Vijay Kumar, Vikas Sharma, Sandhya Pandey, Uma Shankar Pal
{"title":"Radiation effects in head and neck and role of hyperbaric oxygen therapy: An adjunct to management.","authors":"Vijay Kumar, Vikas Sharma, Sandhya Pandey, Uma Shankar Pal","doi":"10.4103/njms.njms_185_23","DOIUrl":"10.4103/njms.njms_185_23","url":null,"abstract":"<p><strong>Background: </strong>Radiotherapy is considered an essential treatment modality in cancers, especially head and neck cancers. Radiotherapy can be given as a definitive, supportive, or adjuvant therapy for various cancers. Radiation damage is an avoidable complication in many patients, after or during radiotherapy. It may be either dose-related, duration-related, or frequency-related. The effects of radiation damage are mainly caused by ischemic necrosis, and once settled it is difficult to manage due to the low vascularity of the affected area.</p><p><strong>Aim: </strong>To find out the effectiveness of hyperbaric oxygen therapy (HBOT) in the management of radiation damage in the head and neck region.</p><p><strong>Materials and methods: </strong>Retrospective data of patients attending the HBOT clinic for postradiotherapy changes were recorded in an Excel sheet and analyzed in this study. Statistical analysis was done.</p><p><strong>Result: </strong>Our study showed that HBOT is effective in postradiation trismus, xerostomia, discharge, foul smell, discharging sinus, etc., However, it was not found to be significant in the closure of fistula with exposed bone.</p><p><strong>Conclusion: </strong>HBOT is an effective adjunct modality for the management of postradiation changes in the head and neck region.</p>","PeriodicalId":101444,"journal":{"name":"National journal of maxillofacial surgery","volume":"15 2","pages":"220-227"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11371294/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142134990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Navin Singh, Akhilanand Chaurasia, Akhilesh Kumar Singh, Anshul Agarwal, Aida Nur Ashikin Binti Abd Rahman, Rini Tiwari
{"title":"Volumetric analysis of mastoid air cells in orthodontic malocclusions in 3D cone beam computed tomography (CBCT).","authors":"Navin Singh, Akhilanand Chaurasia, Akhilesh Kumar Singh, Anshul Agarwal, Aida Nur Ashikin Binti Abd Rahman, Rini Tiwari","doi":"10.4103/njms.njms_153_22","DOIUrl":"10.4103/njms.njms_153_22","url":null,"abstract":"<p><strong>Objectives: </strong>To determine age- and sex-related changes in mastoid air cells volume in orthodontic malocclusions (class 1, class 2, class 3) in cone beam computed tomography (CBCT), morphometric analysis, and age prediction on the basis of mastoid air cells.</p><p><strong>Methods: </strong>In total, 150 3D CBCT scans of study subjects having class 1, class 2, and class 3 malocclusions have been analyzed retrospectively for the estimation of volume of mastoid air cells by Dolphin imaging software V11.9, and measurement data of volumes have been recorded and analyzed using SPSS software 24.v.</p><p><strong>Results: </strong>The volume of mastoid air cells was highest in age group of 14-28 years which was statistically not significant (P value >.05). The volume of mastoid air cells in the right side of cranium is greater than mastoid air cells in the left side. The mastoid air cell volume was higher in males than females. The volume of mastoid air cells (right side) was highest in class II malocclusion (2404.53 ± 1737.50 mm<sup>3</sup>) followed by class III and was least in class I malocclusion (1842.09 ± 1263.78 mm<sup>3</sup>). However, the volume of mastoid air cells in the left side was highest in class III malocclusion (2368.03 ± 1853.00 mm<sup>3</sup>) followed by class II and was least in class I (1920.52 ± 1285.34 mm<sup>3</sup>).</p><p><strong>Conclusions: </strong>The volume of mastoid air cells varies in different class of orthodontic malocclusions. The mastoid air cells volume is higher in males than females. On the basis of mastoid air cells volume, we are able to predict the age, sex, and class of orthodontic malocclusion.</p>","PeriodicalId":101444,"journal":{"name":"National journal of maxillofacial surgery","volume":"15 2","pages":"278-282"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11371290/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142134993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparative evaluation of salivary, serum, and GCF alkaline phosphatase levels in chronic periodontitis patients before and after nonsurgical periodontal therapy: A clinico-biochemical study.","authors":"Sarita Parihar, Preeti Singh, Ragini Srivastava, Atul Srivastava, Fouzia Imran, J P Vishnu","doi":"10.4103/njms.njms_53_23","DOIUrl":"10.4103/njms.njms_53_23","url":null,"abstract":"<p><strong>Background: </strong>Chronic periodontitis is a multifactorial disease that causes the supporting tissues around the teeth to become inflamed and destroyed, which further causes tooth mobility and eventual tooth loss. The enzyme alkaline phosphatase (ALP), which is involved in bone resorption and gingival inflammation, is an important biomarker. The current study's objective is to compare the serum, gingival crevicular fluid (GCF), and salivary levels of ALP in individuals with chronic periodontitis before and after nonsurgical periodontal therapy.</p><p><strong>Materials and methods: </strong>On the basis of clinical and radiographic examinations, 72 participants were split into two groups: Group I (healthy individuals) and Group II (chronic periodontitis patients). All patients who were in an aseptic condition had their serum, GCF, and unstimulated saliva taken, and samples were then tested for ALP levels using ALP kit.</p><p><strong>Results: </strong>The difference in salivary, serum, and GCF ALP levels between the control group (23.44 ± 4.76, 58.88 ± 8.29, and 776.76 ± 121.91) and the study group (105.66 ± 16.33, 102.38 ± 4.43, and 1,825.77 ± 275.12) was found to be statistically significant with <i>P</i> < 0.001. The difference in salivary, serum, and GCF ALP levels from baseline (105.66 ± 16.33, 102.38 ± 4.43, and 1,825.77 ± 275.12) to postoperative (49.54 ± 5.69, 83.46 ± 4.22, and 1,148.38 ± 129.01) was found to be statistically significant with <i>P</i> < 0.001. The results demonstrated that patients with chronic periodontitis have considerably higher levels of serum, GCF, and salivary ALP than healthy individuals.</p><p><strong>Conclusion: </strong>Salivary and GCF ALP can thus be used as a key inflammatory diagnostic biomarker in periodontal diseases.</p>","PeriodicalId":101444,"journal":{"name":"National journal of maxillofacial surgery","volume":"15 2","pages":"262-267"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11371287/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142135055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Reza Tabrizi, Pegah Mehrabi, Shervin Shafiei, Amir Azimi, Hamidreza Moslemi
{"title":"Does crown-to-implant ratio affect marginal bone loss around a single short implant at the posterior of the mandible?","authors":"Reza Tabrizi, Pegah Mehrabi, Shervin Shafiei, Amir Azimi, Hamidreza Moslemi","doi":"10.4103/njms.njms_27_23","DOIUrl":"10.4103/njms.njms_27_23","url":null,"abstract":"<p><strong>Context: </strong>Short implants are acceptable treatment options for atrophic ridges; however, they increase the crown-to-implant (C/I) ratio compared to regular length implants. The study aimed to assess the correlation between the C/I ratio and marginal bone loss (MBL) in single short implants at the posterior of the mandible.</p><p><strong>Aims: </strong>The study aimed to assess the correlation between the C/I ratio and MBL in single short implants at the posterior of the mandible.</p><p><strong>Settings and design: </strong>Cross-sectional study.</p><p><strong>Materials and methods: </strong>This cross-sectional study assessed short implants with 6 mm lengths at the posterior of the mandible. The long-cone peri-apical digital radiographs were taken immediately after loading and 24 months later. Age, gender, implant diameter, gingival biotype, and implant brands were the study variables, and the C/I ratio was the predictive factor. The mean MBL at 2 years was considered the study outcome.</p><p><strong>Statistical analysis used: </strong>The Pearson correlation test was applied to assess the correlation between MBL and C/I.</p><p><strong>Results: </strong>Seventy implants (36 Straumann and 34 SGS implants) were studied. A significant difference was observed in the mean MBL between the two implant brands (<i>P</i> < 0.001). Besides, a correlation was found between MBL and the C/I ratio (<i>P</i> = 0.002).</p><p><strong>Conclusions: </strong>It seems that the C/I ratio is associated with an MBL increase in single short implants at the posterior of the mandible.</p>","PeriodicalId":101444,"journal":{"name":"National journal of maxillofacial surgery","volume":"15 2","pages":"273-277"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11371288/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142135060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Estimating the magnitude of different barriers to dental care for special needs patients: A systematic review.","authors":"Bhaskar Agarwal, Shitij Srivastava, Abhinav Shekhar, Kshitij Arora, Mayank Singh, Lakshya Kumar","doi":"10.4103/njms.njms_206_22","DOIUrl":"10.4103/njms.njms_206_22","url":null,"abstract":"<p><p>Quite often, it is seen that the number of special care individual in the dental OPD/clinics is quite low, as compared to their population. This can be due to specific barriers that restrict them in availing dental treatment. Our aim was to identify different barriers to dental care of persons with special needs through a systematic review and to quantify them. A systematic review was carried out according to PRISMA guidelines. PubMed data was searched with predefined keywords leading to retrieval of 576 records. Full length studies published in English language from 2010 onwards with mention of proportion of persons citing a barrier to dental care were included. Three studies published in peer reviewed journals from other data sources were also identified while retrieving the full length texts. Out of a total of 576 PubMed and three additional records, a total of 22 studies were included in the systematic review. Cost, communication, physical facilities, fear/uncooperativeness, unawareness, distant location/inaccessibility, unwilling dentist, transportation, and difficulty in getting appointment were identified as nine major barriers. Pooled proportions for different barriers ranged from 22.75% (Accessibility; 95%CI = 19.96-25.54) to 44.35% (Communication; 95% CI = 32.63-56.07A). There was a high heterogeneity across different studies for both fixed effects and random effects models. Communication, physical facilities, and unawareness were identified as the three most common barriers showing minimum heterogeneity in random effects model.</p>","PeriodicalId":101444,"journal":{"name":"National journal of maxillofacial surgery","volume":"15 2","pages":"188-198"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11371300/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142135064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Healing of periosteal pedicle graft in the treatment of gingival recession defects: A histological study in rabbits.","authors":"Asi Kanwarjit Singh, Ajay Mahajan, Deepa Rayast","doi":"10.4103/njms.njms_187_22","DOIUrl":"10.4103/njms.njms_187_22","url":null,"abstract":"<p><strong>Purpose: </strong>Various surgical techniques are described in the literature to manage gingival recession defects but the histopathologic evidence to support the current available techniques, is scarce. Recently periosteal pedicle graft (PPG) has proven to be an effective treatment option to treat gingival recession defects (GRD) with results comparable to subepithelial connective tissue graft (SCTG).</p><p><strong>Objective: </strong>The present histopathological study was done to evaluate the healing pattern of periosteal pedicle autogenous graft along with coronally advanced flap in the treatment of gingival recession defects.</p><p><strong>Materials and methods: </strong>The present study was performed on 10 sites in 5 rabbits. Two sites were selected in each animal and gingival recession defects were surgically created and then treated using periosteal pedicle pedicle graft along with coronally advanced flap procedure. Healing pattern was assessed histopathologically at pre-defined intervals till 6 months.</p><p><strong>Results: </strong>On the 7th day of healing, dilated blood vessels with inflammatory cells were seen, while rudimentary rete-pegs appeared on 14th day. Between 3 months to 6 months, advanced histological repair with connective tissue organization with initiation of junctional epithelium, cementum and bone formation were observed.</p><p><strong>Conclusion: </strong>Gingival recession defects treated with PPG had evidences of regeneration of cementum, bone and periodontal ligament fibers with new connective tissue attachment.</p>","PeriodicalId":101444,"journal":{"name":"National journal of maxillofacial surgery","volume":"15 2","pages":"283-287"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11371282/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142135066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"New induction chemotherapy using intra-arterial infusion for tongue squamous cell carcinoma to avoid reconstructive surgery: A 6 case reports.","authors":"Tetsuharu Kaneko, Chihiro Kanno, Morio Yamazaki, Sadanoshin Yaginuma","doi":"10.4103/njms.njms_14_24","DOIUrl":"10.4103/njms.njms_14_24","url":null,"abstract":"<p><p>Most tongue squamous cell carcinoma (TSCC) classified as T3 require reconstructive surgery, which inevitably causes problems with oral functions. We propose new induction chemotherapy using intra-arterial infusion for TSCC classified as T3 to avoid reconstructive surgery. This chemotherapy regimen consists of intra-arterial infusion of docetaxel and cisplatin and systemic administration of 5-fluorouracil. As a result of this treatment, the therapeutic effect was a complete response in five patients and a partial response in one patient, and the overall response rate was 100%. All six patients underwent partial resection because their tumors shrank with this induction chemotherapy. In addition, adverse events of grade 3 or more did not occur in all six patients. The median follow-up duration for all patients was 34 months, and they are alive. This intra-arterial chemotherapy regimen was shown to be highly efficacious and safe.</p>","PeriodicalId":101444,"journal":{"name":"National journal of maxillofacial surgery","volume":"15 2","pages":"316-318"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11371285/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142135068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Breast cancer metastasizing to salivary glands: Systematic review.","authors":"Sonia Gupta, Mayur Manoharrao Shingade, Manasi Pangarkar, Annie Evangelin Nithiakumar, Pallavi Sharma, Nausheen Aga, Kinza Qureshi, Muna Eisa Mohamed Hassan, Achla Bharti Yadav","doi":"10.4103/njms.njms_80_23","DOIUrl":"10.4103/njms.njms_80_23","url":null,"abstract":"<p><p>Distant metastasis to salivary glands is a very rare event and most often associated with primary malignancies of the skin. Only 1-4% of all salivary gland tumours manifest with metastasis. Carcinomas of the breast, lung, kidney and prostate are those primaries that may also potentially metastasize to salivary glands. Literature has documented several studies analysing metastatic tumours in the oral region. However, very little research work has been published to date to analyse solely the Breast cancer metastasizing to the salivary glands. Thus, this review was conducted to examine the published cases of Breast cancer metastasizing to salivary glands from March 1975 to March 2023. An electronic search of the published literature was performed without publication year limitation in PubMed/ Medline, Scopus, Google Scholar, Web of Science, Science Direct, Embase, and Research Gate databases, using mesh keywords like ('Breast cancer' OR 'Breast carcinoma') AND ('Metastasis' OR 'Metastases'), And ('Salivary glands' OR 'Parotid gland' OR 'Submandibular gland' OR 'Sublingual gland'). We also searched all related journals manually. The reference list of all articles was also checked. Our research revealed a total of 48 relevant papers with 55 patients. Parotid was the most predominantly affected salivary gland. 14.5% of patients died with a mean survival time of 7 months. It can be concluded from this research that Breast cancer metastasizing to salivary glands is a rare occurrence. Careful evaluation of these cases is needed in order to raise awareness of these lesions and gain a better understanding of their characteristics.</p>","PeriodicalId":101444,"journal":{"name":"National journal of maxillofacial surgery","volume":"15 2","pages":"199-207"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11371303/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142135053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pooja Priyadarshini, Deepak Singh, Vipul Kumar Sharma, T P Chaturvedi, Akhilesh Kumar Singh
{"title":"Effect of mandibular advancement therapy on inflammatory biomarkers in obstructive sleep apnea: A systematic review.","authors":"Pooja Priyadarshini, Deepak Singh, Vipul Kumar Sharma, T P Chaturvedi, Akhilesh Kumar Singh","doi":"10.4103/njms.njms_79_22","DOIUrl":"10.4103/njms.njms_79_22","url":null,"abstract":"<p><p>To review the literature on the effect of mandibular advancement therapy (MAT) on inflammatory biomarkers in obstructive sleep apnea (OSA). The present systematic review addresses the following focus question: What is the effect of MAT on inflammatory biomarkers in OSA? Electronic and manual literature searches were conducted on databases: PubMed/MEDLINE, Web of Science, and Cochrane Library for studies published until September 2021 to collect information about the effect of mandibular advancement therapy, a non-continuous positive airway pressure alternative measurement of OSA. A systematic literature review was performed following the PRISMA guidelines to identify studies evaluating the effect of MAT in patients suffering from OSA. Randomized clinical trials were included, and case reports, retrospective studies, literature reviews, <i>in-vitro</i> studies, observational studies, authors' opinions, letters to the editor, and engineering articles were excluded. Fifty-nine articles published before September 2021 were identified. Fifty-four articles met the inclusion criteria. After assessing inclusion criteria, three clinical trials were included with 148 patients suffering from OSA and treated with mandibular advancement therapy. The follow-up period ranged from two to three months, with the average follow-up being 1.66 months. The mean age of the patients was observed to be 53.11 ± 2.65 years. The mean Epworth Sleepiness Scale observed in patients in all three clinical trials was 9.75 ± 0.89. MAT in patients with moderate or severe OSA reduced apnea-hypopnea index but has less effect on inflammatory and metabolic biomarkers.</p>","PeriodicalId":101444,"journal":{"name":"National journal of maxillofacial surgery","volume":"15 2","pages":"177-182"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11371302/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142135062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abhay N Datarkar, Arwa F Pardiwala, Priyanka Relan, Surendra Daware, Vandana Gadve, Archana Deshpande, Ashlesha Ghormade
{"title":"A 3-Dimensional finite element analysis of patient-specific implant (with strut abutments) interface on stress concentration on the implant and surrounding bone in bilateral maxillary deformities.","authors":"Abhay N Datarkar, Arwa F Pardiwala, Priyanka Relan, Surendra Daware, Vandana Gadve, Archana Deshpande, Ashlesha Ghormade","doi":"10.4103/njms.njms_155_23","DOIUrl":"10.4103/njms.njms_155_23","url":null,"abstract":"<p><strong>Purpose: </strong>To determine the efficacy and longevity of patient-specific implants (PSIs) with strut abutment design to rehabilitate bilateral maxillectomy defect.</p><p><strong>Materials and methods: </strong>Finite Element Analysis was performed on a PSI with strut abutments to repair a patient's bilateral maxillectomy defect due to COVID associated mucormycosis.</p><p><strong>Results: </strong>The von Mises stress recorded was maximum in the zygomaticomaxillary buttress region, and displacement values were noted to be highest in the posterior-most strut, although both parameters were within acceptable limits, which is favorable.</p><p><strong>Conclusion: </strong>The authors draw the conclusion that a PSI with strut abutments is a workable therapeutic modality for patients with these kinds of abnormalities based on this information.</p>","PeriodicalId":101444,"journal":{"name":"National journal of maxillofacial surgery","volume":"15 2","pages":"268-272"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11371289/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142135108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}