Chronobiology International最新文献_第2页

Rhythm in the vertical distribution of Danio rerio under photic and magnetic zeitgebers. 光、磁两种授时基因对达尼奥垂直分布的影响。

IF 1.7 4区医学

Chronobiology International Pub Date : 2026-05-01 Epub Date: 2026-01-27 DOI: 10.1080/07420528.2026.2621243

Elena Osipova, Natalia Pankova, Vera Pavlova, Daniil Sizov, Svetlana Zhdanova, Artem Dushko, Evgeny Izvekov, Viacheslav V Krylov

{"title":"Rhythm in the vertical distribution of Danio rerio under photic and magnetic zeitgebers.","authors":"Elena Osipova, Natalia Pankova, Vera Pavlova, Daniil Sizov, Svetlana Zhdanova, Artem Dushko, Evgeny Izvekov, Viacheslav V Krylov","doi":"10.1080/07420528.2026.2621243","DOIUrl":"10.1080/07420528.2026.2621243","url":null,"abstract":"Circadian rhythms in the vertical distribution of adult zebrafish and their potential sensitivity to geomagnetic fluctuations remain poorly characterized. In this study, we investigated Danio rerio maintained under different light-dark regimes and exposed to natural diurnal geomagnetic variation (~30 nT, with a 24-h period) or slow magnetic oscillations (~100-150 nT, with periods of 26.8, 33.76, or 36 h). Behavioral endpoints included the proportion of time spent in the upper versus lower part of the water column and the frequency of midline crossings. Under standard and modified light-dark cycles, zebrafish exhibited a robust rhythm, occupying upper layers during darkness and shifting downward during the light phase. This pattern differs from that described for zebrafish in natural environments and probably reflects long-term adaptation to aquaculture. Under constant illumination, free-running rhythms with periods close to 24 h persisted across groups. Analysis of midline crossing frequency revealed a significant ~33.8 h rhythm in fish pre-exposed to the atypical 24:12 h light-dark cycle, consistent with the periodicity of the applied magnetic oscillation. These results suggest that geomagnetic fluctuations may function as an extremely weak zeitgeber compared to the dominant influence of the photoperiod. Prior exposure to an atypical light-dark regime, which may have reset the biochemical processes sustaining the endogenous oscillators, appears to be required for the manifestation of magnetically driven rhythm entrainment.","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"664-675"},"PeriodicalIF":1.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146060710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Meal timing and ghrelin: A chrononutritional perspective on weight regulation potential. 进餐时间和胃饥饿素：从时间营养角度看体重调节潜力。

IF 1.7 4区医学

Chronobiology International Pub Date : 2026-05-01 Epub Date: 2026-02-01 DOI: 10.1080/07420528.2026.2624753

Fathiyyatul Khaira, Delmi Sulastri

{"title":"Meal timing and ghrelin: A chrononutritional perspective on weight regulation potential.","authors":"Fathiyyatul Khaira, Delmi Sulastri","doi":"10.1080/07420528.2026.2624753","DOIUrl":"10.1080/07420528.2026.2624753","url":null,"abstract":"Ghrelin is a peptide hormone that plays a central role in short-term appetite regulation and energy balance. Its secretion is not only influenced by nutritional status but also shaped by circadian rhythms and habitual eating patterns. Ghrelin levels typically rise during fasting and decrease after meals, but they also follow a daily rhythm, peaking during the night and reaching their lowest levels in the morning. Human studies suggest that consistent meal schedules may entrain ghrelin secretion, with anticipatory rises occurring before habitual mealtimes. Experimental interventions show that morning-loaded eating patterns, compared to evening-loaded ones, lead to stronger postprandial ghrelin suppression, enhanced satiety hormone responses, and greater weight loss, even with similar caloric intake. In contrast, delayed or misaligned eating, such as during night-shift work, is associated with elevated ghrelin levels at biologically inappropriate times and increased hunger. Some studies have also highlighted the leptin-to-ghrelin ratio as a useful marker of appetite regulation and metabolic risk, particularly in overweight individuals. Together, these findings support the idea that the timing of food intake modulates ghrelin dynamics and influences metabolic outcomes. Meal timing, when aligned with endogenous biological rhythms, may therefore serve as a practical target for chrononutritional strategies aimed at improving appetite control and weight regulation.","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"606-613"},"PeriodicalIF":1.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146099821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The menstrual clock, an open access tool to identify and illustrate menstrual phases, windows, and events. 月经时钟，一个开放的工具来识别和说明月经阶段，窗口和事件。

IF 1.7 4区医学

Chronobiology International Pub Date : 2026-05-01 Epub Date: 2026-02-16 DOI: 10.1080/07420528.2025.2600571

Marie Gombert Labedens, Fiona C Baker

{"title":"The menstrual clock, an open access tool to identify and illustrate menstrual phases, windows, and events.","authors":"Marie Gombert Labedens, Fiona C Baker","doi":"10.1080/07420528.2025.2600571","DOIUrl":"10.1080/07420528.2025.2600571","url":null,"abstract":"The menstrual cycle is a biological rhythm, the effects of which are challenging to investigate due to important variability in cycle characteristics, including cycle duration, both between and within individuals. Here, we introduce a tool that calculates this variability, identifies menstrual phases and even more granular menstrual windows, and enables an efficient illustration of results on a circular plot, or menstrual clock. A degree angle approach is used, graduating the follicular phase (menses to ovulation) from 0° to 180° and the luteal phase (ovulation to next menses) from 180° to 360°. This approach enables comparisons between cycles of different duration and the visualization of the distribution of events (symptoms or treatment) and variation of levels (temperature, metabolites, secondary effects, etc.) across the cycle. The open access MenstrualClock R package, incorporating this method in four functions, has been created to facilitate its implementation in research. By calculating menstrual cycle angles, the menstrual clock method provides a convenient tool that can be used to standardize and visualize menstrual cycle phase. Future studies can test the tool against hormone profiles and develop it further to advance research about menstrual cycle effects.","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"589-594"},"PeriodicalIF":1.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146200283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chronotype and physical activity associations with fluid and dietary habits in young adults. 年轻人的睡眠类型和身体活动与饮水和饮食习惯的关系

IF 1.7 4区医学

Chronobiology International Pub Date : 2026-05-01 Epub Date: 2026-01-25 DOI: 10.1080/07420528.2026.2619014

Hilal Ertürk Yaşar

{"title":"Chronotype and physical activity associations with fluid and dietary habits in young adults.","authors":"Hilal Ertürk Yaşar","doi":"10.1080/07420528.2026.2619014","DOIUrl":"10.1080/07420528.2026.2619014","url":null,"abstract":"This study investigated the relationships between chronotype, physical activity, and fluid and nutrient intake in healthy young adults. A total of 935 participants (66.6% female), aged 18-30, were classified into morning, intermediate, or evening chronotypes using the Morningness - Eveningness Questionnaire. Physical activity was categorized as active or sedentary based on self-reported exercise frequency and duration. Nutrient intake was measured using 24-h dietary recall, a Food Frequency Questionnaire, and a structured fluid intake survey. Data collection occurred in June and July to minimize seasonal effects. Physically active individuals consumed significantly more water daily than sedentary participants (p < 0.001, η2 = .088). They also reported higher intake of black tea, herbal tea, iced tea, Turkish coffee, and milk (all p < 0.001). Evening chronotype individuals consumed significantly less black tea and milk (both p < 0.001) but showed no significant difference in water intake (p = 0.088). Evening types were also linked to lower consumption of red meat (B = -0.38, p = 0.034) and fish (B = -0.58, p = 0.002), while the decrease in egg consumption was not statistically significant (p = 0.082). These results suggest that morning chronotype and physical activity correlate with healthier fluid intake patterns, whereas evening chronotype may reduce intake of some animal proteins. Overall, hydration and diet appear influenced by lifestyle and biological rhythms. The study highlights the need for personalized nutrition counseling that considers chronotype and physical activity to promote healthier behaviors.","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"634-645"},"PeriodicalIF":1.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146046198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Longitudinal study of light exposure, sleep, rest-activity rhythms, alertness and cognitive function among adults with stable heart failure. 稳定性心力衰竭成人的光照、睡眠、休息-活动节律、警觉性和认知功能的纵向研究。

IF 1.7 4区医学

Chronobiology International Pub Date : 2026-05-01 Epub Date: 2026-02-09 DOI: 10.1080/07420528.2026.2623046

Sangchoon Jeon, Zequan Wang, Samantha Conley, Kelley Lafleur, Nancy S Redeker

{"title":"Longitudinal study of light exposure, sleep, rest-activity rhythms, alertness and cognitive function among adults with stable heart failure.","authors":"Sangchoon Jeon, Zequan Wang, Samantha Conley, Kelley Lafleur, Nancy S Redeker","doi":"10.1080/07420528.2026.2623046","DOIUrl":"10.1080/07420528.2026.2623046","url":null,"abstract":"We evaluated the associations between daily light and sleep and rest-activity characteristics, alertness, and cognition over 1 year among participants in a study of the effects of cognitive behavioral therapy for insomnia heart failure [N = 168 participants (Mean age = 63.2 + 12.7 y; n = 72/42% women; left ventricular ejection fraction <45% = 57 (34.3%))]. We measured sleep, rest-activity rhythms, the day-to-nighttime light exposure ratio (AUC), light time above threshold (TAT), the mean timing of light above threshold (MLiT), the phase difference, and the light regularity index (LRI) using wrist actigraphy at baseline and 3, 6, and 12 months post-intervention. We used the Insomnia Severity Index, the Pittsburgh Sleep Quality Index, the PROMIS Cognitive Abilities Scale, the Psychomotor Vigilance Test, and adjusted and unadjusted general linear models. Daytime light exceeding 100 lux was associated with a later sleep midpoint, a higher circadian quotient, less intra-daily variability, and greater inter-daily stability of rest-activity rhythms. Light levels above 100 lux were associated with fewer PVT lapses, and higher AUC values with better cognitive ability (all p < 0.05). The phase difference was associated with insomnia, poorer sleep quality, and cognitive impairment over 12 months. Light levels and variability were not related to self-reported sleepiness, sleep quality, or insomnia symptoms.","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"681-693"},"PeriodicalIF":1.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146141188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cross-sectional associations of sleep timing and eating behavior factors with migraine in a predominantly female adult sample. 睡眠时间和饮食行为因素与偏头痛在一个主要的女性成人样本的横断面关联。

IF 1.7 4区医学

Chronobiology International Pub Date : 2026-05-01 Epub Date: 2026-02-02 DOI: 10.1080/07420528.2026.2620509

Shannon Richardson, Andrew N Coogan, Unai Diaz-Orueta

{"title":"Cross-sectional associations of sleep timing and eating behavior factors with migraine in a predominantly female adult sample.","authors":"Shannon Richardson, Andrew N Coogan, Unai Diaz-Orueta","doi":"10.1080/07420528.2026.2620509","DOIUrl":"10.1080/07420528.2026.2620509","url":null,"abstract":"This exploratory study aimed to better ascertain specific features of sleep and eating behaviors associated with migraine. A cross-sectional case-control approach was used with an online convenience sample; 86 individuals with migraine and 74 non-migraine individuals (mean age = 44 y.o., 90% female) were recruited via social media and university students in Ireland/UK between July 2023 and July 2024. Migraine status was determined by self-report of prior diagnosis by a health-care practitioner; no ICHD-3 interviews were performed. Individuals with migraine showed significantly lower self-regulation (2.95 ± .04 vs 3.17 ± .09, d = .45), reduced food fussiness (3.04 ± .08 vs. 2.4 ± .10, d = .84), and increased hunger (3.30 ± .08 vs. 3.00 ± .08, d = -.41). Both workdays (7:36 h ± 0:09 h vs. 6:57 h ± 0:09 h, d = -.52) and weekly average sleep duration (7:19 h ± 0:09 h vs. 7:44 h ± 0:08 h, d = -0.34) was significantly longer in individuals with migraine. Non-adjusted logistic regression analysis revealed that longer workday sleep duration (OR = .1.69 (95% CI = 1.12, -2.55), p = 0.013) was associated with increased odds of a migraine diagnosis; while greater self-regulation of eating (OR = 0.28, 95% CI (0.092, 0.88), p = 0.028) and greater food fussiness were associated with reduced odds of a migraine diagnosis (OR = 0.29, 95% CI (0.154, 0.54), p < 0.001). Additional intragroup results for individuals with migraine are also presented.","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"646-655"},"PeriodicalIF":1.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146104389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Serial homicide offenders and the lunar cycle. 连环杀人案罪犯和月亮周期。

IF 1.7 4区医学

Chronobiology International Pub Date : 2026-05-01 Epub Date: 2026-02-16 DOI: 10.1080/07420528.2025.2606282

Daniel Salafranca Barreda, Jonatan A González

{"title":"Serial homicide offenders and the lunar cycle.","authors":"Daniel Salafranca Barreda, Jonatan A González","doi":"10.1080/07420528.2025.2606282","DOIUrl":"10.1080/07420528.2025.2606282","url":null,"abstract":"The purpose of this research is to establish whether there are factors that contribute to the predatory activation of serial homicide offenders (SHOs) in relation to the lunar cycles. In order to move the discussion away from the media fascination with SHOs and the perpetuation of myths regarding the lunar cycle, we used a quasi-Poisson log-linear regression model based on 9976 homicides that occurred between 1 January 1960 and 30 November 2016. The results indicate that lunar phase does not influence the frequency of homicides (p = 0.997), with rate ratios across Moon phases ranging narrowly around 1.00 (e.g., full moon RR = 1.03; 95% CI: 0.66-1.63). Likewise, other variables related to the lunar cycle, such as the Moon´s distance from Earth, seasonal variation, and the percentage of the Moon´s illuminated surface, were not statistically significant predictors of homicide. In contrast, the age of the victims showed a strong and significant relationship, with persons aged 15-64 being 8.71 times more likely to be homicide victims than others (p < 2e-16). In general, these findings, obtained over a 56-year observation period, provide no statistical evidence of a relationship between the lunar cycle and SHO criminal activity. The large sample size and extended temporal coverage enhance the generalizability of these conclusions.","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"623-633"},"PeriodicalIF":1.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146200257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Addendum. 附录。

IF 1.7 4区医学

Chronobiology International Pub Date : 2026-05-01 Epub Date: 2026-02-23 DOI: 10.1080/07420528.2026.2635244

引用次数: 0

Intestinal production of melatonin and its putative role as a circadian organizer. 肠道褪黑激素的产生及其作为昼夜节律组织者的假定作用。

IF 1.7 4区医学

Chronobiology International Pub Date : 2026-05-01 Epub Date: 2026-03-06 DOI: 10.1080/07420528.2025.2574851

Cecilia González, Dulce Andrade-Pavón, Claudia Alva-Sánchez, Iván Villanueva

{"title":"Intestinal production of melatonin and its putative role as a circadian organizer.","authors":"Cecilia González, Dulce Andrade-Pavón, Claudia Alva-Sánchez, Iván Villanueva","doi":"10.1080/07420528.2025.2574851","DOIUrl":"10.1080/07420528.2025.2574851","url":null,"abstract":"Pineal melatonin is a potent synchronizer within the circadian system. Certain extra-pineal tissues also synthesize melatonin, including the gastrointestinal organs, whose melatonin contents can exceed that of pineal severalfold. Considering the role of pineal melatonin as a general synchronizer, we investigated whether the intestinal melatonin could serve a similar role in the local organization of the metabolic events, as a core element of the Food-Entrainable Oscillator (FEO). To be considered so, the intestinal secretory activity should meet some requirements: it should have self-sustained rhythmicity, that should also be synchronized to but not depend on feeding. To test this, we analyzed the circadian expression of the rate-limiting enzyme of melatonin synthesis, AANAT, in the intestine of rats. We found that AANAT expression varies along the intestine and shows a clear circadian pattern only in the proximal (duodenal) and distal (colonic) edges. The circadian variation in duodenum was abolished by fasting, implying that this activity is not self-sustained but reactive to feeding. The colon had the highest AANAT expression that was also rhythmic, but the phase of this rhythm was not synchronized to feeding. We propose that intestinal melatonin derives from different populations of secreting cells, but none of these populations meets the criteria for a pacemaker underlying the FEO.","PeriodicalId":10294,"journal":{"name":"Chronobiology International","volume":" ","pages":"614-622"},"PeriodicalIF":1.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147363594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sleep, circadian rhythms, and brain function in fish. 鱼类的睡眠、昼夜节律和大脑功能。

IF 1.7 4区医学

Chronobiology International Pub Date : 2026-05-01 Epub Date: 2026-02-06 DOI: 10.1080/07420528.2026.2624751

Ahmet Topal

引用次数: 0