Clinical and Experimental Allergy最新文献

{"title":"Polyphenol Intake During Pregnancy and Childhood Asthma and Atopic Disorders: A Systematic Review.","authors":"Rachel J Morgan, Cassidy Du Berry, Martin O'Hely, Lawrence Gray, Sarath Ranganathan, Peter Vuillermin, Peter D Sly","doi":"10.1111/cea.70031","DOIUrl":"https://doi.org/10.1111/cea.70031","url":null,"abstract":"","PeriodicalId":10207,"journal":{"name":"Clinical and Experimental Allergy","volume":" ","pages":""},"PeriodicalIF":6.3,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143604252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From Ampoules to Auto-Injectors: Advancing Anaphylaxis Management in China.","authors":"Ayel Luis R Batac","doi":"10.1111/cea.70028","DOIUrl":"https://doi.org/10.1111/cea.70028","url":null,"abstract":"","PeriodicalId":10207,"journal":{"name":"Clinical and Experimental Allergy","volume":" ","pages":""},"PeriodicalIF":6.3,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143604249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interaction of Atopy and Airway Dysbiosis Promotes Asthma Persistence in Children With Chronic Rhinosinusitis-5 Years Prospective Study.","authors":"Łukasz Dobrakowski, Piotr Łacwik, Marta Mucha, Błażej Rychlik, Andrzej Błauż, Michał Seweryn, Dominik Strapagiel, Joanna Majak, Wojciech Feleszko, Adam Antczak, Piotr Kuna, Paweł Majak","doi":"10.1111/cea.70029","DOIUrl":"https://doi.org/10.1111/cea.70029","url":null,"abstract":"","PeriodicalId":10207,"journal":{"name":"Clinical and Experimental Allergy","volume":" ","pages":""},"PeriodicalIF":6.3,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143604250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adult Asthma Diagnosis Based on the Japanese Practical Guideline: A Diagnostic Test Accuracy Study.","authors":"Yosuke Fukuda, Naruhito Oda, Takuya Mitsunari, Yuichiro Saito, Kensuke Izumizaki, Yoshihiro Go, Keitaro Kishi, Hironori Sagara, Akihiko Tanaka","doi":"10.1111/cea.70032","DOIUrl":"https://doi.org/10.1111/cea.70032","url":null,"abstract":"<p><p>The Japanese Practical Guidelines for Asthma Management algorithm achieved high sensitivity (87.7%) and specificity (94.5%) for asthma diagnosis. It highlights nocturnal cough and breathlessness, offering a practical asthma diagnostic approach. The algorithm distinguishes asthma from upper respiratory tract infections effectively.</p>","PeriodicalId":10207,"journal":{"name":"Clinical and Experimental Allergy","volume":" ","pages":""},"PeriodicalIF":6.3,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143604248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bone Marrow Mast Cells in Systemic Mastocytosis Exhibit Aberrations in Histamine, Size and Granularity.","authors":"Michiel Beyens, Jessy Elst, Alessandro Toscano, Christel Mertens, Michel Van Houdt, Anke Verlinden, Eva De Backer, Marie-Berthe Maes, Katrien Vermeulen, Didier G Ebo, Vito Sabato","doi":"10.1111/cea.70030","DOIUrl":"https://doi.org/10.1111/cea.70030","url":null,"abstract":"","PeriodicalId":10207,"journal":{"name":"Clinical and Experimental Allergy","volume":" ","pages":""},"PeriodicalIF":6.3,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143572334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnosis and Management of Lipid Transfer Protein Allergy-A BSACI Clinical Practice Statement.","authors":"Susana Marinho, Marina Frleta-Gilchrist, Hannah Hunter, Dominika Murgasova, Nandinee Patel, Stephen Till, Isabel J Skypala","doi":"10.1111/cea.70022","DOIUrl":"https://doi.org/10.1111/cea.70022","url":null,"abstract":"<p><p>Although the most prevalent plant food allergy in the United Kingdom (UK) is pollen food syndrome (PFS), there is increasing evidence that reactions to plant foods could also be due to sensitisation to Lipid Transfer Proteins (LTP). These proteins, highly resistant to heat and processing, are present in raw, cooked and processed plant foods and often provoke moderate to severe symptoms. LTP allergy is common in Mediterranean countries, but there is a lack of epidemiological data from Northern Europe, although small case series have been published characterising LTP allergy in both England and Scotland. To gather further information and aid the development of a clinical practice statement on LTP allergy, a survey was conducted by the British Society of Allergy and Clinical Immunology (BSACI). The results confirmed that LTP allergy is being diagnosed in both children and adults in all areas of the UK. The survey results, along with published UK data, confirm that tree nuts, peanuts, apples, stone fruits, tomatoes and processed foods, such as pizza or curry, are common food triggers. Anaphylactic reactions are not uncommon and are often facilitated by the presence of co-factors such as exercise or alcohol. Unlike LTP allergy in Spain and Italy, UK individuals are also more likely to be sensitised to birch and grass pollen, but this does not appear to reduce the severity of the condition. Diagnosis can be complex; a positive test to individual LTP allergens can only be confirmatory of a diagnosis of LTP allergy when accompanied by a typical clinical history. Management can be difficult, and individualised advice is vital to avoid the exclusion of multiple foods and minimise the likelihood of co-factors. Given the diverse range of foods, co-factor involvement and highly idiosyncratic nature of LTP allergy, the need for adrenaline autoinjectors should always be considered.</p>","PeriodicalId":10207,"journal":{"name":"Clinical and Experimental Allergy","volume":" ","pages":""},"PeriodicalIF":6.3,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143572337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact of Living With Inducible Laryngeal Obstruction.","authors":"Siobhan Ludlow, Lucie Byrne-Davis, Stephen J Fowler","doi":"10.1111/cea.70026","DOIUrl":"https://doi.org/10.1111/cea.70026","url":null,"abstract":"<p><p>Inducible Laryngeal Obstruction (ILO) is an inappropriate, transient, reversible narrowing of the larynx in response to external triggers. The aim of this qualitative study was to develop an in-depth understanding of the experiences of individuals living with ILO and the impact this has on their lives. We describe the impact the disease has on patients, and this should promote clinician awareness of the experience of ILO from the patient's perspective and support a personalised approach to care.</p>","PeriodicalId":10207,"journal":{"name":"Clinical and Experimental Allergy","volume":" ","pages":""},"PeriodicalIF":6.3,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143555963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral Immunotherapy Should Play a Key Role in Preschool Food Allergy Management.","authors":"Lianne Soller, Edmond S Chan, Scott B Cameron, Elissa M Abrams, Sandeep Kapur, Stuart N Carr, Timothy K Vander Leek","doi":"10.1111/cea.70013","DOIUrl":"https://doi.org/10.1111/cea.70013","url":null,"abstract":"<p><p>Food allergies pose significant challenges including the risk for severe allergic reactions. This review article highlights the advantages and disadvantages of the historic standard management approach-avoidance and carrying epinephrine in case of accidental ingestion-and argues, based on accumulating evidence, that oral immunotherapy (OIT) should play a key role in preschool food allergy management. Firstly, our review will highlight pitfalls with the 'wait-and-see' approach to natural resolution of food allergies, with recent data pointing to lower resolution than previously thought. For those who do not outgrow their allergies, waiting until school age to offer OIT means missing the window of opportunity where OIT is safest, and prolongs unnecessary dietary restrictions. For those who do outgrow their allergies, research indicates they may not reintroduce the food due to fear and aversion and can become re-sensitised, putting them at risk of severe reactions. Secondly, the risks associated with allergen avoidance are higher than previously believed. Allergen avoidance is imperfect and carries an increased risk of severe reactions when compared with the risk of severe reactions while on OIT, particularly in preschoolers. Although an allergic reaction can be stressful, it is preferable to have this occur during OIT where caregivers are vigilant following a scheduled dose, rather than having this occur at a potentially unexpected time following an accidental exposure. Lastly, there is a growing body of evidence supporting favourable safety and effectiveness of OIT in preschoolers, and preliminary data suggesting higher likelihood of remission in infants. OIT has the potential to significantly improve quality of life, and future research is needed to answer this important question in preschoolers. In summary, while ongoing research will further clarify cost-effectiveness, long-term adherence and psychosocial impacts of OIT, this review suggests that OIT should play a key role in preschool food allergy management.</p>","PeriodicalId":10207,"journal":{"name":"Clinical and Experimental Allergy","volume":" ","pages":""},"PeriodicalIF":6.3,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143555960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hereditary Angioedema (HAE) in China: Advancing Awareness, Access, Advocacy and Alliances From the Greater Bay Area to the Global HAE Community.","authors":"Philip H Li, Jin-Xian Huang, Can-Tian Wang, Jane C Y Wong, Hao Chen, Bao Chai, Liang Chen, He Lai, Shuo Li, Yan-Hua Liang, Yun-Sheng Liang, Ning Liu, Bing Lu, Bao-Qing Sun, Qin-Tai Yang, Fei Ye, Jiang-Lin Zhang, Shu-Chen Zhang, Zuo-Tao Zhao, Min Zhou, Xian-Biao Zou, Guang-Hui Liu, Kai Guan","doi":"10.1111/cea.70014","DOIUrl":"https://doi.org/10.1111/cea.70014","url":null,"abstract":"<p><p>The article offers an overview of the progress in managing Hereditary Angioedema (HAE) in China, with a specific focus on the Greater Bay Area (GBA). Through the '4As' framework-Awareness, Access, Advocacy and Alliance-the article explores the challenges and advancements in HAE care. In terms of collaborative initiatives such as the HAE-ASIA (Angioedema Screening In Asia) collaboration and the GBA HAE Alliance \"Hub-and-Spoke model\" aim to bridge the gap between East and West, providing optimal patient care and advancing HAE management. By bridging the gap between East and West, the GBA aims to deliver optimal patient care and advance HAE management. Moving forward, it will be essential to persist in nurturing national and international collaborations, not only within China but also extending beyond its borders. These partnerships encourage the exchange of knowledge, research, and best practices, all of which are critical in propelling forward the care of HAE. By uniting as a worldwide community, we can significantly advance efforts to improve the quality of life for those affected by HAE across the globe.</p>","PeriodicalId":10207,"journal":{"name":"Clinical and Experimental Allergy","volume":" ","pages":""},"PeriodicalIF":6.3,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143555958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring Treatment Adherence in Allergic Rhinitis, Inflammasome Mechanisms in Asthma, and Chronic Cough: Insights From Recent Studies","authors":"Mohamed H. Shamji,&nbsp;Robert J. Boyle","doi":"10.1111/cea.70023","DOIUrl":"10.1111/cea.70023","url":null,"abstract":"<p>\u0000 \u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure>\u0000 </p>","PeriodicalId":10207,"journal":{"name":"Clinical and Experimental Allergy","volume":"55 3","pages":"210-212"},"PeriodicalIF":6.3,"publicationDate":"2025-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cea.70023","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143536675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}