Chronobiology International最新文献

{"title":"Validation of the Caen Chronotype Questionnaire: Exploring the added value of amplitude and correlations with actigraphy.","authors":"Robert Hickman, Daniel Lai Jie, Sukhi Shergill, Sylvain Laborde, Teresa C D'Oliveira","doi":"10.1080/07420528.2025.2471887","DOIUrl":"https://doi.org/10.1080/07420528.2025.2471887","url":null,"abstract":"<p><p>Chronotype self-report instruments are time and cost-efficient measures to profile diurnal or time-of-day preferences. The Caen Chronotype Questionnaire (CCQ) captures morningness and eveningness (CCQ-ME) and a circadian amplitude dimension for diurnal variation (distinctiveness; CCQ-DI). This study extends prior multilanguage validations for the English version of the CCQ. In total, 628 participants enrolled from a UK working population (mean age 30.34 ± 8.36 years, 61.3% female) including a subset of shift workers (<i>n</i> = 179; mean age 27.62 ± 5.95 years, 49.2% female). A subsample of participants also wore a consumer-grade actigraph device (Fitbit Charge 4) for seven days to compare chronotype estimates with objective sleep-wake parameters (<i>n</i> = 22; mean age 27.05 ± 3.99 years, 81.8% female, 90.9% worked standard daytime schedules, and 9.1% worked rotating shifts). All participants completed online chronotype measures, including the CCQ and Morningness-Eveningness Questionnaire (MEQ), depressive symptoms (Patient Health Questionnaire; PHQ-9), sleep quality (Pittsburgh Sleep Quality Index; PSQI), and other outcome measures. Results from the Confirmatory Factor Analysis (CFA) offer support for a two-factor structure of the CCQ in an English-speaking sample, highlighting how individual preferences for the timing of activities is associated with chronotype (morningness-eveningness; ME) and a second subjective amplitude dimension (DI). However, in contrast with the original CCQ structure, a more parsimonious solution and best overall fit involved the reduction of the original 16-item questionnaire (8 items per factor) to 4 ME items and 5 DI items. Convergent validity with the reduced CCQ scale (rME) and the MEQ was also established. The CCQ was sensitive in discriminating differences in actigraphic sleep-wake timings between morning-and evening-oriented individuals. Regression models demonstrated that amplitude (CCQ-DI) was a significant predictor explaining most of the variance in depressive symptoms (PHQ-9) compared to other variables. Overall, the English version of the CCQ was shown to be a robust tool in estimating chronotype in a sample of adults based in the UK.</p>","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"1-14"},"PeriodicalIF":2.2,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143556055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intra- and interspecific temporal mating patterns in <i>Anastrepha fraterculus</i> and <i>Anastrepha obliqua</i> fruit flies.","authors":"Samira Chahad-Ehlers, Jéssica Tagliatela, João Marcos de Oliveira, Lucas Packer Arthur, Reinaldo Alves de Brito","doi":"10.1080/07420528.2025.2471868","DOIUrl":"https://doi.org/10.1080/07420528.2025.2471868","url":null,"abstract":"<p><p>Daily rhythms, such as mating times, play a key role in shaping insect behavior and are pivotal in prezygotic reproductive isolation and speciation. To investigate whether mating behavior follows a daily rhythm under natural light-dark cycles and controlled temperature conditions, we examined the mating times of two related agricultural pest species, <i>Anastrepha fraterculus</i> and <i>Anastrepha obliqua</i>. Our observations revealed distinct patterns in their daily copulatory activities. <i>A. fraterculus</i> shows a unimodal pattern, peaking in the morning, while <i>A. obliqua</i> displays a bimodal pattern, with mating occurring in both the morning and late afternoon, all statistically validated. In <i>A. obliqua</i>, the morning peak is more pronounced before the winter solstice, reversing afterward. These results highlight the adaptability of these fruit flies' biological clocks, allowing them to adjust mating timing according to seasonal environmental changes. Our findings also reveal how each species gauges environmental light-dark durations, even if annual variation is less pronounced in tropical regions, with twilight serving as a daily marker. The observed plasticity, including phase shifts in both species and amplitude changes in <i>A. obliqua</i>, emphasizes their synchronization with environmental cycles, which may explain the absence of specific pre-mating behaviors and the initiation of mating in low-light conditions, as seen in <i>A. fraterculus</i>. This study underscores the importance of biological rhythm plasticity in understanding fruit fly mating behavior, with implications for population management and ecological dynamics, and reinforces the need for 24-h observations to capture these rhythms fully.</p>","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"1-18"},"PeriodicalIF":2.2,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143540409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Light levels in a modern intensive care unit: Impact of time of year, window directionality, and outdoor light levels.","authors":"Nikhil Chilakapati, Liz Timple, Sophia Pizzi, Janelle M Fine, Hirsh Makhija, Lauryn K Bruce, Robert L Owens, Douglas Alden, Atul Malhotra, Jennifer L Martin, Biren B Kamdar","doi":"10.1080/07420528.2025.2469885","DOIUrl":"10.1080/07420528.2025.2469885","url":null,"abstract":"<p><p>The intensive care unit (ICU) environment is designed for the care of acutely ill patients, with lighting conditions reflecting the needs of the busy clinical setting. Earlier ICU studies suggested that daytime and nighttime light levels were misaligned with those required for circadian rhythm entrainment, which can impact patient sleep-wake cycles and recovery from critical illness. In this investigation in San Diego, California, a coastal US city with over 260 days of sunshine annually, we performed a detailed evaluation of light levels in a contemporary academic medical-surgical ICU constructed in 2016, which features modern lighting and floor-to-ceiling windows in each of the 24 rooms. Using light meters mounted on poles and located directly behind the head of each patient's bed, our analysis of nearly 90,000 hours of data revealed daytime ICU light levels consistently lower than 150 lx, similar to studies in older ICUs and many magnitudes lower than outdoor levels at identical times. Hence, despite the modern design, we found that little to no light from the ~100 ft² windows reached the patient. While daytime light levels were low across all ICU rooms, those with windows facing South and Northwest featured higher light levels than those facing Southeast and Northeast, suggesting a contribution of window direction to ICU light levels.</p>","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"1-9"},"PeriodicalIF":2.2,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143491010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relevance of morning affect, eveningness and distinctness in regard to the mental health of adolescents.","authors":"Yaiza Puig-Navarro, Arturo Arrona-Palacios, Juan F Díaz-Morales","doi":"10.1080/07420528.2025.2469870","DOIUrl":"https://doi.org/10.1080/07420528.2025.2469870","url":null,"abstract":"<p><p>Previous studies conducted in adults indicated that the distinctness, that is, the subjective feeling of fluctuations in mood and activation - was associated with health to a greater extent than were morning affect and eveningness, but few studies have examined these relationships among adolescents. A sample of 342 Spanish adolescents (11-14 years; 44.7% girls) were assessed for morning affect, eveningness, distinctness, health-related quality of life, life satisfaction, depression symptoms, sleep habits, and self-reported academic performance. The results indicated that distinctness was associated with worse health indicators. Girls reported higher scores on distinctness and depressive symptoms whereas boys reported higher scores on morning affect, life satisfaction, physical well-being and psychological well-being. The interaction between distinctness and sex indicated that girls with greater distinctness reported greater depression, lower physical and psychological well-being, and less autonomy. The interaction between morning affect and sex indicated that girls with greater morning affect reported lower peer and social support. The results obtained in this study underline the influence of distinctness on daily functioning, especially in girls, and highlight how this characteristic is related to other aspects of health. These findings suggest that the subjective feeling of fluctuations in mood and activation during the day may have a greater impact on adolescents' quality of life than do morning affect and eveningness, highlighting the importance of considering the circadian component of distinctness when designing programs to improve adolescent health.</p>","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"1-11"},"PeriodicalIF":2.2,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143482246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between chrononutrition profile, social jet lag and obesity: A cross-sectional study of Chinese college students.","authors":"Yue Gong, Ji-Xin Zhang, Sheng-Nan Li, Le-Le Li, Xiao-Jie Dong, Ling-Jie Liu, Ze-Hui Fan, Yan Li, Yi-De Yang","doi":"10.1080/07420528.2025.2464664","DOIUrl":"https://doi.org/10.1080/07420528.2025.2464664","url":null,"abstract":"<p><p>This study aimed to investigate the associations between chrononutrition profile, social jet lag (SJL) with obesity-related indicators (body mass index (BMI), waist circumference (WC), waist-to-height ratio (WHTR), and percentage of body fat (PBF)). This cross-sectional study was conducted among college students in a university in Hunan Province, China, from 14 September 2023 to 8 June 2024. This study employed the Chrononutrition Profile - Questionnaire (CP-Q) along with physical examinations. SJL was defined as time difference of midpoint of sleep between the workdays and freedays. Sleep-corrected SJL (SJL_sc) is the absolute difference between the sleep onset on free days and workdays. Average evening latency is the time between the last meal of the day and bedtime. Eating jet lag is the difference in the midpoint of the eating window between workdays and freedays. Logistic regression was utilized to assess the associations between chrononutrition profile, SJL, and obesity-related indicators among college students. A total of 805 participants were recruited, of which 695 have complete data after excluding those who did not meet the inclusion criteria. After adjusting for potential covariates, average evening latency <4 h was related with lower risk of high BMI, WC, and PBF [<i>OR</i> (95% CI) = 0.435 (0.285-0.663), 0.508 (0.305-0.848), 0.564 (0.402-0.792), respectively]. Average eating window >12 h was associated with a lower risk of high BMI, WC, and PBF [<i>OR</i> (95% CI) = 0.511 (0.327-0.800), 0.485 (0.277-0.851), 0.651 (0.456-0.930), respectively]. Last eating occasion jet lag >1 h was a higher risk of high PBF [<i>OR</i> (95% CI) = 1.554 (1.018-2.371)]. SJL_sc > 1 h was associated with high PBF [<i>OR</i> (95% CI) = 1.527 (1.073-2.174)]. Circadian rhythm disruptions, including SJL and eating jet lag, are prevalent among college students. Long eating window, short evening latency, is associated with low risk of obesity, while short sleep duration, last eating occasion jet lag and larger SJL_sc were associated with higher risk of obesity among youths.</p>","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"1-12"},"PeriodicalIF":2.2,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143398359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factor structure of the Brazilian version of the Morningness-Eveningness Scale for Children (MESC) for chronotype assessment in adolescents.","authors":"Cristina Brust, Andreia Meneghetti, Andreia Pelegrini, Thais Silva Beltrame, Diego Grasel Barbosa, Rubian Diego Andrade, Érico Pereira Gomes Felden","doi":"10.1080/07420528.2025.2462155","DOIUrl":"https://doi.org/10.1080/07420528.2025.2462155","url":null,"abstract":"<p><p>To translate and adapt the Morningness-Eveningness Scale for Children into Brazilian Portuguese, translation, back-translation, technical review, expert evaluation, focus group, test-retest, and factorial structure of the instrument were performed. The total sample consisted of 676 students from the 6th to 9th grade of elementary school and from the 1st to 3rd year of high school, aged between 10 and 19 years, 343 girls (51%) and 333 boys (49%), with a mean age of 13.98 (2.00) years. Of these, 40 students from the 6th grade, aged between 10 and 13 years, participated in the test-retest, 24 girls (60%) and 16 boys (40%), with a mean age of 11.17 (0.50) years. Descriptive and inferential analyses were performed, including exploratory and confirmatory factor analyses. High levels of internal consistency (α = 0.742) and test-retest (0.974) were obtained, in addition to high values for clarity of language (0.88), practical relevance (1.00) and theoretical relevance (1.00). In the confirmatory factor analysis, the model presented satisfactory validity indices: χ2 = 40.811 (df = 34), <i>p</i> = 0.196, RMSEA = 0.025 (90% CI: <0.001-0.049), CFI = 0.990 and TLI = 0.987, with no need for adjustments between the covariances between the items. Therefore, the MESC-BR was considered an adequate instrument to assess circadian preferences in Brazilian adolescents, given its test-retest psychometric properties and construct validity.</p>","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"1-9"},"PeriodicalIF":2.2,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143381734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Circadian rhythm and lithium response in bipolar disorder: Insights from actigraphy and NR1D1 polymorphism.","authors":"Ekrem Furkan Uçak, Kürşat Altınbaş, Nadir Koçak, Ahmet Güleç","doi":"10.1080/07420528.2025.2455139","DOIUrl":"10.1080/07420528.2025.2455139","url":null,"abstract":"<p><p>Lithium has long been used as a cornerstone mood stabilizer in the treatment of bipolar disorder (BD). However, reliable biomarkers that can predict which patients will respond better to lithium are still lacking. This study aims to evaluate the potential of NR1D1 gene SNP; rs2071427 and actigraphic measurements in predicting lithium response. Thirty-one patients diagnosed with BD at Selçuk University Faculty of Medicine and who were euthymic for at least 8 weeks were included in the study. Sleep-wake cycles and circadian rhythms of the participants were monitored by actigraph for approximately 1 week. For genetic analyses, the SNP rs2071427 variant of the NR1D1 gene was evaluated. A significant proportion of patients with homozygous (AA/GG) genotypes responded well to lithium, whereas some patients with heterozygous (AG) genotypes did not respond to lithium. Actigraphic data showed that there were marked variations in the sleep patterns of BD patients. The Morningness-Eveningness Questionnaire scale did not adequately discriminate the morning chronotype. Seasonal Pattern Assessment Questionnaire results showed that most patients had a seasonal pattern, but this was insufficient to predict response to lithium. This study once again demonstrates the need for new biomarkers to predict lithium response. The findings are an important step in the personalization of BD treatment and may improve treatment efficacy and minimize side effects by tailoring the treatment process to the individual characteristics of patients. Future studies should support these findings with larger sample groups and studies on different genetic markers.</p>","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"225-234"},"PeriodicalIF":2.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143000564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of circadian rhythms on retinal immunity.","authors":"He Ren, Yilin Yuan, Danlei Zhang, Yiqiao Xing, Zhen Chen","doi":"10.1080/07420528.2025.2460675","DOIUrl":"10.1080/07420528.2025.2460675","url":null,"abstract":"<p><p>The eye is an immune-protected organ, which is driven by factors such as cytokines, chemicals, light, and mechanical stimuli. The circadian clock is an intrinsic timing mechanism that influences the immune activities, such as immune cell count and activity, as well as inflammatory responses. Recent studies have demonstrated that the eye also possesses an intrinsic circadian rhythm, and this rhythmic regulation participates in ocular immune modulation. In this review, we discuss the immunoregulatory mechanisms of the circadian clock within the eye, and reveal new perspectives for the prevention and treatment of ocular diseases.</p>","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"198-212"},"PeriodicalIF":2.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143363760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of caffeinated coffee on physical and cognitive performance: Chronotype and time of day study.","authors":"Yakup Köse, Raci Karayigit, Muhammed Uygar Sertkaya","doi":"10.1080/07420528.2025.2460654","DOIUrl":"10.1080/07420528.2025.2460654","url":null,"abstract":"<p><p>This study examined the effects of caffeinated coffee (3 mg/kg) compared to decaffeinated coffee (placebo) on physical and cognitive performance in trained male athletes with morning (MT) and evening (ET) chronotypes, all of whom had moderate caffeine intake. Seventeen trained male athletes participated in various tests, including CP (a flanker task), hand grip strength test, back strength test, lower body Wingate sprint tests (peak and average power), and rating of perceived exertion (using the Borg Scale). The tests were conducted at two times of day: mornings (08:00 h-10:00 h) and evenings (16:00 h-18:00 h). Results indicated that caffeinated coffee significantly enhanced handgrip strength [F(1, 15) = 11.200, <i>p</i> = 0.001, η²p = .427], back strength [F(1, 15) = 8.695, <i>p</i> = 0.001, η²<i>p</i> = 0.367], and lower body Wingate test performance, including peak strength [F(1, 15) = 8.384, <i>p</i> = 0.001, η²p = 0.359] and mean strength [F(1, 15) = 8.304, <i>p</i> = 0.001, η²p = 0.356], regardless of chronotype. Conversely, no significant differences were observed in the cognitive performance (CP) measured by the flanker task and in Borg's perceived exertion ratings. When analyzing the interaction between groups × CAF & PLA, significant differences were found in the handgrip strength test [F(3, 45) = 17.443, <i>p</i> = 0.001, η²p = 0.538], back strength test [F(3, 45) = 19.926, <i>p</i> = 0.001, η²p = 0.571], peak power [F(3, 45) = 12.285, <i>p</i> = 0.001, η²p = 0.450], and average power [F(3, 45) = 6.633, <i>p</i> = 0.009, η²p = 0.307]. However, no significant differences were noted in cognitive performance (CP) and Borg perceived exertion ratings. These findings suggest that chronotype, timing of training, and caffeine consumption can significantly influence physical performance in trained men with moderate caffeine intake.</p>","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"282-296"},"PeriodicalIF":2.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143188429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Self-reported preferences for seasonal daylight saving time meet fundamentals of human physiology: Correlations in the 2018 public consultation by the European Commission.","authors":"José María Martín-Olalla, Jorge Mira","doi":"10.1080/07420528.2025.2456562","DOIUrl":"10.1080/07420528.2025.2456562","url":null,"abstract":"<p><p>We analyze the results to question 2 (individual preferences for cancelling or keeping the current clock regulations) from the 2018 Public Consultation on summertime arrangements (DST) conducted by the European Commission. We reveal correlations in the shares of population for cancelling the regulations and the winter sunrise time (SRW) [<i>R</i>² = 0.177; <i>p</i> = 0.03; <i>N</i> = 25] and the onset of human activity [<i>R</i>² = 0.677; <i>p</i> = 5 × 10^-5; <i>N</i> = 17]. The results are in line with the rationale behind the regulations in the range of latitude 35 to 63: larger values of SRW (larger latitude) brought larger shares against the regulations; and earlier onset of human activity relative to SRW brought larger shares against the regulations. The shares for cancelling the regulation did not show correlations with time offset (position in time zone), thus challenging the current view within the circadian community.</p>","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"157-161"},"PeriodicalIF":2.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143045644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}