{"title":"[PREGNANCY AND OBESITY - PREVENTION OF OBESITY IN THE NEXT GENERATION].","authors":"Sofia Soltsman, Izhar Ben Shlomo","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Obesity is a feature affecting nearly all life aspects. As the burden of obesity is increasing steadily, it leads to the increasing prevalence of diabetes, and most other common non-communicable diseases. A comprehensive approach for the prevention of obesity appears to constitute the most effective intervention to reduce their prevalence worldwide. In this review, we highlight pregnancy as a key period in a woman's life, which can improve compliance with different types of diet, physical activity, and behavioural programs, affecting the next generation's health, and breaking the vicious cycle of family obesity.</p>","PeriodicalId":101459,"journal":{"name":"Harefuah","volume":"164 2","pages":"119-123"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143485142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[MANAGEMENT OF LABOR ANESTHESIA IN A PATIENT WITH EHLERS-DANLOS SYNDROME WHY DOES CHATGPT ERR IN SOURCE REFERENCING?]","authors":"Daphna Idan, Rotem Sisso-Avron, Or Degany","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Ehlers-Danlos Syndrome (EDS) encompasses a spectrum of inherited disorders, characterized by joint hypermobility, skin hyperextensibility, and other features. In some patients, EDS involves the vascular walls, posing a significant clinical challenge due to the resultant propensity for rupture with hemorrhagic complications. Such complications, among others that often occur with EDS, may carry particular importance in the context of pregnancy and labor. This paper presents a patient diagnosed with Ehlers-Danlos Syndrome during her first pregnancy. The patient was planned for elective Cesarean delivery and expressed an interest in regional anesthesia. A literature review was conducted to identify similar cases in which the anesthesia techniques and their potential complications were described, as well as additional risks for EDS patients associated with various anesthesia methods. The review identified only low-quality data, which suggested a higher pain threshold in patients with EDS and an increased risk of bleeding. This case was used to assess the ability of ChatGPT to present a literature review based on reliable sources when the evidence is sparse. The model generated a well-worded response using correct medical terminology, but the report was superficial and provided no data to support clinical decision-making. The model also suggested a different anesthetic approach than the human-generated literature review and supported its findings with links to cited sources. These sources were examined, and concerns regarding their reliability were raised. Lack of reliability remains a major challenge for developers and users of large language models. Fine-tuning (i.e. training the model with examples relevant to specific tasks) which may enhance model output accuracy is discussed in this context.</p>","PeriodicalId":101459,"journal":{"name":"Harefuah","volume":"164 2","pages":"74-76"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143485054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[THE EFFECT OF THE ISRAELI AUTHORITY PLAN TO DIVERT PRIVATE TO PUBLIC FUNDING ON THE RESULTS OF IN VITRO FERTILIZATION TREATMENT OUTCOME].","authors":"Raoul Orvieto, Oshrit Shtossel, Tamar Shtral, Yael Raichenberg, Ravit Nahum","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Israel's public funding policy for in vitro fertilization (IVF) is unique globally, with only minor restrictions. In late 2017, a program was launched to shift IVF treatments from private to public funding in an attempt to reduce waiting times, allowing IVF treatment in both public and private centers within the health basket.</p><p><strong>Objectives: </strong>The study aimed to analyze the impact of this program on IVF treatment outcomes using data from the Clalit-Dan district.</p><p><strong>Methods: </strong>Data from the Clalit-Dan District Health Insurance Fund (2014-2021) were analyzed, comparing IVF outcomes cumulative live birth rates (using Kaplan-Meier curves) in public and private centers.</p><p><strong>Results: </strong>Between the years 2014 and 2021, 14,509 IVF treatment cycles were performed within the health basket in the Dan District. After implementing the 2017 aforementioned programe, IVF cycles in private centers increased, with no change in public centers. Live birth rates were slightly higher in public centers compared to private centers (10.02% vs. 9.04%), but without statistical significance (p=0.13). A noticeable decline in live birth rates was observed after 2018, especially in fresh cycles. No significant differences were found between public and private centers for women aged 20-39 years, but for those aged 40-45 years, public centers had significantly higher live birth rates, particularly in fresh cycles.</p><p><strong>Conclusions: </strong>The 2017 program to shift IVF activity from private to public funding increased the burden on private centers and led to a decline in live birth rates, particularly for women over 40 years of age. The Ministry of Health, being entrusted, among other things, with the supervision and control of the IVF units in Israel, must examine and provide an adequate response to the issues raised above.</p>","PeriodicalId":101459,"journal":{"name":"Harefuah","volume":"164 2","pages":"77-81"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143485145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[ECTOPIC FALLOPIAN TUBE PREGNANCY RELOCATION TO THE UTERINE CAVITY - TRUTH OR FICTION? PRIMUM NON NOCERE].","authors":"Chen Ben David, Udi Ergaz, Yaniv Zipori, Ido Solt","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>In the medical literature there are several case reports of physicians who tried to transfer a gestational sac from the fallopian tube to the uterus. In this article, a review of the scientific literature on the subject was conducted and an answer was provided to the question, truth or fiction? Anyone who deals with early pregnancies, understands the complexity of the implantation process during early pregnancy, and that there is no clear anatomical separation plane in early pregnancy, between the decidua and the early placental villi that penetrate it. Several case reports in the medical literature describe a successful transfer of an ectopic pregnancy from the fallopian tube to the uterine cavity. Those case reports are unreliable, and attempts to reproduce them have not been successful. Currently, attempts should not be made to transfer an ectopic pregnancy into the uterine cavity, as they may endanger the patients' lives - primum non nocere.</p>","PeriodicalId":101459,"journal":{"name":"Harefuah","volume":"164 2","pages":"100-102"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Hippocrates and language models - Primum Non Nocere - First do no harm].","authors":"Sharon Einav, Or Degany, Yehuda Shoenfeld","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Hippocrates and language models - Primum Non Nocere - First do no harm.</p>","PeriodicalId":101459,"journal":{"name":"Harefuah","volume":"164 2","pages":"129"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ravit Yakoby, Ami Neuberger, Moran Szwarcwort Cohen, Sigal Mendelsohn, Raya Abu Abas, Anat Stern
{"title":"[ASPERGILLUS CENTRAL VENOUS CATHETER INFECTION WITH FUNGEMIA IN A PATIENT UNDERGOING HEMODIALYSIS - CASE REPORT].","authors":"Ravit Yakoby, Ami Neuberger, Moran Szwarcwort Cohen, Sigal Mendelsohn, Raya Abu Abas, Anat Stern","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Aspergillus species are an important cause of life-threatening infections in immunocompromised patients. Those considered at high risk include patients with prolonged neutropenia, and patients who underwent bone marrow transplantation. The most common presentation of aspergillosis is invasive aspergillosis (IA) with pulmonary involvement. Microbiologic diagnosis usually involves culture or molecular tests of respiratory tract samples as blood cultures rarely grow this organism. We document an unusual case of Aspergillus fumigatus central venous line infection involving a hemodialysis catheter, with macroscopic mold growing in multiple blood cultures. The infection was probably acquired during hemodialysis treatment in Kenya, while awaiting kidney transplantation.</p>","PeriodicalId":101459,"journal":{"name":"Harefuah","volume":"164 2","pages":"87-89"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143485431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fahmi Shibli, Amir Mari, Matan Siterman, Nir Bar, Mark Teshler, Ram Dickman, Yeshai Ron
{"title":"[TIMED BARIUM SWALLOW: CLINICAL UTILITY, INDICATIONS AND HOW TO INTERPRET THE STUDY].","authors":"Fahmi Shibli, Amir Mari, Matan Siterman, Nir Bar, Mark Teshler, Ram Dickman, Yeshai Ron","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Timed barium swallow (TBS) is a simple non-invasive diagnostic test to evaluate esophageal emptying of liquids. TBS was originally described for the assessment of response to treatment in achalasia patients. Since then, its use has been expanded, including assessment of dysphagia in other esophageal motility disorders.</p><p><strong>Objectives: </strong>To provide a clinical review summarizing the main indications, protocol, interpretation and complementary role of TBS in the diagnosis of esophageal motility disorders.</p><p><strong>Methods: </strong>A working group of gastroenterologists specialized in neurogastroenterology and motility disorders and radiologist reviewed the relevant medical literature on TBS.</p><p><strong>Results: </strong>TBS provides an objective measure of esophagogastric junction (EGJ) opening and esophageal clearance. It is a useful diagnostic tool in achalasia, assessing the severity of EGJ obstruction and response to treatment. TBS complements high-resolution manometry (HRM) in symptomatic EGJ outflow obstruction (EGJOO) to help determining a need for treatment. TBS may also play a role in the assessment of absent contractility and other hypomotility disorders. TBS adds objective data on esophageal emptying which can aid decision-making when HRM is unclear or unavailable.</p><p><strong>Conclusions: </strong>TBS is a simple non-invasive diagnostic test for the evaluation of esophageal dysfunction. In achalasia and EGJOO, combined with a clinical evaluation and HRM findings, TBS provides valuable additional data and can guide treatment decisions.</p>","PeriodicalId":101459,"journal":{"name":"Harefuah","volume":"164 2","pages":"108-113"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143485192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Hippocrates and language models - Primum Non Nocere - First do no harm].","authors":"Yoav Siegler, Ido Solt, Nir Kugelman, Efraim Siegler","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Hippocrates and language models - Primum Non Nocere - First do no harm.</p>","PeriodicalId":101459,"journal":{"name":"Harefuah","volume":"164 2","pages":"128"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[ODONTOGENIC SINUSITIS].","authors":"Idit Tessler, Arkadi Yakirevitch","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Odontogenic sinusitis originates from dental diseases, accounting for 10-14% of total maxillary sinusitis and up to 75% of unilateral cases. This entity develops due to the violation of the Schneiderian membrane of the maxillary sinus by dental pathology and is characterized by unique bacteriology. The characteristic symptoms include unilateral nasal obstruction and purulent rhinorrhea, often without dental pain. A high index of suspicion is warranted when patients present with unilateral symptoms, especially post-dental procedures. Comprehensive clinical examination is crucial for accurate diagnosis, often supplemented by radiographic imaging methods such as computer tomography scans. A multidisciplinary approach involving otolaryngologists, maxillofacial surgeons, and dental specialists is essential for optimal management. Dental infection elimination is the primary treatment step that usually requires surgery. Despite its frequency, odontogenic sinusitis continues to be under-diagnosed due to its non-specific symptomatology and requires a thorough understanding and collaboration across medical specialties for optimal diagnosis and management. The awareness and knowledge of odontogenic sinusitis can enhance early recognition and treatment, ultimately improving patient outcomes.</p>","PeriodicalId":101459,"journal":{"name":"Harefuah","volume":"164 2","pages":"124-125"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143485061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}