Chronobiology International最新文献

{"title":"Sleep quality and cognitive disengagement syndrome as sequential mediators linking chronotype to ADHD symptom dimensions in adults with attentional complaints.","authors":"Beyza Erdogan Akturk, Omer Kaptanoglu, Meltem Insel Kaptanoglu","doi":"10.1080/07420528.2026.2710230","DOIUrl":"10.1080/07420528.2026.2710230","url":null,"abstract":"<p><p>Evening chronotype is overrepresented in adults with attention-deficit/hyperactivity disorder (ADHD), yet how circadian preference relates to specific symptom dimensions remains unclear. Cognitive Disengagement Syndrome (CDS; formerly Sluggish Cognitive Tempo), characterized by daydreaming, mental fogginess, and hypoarousal, is considered distinct from ADHD despite overlap and may be relevant to associations among chronotype, sleep, and attentional symptoms. This cross-sectional study tested an a priori serial mediation model in 100 treatment-seeking adults with attentional complaints and no prior ADHD diagnosis or pharmacotherapy. Participants completed the Morningness-Eveningness Questionnaire, Pittsburgh Sleep Quality Index, Barkley Adult Sluggish Cognitive Tempo Rating Scale, and Adult ADHD Self-Report Scale (ASRS-v1.1). Eveningness was associated with poorer sleep quality, and poorer sleep quality with higher CDS symptoms. CDS was strongly associated with both inattention and hyperactivity/impulsivity. The serial indirect effects through sleep quality and CDS were significant for both dimensions, whereas simple indirect effects were not. The full models explained 50.0% and 21.3% of the variance in inattention and hyperactivity/impulsivity, respectively. Supplementary analyses localized this effect to the Daydreaming rather than Sluggishness subdimension. Findings were robust to age- and sex-adjustment. These findings suggest sleep quality and CDS are clinically relevant correlates of ADHD symptom dimensions, though longitudinal confirmation is needed.</p>","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"1463-1474"},"PeriodicalIF":2.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148599628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationships between rest-activity rhythms, cancer-related fatigue, and quality of life: Results from a time-restricted eating randomized controlled trial.","authors":"Amber S Kleckner, Yuanyuan Zhou, Yancy Diaz-Mercado, Jin-Oh Hahn, Ian R Kleckner, Shijun Zhu","doi":"10.1080/07420528.2026.2669594","DOIUrl":"10.1080/07420528.2026.2669594","url":null,"abstract":"<p><p>Circadian rest-activity rhythms, or a person's consistency in their daily activity and rest patterns, can be quantified using various parametric and non-parametric methods. However, these methods are seldom applied to understand symptoms in cancer survivorship. This study examined associations between various rest-activity rhythm parameters and cancer-related fatigue and quality of life. Adult cancer survivors (<i>n</i> = 31) were enrolled in a 12-week randomized clinical trial of individualized nutrition counseling with or without time-restricted eating. Participants wore actigraphy watches continuously for 3-7 days at baseline, 6 weeks, and 12 weeks. Rest-activity parameters were derived using cosinor models, traditional non-parametric methods, and probabilistic hidden Markov models (HMMs). Participants completed the Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F) questionnaire, including physical, social, emotional, and functional well-being subscales; fatigue; and a quality-of-life total score. Mixed models revealed that stronger rest-activity rhythms were generally associated with lower fatigue and greater well-being in several dimensions. Specifically, intradaily variability and the HMM-derived rhythm index were positively associated with emotional well-being (<i>p</i> = 0.040 and <i>p</i> = 0.037, respectively, medium effect sizes). Earlier daily activity peaks, identified through both parametric and non-parametric methods, were linked to greater emotional well-being (e.g. cosinor peak time and emotional well-being, <i>p</i> = 0.006, large effect size; start hour of the most active 10 hours, <i>p</i> = 0.004, large effect size). There was no effect of group (time-restricted eating vs. control) on any of the rest-activity parameters. Findings suggest that rest-activity rhythm parameters, including those derived from novel HMMs, may serve as useful biomarkers of fatigue and various dimensions of well-being, supporting further research in larger samples and potential clinical application.</p>","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"1359-1372"},"PeriodicalIF":2.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13383890/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147940237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mediating effect of sleep hygiene between morningness-eveningness preferences and psychological distress among a sample of Lebanese adults.","authors":"Nada Akiki, Souheil Hallit, Diana Malaeb, Fouad Sakr, Mariam Dabbous, Sahar Obeid, Feten Fekih-Romdhane, Rabih Hallit","doi":"10.1080/07420528.2026.2670688","DOIUrl":"10.1080/07420528.2026.2670688","url":null,"abstract":"<p><p>Our study explored the mediating effect of sleep hygiene between morningness-eveningness preferences and psychological distress among a sample of Lebanese adults. A total of 948 Lebanese participants were enrolled in this cross-sectional study (mean age 26.93 ± 10.23 years). A self-administered survey was dispersed using the snowball sampling technique. The survey consisted of socio-demographic characteristics along with the following Arabic validated instruments: The Morningness-Eveningness Questionnaire (MEQ), the Patient-Health Questionnaire (PHQ-4), and the Sleep Hygiene Index (SHI). Statistical analysis was performed using SPSS v.27 with mediation analysis via PROCESS MACRO v.42 Model 4. Sleep hygiene fully mediated the relationship between morningness-eveningness preferences and psychological distress. Greater morningness preferences were significantly associated with better sleep hygiene (i.e. lower sleep hygiene scores). In turn, poor sleep hygiene (i.e. higher sleep hygiene scores) was significantly associated with higher psychological distress. The direct association between morningness and psychological distress was not statistically significant. Our study offered insight on important connections between sleep hygiene, morningness-eveningness preferences, and psychological distress within the Lebanese context. These results highlight the necessity of promoting healthy sleep behaviors and chronobiological awareness to improve mental health in this population.</p>","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"1401-1410"},"PeriodicalIF":2.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global bibliometric trends in shrimp chronobiology: From behavioral rhythms to precision aquaculture frontiers.","authors":"Rafael Queiroz-Anjos","doi":"10.1080/07420528.2026.2674043","DOIUrl":"10.1080/07420528.2026.2674043","url":null,"abstract":"<p><p>The global expansion of intensive shrimp farming confronts a physiological paradox: while production systems become increasingly technological, management protocols often disregard the temporal dimension of crustacean physiology. This study presents a comprehensive bibliometric analysis of shrimp chronobiology based on 197 Scopus-indexed publications (1943-2026). Network analysis reveals a conceptual transition from descriptive ecological studies (1950s-1990s) focused on tidal rhythms and catchability to a contemporary molecular frontier (2015-2025) driven by transcriptomics, clock gene expression, and immune-circadian interactions. Keyword co-occurrence analysis identified four structural clusters: Production/Feeding, Behavior/Locomotion, Molecular Physiology, and Toxicology. Analysis of the most-cited and recent articles demonstrates that while light and feeding have been validated as primary zeitgebers, a critical knowledge gap persists regarding circadian regulation of osmotic stress. Despite the dominance of inland low-salinity farming, none of the top-ranked studies investigated rhythmic osmoregulation. We identify the lack of research on circadian regulation of osmotic stress as a significant knowledge gap and propose a research agenda integrating chronobiology into precision aquaculture to optimize metabolic efficiency and disease resistance.</p>","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"1332-1342"},"PeriodicalIF":2.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147970888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Resting energy expenditure and substrate oxidation do not differ between night and day shift workers: A real-life study.","authors":"Kely R C Teixeira, Luana Thomazetto Rossato, Flávia M S de Branco, Jordane A Mendes, Luciana A de Medeiros, Thúlio M Cunha, Laura Cristina Tibiletti Balieiro, Erick P de Oliveira, Cibele A Crispim","doi":"10.1080/07420528.2026.2670685","DOIUrl":"10.1080/07420528.2026.2670685","url":null,"abstract":"<p><p>This cross-sectional study investigated differences in resting energy expenditure (REE), respiratory quotient (RQ), and substrate utilization between night and day shift workers. A total of 62 male workers (30-night shift, 32 d shifts), aged 21 to 62 y, were assessed for anthropometric measurements, sleep parameters, social jetlag, and daytime sleepiness. Indirect calorimetry was used to evaluate REE, RQ, and carbohydrate and fat oxidation. Linear regression models and Generalized Estimating Equations (GEE) were applied, adjusting for potential confounders. Night shift workers exhibited lower RQ and carbohydrate oxidation and higher fat oxidation compared to day shift workers after adjusting for age. However, after further adjustment for workload, no significant differences in REE were observed (night: 1843.31 [1737.21-1931.42] kcal/day; day: 1732.74 [1639.58-1825.91] kcal/day, <i>p</i> = 0.133), RQ (night: 0.88 [0.86-0.91]; day: 0.90 [0.88-0.93], <i>p</i> = 0.331), or substrate oxidation rates - carbohydrate oxidation (g/min: night: 0.20 [0.18-0.23]; day: 0.21 [0.19-0.24], <i>p</i> = 0.583) and fat oxidation (g/min: night: 0.04 [0.03-0.06]; day: 0.03 [0.02-0.04], <i>p</i> = 0.134) - between night and day shift workers. Night shift work does not differ from day shift work in terms of REE and substrate oxidation. Further longitudinal studies with larger samples are needed to confirm these findings.</p>","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"1393-1400"},"PeriodicalIF":2.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147867024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of chronotype on nutritional status and eating behaviors among university students of Pakistan.","authors":"Aqsa Naseem, Mahpara Safdar","doi":"10.1080/07420528.2026.2674039","DOIUrl":"10.1080/07420528.2026.2674039","url":null,"abstract":"<p><p>Chronotype reflects individual differences in circadian rhythm-related behaviors, including food consumption and sleep pattern. University students often follow irregular schedules, increasing the risk of unhealthy eating behaviors and obesity. This cross-sectional study aimed to examine chronotype prevalence and its association with eating behaviors and nutritional status among Pakistani university students. Chronotype was assessed using the Morningness Eveningness Questionnaire (MEQ). Eating behavior was evaluated using a 3-d dietary recall, while anthropometry, physical activity (IPAQ), and sleep habits were also recorded. Pearson chi-square, one-way ANOVA, Pearson correlation was applied. Among 345 students, 63.2% were males and 36.8% were females, with chronotype distributed as 57.1% intermediate, 26.4% morning, and 16.5% evening. Evening chronotypes exhibited unhealthy eating behaviors including meal skipping, delayed meal timings, unhealthy snacking and the lowest breakfast energy (<i>p</i> ≤ 0.05). Morning chronotypes showed a higher intake of fruit and milk, whereas evening chronotypes, particularly males had lower intake of fiber, magnesium, iron, zinc, phosphorus (<i>p</i> ≤ 0.05). However, there was no significant association between chronotype and nutritional status (<i>p</i> ≥ 0.05). In conclusion, chronotype influenced students' eating behaviors, highlighting the need to consider circadian preferences when promoting healthy dietary habits and long-term metabolic health.</p>","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"1431-1443"},"PeriodicalIF":2.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147970859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Machine learning approaches in predicting circadian rhythm sleep-wake disorders: A review.","authors":"Trina Sengupta, Archana Gaur, Sakthivadivel Varatharajan","doi":"10.1080/07420528.2026.2667404","DOIUrl":"10.1080/07420528.2026.2667404","url":null,"abstract":"<p><p>Circadian rhythm sleep-wake disorders (CRSWDs) arise from misalignment between an individual's sleep-wake timing and endogenous circadian physiology, with substantial consequences for sleep health and overall well-being. In the era of sleep-omics and digital phenotyping, machine learning (ML) offers powerful tools for modelling complex, high-dimensional circadian data; however, its application to CRSWD prediction remains under developed. This systematic review aims to synthesize current evidence on the use of ML approaches for circadian phase estimation and CRSWD classification in humans. We have conducted a systematic search of PubMed, ScienceDirect, PsycINFO, Cochrane Library, and Google Scholar for studies published between January 2011 and May 2025. Eligible studies focused on sighted adults where ML algorithms predicted circadian phase or classified CRSWDs. Data sources included sleep diaries, actigraphy, genomics, and biological markers. To maintain model homogeneity and account for physiological differences, studies involving pediatric populations, neurodegenerative comorbidities, or blind individuals were excluded. A total of 22 studies met the inclusion criteria. Across studies, ML models demonstrated promise for circadian phase estimation and CRSWD classification using diverse data modalities, including wearable-derived time-series data and multimodal features. However, the evidence base remains limited by small sample sizes, methodological heterogeneity, limited external validation, and inconsistent reporting standards. Overall, current findings suggest that while ML-based approaches hold significant potential for advancing CRSWD detection and personalized circadian medicine, more robust, standardized, and generalizable models are required. Future research should prioritize larger multimodal datasets, transparent validation strategies, and clinically translatable tools to support scalable CRSWD screening and diagnosis.</p>","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"1316-1331"},"PeriodicalIF":2.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Earlier bedtime misalignment is associated with increased severity of chemotherapy-induced hot flashes in premenopausal women with breast cancer.","authors":"Sun Hyung Lee, Sanghyup Jung, Geun Hui Won, Jaehyun Kim, Saim Jung, Chan-Woo Yeom, Kwang-Min Lee, Kyung-Lak Son, Jang-Il Kim, Sook Young Jeon, Han-Byoel Lee, Bong-Jin Hahm, Joon Sung Shin","doi":"10.1080/07420528.2026.2723196","DOIUrl":"https://doi.org/10.1080/07420528.2026.2723196","url":null,"abstract":"<p><p>Chemotherapy-induced hot flashes (CIHFs), a vasomotor symptom that has been demonstrated to impair the quality of life in breast cancer patients, have been associated with circadian rhythms. While circadian misalignment has been shown to contribute to chemotherapy-related adverse effects, the link between bedtime misalignment (BM) and these effects remains unclear. The objective of this study was to evaluate BM based on objective measurements and determine whether CIHF severity differs according to BM. A total of 35 premenopausal women with breast cancer awaiting chemotherapy were evaluated for BM using actigraphy. Participants were categorized into the earlier misaligned group (\"going to bed earlier than preferred bedtime\") and the aligned/later misaligned group (\"going to bed at or later than preferred bedtime\"). CIHF was assessed using 7-day diaries at baseline, at one month post-chemotherapy (T1), and at nine months post-chemotherapy. The habitual bedtime (p = 0.032) and the degree of BM (p < 0.001) measured by actigraphy differed between the earlier misaligned group and the aligned/later misaligned group. The earlier misaligned group reported significantly higher burden of CIHF, including total hot flash score (p = 0.004), daytime and nighttime sweating scores (both p < 0.001), and daytime hot flash frequency (p = 0.007) compared with the aligned/later misaligned group at T1. Premenopausal women whose habitual bedtime was earlier than their preferred bedtime experienced greater burden of CIHF. Our findings indicate the potential for BM to contribute to vasomotor vulnerability in patients with breast cancer. Further studies are needed to elucidate the mechanisms by which BM contributes to CIHF.</p>","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"1-11"},"PeriodicalIF":2.5,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148817686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of organic light-emitting diode on nighttime task performance and melatonin secretion: Randomized controlled trials.","authors":"Yurika Sawaki, Tomoki Kubo, Yoichi Yamaguchi, Yuki Yamagami, Keigo Saeki, Kenji Obayashi","doi":"10.1080/07420528.2026.2723201","DOIUrl":"https://doi.org/10.1080/07420528.2026.2723201","url":null,"abstract":"<p><p>This study aimed to determine whether organic light-emitting diode (OLED) lighting with low intensity and color temperature (150 lux, 3000 K) maintains nighttime task performance and reduces melatonin suppression compared with a generally used LED lighting with high intensity and color temperature (750 lux, 5000 K). We conducted two randomized crossover trials. <i>Study 1</i> included 39 adults who answered the Uchida-Kraepelin test (UKT) within 2 h under the OLED and LED conditions; <i>Study 2</i> included 30 men whose salivary melatonin levels were measured in 5-h exposure to the aforementioned conditions. The mean number of UKT answers and errors, melatonin suppression, and changes in melatonin levels from the baseline were compared between the two conditions. No significant differences were observed in the mean number of UKT answers and errors between the OLED and LED conditions. Noninferiority analysis revealed that the OLED lighting was not inferior to the LED lighting in terms of the mean number of answers (LED: mean, 835.7; noninferiority margin, 116.2; OLED: 95% confidence interval, 745.3-902.4). Furthermore, OLED reduced the overall melatonin suppression by 56.1% compared with LED. Similarly, multilevel analysis revealed significantly lower reduction in salivary melatonin, by 5.7 pg/mL, in OLED than in LED. In conclusion, we demonstrated that melatonin suppression was significantly reduced without reducing nighttime task performance in the OLED lighting condition compared with generally used LED lighting condition. Further studies, including comparisons between OLED lighting and LED lighting under the same conditions, are warranted to better understand the effect of OLED on nighttime task performance and melatonin suppression.</p>","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"1-11"},"PeriodicalIF":2.5,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148817671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CosinorOnline: A free web-based platform for cosinor analysis, validated using simulated datasets and demonstrated using cardiovascular recordings from a prenatal hypoxia model.","authors":"Lubos Molcan","doi":"10.1080/07420528.2026.2720596","DOIUrl":"https://doi.org/10.1080/07420528.2026.2720596","url":null,"abstract":"<p><p>Cosinor analysis remains a fundamental statistical method in chronobiology for quantifying rhythmic patterns. However, many existing tools require specialised programming knowledge or local software installation, creating barriers for clinicians and students. This paper presents the updated CosinorOnline platform, a free browser-based implementation of the established single-component cosinor method designed for accessible rhythmic data analysis. To verify the numerical correctness of the software implementation, CosinorOnline was benchmarked against the reference cosinor2 R package using 2,016 simulated datasets. Mathematical validation was complemented by a cross-platform software benchmark using representative hourly heart-rate profiles derived from continuous radiotelemetric recordings from one control and one prenatally hypoxic rat exposed to endotoxin challenge to verify numerical agreement under realistic physiological conditions. Results demonstrated excellent numerical agreement with established R-based frameworks (Mean Absolute Error <math><mrow><mo><</mo><msup><mn>10</mn><mrow><mo>-</mo><mn>14</mn></mrow></msup></mrow></math>), consistent with standard floating-point precision. The software also maintained numerical agreement between implementations for the examined non-stationary physiological time-series. The platform provides a benchmarked implementation of the established single-component cosinor analysis, including confidence interval estimation for MESOR and amplitude based on the Student's <math><mi>t</mi></math>-distribution. Acrophase is reported as a point estimate without an uncertainty interval. It additionally integrates an ancillary Generalised Lomb-Scargle periodogram as a preliminary exploratory tool for empirical identification of a suitable period (<math><mi>T</mi></math>) prior to parametric cosinor analysis, together with interactive polar plot visualisation for phase-amplitude assessment. In summary, CosinorOnline provides an accurate, freely accessible, and reproducible resource for analysing biological time-series data without requiring programming expertise.</p>","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"1-14"},"PeriodicalIF":2.5,"publicationDate":"2026-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148812435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}