Spanish Journal of Psychiatry and Mental Health最新文献

{"title":"Risk factors for suicidal behavior in late life: Clinical relevance.","authors":"Veronica Fernandez-Rodrigues, Marina Diaz-Marsa, Jorge Andreo-Jover, Wala Ayad-Ahmed, Mª Teresa Bobes-Bascarán, María-Ángeles Botí, Manuel Canal-Ribero, Ana Isabel Cebria Meca, Benedicto Crespo-Facorro, Alejandro de la Torre-Luque, Sandra Doval, Matilde Elices, Adriana Garcia-Ramos, Ana Gonzalez-Pinto, Iria Grande, Gonzalo Hervas, Luis Jiménez-Treviño, Guillermo Juarez, Angela Palao-Tarrero, Diego J Palao Vidal, Natalia Roberto, Pilar Alejandra Sáiz, Miguel Ruiz Veguilla, Victor Perez-Sola","doi":"10.1016/j.sjpmh.2025.11.001","DOIUrl":"10.1016/j.sjpmh.2025.11.001","url":null,"abstract":"<p><strong>Background: </strong>Suicide is a leading cause of mortality worldwide, with approximately 27% of deaths by suicide occurring in individuals older than 70 years. Suicide attempts in older adults are more likely to be fatal and are typically more premeditated than impulsive. The objective of this study was to identify key sociodemographic and clinical characteristics of older adults who recently attempted suicide.</p><p><strong>Material and methods: </strong>The total sample included 1336 adult patients, categorized into 3 groups (young, middle-aged, and elderly group), who had attended the emergency room with a suicide attempt. An analysis was performed using Chi-square tests and ANOVA for risk factors, to study the relationships among suicidal ideation, behavior, psychiatric symptoms, impulsivity and childhood trauma. Similarly, to compare inter-group risk factors and suicidal behavior, multigroup path analysis was used.</p><p><strong>Results: </strong>The older group stood out in lower levels of suicidal ideation, self-harm, trauma and impulsivity. Similarly, they showed higher levels of hypermentalization, greater medical damage after the suicide attempt and fewer psychiatric diagnoses, than the patients from the other age groups.</p><p><strong>Conclusions: </strong>Although older people have fewer clinical symptoms and risk factors, their attempts are more severe. Preventing suicide in older people is complex, being a very vulnerable period, where there are unique risk factors, making it necessary to develop new effective interventions to prevent suicide in this neglected population.</p>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145727920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical management recommendations for adults with attention-deficit/hyperactivity disorder.","authors":"Josep Antoni Ramos-Quiroga, Elena Benítez Cerezo, María Del Juncal Sevilla, José Martínez-Raga, Javier Quintero","doi":"10.1016/j.sjpmh.2025.10.003","DOIUrl":"10.1016/j.sjpmh.2025.10.003","url":null,"abstract":"<p><strong>Introduction: </strong>Attention-deficit/hyperactivity disorder (ADHD) is a common, complex, multifactorial neurodevelopmental disorder. In this study, conducted by experts in the management of ADHD in adults, a set of recommendations have been developed based on a review of the available evidence, with the aim of improving the clinical care of these patients.</p><p><strong>Materials and methods: </strong>This study was conducted in full compliance with the consensus methodology developed by the RAND Corporation/University of California Los Angeles (RAND/UCLA). The 29 proposed statements were evaluated using a 2-round iterative Delphi process. Of the 18 invited panellists, 15 completed both rounds (83.3% response rate).</p><p><strong>Results: </strong>After 2 rounds of voting, the expert panel reached consensus, either in agreement or disagreement, on 93.1% of the statements (a total of 27 of the 29 proposed). These included proposals on important topics in the management of ADHD in adults, such as barriers to detection and diagnosis, unmet treatment needs, treatment objectives, the treat-to-target approach, and response and remission criteria.</p><p><strong>Conclusions: </strong>This study has sought to reinforce the importance of a structured and multidisciplinary approach in the management of ADHD in adulthood, focused on the patient and their needs. The recommendations presented here aim not only to mitigate the adverse outcomes associated with untreated ADHD, but also to facilitate a substantial improvement in the quality of life of individuals living with this disorder.</p>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145703514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond glory: Psychological and physical trauma among soldiers of the Spanish Tercios.","authors":"Fernando Espí Forcén","doi":"10.1016/j.sjpmh.2025.09.003","DOIUrl":"10.1016/j.sjpmh.2025.09.003","url":null,"abstract":"","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145566534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Suicide rates in the Guardia Civil corps: An updated analysis based on 39 years of data.","authors":"Lucas Giner, Sergio Sanz-Gómez, Adelo Manuel Moya-Fernández, Benito José Florido-Vera, Adrián Alacreu-Crespo, Julio Guija","doi":"10.1016/j.sjpmh.2025.07.006","DOIUrl":"10.1016/j.sjpmh.2025.07.006","url":null,"abstract":"","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145544950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of motivation in schizophrenia: Patient- and clinician-rated outcomes.","authors":"Emilio Fernandez-Egea, Gabriel Robert, Anna Mane, Michel Sabe, Noemie Kuenzi, Mariia Kaliuzhna, Fabien Carruzzo, Fiona Diniel, Anne Julie Riclet, Laura Martinez-Sadurni, Elif Ates Budak, Bruno Giordana, Paola Bucci, Giula Maria Giordano, Luigi Giuliani, Peter B Jones, Dominque Drapier, Silvana Galderisi, Philippe Robert, Stefan Kaiser, Noham Wolpe, Armida Mucci","doi":"10.1016/j.sjpmh.2025.08.001","DOIUrl":"10.1016/j.sjpmh.2025.08.001","url":null,"abstract":"<p><strong>Introduction: </strong>Negative symptoms, such as apathy and diminished motivation, are critical for prognosis and treatment outcomes in neurological and psychiatric disorders. However, constructs and assessment scales differ significantly across neuropsychiatric disorders. This study examines the psychometric properties of two scales used to assess apathy - the apathy-motivation index (AMI) and the diagnostic criteria for apathy (DCA) - compared to schizophrenia-specific tools, namely the brief negative symptoms scale (BNSS) and the positive and negative syndrome scale (PANSS).</p><p><strong>Methods: </strong>We conducted a cross-sectional, multicenter study with 151 individuals with schizophrenia across six European sites. Participants were assessed using the AMI, DCA, BNSS, PANSS, and other clinical and functional scales. BNSS motivation and pleasure factor (BNSS_MAP) assessed motivation, and personal and social performance (PSP) assessed functioning. Convergent validity across these tools was examined through bivariate correlations (Pearson r) and exploratory factor analysis for the AMI. Cut-off points for apathy used receiver operating characteristic (ROC) analysis, with DCA as the reference.</p><p><strong>Results: </strong>We found low convergence between BNSS_MAP and AMI (r=.31, p<.001) and moderate convergence between BNSS_MAP and DCA (r=.48, p<.001). PSP correlated with BNSS_MAP, PANSS_negative and DCA (r=-.615, r=-.446 and r=-.430, respectively, all p<0.001), but not with AMI (r=-.108; p=.218). ROC analysis yielded cut-off points of 28.5 (BNSS total), 16.5 (BNSS_MAP), 14.5 (PANSS_negative), and 33.5 (AMI total) for detecting clinical apathy.</p><p><strong>Conclusion: </strong>Current apathy and motivation scales show limited overlap, reflecting the complexity of measuring transdiagnostic constructs. Combining clinician- and patient-rated measures may provide a more comprehensive understanding of apathy in schizophrenia and other neuropsychiatric conditions.</p>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145544981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Volume alterations of the hippocampus and amygdala in patients with schizophrenia and persistent auditory hallucinations","authors":"Marta Perez-Rando ,&nbsp;Carlota Penades-Gomiz ,&nbsp;Pablo Martinez-Marin ,&nbsp;Gracián García-Martí ,&nbsp;Eduardo J. Aguilar ,&nbsp;Maria J. Escarti ,&nbsp;Eva Grasa ,&nbsp;Iluminada Corripio ,&nbsp;Julio Sanjuan ,&nbsp;Juan Nacher","doi":"10.1016/j.rpsm.2023.05.002","DOIUrl":"10.1016/j.rpsm.2023.05.002","url":null,"abstract":"<div><h3>Introduction</h3><div>Auditory hallucinations (AH) are one of the most prevalent symptoms of schizophrenia. They might cause several brain alterations, especially changes in the volumes of hippocampus and amygdala, regions related to the relay and processing of auditory cues and emotional memories.</div></div><div><h3>Material and methods</h3><div>We have recruited 41 patients with schizophrenia and persistent AH, 35 patients without AH, and 55 healthy controls. Using their MRIs, we have performed semiautomatic segmentations of the hippocampus and amygdala using Freesurfer. We have also performed bilateral correlations between the total PSYRATS score and the volumes of affected subregions and nuclei.</div></div><div><h3>Results</h3><div>In the hippocampus, we found bilateral increases in the volume of its hippocampal fissure and decreases in the right fimbria in patients with and without AH. The volume of the right hippocampal tail and left head of the granule cell layer from the dentate gyrus were decreased in patients with AH. In the amygdala, we found its left total volume was shrunk, and there was a decrease of its left accessory basal nucleus in patients with AH.</div></div><div><h3>Conclusions</h3><div>We have detected volume alterations of different limbic structures likely due to the presence of AH. The volumes of the right hippocampal tail and left head of the granule cell layer from the dentate gyrus, and total volume of the amygdala and its accessory basal nucleus, were only affected in patients with AH. Bilateral volume alterations in the hippocampal fissure and right fimbria seem inherent of schizophrenia and due to traits not contemplated in our research.</div></div>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":"18 4","pages":"Pages 241-249"},"PeriodicalIF":2.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9876563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From biomarkers to care: integrating biology and clinical translation in psychiatry","authors":"Javier Labad","doi":"10.1016/j.sjpmh.2025.12.001","DOIUrl":"10.1016/j.sjpmh.2025.12.001","url":null,"abstract":"","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":"18 4","pages":"Pages 229-230"},"PeriodicalIF":2.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145799783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment and the concept of negative symptoms","authors":"Brian Kirkpatrick ,&nbsp;Emilio Fernandez-Egea","doi":"10.1016/j.sjpmh.2023.09.006","DOIUrl":"10.1016/j.sjpmh.2023.09.006","url":null,"abstract":"","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":"18 4","pages":"Pages 231-233"},"PeriodicalIF":2.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136153969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Altered activation of the dorsal anterior cingulate cortex during oddball performance in individuals at risk for Alzheimer's disease","authors":"Pamela Chavarría-Elizondo ,&nbsp;Carla del Río-Torné ,&nbsp;Pablo Maturana-Quijada ,&nbsp;Ignacio Martínez-Zalacaín ,&nbsp;Asier Juaneda ,&nbsp;Inés del Cerro ,&nbsp;Andrés Guinea-Izquierdo ,&nbsp;Jordi Gascón-Bayarri ,&nbsp;Ramón Reñé-Ramírez ,&nbsp;Mikel Urretavizcaya ,&nbsp;Isidre Ferrer ,&nbsp;José M. Menchón ,&nbsp;Virginia Soria ,&nbsp;Carles Soriano-Mas","doi":"10.1016/j.sjpmh.2024.07.001","DOIUrl":"10.1016/j.sjpmh.2024.07.001","url":null,"abstract":"<div><h3>Introduction</h3><div>The neural mechanisms underlying neurodegenerative disorders in the elderly remain elusive, despite extensive neuroimaging research in recent decades. Amnestic type mild cognitive impairment (aMCI) and late-life major depressive disorder (MDD) are two such conditions characterized by intersecting cognitive and affective symptomatology, and they are at a higher risk for Alzheimer's disease.</div></div><div><h3>Materials and methods</h3><div>This study analyzed the neural underpinnings of cognitive and depressive symptoms in a cohort comprising 12 aMCI subjects, 24 late-life MDD patients, and 26 healthy controls (HCs). Participants underwent a detailed neuropsychological assessment and completed a visual attentional oddball task during functional magnetic resonance imaging (fMRI), with evaluations at baseline and at 2-year follow-up.</div></div><div><h3>Results</h3><div>Initial findings showed that aMCI subjects had reduced dACC activation during oddball (target) stimulus detection, a pattern that persisted in longitudinal analyses and correlated with cognitive functioning measures. For HCs, subsequent dACC activation was linked to depression scores. Furthermore, in the affective-cognitive altered groups, later dACC activation correlated with oddball and memory performance.</div></div><div><h3>Conclusions</h3><div>These findings enhance our comprehension of the neurobiological basis of cognitive and depressive disturbances in aging, indicating that dACC activation in response to a visual attentional oddball task could serve as a neural marker for assessing cognitive impairment and depression in conditions predisposing to Alzheimer's disease.</div></div>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":"18 4","pages":"Pages 274-280"},"PeriodicalIF":2.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141592544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The influence of reward sensitivity on weight in treatment-resistant chronic schizophrenia","authors":"Isaac Jarratt Barnham ,&nbsp;Youssuf Saleh ,&nbsp;Masud Hussain ,&nbsp;Emilio Fernandez-Egea","doi":"10.1016/j.sjpmh.2024.01.005","DOIUrl":"10.1016/j.sjpmh.2024.01.005","url":null,"abstract":"","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":"18 4","pages":"Pages 288-289"},"PeriodicalIF":2.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139708941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}