Chronobiology International最新文献

{"title":"Validating an Arabic translation of the Sleep, Circadian Rhythms, and Mood (SCRAM) questionnaire.","authors":"Hessa Abdulla Bugahoos, Ameena Duaij Albinjasim, Yasmin AlMashouk, Abdulmajeed Abdullah Alghamdi, Achraf Ammar, Hadeel Ghazzawi, Khaled Trabelsi, Jamie Byrne, Michael V Vitiello, Haitham Jahrami","doi":"10.1080/07420528.2025.2510501","DOIUrl":"10.1080/07420528.2025.2510501","url":null,"abstract":"<p><p>This study translated the Sleep, Circadian Rhythms, and Mood (SCRAM) questionnaire into Arabic and evaluated the psychometric properties and conceptual validity of the Arabic version. This process involved forward translation, back-translation, research team review, and pretesting of the Arabic SCRAM. A sample of 649 adults completed the Arabic SCRAM along with validation measures of sleep disturbances (Jenkins Sleep Scale: JSS) and depression severity (Patient Health Questionnaire: PHQ-9). Psychometric analyses included descriptive statistics, reliability analysis, test re-test, confirmatory factor analysis, and tests of convergent validity. The sample (77% female, mean age 26.31 years, range 18-47 years) demonstrated normal score distributions and adequate reliability on the Arabic SCRAM subscales. A three-factor structure was confirmed, aligning with the original English version. The Good Sleep and Depressed Mood subscales showed good convergence with the JSS and PHQ-9 scores, respectively. The Morningness subscale was not tested in the present research for convergent validity against other measures. The results provide preliminary support for a three-factor structure of the Arabic version of the SCRAM, with improved reliability indices (McDonald's <i>ω</i> ≈ 0.70) after removing three culturally non-optimal items; further validation is recommended before confirming these modifications.</p>","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"795-807"},"PeriodicalIF":2.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144157156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chronotype and sleep disturbances: A comparative analysis of sluggish cognitive tempo and attention deficit hyperactivity disorder.","authors":"Yadigar Düğüncü Terlemez, Nagihan Cevher Binici, Ali Evren Tufan, Çisel Yazan Songür, Fatma Sibel Durak","doi":"10.1080/07420528.2025.2509625","DOIUrl":"10.1080/07420528.2025.2509625","url":null,"abstract":"<p><p>Recent investigations into Sluggish Cognitive Tempo (SCT), also known as Cognitive Disengagement Syndrome, have primarily focused on its association with ADHD. However, emerging evidence suggests SCT may be a distinct clinical entity, despite frequent co-occurrence with ADHD symptomatology. While ADHD studies have elucidated sleep patterns and chronotype preferences, SCT research has largely focused on ADHD-comorbid cases, providing limited data on community-based adolescents and adults. This study aims to investigate sleep disturbances and chronotype characteristics in individuals with pure SCT compared to those with ADHD and healthy controls within a clinical sample. We utilized the DSM-IV-based Disruptive Behavior Disorders Rating Scale (DBDRS-parent and teacher form), Barkley Sluggish Cognitive Tempo Scale (BSCTS), the Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime Version (K-SADS), Children's Sleep Habit Questionnaire, and Children's Chronotype Questionnaire for the evaluation of children with SCT, ADHD, and healthy controls. Our findings revealed shorter sleep duration in ADHD (n: 67) children compared to both SCT (n: 50) and healthy controls (n: 50), with no significant difference between SCT and healthy controls (<i>p</i> < 0.001). Eveningness tendencies were highest in SCT but also elevated in ADHD compared to controls (<i>p</i> < 0.001). Additionally, daytime sleepiness was highest in SCT and higher in ADHD than controls (<i>p</i> < 0.001). Regression analyses demonstrated that SCT severity predicted both daytime sleepiness and eveningness.</p>","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"716-723"},"PeriodicalIF":2.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144141868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating effects of moderate hyperthermia at two phases of the circadian cycle for core temperature (heat gain and peak), on quadriceps maximal voluntary contraction force.","authors":"Ben J Edwards, Kevin P Gibbins, Chris J Morgan, Magali Giacomoni, Colin M Robertson, David A Low, Samuel A Pullinger","doi":"10.1080/07420528.2025.2494631","DOIUrl":"10.1080/07420528.2025.2494631","url":null,"abstract":"&lt;p&gt;&lt;p&gt;Athletes often perceive a performance disadvantage in the morning, in part, because of a recognised deficit in functional muscle force capacity. This diurnal variation in muscle force production has been attributed to higher rectal (T&lt;sub&gt;rec&lt;/sub&gt;) and muscle (T&lt;sub&gt;m&lt;/sub&gt;) temperatures in the evening as well as motivational, peripheral, and central factors. A warm-up is an essential component of sporting performance, however moderate hyperthermia reduces sporting gross muscular performance although possibly to a lesser degree in the morning (raising phase) than the peak of the core temperature rhythm (~17:00 h). We investigated whether i) increasing morning T&lt;sub&gt;rec&lt;/sub&gt; temperatures to evening resting values by an active warm-up leads to quadriceps muscle force production becoming equal to evening values. Or ii) raising T&lt;sub&gt;rec&lt;/sub&gt; passively in the morning or evening to 38.5°C results in greater quadriceps muscle force production reductions in the evening. Eight active males (mean±SD: age, 25.5 ± 1.9 yrs; body mass, 71.0 ± 6.7 kg; height, 1.79 ± 0.06 m) volunteered and randomly completed five sessions (separated by &gt; 48 h): control morning (M, 07:30 h) and evening (E, 17:30 h) sessions (both with an active 5-min warm-up) and three further trials - an active warm-up 07:30 h trial (M&lt;sub&gt;E&lt;/sub&gt;, until resting evening temperatures were reached), a morning (M&lt;sub&gt;38.5&lt;/sub&gt;) and an evening (E&lt;sub&gt;38.5&lt;/sub&gt;) passive warm-up trial which continued until T&lt;sub&gt;rec&lt;/sub&gt; values reached 38.5°C (immersed in a water-bath @ ~40°C, 45-50% Relative humidity). During each trial, 5-measures of maximal voluntary contraction (MVC) of the quadriceps on an isometric dynamometer (utilizing the twitch-interpolation technique) were performed with force (peak and mean of the 5-trials) and percentage activation recorded. T&lt;sub&gt;rec&lt;/sub&gt;, ratings of perceived exertion (RPE) and thermal comfort (TC) were measured. Measurements were made after the participants had reclined for 30-min at the start of the protocol and after the warm-ups/passive heating and prior to the measures for isometric dynamometry. T&lt;sub&gt;rec&lt;/sub&gt; and T&lt;sub&gt;m&lt;/sub&gt; (at 3, 2 and 1 cm depths) temperatures were taken at rest, after the passive warm-up, and immediately before the isometric MVC measurements. Data were analysed by general linear models with repeated measures. Isometric force for knee extension showed higher values in the evening than morning (peak Δ83.2 N, mean Δ67.8 N; &lt;i&gt;p&lt;/i&gt; &lt; 0.05). T&lt;sub&gt;rec&lt;/sub&gt; and T&lt;sub&gt;m&lt;/sub&gt; (at 3 cm depth) values were higher at rest in the evening than the morning (by 0.47 and 0.85°C respectively; &lt;i&gt;p&lt;/i&gt; &lt; 0.05) increasing from rest by 0.54 and 2.2°C, 1.78 and 2.2°C, and 1.31 and 1.8°C, in the M&lt;sub&gt;E,&lt;/sub&gt; M&lt;sub&gt;38.5&lt;/sub&gt; and E&lt;sub&gt;38.5&lt;/sub&gt; conditions, respectively; ratings of thermal comfort reflecting this (&lt;i&gt;p&lt;/i&gt; &lt; 0.05). There was no significant effect of active M&lt;sub&gt;E&lt;/sub&gt; warm-up and moderate hyperthermia M&lt;sub&gt;38.5&lt;/sub&gt; compar","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"622-639"},"PeriodicalIF":2.2,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143993266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dispositional mindfulness as a protective factor: Longitudinal effects on the relationship between morningness-eveningness, affective functioning, and depressive and anxiety symptoms.","authors":"Joanna Gorgol-Waleriańczyk","doi":"10.1080/07420528.2025.2491712","DOIUrl":"10.1080/07420528.2025.2491712","url":null,"abstract":"<p><p>Multiple research shows that morningness-eveningness is associated with affective functioning. Specifically, eveningness is associated with lower positive affect, higher negative affect, and higher mental health problems, while morningness shows the opposite correlation. Previous research indicated how the negative consequences of eveningness may be modified by individuals' psychological characteristics, such as personality and temperamental traits, or religiosity. Additionally, research indicated that dispositional mindfulness may act as a protective factor against higher depressive and anxiety symptoms among evening types. The present study explores the longitudinal effects of dispositional mindfulness on these relationships, extending the investigation to examine its impact on positive and negative affect. The study was conducted on a group of 660 individuals (319 women and 341 men) aged 19-55 (<i>M</i> ± <i>SD</i>: 38.08 ± 9.60), with data collected annually. The results showed that eveningness is associated with higher depressive and anxiety symptoms, as well as negative affect, and lower mindfulness and positive affect. Furthermore, the findings indicated that higher dispositional mindfulness moderated the link between eveningness and depressive and anxiety symptoms, as well as negative affect, over one year. However, this moderation effect did not extend to a positive affect. These results suggest that engaging in mindfulness practices to cultivate and strengthen mindfulness may be beneficial as a supplementary approach in the therapeutic process for evening types. Additionally, the results provide the first evidence of a longitudinal effect of dispositional mindfulness on the relationship between morningness-eveningness and features of mental health and affect.</p>","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"610-621"},"PeriodicalIF":2.2,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143955364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Self-reported and actimetry-based cluster analysis of mood rhythmicity profiles in adolescents with and at risk for Major Depressive Disorder.","authors":"Guilherme Amando, Nicóli B Xavier, Rogério Boff Borges, Manuela Silva Silveira da Mota, Rivka Pereira, Pedro Henrique Manfro, Fernanda Rohrsetzer, Jader Piccin, Laila Souza, Adile Nexha, André Comiran Tonon, Christian Kieling, Maria Paz L Hidalgo","doi":"10.1080/07420528.2025.2496345","DOIUrl":"10.1080/07420528.2025.2496345","url":null,"abstract":"<p><p>Greater self-perceived rhythmicity of mood-related symptoms and behaviors has been associated with depressive symptoms in the general public. We aimed to evaluate differences in adolescents at risk for or with a diagnosis of major depressive disorder (MDD) regarding perception of symptom rhythmicity and actimetry parameters. In this cross-sectional study, 96 adolescents were stratified into three groups based on either a diagnosis of MDD or on a composite score for the risk of developing depression: MDD, high risk (HR), and low risk (LR). Participants completed questionnaires regarding depressive symptoms (Mood and Feelings Questionnaire for adolescents) and self-perceived mood rhythmicity (Mood Rhythm Instrument for Youth - MRhI-Y). Actimetry data were collected for 10 continuous days and Non-Parametric Circadian Rhythm Analyses were performed. The MDD group reported higher MRhI-Y total scores, particularly in affective symptoms compared to both other groups. In spite of actimetry variables that did not correlate with MRhI-Y total scores, cluster analysis using MRhI-Y and actimetry revealed three distinct profiles corresponding to all groups. Identifying rhythmicity in mood-related behaviors in adolescents may help distinguish different groups at-risk for MDD and in a current depressive episode. Understanding these patterns could inform early interventions, potentially preventing the onset of the disorder in susceptible individuals.</p>","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"640-652"},"PeriodicalIF":2.2,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143966080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between chronotype, sleep quality, and smartphone addiction in health sciences students in Morocco and Spain.","authors":"Ali Allouch, Fadila Bousgheiri, Karima Sammoud, Rut Navarro-Martínez, Vanessa Ibáñez Del Valle, Adil Najdi, Omar Cauli, Meftaha Senhaji, Nisrin El Mlili","doi":"10.1080/07420528.2025.2494633","DOIUrl":"10.1080/07420528.2025.2494633","url":null,"abstract":"<p><p>Poor sleep quality can cause various health problems. Despite this evidence, much research demonstrates significant heterogeneity in the amounts that people sleep across cultures. This suggests that despite serving fundamental biological functions, sleep is also subject to cultural influence. Variations in chronotype and problematic smartphone use influence sleep quality, and both poor sleep and smartphone addiction can result in poor health and academic performance. This study aimed to measure the associations between chronotype, sleep quality, and smartphone addiction in a population of 1210 health sciences university students in Morocco and Spain. The Horne and Ostberg Morningness-Eveningness Questionnaire, Pittsburgh Sleep Quality Index, and Smartphone Addiction Scale were used to assess the study variables. The study found that the majority of students belonged to the \"Neutral\" chronotype (73.9%), that the prevalence of smartphone addiction was fairly high (46.3%), and that the prevalence of poor sleep quality was high (74.0%). Associations were found between chronotype and smartphone addiction (<i>p</i> < 0.001), subjective sleep quality (<i>p</i> = 0.006), sleep duration (<i>p</i> = 0.005), sleep disturbances (<i>p</i> = 0.013), and use of sleep medications (<i>p</i> = 0.003). Chronotype was also associated with gender (<i>p</i> = 0.009), country of study (<i>p</i> < 0.001), field of study (<i>p</i> < 0.001), and chronic health problems (<i>p</i> = 0.001). Associations between chronotype and field of study (<i>p</i> < 0.001 for the evening chronotype), sleep disturbance (<i>p</i> < 0.001 and <i>p</i> = 0.026 for both the evening and morning chronotypes), and smartphone addiction (<i>p</i> < 0.001 for the morning chronotype) were confirmed in the multivariate analysis. Our study highlights associations with chronotype that affect sleep quality and addictive behavior when young health sciences students use smartphones. This implies the need to teach or develop strategies to prevent or minimize the negative consequences of the chronotype on mental health and its effects on production. Educational activities on sleep hygiene strategies, the healthy use of smartphones taking into account the chronotype in health sciences students, are needed in order to benefit mental health offuture healthcare professionals.</p>","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"595-609"},"PeriodicalIF":2.2,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143986751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A modified at-home methodology for measuring dim light melatonin onset timing in healthy adults.","authors":"Chris Xie Chen, Ran Wang, Forrest Tin Wai Cheung, Amy Wing Yin Ho, Chung Shun Ho, Ngan Yin Chan, Joey Wing Yan Chan, Wai Kai Hou, Suk-Yu Yau, Yan Liu, Tatia Mei Chun Lee, Shirley Xin Li, Yun Kwok Wing","doi":"10.1080/07420528.2025.2500404","DOIUrl":"10.1080/07420528.2025.2500404","url":null,"abstract":"<p><p>The goal of this study was to investigate whether a modified at-home dim light melatonin onset (DLMO) assessment would be comparable to the in-laboratory DLMO assessment. Fifty-five participants underwent the at-home DLMO, while 55 age- and sex-matched participants underwent the in-laboratory DLMO assessment. Each participant underwent 14 d of actigraphy monitoring with sleep diary, one overnight polysomnography (PSG), followed by another night for DLMO assessment, either in the laboratory or at home. The at-home DLMO and the in-laboratory DLMO were correlated to chronotype and habitual sleep wake time. DLMOs, compliance with the sampling time and dim lighting were compared between the two groups. The DLMOs were similar between at-home and in-laboratory assessments (Absolute threshold: 22:14 h at home and 22:30 h at in-laboratory, <i>p</i> = 0.18; Relative threshold: 21:42 h at home and 22:19 h at in-laboratory, <i>p</i> = 0.17). The earlier at-home DLMO and earlier in-laboratory DLMO were both moderately correlated to earlier chronotype and earlier sleep wake time. The compliance with the scheduled sampling time was slightly lower than that in the laboratory, while the compliance with dim lighting was comparable between the at-home group and the in-laboratory group. Our modified at-home assessment of DLMO is a feasible and valid alternative to the in-laboratory assessment.</p>","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"653-663"},"PeriodicalIF":2.2,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143971447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Melatonin partially restores hepatic nocturnin oscillations in experimental models of MASLD.","authors":"Shruti Kulshrestha, Rhydham Karnik, Aliasgar Vohra, Apeksha Joshi, Ranjitsinh Devkar","doi":"10.1080/07420528.2025.2496347","DOIUrl":"10.1080/07420528.2025.2496347","url":null,"abstract":"<p><p>Melatonin, a pleiotropic neurohormone, is recognized for its hepatoprotective role in metabolic dysfunction-associated steatotic liver disease (MASLD) triggered by diet and/or chronodisruption. Nocturnin (Noct), a circadian clock output regulating hepatic lipid metabolism, has an unclear role in MASLD. This study explores circadian oscillations of Noct in MASLD and its synergy with melatonin. Differential gene expression analysis identified key lipogenic genes (HNF-4A and SCD) as targets of Noct enzymatic activity. Male C57BL/6J mice were subjected to high-fat-high-fructose (H) diet with or without chronodisruption (CD) for 16 weeks. Noct mRNA peaked at ZT12 in Control and H groups, while CD and HCD groups showed peaks at ZT6, alongside increased % relative amplitude, cumulative expression, and shifted Centre of Gravity (CoG). Melatonin treatment in H, CD, and HCD groups significantly reduced Noct amplitude and cumulative expression. In OA-treated HepG2 cells, Noct mRNA and protein levels rose at 36 h and 32 h, respectively, with CoG shifts. Melatonin reduced Noct mRNA but increased protein levels while correcting rhythmicity. Collectively, MASLD induces elevation and phase shifts in hepatic Noct expression, and melatonin demonstrates corrective effects on Noct circadian phasing, underscoring its therapeutic potential.   .</p>","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"664-677"},"PeriodicalIF":2.2,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143986722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epigenetic markers of adverse lifestyle identified among evening and night shift workers in two UK population-based studies: Generation Scotland and Understanding Society.","authors":"Paige M Hulls, Daniel L McCartney, Yanchun Bao, Rosie M Walker, Frank de Vocht, Richard M Martin, Caroline L Relton, Kathryn L Evans, Meena Kumari, Riccardo E Marioni, Rebecca C Richmond","doi":"10.1080/07420528.2025.2493208","DOIUrl":"10.1080/07420528.2025.2493208","url":null,"abstract":"<p><p>Epigenetic changes in the form of DNA methylation (DNAm) may act as biological markers of risk factors or adverse health states. In two cohort studies, Generation Scotland (GS) (<i>n</i> = 7,028) and Understanding Society (UKHLS) (<i>n</i> = 1,175), we evaluated associations between evening or night shift work and four lifestyle factors (body mass index, smoking, alcohol, education) through linear regression using both conventionally measured phenotypes and DNA methylation-based scores proxying the phenotypes. DNA methylation-based measures of biological ageing were also generated using six established \"epigenetic clocks.\" Meta-analysis of GS and UKHLS results was conducted using inverse-variance weighted fixed effects. Evening/night shift work was associated with higher BMI (0.79; 95%CI 0.02, 1.56; <i>p</i> = 0.04) and lower education ( - 0.18;  - 0.30,  - 0.07; <i>p</i> = 0.002). There was weak evidence of association between evening/night shift work and DNAm scores for smoking (0.06,  - 0.03, 0.15; <i>p</i> = 0.18) and education ( - 0.24;  - 0.49, 0.01; <i>p</i> = 0.06) in fully adjusted models (adjusted for age, sex, methylation principal components and phenotypic measures). Two of the epigenetic age measures demonstrated higher age acceleration among evening/night shift workers (0.80; 0.42, 1.18; <i>p</i> < 0.001 for GrimAge and 0.46; 0.00, 0.92; <i>p</i> = 0.05 for PhenoAge). In over 8,000 participants from two cohort studies, evening/night shift work was associated with both phenotypic and DNA methylation-based measures of higher BMI and lower education. DNAm predictors of smoking and ageing were also related to evening/night shift work. Epigenetic measures may provide insights into the health and lifestyle profiles of night shift workers.</p>","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"561-571"},"PeriodicalIF":2.2,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143955151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of chronotype characteristics on cardiovascular health behaviors in school-age children: A cross-sectional study.","authors":"Gamzegül Altay, Mehtap Metin Karaaslan","doi":"10.1080/07420528.2025.2493218","DOIUrl":"10.1080/07420528.2025.2493218","url":null,"abstract":"<p><p>This study aimed to investigate the effect of chronotype characteristics on cardiovascular health behaviors in school-age children. This descriptive, correlational, and cross-sectional study involved 424 school-age children aged 10-12. Participants completed the Morningness-Eveningness Scale for Children (MESC) and the Cardiovascular Health Behavior Scale for Children (CHBSC). The results were analyzed using descriptive statistics and multivariate regression analysis, adhering to ethical principles throughout the study. The mean MESC and CHBSC scores for the children were 28.37 ± 5.20 and 57.04 ± 11.34, respectively. 53.8% of the children exhibited moderate cardiovascular health behaviors, while 79% had a moderate chronotype. A moderate negative correlation was observed between MESC and CHBSC scores (<i>r</i> = -0.39, <i>p</i> < 0.01), with the MESC explaining 16% of the variance in cardiovascular health behaviors. The MESC influenced cardiovascular health behaviors and its subscales nutrition, exercise, sedentary lifestyle, self-love, and stress subscales. Most school-age children display intermediate chronotype characteristics and cardiovascular health behaviors. Children with an evening chronotype demonstrated lower levels of cardiovascular health behaviors. Chronotype characteristics had the most negative impact on the sedentary lifestyle aspect of cardiovascular health behaviors. Furthermore, chronotype plays a significant role in explaining the key factors influencing cardiovascular health behaviors.</p>","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"572-580"},"PeriodicalIF":2.2,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143983459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}