Harefuah Pub Date : 2025-05-01

Marina Pekar Zlotin, Yifat Wiener, Hen Yitzhak Sela, Ilia Kleiner, Noa Zafran, Inna Bleicher, Sabina Yogev Sponer, Ron Maymon

{"title":"[DIAGNOSIS AND TREATMENT OF PREGNANT PATIENTS WITH SPLENIC ARTERY ANEURYSM (SAA) IN THE STATE OF ISRAEL: TWO DECADES OF EXPERIENCE AND STILL IT IS A MYSTERY].","authors":"Marina Pekar Zlotin, Yifat Wiener, Hen Yitzhak Sela, Ilia Kleiner, Noa Zafran, Inna Bleicher, Sabina Yogev Sponer, Ron Maymon","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Rupture of splenic artery aneurysm (SAA) during pregnancy or the puerperium is an obstetric emergency endangering the lives of both the pregnant patient and the fetus.Aims: The aim of the current study is to characterize early signs of rupture SAA and recommend optimal management to prevent maternal and fetal mortality.Methods: We conducted a retrospective follow-up study of cases reported in Israel among women diagnosed with SAA during pregnancy and postpartum. Demographics and obstetrical data of maternal and fetal/newborn were collected.Results: We identified 13 cases of SAA in Israel between 2010 and 2023. The timing of the diagnosis ranged from the second to the third trimester (no cases were reported in the first trimester), with 2 cases diagnosed in the post-partum period. Three women (23%) died, and three fetuses did not survive (23%).Conclusions: Rupture of SAA during the pregnancy or in the puerperium is a rare event, however, it is associated with maternal and neonatal mortality. Raising awareness among all healthcare providers to the possible diagnosis of rupture of SAA in pregnant or peri-partum women with nonspecific symptoms, including abdominal pain and hemodynamic deterioration, is crucial for decision making and management of those cases and possibly saving their lives and the lives of their fetuses.Discussion: In cases presented with undefined symptoms, including abdominal pain and hemodynamic deterioration, the clinician should suspect SAA. Awareness to the possible clinical presentation of SAA rupture during pregnancy is crucial and may prevent mortality for both the pregnant patient and her fetus.","PeriodicalId":101459,"journal":{"name":"Harefuah","volume":"164 5","pages":"285-288"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144145330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[GROUP COGNITIVE PROCESSING THERAPY - CPT - A CASE STUDY]. [群体认知加工疗法- CPT -一个案例研究]。

Harefuah Pub Date : 2025-05-01

Hadar Marom Harel, Shahaf Hampel, Orit Yaron Raviv, Tal Weizman

{"title":"[GROUP COGNITIVE PROCESSING THERAPY - CPT - A CASE STUDY].","authors":"Hadar Marom Harel, Shahaf Hampel, Orit Yaron Raviv, Tal Weizman","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Cognitive Processing Therapy (CPT) is one of only a few evidence based therapies that was developed and proven effective for the treatment of Post-Traumatic Stress Disorder (PTSD). Therapy can be administered in an individual or group format. Group CPT was offered in our clinic prior to the onset of the Iron Swords war. Among the participants was G., who was diagnosed with PTSD following an injury that occurred during his military service.Aims: The aim of this report is to present group CPT through the experience of one participant who was diagnosed with PTSD due to a military injury and to discuss the potential utility of such a group to treat PTSD secondary to the Iron Swords war.Background: G was referred to treatment due to decreased functioning and active symptoms of PTSD that persisted several years after his injury. Despite his reservations, he participated in most meetings of group therapy that was based on the CPT protocol.Discussion: In this time of war where trauma is abundant, a group model based on a protocol that was developed specifically to treat PTSD may be useful. In the case presented, group based CPT partially improved PTSD symptoms in a participant with a military based injury. Since then our clinic continues to offer group based CPT therapy which was also provided to a population of survivors of the massacre that took place at the onset of the Iron Swords war.","PeriodicalId":101459,"journal":{"name":"Harefuah","volume":"164 5","pages":"295-298"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144145332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[TYPE 1 DIABETES MELLITUS AND MONOGENIC DIABETES - CAN THE TWO WALK TOGETHER?] 1型糖尿病和单基因糖尿病——两者能共存吗？]

Harefuah Pub Date : 2025-05-01

Nirit Aviran Barak

引用次数: 0

[PLASTICS AND REFRACTION - EXPO - ISRAEL, MAY 28, 2024]. [塑料与折射-以色列博览会，2024年5月28日]。

Harefuah Pub Date : 2025-05-01

Nir Erdinest, Hadas Kfir-Ruzal

引用次数: 0

[ARTIFICIAL INTELLIGENCE TOOLS AND THEIR USE IN MEDICINE CHATGPT - NOT THE ONLY PLAYER IN THE ARENA]. （人工智能工具及其在医学领域的应用——并不是这个领域唯一的参与者）。

Harefuah Pub Date : 2025-05-01

Zvi Weizman, Or Degany, Yehuda Shoenfeld

引用次数: 0

[ARTIFICIAL INTELLIGENCE-ASSISTED LITERATURE REVIEW: A CASE STUDY IN FUMARATE HYDRATASE-DEFICIENT RENAL CELL CARCINOMA]. [人工智能辅助文献综述：富马酸水合酶缺陷肾细胞癌病例研究]。

Harefuah Pub Date : 2025-05-01

Dolev Vaknin, Or Degany, Rotem Sisso-Avron

{"title":"[ARTIFICIAL INTELLIGENCE-ASSISTED LITERATURE REVIEW: A CASE STUDY IN FUMARATE HYDRATASE-DEFICIENT RENAL CELL CARCINOMA].","authors":"Dolev Vaknin, Or Degany, Rotem Sisso-Avron","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Fumarate hydratase-deficient renal cell carcinoma (FHdRCC) is a rare and aggressive form of kidney cancer that presents significant therapeutic challenges. Due to its rarity, treatment decisions often rely on comprehensive literature reviews to identify potential therapeutic options. This article presents a case of a 37-year-old patient with metastatic FHdRCC who showed partial response to Nivolumab but experienced persistent lymphatic involvement and symptoms requiring ongoing intervention. The clinical team sought to evaluate alternative combination therapies through a literature review. Elicit, an AI-powered research assistant, was employed to structure the literature review process through an automated analysis of scientific papers. This case served as a test of Elicit's capabilities in synthesizing treatment options for rare cancers, compared to traditional research methodologies. The platform demonstrated significant limitations in its search capabilities due to restricted database access. However, it showed efficiency in analyzing provided papers and organizing clinical data by key categories. These findings suggest that while Elicit may serve as a helpful support tool for literature analysis, it is best used as a complement to traditional search methods, with careful verification of its output by clinical experts. Disclosures: Dolev Vaknin, Or Degany, Rotem Sisso-Avron, and Prof. Sharon Einav are employed by Medint Medical Intelligence, which conducted the literature review that served as the basis for this paper.","PeriodicalId":101459,"journal":{"name":"Harefuah","volume":"164 5","pages":"281-284"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144145322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[OSGOOD-SCHLATTER DISEASE: DIAGNOSIS AND MANAGEMENT]. [奥斯古德-舒特病：诊断与治疗]。

Harefuah Pub Date : 2025-05-01

Raphael Israeli, Dana Avraham, Amir Herman, Lev Lapidos, Maria Oulianski

引用次数: 0

[The Pain of Compassion Fatigue]. [同情疲劳的痛苦]。

Harefuah Pub Date : 2025-05-01

Joshua Shemer

引用次数: 0

[TENNIS ELBOW]. (网球肘)。

Harefuah Pub Date : 2025-05-01

Ruth Luttwak, Gershon Zinger