Climacteric最新文献

{"title":"Menopausal symptoms and risk factors in Chinese women: a multicenter cross-sectional study.","authors":"Ruiyi Tang, Qingyuan Liu, Jie Li, Mei Li, Hongxia Wang, Qi Yu","doi":"10.1080/13697137.2025.2500563","DOIUrl":"10.1080/13697137.2025.2500563","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to examine menopausal symptoms and their associated factors among premenopausal, perimenopausal and postmenopausal groups of middle-aged Chinese women.</p><p><strong>Methods: </strong>The nationwide cross-sectional study involved 9740 middle-aged women from 115 medical centers across 27 provinces in China. Logistic regression analyses were performed to explore the associations between menopausal symptom severity and age, menopausal status, body mass index (BMI), smoking, employment status, income, education level, exercise and alcohol use.</p><p><strong>Results: </strong>Among the 9740 participants, 17.6% (<i>n</i> = 1711) were premenopausal, 38.3% (<i>n</i> = 3730) were perimenopausal and 44.1% (<i>n</i> = 4299) were postmenopausal. The likelihood of moderate to severe menopausal symptoms was positively associated with age (odds ratio [OR] 1.10; 95% confidence interval [CI] 1.09-1.11; <i>p</i> < 0.001), perimenopause (OR 2.15; 95% CI 1.90-2.45; <i>p</i> < 0.001) and postmenopausal stage (OR 5.96; 95% CI 5.25-6.77; <i>p</i> < 0.001), smoking (OR 1.96; 95% CI 1.39-2.77; <i>p</i> < 0.001) and unemployment (OR 1.47; 95% CI 1.31-1.65; <i>p</i> < 0.001). In contrast, higher income was inversely associated with symptom severity (OR 0.69; 95% CI 0.58-0.82; <i>p</i> < 0.001). BMI demonstrated a positive association with symptom severity in premenopausal women.</p><p><strong>Conclusions: </strong>Age, menopausal status, smoking, unemployment and lower income were associated with more severe menopausal symptoms.</p>","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"312-318"},"PeriodicalIF":2.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144101443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Variations in the prevalence of premature and early menopause in low and middle-income regions: a cross-sectional study.","authors":"Sydney Ross, Sol P Juárez","doi":"10.1080/13697137.2025.2500561","DOIUrl":"10.1080/13697137.2025.2500561","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to examine differences in premature and early menopause across various regions in low and middle-income countries (LMICs).</p><p><strong>Methods: </strong>Data for 55 LMICs from the Demographic and Health Surveys (2013-2023) were classified into nine regions. Proportions of premature (aged <40 years) and early (aged <45 years) menopause were calculated. Logistic regressions adjusted for covariates were also run.</p><p><strong>Results: </strong>The proportion of women in premature menopause ranged from 1.58% in the European and Eastern Mediterranean regions to 6.87% in Southern Africa. For early menopause, proportions ranged from 4.92% in the Eastern Mediterranean region to 15.21% in the Americas. The Eastern Mediterranean region had systematic lower odds across menopause categories, even after the adjustments for relevant covariates.</p><p><strong>Conclusion: </strong>Significant variation exists in the proportion of the different age at menopause categories within LMIC regions. Higher proportions of premature and early menopause were found in all LMIC regions compared to those reported in current literature from high-income countries. A global health perspective on menopause is urgently needed, especially in relation to the increased disease risks with early and premature menopause, such as cardiovascular disease.</p>","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"360-364"},"PeriodicalIF":2.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144092975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"REDLINC: two decades of collaborative insights into menopause and women's health in Latin America.","authors":"Konstantinos Tserotas, Juan Enrique Blumel","doi":"10.1080/13697137.2025.2501255","DOIUrl":"10.1080/13697137.2025.2501255","url":null,"abstract":"<p><p>The Collaborative Group for Research of the Climacteric in Latin America (REDLINC) was established 20 years ago and comprises physicians who specialize in menopause medicine to acquire local information and understand the health needs of our population. Since then, 12 collaborative multinational studies have been conducted. Some of our most relevant results are the average age of menopause in Latin America (48.6 years), and the significant impact on quality of life, metabolic syndrome, sleep issues, sexual dysfunction, anxiety, depression, muscle pain, low muscle mass and mild cognitive decline. Also, we report variations in menopausal hormone therapy (MHT) prescriptions, noting that the tendency to prescribe is stronger among physicians themselves than toward patients. Finally, several factors contribute to the prevention, alleviation and treatment of menopausal changes in women, such as obesity control, exercise, higher education, utilization of MHT and seeking help from menopause practitioners. This article highlights the gathered information on Latin American women, which has been implemented for patients' better understanding. Physicians' awareness has grown, protocols have been adapted to accommodate our healthcare realities and patients are seeking menopause healthcare practitioners. International collaboration is key to the success of this project.</p>","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"220-229"},"PeriodicalIF":2.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144246745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Menopausal symptoms among perimenopausal women in rural Turkey: a cross-sectional study.","authors":"Ipek Betul Ozcivit Erkan, Atilim Gulcicek, Ugurcan Sayili, Vasfiye Bayram Deger, C Tamer Erel, Levent M Senturk","doi":"10.1080/13697137.2025.2490243","DOIUrl":"10.1080/13697137.2025.2490243","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate the prevalence and severity of menopausal symptoms among perimenopausal women in a rural area of southeastern Turkey and their association with sleep quality, depression and sociodemographic and lifestyle-related factors.</p><p><strong>Methods: </strong>This cross-sectional study included 122 perimenopausal women aged 40-55 years residing in southeastern rural Turkey. Participants completed the Beck Depression Inventory (BDI), the Menopause Rating Scale (MRS) and the Pittsburgh Sleep Quality Index (PSQI), alongside demographic data collection.</p><p><strong>Results: </strong>The median age was 46 years (43-49 years). Higher MRS scores were significantly linked to a sedentary lifestyle, poor self-rated health and concerns about partner infidelity. MRS total scores were moderately correlated with global PSQI scores (<i>r</i> = 0.49, <i>p</i> < 0.001) and strongly correlated with BDI scores (<i>r</i> = 0.71, <i>p</i> < 0.001). Severe menopausal symptoms were significantly associated with poor sleep quality (odds ratio [OR] = 2.62; 95% confidence interval [CI]: 1.16-5.95), mild to severe depression (OR = 4.78; 95% CI: 2.08-10.98) and poor self-rated general health (OR = 2.76; 95% CI: 1.03-7.41), even after adjusting for age, parity and body mass index.</p><p><strong>Conclusions: </strong>Perimenopausal women in southeastern rural Turkey experience severe menopausal symptoms that are significantly associated with self-rated general health, sleep quality and depression.</p>","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"304-311"},"PeriodicalIF":2.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143967529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Menopausal symptoms: what are the differences between the West and the East?","authors":"Ruiyi Tang, Qingyuan Liu, Qi Yu","doi":"10.1080/13697137.2025.2503880","DOIUrl":"https://doi.org/10.1080/13697137.2025.2503880","url":null,"abstract":"<p><p>The characteristics of menopause symptoms exhibit considerable variation across different countries and regions. Understanding these variations is crucial for developing strategies to manage the menopausal symptoms specific to each region. A comparative analysis of menopausal symptoms between the East and the West is presented, based on a review of the epidemiological literature and data. In the East, the age of menopause and the onset of the menopausal symptoms were observed to occur slightly earlier than in the West. The two most commonly reported menopausal symptoms in western countries are hot flushes and sleeplessness, whereas Asian women mostly report somatic symptoms. The reported prevalence of menopausal symptoms varies considerably and differs substantially between the studies. These variations may be related to research methods, sample size, ethnicity, culture, socioeconomic differences, menopausal status and other factors.</p>","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"1-6"},"PeriodicalIF":2.9,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Profile and risk stratification for sarcopenia in postmenopausal women.","authors":"Marcelo Luis Steiner, Larissa Gabrielli Lima de Campos, Marina Martinelli Sonnenfeld, Tayná Gueler Silva, Mariliza Henrique da Silva, Rodolfo Strufaldi, Cesar Eduardo Fernandes, Luciano de Melo Pompei","doi":"10.1080/13697137.2025.2495310","DOIUrl":"https://doi.org/10.1080/13697137.2025.2495310","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to assess the risk factors associated with sarcopenia and identify risk profiles through cluster analysis in postmenopausal women treated at specialized outpatient clinics.</p><p><strong>Methods: </strong>A retrospective cross-sectional study evaluated data from 287 postmenopausal women. Sarcopenia was determined by handgrip and gait speed testing. Cluster analysis was applied to identify risk subgroups, and logistic regression to identify factors associated with sarcopenia.</p><p><strong>Results: </strong>Sarcopenia was identified in 18.50% of women. Advanced age (odds ratio [OR] = 1.12; 95% confidence interval [CI]: 1.07-1.16; <i>p</i> < 0.01), number of pregnancies (OR = 1.14; 95% CI: 1.00-1.29; <i>p</i> = 0.04), hip Fracture Risk Assessment Tool (FRAX) (OR = 1.29; 95% CI: 1.12-1.49; <i>p</i> < 0.01), systemic arterial hypertension (OR = 3.20; 95% CI: 1.66-6.17; <i>p</i> < 0.01) and multiple comorbidities (OR = 2.46; 95% CI: 1.19-5.09, <i>p</i> = 0.01) were associated with higher risk for sarcopenia. Cluster analysis revealed an increased risk profile for women who were aged over 70 years, multiparous, hypertensive, with hip FRAX greater than 3% and with major fractures greater than 6%.</p><p><strong>Conclusion: </strong>Postmenopausal women with sarcopenia are more likely to have fragility fractures at 10 years, to be older, multiparous and hypertensive, and to have multiple comorbidities.</p>","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"1-7"},"PeriodicalIF":2.9,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of menopause hormone therapy and serotonin reuptake inhibitors.","authors":"Natalia Pereira de Oliveira, Luciano de Melo Pompei","doi":"10.1080/13697137.2025.2486051","DOIUrl":"https://doi.org/10.1080/13697137.2025.2486051","url":null,"abstract":"<p><strong>Objective: </strong>Postmenopausal hypoestrogenism may cause significant changes in the oral cavity, interfering with inflammatory mechanisms such as salivary secretion. This study aimed to compare the salivary flow, pH levels and prevalence of dry mouth in postmenopausal women treated with hormone replacement therapy (HRT), those treated with selective serotonin reuptake inhibitors (SSRIs) and those without treatment.</p><p><strong>Methods: </strong>Ninety postmenopausal women participated in the study. Of these, 30 used HRT, 30 used SSRIs and 30 did not receive any treatment (control). Salivary flow was measured using stimulated sialometry, while the pH level was measured using pH strips. Meanwhile, a questionnaire was used to assess for xerostomia.</p><p><strong>Results: </strong>The salivary flow measurements were 1.66 ± 0.49 ml/min for the HRT group, 1.23 ± 0.50 ml/min for the SSRI group and 1.68 ± 0.65 ml/min for the control group (<i>p</i> = 0.005 for comparison). The pH values were 7.13 ± 0.43, 7.0 ± 0.26 and 6.97 ± 0.41 for the HRT, SSRI and control groups, respectively. Xerostomia was reported in 60% of women receiving HRT, 46.7% receiving SSRIs and 26.7% of the controls (<i>p</i> = 0.033).</p><p><strong>Conclusion: </strong>Women using SSRIs had lower salivary flow than the HRT or control group. However, xerostomia was more prevalent in women receiving HRT.</p>","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"1-5"},"PeriodicalIF":2.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143980768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Severe obesity and menopause symptoms are associated with cognitive impairment in postmenopausal women from Latin America.","authors":"Juan Enrique Blümel, Maria Soledad Vallejo, Peter Chedraui, Socrates Aedo, Marcio Alexandre Hipolito Rodrigues, Carlos Salinas, Konstantinos Tserotas, Andres Calle, Maribel Dextre, Alejandra Elizalde, Carlos Escalante Gomez, Gustavo Gómez-Tabares, Álvaro de Jesus Monterrosa-Castro, Maria T Espinoza, Monica Ñañez, Eliana Ojeda, Claudia Rey, Doris Rodríguez-Vidal","doi":"10.1080/13697137.2025.2491637","DOIUrl":"https://doi.org/10.1080/13697137.2025.2491637","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate the association between obesity and cognitive impairment.</p><p><strong>Methods: </strong>This study is a sub-analysis of an observational, cross-sectional study in nine Latin American counties. Sociodemographic, clinical and anthropometric data were collected, and cognition was assessed using the Montreal Cognitive Assessment (MoCA) tool in 722 postmenopausal women.</p><p><strong>Results: </strong>The mean age, body mass index (BMI) and years of education of the cohort were 56.9 years, 26.8 kg/m² and 13.6 years, respectively. Women with cognitive impairment, compared to those without, had a higher BMI (27.8 ± 5.9 vs. 26.6 ± 4.9 kg/m², <i>p =</i> 0.037), had more children (3.1 ± 2.4 vs. 2.5 ± 1.7, <i>p =</i> 0.023), experienced more severe menopausal symptoms (56.3% vs. 31.9%, <i>p</i> < 0.001) and presented more comorbidities (60.0% vs. 43.8%, <i>p =</i> 0.006). They also had fewer years of study (10.8 ± 5.1 vs. 13.9 ± 4.9 years, <i>p =</i> 0.001), were less physically active (35.0% vs. 49.1%, <i>p =</i> 0.018) and were less likely to use menopausal hormone therapy (MHT) (11.3% vs. 28.8%, <i>p =</i> 0.001). In binary logistic regression analysis, BMI ≥ 35.0 kg/m² (odds ratio [OR] 2.27, 95% confidence interval [CI] 1.08-4.76) and severe menopausal symptoms (OR 2.10, 95% CI 1.29-3.43) were associated with cognitive impairment. In the model, factors related to lower risk were ever use of MHT (OR 0.44, 95% CI 0.21-0.92) and having more years of education (OR 0.38, 95% CI 0.20-0.64).</p><p><strong>Conclusion: </strong>Severe obesity and severe menopausal symptoms increased the risk of cognitive impairment in postmenopausal women, while higher education and ever use of MHT were protective factors.</p>","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"1-6"},"PeriodicalIF":2.9,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143993278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of jazz dance and concurrent training on physical variables in postmenopausal women.","authors":"Danielly Yani Fausto, Julia Beatriz Bocchi Martins, Ana Rafaela Amaral da Rocha, Priscila Rodrigues Gil, Cíntia de la Rocha Freitas, Andreia Pelegrini, Adriana Coutinho de Azevedo Guimarães","doi":"10.1080/13697137.2025.2486052","DOIUrl":"https://doi.org/10.1080/13697137.2025.2486052","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to analyze the effects of jazz dance or concurrent training on the cardiorespiratory fitness (CRF), muscle strength and sleep quality of postmenopausal women.</p><p><strong>Method: </strong>A randomized clinical trial with 6-month and 12-month follow-up was conducted including 70 postmenopausal women (mean age 53.19 ± 3.39 years). Participants were randomized into the jazz dance intervention (JD) group, concurrent training intervention (CT) group and control group (CG). CRF was assessed using the 6-min walk test, muscle strength using the isokinetic dynamometer and sleep quality using the Pittsburgh Sleep Quality Index questionnaire. Generalized estimating equations with post-hoc minimum significant difference were used, and intention-to-treat and protocol adherence analyses were performed.</p><p><strong>Results: </strong>CRF showed changes between groups, times and interactions, but the CT group achieved greater gains compared to the JD group. Isokinetic strength showed long-term intragroup improvement for both intervention groups, at peak extension and flexion. Intergroup differences were observed, with the JD group presenting higher means in peak extension at all times compared to the CG post intervention; however, the CT group achieved higher means compared to the JD group; and at peak flexion, the JD group presented with higher averages compared to the CG post intervention. The JD group showed an improvement in sleep duration in the short term, while the CT group did so at the 6-month follow-up. There were intergroup changes in the reduction in sleep medication in both intervention groups compared to the CG.</p><p><strong>Conclusion: </strong>Both modalities are effective for improving CRF, muscle strength and sleep quality.</p>","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"1-10"},"PeriodicalIF":2.9,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143966805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sexual counseling based on the BETTER model in postmenopausal women: a randomized controlled trial.","authors":"Negin Bahri, Hedyeh Riazi, Zohreh Keshavarz, Ali Montazeri","doi":"10.1080/13697137.2025.2486049","DOIUrl":"https://doi.org/10.1080/13697137.2025.2486049","url":null,"abstract":"<p><strong>Objective: </strong>Sexual dysfunction and sexual dysfunctional beliefs are common problems in postmenopausal women. The purpose of this study was to evaluate the effect of sexual counseling based on the BETTER (Bring up, Explain, Tell, Time, Educate, Record) model in these women.</p><p><strong>Methods: </strong>The randomized controlled trial study was conducted with 106 postmenopausal women in 2023. Eligible women were assigned randomly to the intervention and control groups. Accordingly, the intervention group received two individual counseling sessions based on the BETTER model. The Female Sexual Function Index (FSFI) and the Sexual Dysfunctional Beliefs Questionnaire (SDBQ) were used for collecting data at baseline and 4 weeks after the intervention.</p><p><strong>Results: </strong>The sexual function score in the intervention group increased from 15.97 to 18.51 (<i>p</i> = 0.001), and the score of sexual dysfunctional beliefs decreased from 33.80 to 24.86 (<i>p</i> = 0.001). In the control group, the sexual function score decreased from 19.09 to 18.59 (<i>p</i> = 0.032) and the sexual dysfunctional beliefs score increased from 31.83 to 32.18 (<i>p</i> = 0.111).</p><p><strong>Conclusion: </strong>Sexual counseling based on the BETTER model has demonstrated efficacy in promoting sexual function and diminishing sexual dysfunctional beliefs. Consequently, the use of this model in the sexual health counseling of postmenopausal women can be considered.</p><p><strong>Trial registration: </strong>IRCT20150128020854N12; October 12, 2023. Iranian Registry of Clinical Trials: https://irct.behdasht.gov.ir/user/trial/71128/view.</p>","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"1-8"},"PeriodicalIF":2.9,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143979099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}