420528.2025.2511269","url":null,"abstract":"This study aimed to explore sleep problems, chronotype, and temperament traits between adolescents with Attention Deficit Hyperactivity Disorder (ADHD) and healthy controls, and to examine how these variables relate within the ADHD group. One hundred and two adolescents with ADHD aged 11-17 recruited from Marmara University Pendik Training and Research Hospital Child and Adolescent Psychiatry Outpatient Clinic and 101 age and gender matched healthy controls participated in the study. Assessments included the Kiddie Schedule for Affective Disorders and Schizophrenia (K-SADS-PL), Junior Temperament and Character Inventory-Revised (J-TCI-R), Children's Chronotype Questionnaire (CCTQ), and Sleep Disturbance Scale for Children (SDSC). Adolescents with ADHD showed significantly higher rates of sleep disturbances and a greater prevalence of evening chronotype (63.7%) compared to controls. ADHD participants scored higher in novelty seeking and harm avoidance, while controls exhibited greater persistence and self-directedness. Notably, novelty seeking was pronounced in those with an evening chronotype and positively correlated with sleep disturbances, including difficulties initiating and maintaining sleep. Logistic regression analyses indicated that novelty seeking and age significantly predicted evening chronotype, while linear regression revealed that both novelty seeking and M/E scores predicted SDSC total scores. The findings underscore the clinical significance of addressing the interplay between chronotype, sleep disturbances, and temperament traits in adolescents with ADHD.","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"1-14"},"PeriodicalIF":2.2,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144179512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Estimation of sleep shortening and sleep phase advancing in response to advancing risetimes on weekdays. 工作日起床时间提前对睡眠缩短和睡眠阶段提前的影响。

IF 2.2 4区医学

Chronobiology International Pub Date : 2025-05-29 DOI: 10.1080/07420528.2025.2509629

Arcady A Putilov, Evgeniy G Verevkin, Dmitry S Sveshnikov, Zarina V Bakaeva, Elena B Yakunina, Olga V Mankaeva, Vladimir I Torshin, Elena A Trutneva, Michael M Lapkin, Zhanna N Lopatskaya, Roman O Budkevich, Elena V Budkevich, Marina P Dyakovich, Olga G Donskaya, Alexandra N Puchkova, Vladimir B Dorokhov

{"title":"Estimation of sleep shortening and sleep phase advancing in response to advancing risetimes on weekdays.","authors":"Arcady A Putilov, Evgeniy G Verevkin, Dmitry S Sveshnikov, Zarina V Bakaeva, Elena B Yakunina, Olga V Mankaeva, Vladimir I Torshin, Elena A Trutneva, Michael M Lapkin, Zhanna N Lopatskaya, Roman O Budkevich, Elena V Budkevich, Marina P Dyakovich, Olga G Donskaya, Alexandra N Puchkova, Vladimir B Dorokhov","doi":"10.1080/07420528.2025.2509629","DOIUrl":"https://doi.org/10.1080/07420528.2025.2509629","url":null,"abstract":"Since the circadian clocks cannot directly respond to the signals of social clocks, earlier risetimes on weekdays lead to loss of certain amount of sleep. However, these clocks can partly reduce this loss by advancing sleep phase due to advancing the pattern of 24-h exposure to light caused by earlier risetimes. In an in silico study, a model of sleep-wake regulation was applied to show that the difference between earlier and later weekday risers in weekday risetime is equal to the sum of differences between them in sleep loss and sleep phase advance that can be measured as their differences in weekend-weekday gap in risetime and in weekend risetimes, respectively. Such differences in sleep loss and sleep phase advance were estimated from bed- and risetimes self-reported for weekdays and weekends by 4940 university students and lecturers subdivided into subsamples with different weekday risetimes and chronotypes. We also estimated, for these subsamples, the percentages of weekday sleep insufficiency and circadian misalignment determined as a less than 6 hours in bed on weekdays and a larger than 3-h weekend-weekday gap in risetime, respectively. Additionally, advance phase shifts of the circadian clocks were predicted by model-based simulations of self-reported sleep times.","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"1-14"},"PeriodicalIF":2.2,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144180449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of chronotype on depression: The mediating roles of rumination and perceived stress. 时间类型对抑郁的影响：反刍和感知压力的中介作用。

IF 2.2 4区医学

Chronobiology International Pub Date : 2025-05-29 DOI: 10.1080/07420528.2025.2511263

Haowen Zou, Xumiao Wang, Ciqing Bao, Hao Sun, Qiudong Xia, Zhilu Chen, Hongliang Zhou, Rui Yan, LingLing Hua, Domenica Veniero, Qing Lu, Zhijian Yao

{"title":"Impact of chronotype on depression: The mediating roles of rumination and perceived stress.","authors":"Haowen Zou, Xumiao Wang, Ciqing Bao, Hao Sun, Qiudong Xia, Zhilu Chen, Hongliang Zhou, Rui Yan, LingLing Hua, Domenica Veniero, Qing Lu, Zhijian Yao","doi":"10.1080/07420528.2025.2511263","DOIUrl":"https://doi.org/10.1080/07420528.2025.2511263","url":null,"abstract":"Chronotype represents an independent risk factor for depression, yet the psychological mechanisms underlying this association remain unclear. Potential mediators may include social jetlag (SJL), sleep quality, rumination, and perceived stress. Thus, this China-based study enrolled 122 patients with Depressive Episode (DE) and 126 healthy Controls (HC), assessing participants using: the Beck Depression Inventory (BDI), Morningness-Eveningness Questionnaire (MEQ), Munich Chronotype Questionnaire (MCTQ), Pittsburgh Sleep Quality Index (PSQI), Ruminative Response Scale (RRS), and Perceived Stress Scale (PSS). Partial Spearman correlations examined relationships between BDI scores, chronotype, sleep quality, rumination, and perceived stress within each group. Mediation analyses employed MEQ scores as the independent variable and diagnostic status (DE vs HC) as the dependent variable, with moderated mediation analyses assessing age, sex, and work status influences. Results revealed significant indirect effects of chronotype on depression status through: sleep quality, symptom rumination, brooding, reflective pondering, PSS scores, perceived helplessness, and perceived self-efficacy. These mediating effects were moderated by sex or work status, but not age. The demonstrated association between evening chronotype and increased depression risk suggests that clinical interventions targeting sleep improvement, rumination reduction, and stress coping enhancement may be particularly beneficial for such individuals experiencing depressive symptoms.","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"1-15"},"PeriodicalIF":2.2,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144179859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A comprehensive examination of circadian rhythm and tryptophan pathway parameters: Assessing their role in predicting bipolar disorder in patients, siblings, and controls. 昼夜节律和色氨酸通路参数的综合检查：评估其在预测患者、兄弟姐妹和对照组双相情感障碍中的作用。

IF 2.2 4区医学

Chronobiology International Pub Date : 2025-05-29 DOI: 10.1080/07420528.2025.2509623

Emine Yavuz Ataşlar, Kürşat Altınbaş

{"title":"A comprehensive examination of circadian rhythm and tryptophan pathway parameters: Assessing their role in predicting bipolar disorder in patients, siblings, and controls.","authors":"Emine Yavuz Ataşlar, Kürşat Altınbaş","doi":"10.1080/07420528.2025.2509623","DOIUrl":"https://doi.org/10.1080/07420528.2025.2509623","url":null,"abstract":"The complex interplay between sleep, circadian rhythms, and tryptophan pathway metabolites in bipolar disorder (BD) remains poorly understood. This study examined these mechanisms in euthymic individuals with BD (n = 20), their unaffected siblings (n = 20), and healthy controls (n = 24). Subjective and objective sleep and circadian rhythm parameters were assessed using questionnaires and actigraphy, alongside plasma measurements of tryptophan (TRP), kynurenine (KYN), kynurenic acid (KYNA), 3-hydroxykynurenine (3-HK), 3-hydroxyanthranilic acid (3-HAA), and quinolinic acid (QUIN). Compared to controls, both BD patients and siblings showed reduced sleep efficiency and increased wake after sleep onset. Patients had longer time in bed, whereas siblings had shorter total sleep time. Elevated KYN/TRP ratios were found in both groups. Higher 3-HAA levels predicted both BD and sibling status, while increased QUIN levels were specific to BD. Lasso regression identified 12 variables associated with BD and 6 with sibling status. These results suggest that altered tryptophan metabolism and circadian disruption may contribute to the pathophysiology of BD and familial risk, providing potential biomarkers for early identification and intervention.","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"1-15"},"PeriodicalIF":2.2,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144181507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Morningness-Eveningness Questionnaire: Reliability and factorial structure of the full and reduced versions in Spanish adolescents. 早-晚性问卷：西班牙青少年完整版和简化版的信度和析因结构。

IF 2.2 4区医学

Chronobiology International Pub Date : 2025-05-28 DOI: 10.1080/07420528.2025.2509634

José Luís Manjón-Caballero, Juan F Díaz-Morales

引用次数: 0

Population-level analysis of circadian variations in blood cells. 血细胞昼夜节律变化的人群水平分析。

IF 2.2 4区医学

Chronobiology International Pub Date : 2025-05-28 DOI: 10.1080/07420528.2025.2511266

Patricia Fuentes-Bullejos, David Melguizo-Melguizo, María Carmen Lorenzo-Lozano, Alfonso Luis Blázquez-Manzanera

{"title":"Population-level analysis of circadian variations in blood cells.","authors":"Patricia Fuentes-Bullejos, David Melguizo-Melguizo, María Carmen Lorenzo-Lozano, Alfonso Luis Blázquez-Manzanera","doi":"10.1080/07420528.2025.2511266","DOIUrl":"https://doi.org/10.1080/07420528.2025.2511266","url":null,"abstract":"Knowledge of circadian rhythms is crucial in laboratory medicine to understand disease pathophysiologies and improve patient diagnoses and treatments. Here, we aim to determine whether circadian variations in blood cells are present at a population level and assess whether these rhythms are consistent with those reported previously in individuals. In a retrospective observational study we employed blood sample data analyzed at a local emergency laboratory over a period of 7 years, including the number of blood cells, time of sample collection, and patient age (between 18 and 85 years). Data showing cell counts outside the normal range were excluded, yielding a dataset consisting of 189,635 individual data points from 164,982 different patients. Records were grouped into 30-min intervals to determine their temporal distribution and average wave. We detected a circadian rhythm in all studied blood cell types (p < 0.01), with all except neutrophils peaking during the resting phase and exhibiting minimum values during the activity phase. Results were confirmed through parametric and nonparametric analyses. To the best of our knowledge, this is the first report of a significant circadian rhythm in blood cells at population level. The observed temporal variations at population level are comparable to those previously described for individuals.","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"1-7"},"PeriodicalIF":2.2,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144157152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The circadian rhythm of human body temperature - Clinical implications and review of the literature. 人体体温的昼夜节律-临床意义和文献综述。

IF 2.2 4区医学

Chronobiology International Pub Date : 2025-05-28 DOI: 10.1080/07420528.2025.2511268

Ivayla I Geneva

引用次数: 0

Validating an Arabic translation of the Sleep, Circadian Rhythms, and Mood (SCRAM) questionnaire. 验证睡眠，昼夜节律和情绪（SCRAM）问卷的阿拉伯语翻译。

IF 2.2 4区医学

Chronobiology International Pub Date : 2025-05-28 DOI: 10.1080/07420528.2025.2510501

Hessa Abdulla Bugahoos, Ameena Duaij Albinjasim, Yasmin AlMashouk, Abdulmajeed Abdullah Alghamdi, Achraf Ammar, Hadeel Ghazzawi, Khaled Trabelsi, Jamie Byrne, Michael V Vitiello, Haitham Jahrami

{"title":"Validating an Arabic translation of the Sleep, Circadian Rhythms, and Mood (SCRAM) questionnaire.","authors":"Hessa Abdulla Bugahoos, Ameena Duaij Albinjasim, Yasmin AlMashouk, Abdulmajeed Abdullah Alghamdi, Achraf Ammar, Hadeel Ghazzawi, Khaled Trabelsi, Jamie Byrne, Michael V Vitiello, Haitham Jahrami","doi":"10.1080/07420528.2025.2510501","DOIUrl":"https://doi.org/10.1080/07420528.2025.2510501","url":null,"abstract":"This study translated the Sleep, Circadian Rhythms, and Mood (SCRAM) questionnaire into Arabic and evaluated the psychometric properties and conceptual validity of the Arabic version. This process involved forward translation, back-translation, research team review, and pretesting of the Arabic SCRAM. A sample of 649 adults completed the Arabic SCRAM along with validation measures of sleep disturbances (Jenkins Sleep Scale: JSS) and depression severity (Patient Health Questionnaire: PHQ-9). Psychometric analyses included descriptive statistics, reliability analysis, test re-test, confirmatory factor analysis, and tests of convergent validity. The sample (77% female, mean age 26.31 years, range 18-47 years) demonstrated normal score distributions and adequate reliability on the Arabic SCRAM subscales. A three-factor structure was confirmed, aligning with the original English version. The Good Sleep and Depressed Mood subscales showed good convergence with the JSS and PHQ-9 scores, respectively. The Morningness subscale was not tested in the present research for convergent validity against other measures. The results provide preliminary support for a three-factor structure of the Arabic version of the SCRAM, with improved reliability indices (McDonald's ω ≈ 0.70) after removing three culturally non-optimal items; further validation is recommended before confirming these modifications.","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"1-13"},"PeriodicalIF":2.2,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144157156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chronotype and sleep disturbances: A comparative analysis of sluggish cognitive tempo and attention deficit hyperactivity disorder. 时间类型和睡眠障碍：迟缓的认知节奏和注意缺陷多动障碍的比较分析。

IF 2.2 4区医学

Chronobiology International Pub Date : 2025-05-26 DOI: 10.1080/07420528.2025.2509625

Yadigar Düğüncü Terlemez, Nagihan Cevher Binici, Ali Evren Tufan, Çisel Yazan Songür, Fatma Sibel Durak

{"title":"Chronotype and sleep disturbances: A comparative analysis of sluggish cognitive tempo and attention deficit hyperactivity disorder.","authors":"Yadigar Düğüncü Terlemez, Nagihan Cevher Binici, Ali Evren Tufan, Çisel Yazan Songür, Fatma Sibel Durak","doi":"10.1080/07420528.2025.2509625","DOIUrl":"https://doi.org/10.1080/07420528.2025.2509625","url":null,"abstract":"Recent investigations into Sluggish Cognitive Tempo (SCT), also known as Cognitive Disengagement Syndrome, have primarily focused on its association with ADHD. However, emerging evidence suggests SCT may be a distinct clinical entity, despite frequent co-occurrence with ADHD symptomatology. While ADHD studies have elucidated sleep patterns and chronotype preferences, SCT research has largely focused on ADHD-comorbid cases, providing limited data on community-based adolescents and adults. This study aims to investigate sleep disturbances and chronotype characteristics in individuals with pure SCT compared to those with ADHD and healthy controls within a clinical sample. We utilized the DSM-IV-based Disruptive Behavior Disorders Rating Scale (DBDRS-parent and teacher form), Barkley Sluggish Cognitive Tempo Scale (BSCTS), the Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime Version (K-SADS), Children's Sleep Habit Questionnaire, and Children's Chronotype Questionnaire for the evaluation of children with SCT, ADHD, and healthy controls. Our findings revealed shorter sleep duration in ADHD (n: 67) children compared to both SCT (n: 50) and healthy controls (n: 50), with no significant difference between SCT and healthy controls (p < 0.001). Eveningness tendencies were highest in SCT but also elevated in ADHD compared to controls (p < 0.001). Additionally, daytime sleepiness was highest in SCT and higher in ADHD than controls (p < 0.001). Regression analyses demonstrated that SCT severity predicted both daytime sleepiness and eveningness.","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"1-8"},"PeriodicalIF":2.2,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144141868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Abrupt change in the timing of the day/night negatively affects sleep behaviour and cognitive performance in diurnal zebra finches. 昼夜时间的突然变化会对昼行性斑胸草雀的睡眠行为和认知表现产生负面影响。

IF 2.2 4区医学

Chronobiology International Pub Date : 2025-05-23 DOI: 10.1080/07420528.2025.2506630

Ashwani Kumar, Mayank Kumar, Vatsala Tripathi, Abhilash Prabhat, Sanjay Kumar Bhardwaj

{"title":"Abrupt change in the timing of the day/night negatively affects sleep behaviour and cognitive performance in diurnal zebra finches.","authors":"Ashwani Kumar, Mayank Kumar, Vatsala Tripathi, Abhilash Prabhat, Sanjay Kumar Bhardwaj","doi":"10.1080/07420528.2025.2506630","DOIUrl":"https://doi.org/10.1080/07420528.2025.2506630","url":null,"abstract":"We investigated the consequence of abrupt directional shifts in the timing of light (hence darkness) period on sleep behaviour, novel object exploration and cognitive performance in diurnal zebra finches maintained under an equinox (12:12h LD) photoperiod. To two cohorts of birds (n = 80), the timing of 12 h light-on (hence of the darkness) for a week was either advanced by 6 h by reducing the dark period or delayed by 6 h by lengthening the dark period, with controls maintained on LD cycle as before. The first cohort of birds were examined for the effects on 24 h activity and feeding behaviors, while the second cohorts of birds were examined for the effects on sleep, neophobia and cognitive performance; the latter two were tested by the novel object exploration and spatial learning, respectively. The abrupt LD cycle shifts negatively affected sleep behaviour and cognition, as evidenced by behavioral and gene expression assays. There was a significant decrease in the mRNA expression levels of gene coding for the tyrosine hydroxylase (TH, the regulatory enzyme of the dopamine synthesis), cAMP response element binding protein (CREB), and brain-derived neurotrophic factor (BDNF) in hippocampus and TH alone in midbrain. These results support growing evidence of negative effects on behaviour and advanced brain functions in a diurnal species exposed to abrupt shifts in 24 h LD cycles.","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"1-13"},"PeriodicalIF":2.2,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144126870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0