Clinical and Translational Gastroenterology最新文献

{"title":"Nausea and Gastric Myoelectrical Activity Are Influenced by Hormonal Contraception in Chronic Gastroduodenal Disorders.","authors":"Alexandria H Lim, Chris Varghese, Gabrielle Sebaratnam, Gabriel Schamberg, Stefan Calder, Armen Gharibans, Christopher N Andrews, Charlotte Daker, Daphne Foong, Vincent Ho, Michelle R Wise, Gregory O'Grady","doi":"10.14309/ctg.0000000000000880","DOIUrl":"10.14309/ctg.0000000000000880","url":null,"abstract":"<p><strong>Introduction: </strong>Chronic gastroduodenal disorders are more prevalent among young women, many of whom are hormonal contraception users. We aimed to evaluate the effects of hormonal contraception on symptom severity and gastric myoelectrical activity in people with chronic gastroduodenal disorders.</p><p><strong>Methods: </strong>This analysis was conducted on a large international cohort of patients who met Rome IV criteria for chronic nausea and vomiting syndrome or functional dyspepsia and had undergone body surface gastric mapping using Gastric Alimetry. Symptoms were continuously reported on 0-10 Likert scales using a validated symptom logging app.</p><p><strong>Results: </strong>One hundred twenty-seven people were included: 43 women using hormonal contraception, 30 not using hormonal contraception, 30 postmenopausal women, and 24 men. Hormonal contraception users had higher nausea than nonusers (3.80 [interquartile range 2.00-5.42] vs 2.25 [0.20-4.43]; P < 0.05), particularly when using combined oral contraceptives with hormone-free intervals compared with continuous use (5.20 [4.30-6.00] vs 2.40 [1.70-3.80], P = 0.02). Premenopausal women were more symptomatic than postmenopausal women and men ( P < 0.001). Principal Gastric Frequency was higher in hormonal contraception users (median 3.1 cpm vs 3.00 cpm, P < 0.001) and highest with progestogen-only formulations ( P < 0.02).</p><p><strong>Discussion: </strong>Women with gastroduodenal disorders on hormonal contraception experience increased nausea in comparison with nonusers, with substantial variation dependent on contraceptive type. Hormonal contraception users also demonstrated modified gastric electrophysiology. These results imply that nonhormonal contraceptive alternatives should be trialled as a means to reduce symptoms in gastroduodenal disorders.</p>","PeriodicalId":10278,"journal":{"name":"Clinical and Translational Gastroenterology","volume":" ","pages":"e00880"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12456531/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144494883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rectal Neuroendocrine Tumors: Toward Translationally Informed Comparisons of ESD and TEM.","authors":"Shameer Tahir, Hamza Sajid","doi":"10.14309/ctg.0000000000000895","DOIUrl":"10.14309/ctg.0000000000000895","url":null,"abstract":"","PeriodicalId":10278,"journal":{"name":"Clinical and Translational Gastroenterology","volume":" ","pages":"e00895"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12456556/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145013993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: Deep Learning in High-Resolution Anoscopy: Assessing the Impact of Staining and Therapeutic Manipulation on Automated Detection of Anal Cancer Precursors.","authors":"Miguel Mascarenhas Saraiva, Lucas Spindler, Nadia Fathallah, Hélene Beaussier, Célia Mamma, Tiago Ribeiro, João Afonso, Mariana Carvalho, Rita Moura, Pedro Cardoso, Francisco Mendes, Miguel Martins, Julien Adam, João Ferreira, Guilherme Macedo, Vincent de Parades","doi":"10.14309/ctg.0000000000000894","DOIUrl":"10.14309/ctg.0000000000000894","url":null,"abstract":"","PeriodicalId":10278,"journal":{"name":"Clinical and Translational Gastroenterology","volume":" ","pages":"e00894"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12456483/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145022929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adherence to Multitarget Stool DNA Testing in Individuals Aged 45-49 Years With Average Risk for Colorectal Cancer.","authors":"Mallik Greene, Mark Camardo, A Burak Ozbay, Michael Dore, A Mark Fendrick, Paul Limburg","doi":"10.14309/ctg.0000000000000878","DOIUrl":"10.14309/ctg.0000000000000878","url":null,"abstract":"<p><strong>Introduction: </strong>Recommendations for colorectal cancer (CRC) screening have been updated to include individuals aged 45-49 years, addressing recent increases in CRC rates among young adults. The multitarget stool DNA (mt-sDNA) test is approved for average-risk individuals aged 45-49 years and is a noninvasive, at-home, stool-based option. This real-world study quantified mt-sDNA screening adherence rates for individuals aged 45-49 years.</p><p><strong>Methods: </strong>This was a retrospective analysis of individuals aged 45-49 years with average risk for CRC and no history of mt-sDNA testing. Individuals received an mt-sDNA test kit based on a point-of-care order. Adherence was defined as the return of a kit resulting in a valid test result within 1 year of prescription.</p><p><strong>Results: </strong>A total of 1,126,523 individuals were included. Most (58.6%) were female, and 62.2% received digital communications about the test through text message only. Overall, 68.9% returned their mt-sDNA kit within 1 year. Across provider types, adherence was highest for individuals who were prescribed the test by a gastroenterologist (75.5%); among payor types, adherence was highest for those enrolled in commercial insurance (70.9%). Adherence was lowest for individuals who did not receive any digital communications (54.9%) vs those who did. In a logistic regression analysis, digital communication and payor type were the strongest predictors of adherence.</p><p><strong>Discussion: </strong>In this large real-world study, 68.9% of individuals aged 45-49 years returned an mt-sDNA CRC screening test within 1 year. Increasing digital communication may improve mt-sDNA screening adherence.</p>","PeriodicalId":10278,"journal":{"name":"Clinical and Translational Gastroenterology","volume":" ","pages":"e00878"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12456591/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144494882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Single GNAS Droplet-Based Digital Polymerase Chain Reaction Analysis of Pancreatic Cyst Fluid: An Effective Up-Front Strategy for Mucinous Cyst Diagnosis by Endoscopic Ultrasound-Guided Fine-Needle Aspiration.","authors":"Isis K Araujo, Guillem Soy, Angels Ginès, Oriol Sendino, Glòria Fernández-Esparrach, Cristina Sánchez-Montes, Miriam Cuatrecasas, Ivan Archilla, Carla Montironi, Alós Silvia, Fabio Ausania, Manuel Domínguez-Fraile, Verónica Villagrasa, Mónica López-Guerra, Dolors Colomer, Eva C Vaquero","doi":"10.14309/ctg.0000000000000887","DOIUrl":"10.14309/ctg.0000000000000887","url":null,"abstract":"<p><strong>Introduction: </strong>Accurate diagnosis of mucinous pancreatic cystic neoplasms (mPCNs) remains a clinical challenge. This study investigated the utility of single GNAS droplet-based digital polymerase chain reaction (ddPCR) analysis as a novel approach to refine the diagnostic accuracy of mPCNs using endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA).</p><p><strong>Methods: </strong>Patients who underwent EUS-FNA and GNAS pancreatic cyst fluid (PCF) analyses for pancreatic cystic lesion (PCL) assessment were prospectively enrolled. Cysts were categorized as mPCNs, non-mPCNs, or inconclusive PCLs (iPCLs) by integrating increasing information levels: high-resolution imaging and non-DNA PCF features (level 1), GNAS PCF analysis (level 2), and surgical pathology (level 3).</p><p><strong>Results: </strong>One hundred forty patients were included, 25 of whom underwent pancreatic surgery. Level 1 identified 68 mPCNs (49%), 24 non-mPCNs (17%), and 48 iPCLs (34%). GNAS mutations were detected in 42 of 68 (62%) mPCNs, 1 of 24 (4%) non-mPCNs, and 16 of 48 (33%) iPCLs. Level 2 increased mPCN detection to 62% and reduced iPCLs by one-third. Mutated GNAS showed 66% sensitivity for diagnosing mPCNs in the whole cohort and 65% in resected cases, outperforming both imaging and non-DNA PCF mucinous criteria, with 100% specificity and limited concordance with carcinoembryonic antigen, cytology, and fluid viscosity, highlighting its complementary diagnostic value. Cost-effectiveness simulations for iPCLs demonstrated that GNAS -ddPCR significantly reduced diagnostic costs by 24% compared with next-generation sequencing testing.</p><p><strong>Discussion: </strong>Single GNAS- ddPCR analysis in PCF supported mPCNs diagnosis in 62% of cases and uncovered 33% of iPCLs as mPCNs with 100% specificity. It adds complementary value to standard cyst fluid markers offering a simple and cost-effective tool for improving PCL diagnosis by EUS-FNA.</p>","PeriodicalId":10278,"journal":{"name":"Clinical and Translational Gastroenterology","volume":" ","pages":"e00887"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12456567/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144574940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unequal Burdens: Irritable Bowel Syndrome in Sexual and Gender Minority Communities vs Cisgender Heterosexual Individuals.","authors":"Sara Alejandra Reyes-Diaz, Bryan Adrian Priego-Parra, Héctor Ricardo Ordaz-Alvarez, Emma Lorena Núñez-Jiménez, Claudia Leticia Dorantes-Nava, Fátima Higuera-de la Tijera, Mercedes Amieva-Balmori, Christopher Velez, José María Remes-Troche","doi":"10.14309/ctg.0000000000000883","DOIUrl":"10.14309/ctg.0000000000000883","url":null,"abstract":"<p><strong>Introduction: </strong>Irritable bowel syndrome (IBS) is a disorder of gut-brain interaction that negatively impacts quality of life. Given the significant health disparities faced by the sexual and gender minority (SGM) communities, it is essential to explore IBS within the context of sexual orientation and gender identity (SOGI). This study aimed to compare the severity of gastrointestinal and psychological symptoms between cisgender heterosexual and SGM individuals with IBS.</p><p><strong>Methods: </strong>This cross-sectional study recruited 718 participants, with 60.7% being women and a median age of 22. Of these, 542 (75.5%) identified as cisgender heterosexuals, and 176 (24.5%) identified as SGM. Participants, including both patients with IBS and healthy controls (HCs), completed a 60-item electronic survey addressing SOGI, the Rome IV IBS criteria, the Hospital Anxiety and Depression Scale, and the Irritable Bowel Syndrome Severity Scale (IBS-SSS). Statistical analyses included the Student t test, Wilcoxon rank-sum test, Kruskal-Wallis test, and Pearson or Spearman correlations.</p><p><strong>Results: </strong>SGM individuals with IBS reported significantly higher IBS-SSS scores ( P = 0.032) and anxiety levels ( P = 0.032) than their cisgender heterosexual counterparts. In addition, the prevalence of lesbian women was higher in the IBS group compared with healthy controls ( P = 0.041). Cisgender heterosexual participants were more likely to report mild IBS symptoms compared with LGBTQIA+ participants ( P = 0.025).</p><p><strong>Discussion: </strong>SGM individuals with IBS experience more severe symptoms and greater psychological distress compared with cisgender heterosexuals. These findings underscore the need to consider SOGI in health care to ensure that management strategies for IBS are inclusive and effectively address the unique needs of all individuals.</p>","PeriodicalId":10278,"journal":{"name":"Clinical and Translational Gastroenterology","volume":" ","pages":"e00883"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12456516/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144574941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral Indomethacin for Chronic Pancreatitis: Results From the PAIR Randomized Placebo-Controlled Trial.","authors":"Samuel Han, Santhi Swaroop Vege, Phil A Hart, Jami L Saloman, Jun Xu, Liang Li, Zobeida Cruz-Monserrate, Tonya M Palermo, Rachel Hill, Wenrui Hao, Dhiraj Yadav, Mark Topazian, Darwin L Conwell","doi":"10.14309/ctg.0000000000000888","DOIUrl":"10.14309/ctg.0000000000000888","url":null,"abstract":"<p><strong>Introduction: </strong>Chronic pancreatitis (CP) remains difficult to manage with few treatment options. Prior studies have implicated prostaglandin E 2 (PGE 2 ) in mediating chronic inflammation in the pancreas. Therefore, we aimed to evaluate whether indomethacin, a cyclooxygenase-2 enzyme inhibitor, would reduce PGE 2 levels in CP.</p><p><strong>Methods: </strong>In this pilot multicenter randomized controlled trial, participants with CP received oral indomethacin (50 mg) or placebo twice daily for 28 days. Measurement of PGE 2 levels in pancreatic fluid collected endoscopically after secretin administration at baseline and posttreatment (day 28) was performed. Quality of life and pain were also assessed at baseline and posttreatment.</p><p><strong>Results: </strong>A total of 27 participants were randomized (indomethacin = 13, placebo = 14). Although PGE 2 levels decreased after treatment in pancreas fluid, plasma, and saliva in the indomethacin group, there was no significant difference in mean change in pancreas fluid PGE 2 levels between the indomethacin and placebo groups (-457.7 pg/mL vs -840.4 pg/mL, P = 0.25). There was also no significant change in pain severity composite score (-1.3 indomethacin vs -0.5 placebo, P = 0.33), but the improvement in pain interference score (-2.9 indomethacin vs -0.4, P = 0.058) trended toward significance. There was no difference in adverse events between the 2 groups.</p><p><strong>Discussion: </strong>In this phase 1/2 study, oral indomethacin was safe and well tolerated by patients with CP. Although there was no significant difference in change in PGE 2 levels, further studies are needed to determine the effect of indomethacin on the inflammatory pathway of CP and patient-centered outcomes.</p>","PeriodicalId":10278,"journal":{"name":"Clinical and Translational Gastroenterology","volume":" ","pages":"e00888"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12456583/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144574939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Gastric Peristalsis Using Cine MRI in Healthy Subjects and Patients With Functional Dyspepsia.","authors":"Shotaro Oki, Tsutomu Takeda, Mariko Hojo, Shunsuke Nakamura, Takuya Kanazawa, Momoko Yamamoto, Tomoyo Iwano, Hisanori Utsunomiya, Ryota Uchida, Daiki Abe, Nobuyuki Suzuki, Atsushi Ikeda, Yoichi Akazawa, Kumiko Ueda, Hiroya Ueyama, Tomoyoshi Shibuya, Shuko Nojiri, Daisuke Asaoka, Andrea Todisco, Shuji Sato, Ryohei Kuwatsuru, Akihito Nagahara","doi":"10.14309/ctg.0000000000000900","DOIUrl":"10.14309/ctg.0000000000000900","url":null,"abstract":"<p><strong>Introduction: </strong>Functional dyspepsia (FD) is subdivided into postprandial distress syndrome (PDS) and epigastric pain syndrome (EPS), each with a different pathophysiological mechanisms driving the symptoms of these syndromes. Cine MRI aids observation in any continuous cross-section and measures gastrointestinal peristalsis without radiation exposure. In this study, we aimed to evaluate gastric peristalsis in FD using cine MRI.</p><p><strong>Methods: </strong>This study was a prospective interventional study. Patients diagnosed with FD according to ROME IV diagnostic criteria were included. Cine MRI was performed before and after the test meal. Gastric maximum short axis diameter, amplitude, contraction frequency, peristaltic wave height, peristaltic wave velocity, and gastric motility index were evaluated and compared between healthy control (HC) and patients with FD (PDS/EPS).</p><p><strong>Results: </strong>This study consisted of 18 HC and 31 patients with FD (including 22 with PDS and 9 with EPS). Preprandial comparison of the HC, PDS, and EPS groups showed no significant difference. Postprandial comparison of the 3 groups showed significant differences in maximum short axis diameter of fornix (HC: 51.5 ± 9.1/PDS: 47.1 ± 10.3/EPS: 59.0 ± 13.6 mm, P = 0.045), amplitude of fornix (HC: 7.3 ± 5.1/PDS: 12.1 ± 4.3/EPS: 11.3 ± 8.7 mm, P = 0.009), contraction frequency (HC: 2.9 ± 0.3/PDS: 2.7 ± 0.5/EPS: 2.6 ± 0.2 times/min, P = 0.007), peristaltic wave height (HC: 14.9 ± 4.0/PDS: 9.2 ± 2.5/EPS: 9.5 ± 3.2 mm, P < 0.001), and gastric motility index (HC: 24.5 ± 7.1/PDS: 16.8 ± 6.1/EPS: 15.9 ± 6.3 mm 2 /s, P = 0.002).</p><p><strong>Discussion: </strong>Cine MRI can be used to visually evaluate gastric peristalsis dysfunction and impaired gastric accommodation in FD.</p>","PeriodicalId":10278,"journal":{"name":"Clinical and Translational Gastroenterology","volume":" ","pages":"e00900"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12456574/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144774760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dietary and Circulating Vitamins, Polymorphisms of Vitamin Metabolism Genes, and the Risk of Gastrointestinal Cancers: A Systematic Review and Meta-Analysis.","authors":"Xin-Ling Wang, Heng-Min Xu, Zhi-Qiang Hu, Kai-Feng Pan, Wen-Qing Li","doi":"10.14309/ctg.0000000000000899","DOIUrl":"10.14309/ctg.0000000000000899","url":null,"abstract":"<p><strong>Introduction: </strong>Vitamin intake may reduce gastrointestinal cancer risk, but how genetic polymorphisms in vitamin metabolism affect this association remains unclarified. This meta-analysis examined whether genetic polymorphisms in vitamin metabolism influence the association between dietary and circulating vitamins and the risk of gastrointestinal cancers.</p><p><strong>Methods: </strong>Literature search was conducted to gather studies investigating the associations between vitamins, genetic polymorphisms, and gastrointestinal cancer risk. Statistical analyses were conducted using \"meta\" package in R.</p><p><strong>Results: </strong>Our meta-analysis incorporated 64 studies on colorectal cancer (CRC), gastric cancer, and esophageal cancer, focusing on vitamin B and vitamin D. High dietary intake of vitamin B was significantly associated with reduced gastrointestinal cancer risk (odds ratio [OR] 0.84, 95% confidence interval [CI] 0.79-0.90), as was its circulating level (OR 0.53, 95% CI 0.36-0.78). Individuals harboring the MTHFR 1298 AA/AC and CC genotypes demonstrated varying association of CRC risk with dietary vitamin B intake ( P -het = 0.04), whereas the significant inverse association of circulating vitamin B with CRC risk was found only for MTHFR 677 TT carriers (OR 0.57, 95% CI 0.33-0.97), but not for the CC/CT genotype (OR 0.98, 95% CI 0.80-1.21, P -het = 0.06). High dietary (OR 0.69, 95% CI 0.53-0.90) and circulating vitamin D levels (OR 0.74, 95% CI 0.59-0.94) significantly lowered gastrointestinal cancer risk. The inverse association between circulating vitamin D and CRC risk was exclusively yielded for VDR TaqI Tt/tt carriers (OR 0.52, 95% CI 0.28-0.95), other than the TT genotype (OR 0.91, 95% CI 0.70-1.19, P -het = 0.10).</p><p><strong>Discussion: </strong>High dietary and circulating vitamin B and vitamin D levels were associated with lowered gastrointestinal cancer risk, and the associations may be modified by certain genetic variations in vitamin metabolism pathways.</p>","PeriodicalId":10278,"journal":{"name":"Clinical and Translational Gastroenterology","volume":" ","pages":"e00899"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12456602/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144774759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to Tahir and Sajid.","authors":"Krzysztof Dąbkowski, Karolina Skonieczna-Żydecka, Katarzyna Gaweł, Wojciech Marlicz, Piotr Szredzki, Andrzej Białek","doi":"10.14309/ctg.0000000000000896","DOIUrl":"10.14309/ctg.0000000000000896","url":null,"abstract":"","PeriodicalId":10278,"journal":{"name":"Clinical and Translational Gastroenterology","volume":" ","pages":"e00896"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12456494/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145014014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}