Clinical and Experimental Allergy最新文献

{"title":"Variants at 8p21.3 Mediate BMP1 Expression, Contributing to Higher Atopic Dermatitis Risk.","authors":"Jia Yi Karen Wong, Yang Yie Sio, Yi Ying Eliza Lim, Yee-How Say, Kavita Reginald, Fook Tim Chew","doi":"10.1111/cea.70332","DOIUrl":"https://doi.org/10.1111/cea.70332","url":null,"abstract":"","PeriodicalId":10207,"journal":{"name":"Clinical and Experimental Allergy","volume":" ","pages":""},"PeriodicalIF":5.2,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147855942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fixed Very-Low-Dose Oral Immunotherapy in Infants and Toddlers With Low-Threshold Egg, Milk or Wheat Allergy: A Prospective Cohort Study.","authors":"Katsumasa Kitamura, Teruaki Matsui, Yoshihiro Takasato, Shiro Sugiura, Komei Ito","doi":"10.1111/cea.70336","DOIUrl":"https://doi.org/10.1111/cea.70336","url":null,"abstract":"","PeriodicalId":10207,"journal":{"name":"Clinical and Experimental Allergy","volume":" ","pages":""},"PeriodicalIF":5.2,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Circulating 1-Methylnicotinamide Predicts Dupilumab Response in Adult Asthma: A Prediction Model.","authors":"Woori Chae, Jin An, Wonjae Lee, Eunse Kim, Chae Eun Lee, Hyouk-Soo Kwon, Woo-Jung Song, You Sook Cho, Taehoon Lee, Ga-Young Ban, Byung-Jae Lee, So-Young Park, Young-Hee Nam, Chan Sun Park, Joo-Hee Kim, Min-Suk Yang, Sang-Ha Kim, Hye-Kyung Park, Jeong-Hee Choi, Sujeong Kim, Min-Hye Kim, Ji-Su Shim, Kyung-Min Ahn, Han Ki Park, Jae-Woo Jung, Sang Min Lee, Jae-Woo Kwon, Gyu Young Hur, Byung Keun Kim, Ji-Yong Moon, Kyoung-Hee Sohn, Pankaj K Bhavsar, Ian M Adcock, Kian Fan Chung, Joo-Youn Cho, Tae-Bum Kim","doi":"10.1111/cea.70334","DOIUrl":"https://doi.org/10.1111/cea.70334","url":null,"abstract":"","PeriodicalId":10207,"journal":{"name":"Clinical and Experimental Allergy","volume":" ","pages":""},"PeriodicalIF":5.2,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Allergic Rhinitis Treatments on Utilities and Quality of Life: A MASK-air Study.","authors":"Nuno Lourenço-Silva, Bernardo Sousa-Pinto, Antonio Bognanni, Ana Margarida Pereira, João Coutinho-Almeida, Rita Amaral, Luisa Brussino, Mattia Giovannini, Bilun Gemicioglu, Violeta Kvedariene, Desiree E Larenas-Linnemann, Manuel Marques-Cruz, Nikolaos G Papadopoulos, Nhân Pham-Thi, Frederico S Regateiro, Sanna K Toppila-Salmi, Boleslaw Samolinski, Joaquin Sastre, Luís Taborda-Barata, Arunas Valiulis, Leticia de Las Vecillas, Maria Teresa Ventura, Oliver Pfaar, João A Fonseca, Torsten Zuberbier, Ludger Klimek, Jean Bousquet, Rafael José Vieira","doi":"10.1111/cea.70335","DOIUrl":"https://doi.org/10.1111/cea.70335","url":null,"abstract":"<p><strong>Background: </strong>Allergic rhinitis displays a relevant impact on quality of life. Medications used in the treatment of rhinitis have been assessed on their impact on rhinoconjunctivitis-related quality of life, but not on generic health-related quality of life metrics, such as utilities or EQ-5D visual analogue scale (VAS) levels. This study aimed to compare different medication classes and individual medications on utilities and EQ-5D VAS levels using data from a mobile app.</p><p><strong>Methods: </strong>We conducted an observational study using direct patient data from the MASK-air mobile application, collected between May 2015 and December 2024. We compared rhinitis medication classes and individual medications on health utilities (computed from the EQ-5D-5L questionnaire) and the EQ-5D VAS. To account for confounding, we employed inverse probability treatment weighting based on propensity scores, adjusting for demographics, baseline symptom control, and asthma status.</p><p><strong>Results: </strong>The study analysed 69,973 observations with EQ-5D VAS data and 842 observations with utility data. At the medication class level, fixed combinations of intranasal antihistamines and corticosteroids were associated with improvements in EQ-5D VAS (mean difference = 1.900; 95% CI = 1.316-2.484) and utilities (mean difference = 0.022; 95% CI = -0.015 to 0.059) compared with oral antihistamines (OAH). Intranasal antihistamines were associated with lower EQ-5D VAS and utility scores than other intranasal treatments. For individual medications, mometasone was associated with a lower EQ-5D VAS than budesonide and fluticasone furoate, while fexofenadine and levocetirizine tended to be associated with lower VAS values than other OAH.</p><p><strong>Conclusion: </strong>Fixed combinations of intranasal antihistamines and corticosteroids were associated with better quality-of-life than oral antihistamines and intranasal antihistamines. These findings could support future cost-effectiveness analyses.</p>","PeriodicalId":10207,"journal":{"name":"Clinical and Experimental Allergy","volume":" ","pages":""},"PeriodicalIF":5.2,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"When a Positive IgE Test Is Not an Allergy: Distinguishing Sensitisation, Cross-Reactivity and Irritant Responses in Clinical Practice.","authors":"Neeraj Gupta, Sowmya Arudi Nagarajan","doi":"10.1111/cea.70315","DOIUrl":"https://doi.org/10.1111/cea.70315","url":null,"abstract":"","PeriodicalId":10207,"journal":{"name":"Clinical and Experimental Allergy","volume":" ","pages":""},"PeriodicalIF":5.2,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Plant-Based Drinks for Children Aged 1 Year and Over.","authors":"Aisling Phelan, Claudia Gore, Robert J Boyle","doi":"10.1111/cea.70333","DOIUrl":"https://doi.org/10.1111/cea.70333","url":null,"abstract":"","PeriodicalId":10207,"journal":{"name":"Clinical and Experimental Allergy","volume":" ","pages":""},"PeriodicalIF":5.2,"publicationDate":"2026-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Gap Between Prescription and Practice: Adrenaline Autoinjector Carriage in an Australian Cohort.","authors":"Jason Chun Lao, Yi Tong Vincent Aw, Reina Zaragoza, Jamma Li, Therese Boyle, Suran L Fernando, Shruti Swamy","doi":"10.1111/cea.70316","DOIUrl":"https://doi.org/10.1111/cea.70316","url":null,"abstract":"","PeriodicalId":10207,"journal":{"name":"Clinical and Experimental Allergy","volume":" ","pages":""},"PeriodicalIF":5.2,"publicationDate":"2026-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147811729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High Sensitisation but Low Clinical Reactivity to Edible Insects in Shellfish-Allergic Individuals.","authors":"Marta Perez-Montoya, Ana Morales-Hidalgo, Alicia Gomez-Lopez, Marcela Valverde-Monge, Leyre Baptista Serna, Carlos Villalobos-Vilda, Jose Antonio Cañas, Victoria Del Pozo, Joaquin Sastre, Blanca Barroso, Diana Betancor","doi":"10.1111/cea.70223","DOIUrl":"10.1111/cea.70223","url":null,"abstract":"","PeriodicalId":10207,"journal":{"name":"Clinical and Experimental Allergy","volume":" ","pages":"572-575"},"PeriodicalIF":5.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146046144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Human Plasma-Derived C1 Inhibitor for Short-Term Prophylaxis in Hereditary Angioedema With Normal C1 Inhibitor.","authors":"Paula Christina Cavallini de Melo Maricondi, Fernanda Gontijo Minafra, Luis Felipe Ramos Berbel Angulski, Gabriela Andrade Coelho Dias, Herberto José Chong Neto, Faradiba Sarquis Serpa, Eli Mansour, Solange Oliveira Rodrigues Valle, Maria Luiza Oliva-Alonso, Janaira Fernandes Severo Ferreira, Iramirton Figuerêdo Moreira, Clarissa Lucia Tenório Soares Vieira Tavares, Jane da Silva, L Karla Arruda, Mariana Paes Leme Ferriani, José Eduardo Seneda Lemos, Adriana Azoubel-Antunes, Rozana de Fátima Gonçalves, Anete S Grumach","doi":"10.1111/cea.70218","DOIUrl":"10.1111/cea.70218","url":null,"abstract":"","PeriodicalId":10207,"journal":{"name":"Clinical and Experimental Allergy","volume":" ","pages":"565-568"},"PeriodicalIF":5.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146009198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Natural History of Nonsteroidal Anti-Inflammatory Drug-Exacerbated Respiratory Disease: A Retrospective, Single-Centre Study.","authors":"María José Peñalver, Celine Galleani, Consuelo Fernández, Jesús F Crespo","doi":"10.1111/cea.70219","DOIUrl":"10.1111/cea.70219","url":null,"abstract":"","PeriodicalId":10207,"journal":{"name":"Clinical and Experimental Allergy","volume":" ","pages":"569-571"},"PeriodicalIF":5.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145970639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}