Yolanda Sánchez-Carro, Alejandro de la Torre-Luque, Marina Díaz-Marsá, Raimundo Aguayo-Estremera, Jorge Andreo-Jover, Wala Ayad-Ahmed, Julio Bobes, Teresa Bobes-Bascarán, María Fé Bravo-Ortiz, Manuel Canal-Rivero, Ana Isabel Cebrià, Benedicto Crespo-Facorro, Matilde Elices, Verónica Fernández-Rodrigues, Purificacion Lopez-Peña, Iría Grande, Ángela Palao-Tarrero, Andrés Pemau, Natalia Roberto, Miguel Ruiz-Veguilla, Víctor Pérez-Solà
{"title":"Psychiatric profiles in suicidal attempters: Relationships with suicide behaviour features.","authors":"Yolanda Sánchez-Carro, Alejandro de la Torre-Luque, Marina Díaz-Marsá, Raimundo Aguayo-Estremera, Jorge Andreo-Jover, Wala Ayad-Ahmed, Julio Bobes, Teresa Bobes-Bascarán, María Fé Bravo-Ortiz, Manuel Canal-Rivero, Ana Isabel Cebrià, Benedicto Crespo-Facorro, Matilde Elices, Verónica Fernández-Rodrigues, Purificacion Lopez-Peña, Iría Grande, Ángela Palao-Tarrero, Andrés Pemau, Natalia Roberto, Miguel Ruiz-Veguilla, Víctor Pérez-Solà","doi":"10.1016/j.sjpmh.2024.01.004","DOIUrl":"10.1016/j.sjpmh.2024.01.004","url":null,"abstract":"<p><strong>Background: </strong>Suicide constitutes a major health concern worldwide, being a significant contributor of death, globally. The diagnosis of a mental disorder has been extensively linked to the varying forms of suicidal ideation and behaviour. The aim of our study was to identify the varying diagnostic profiles in a sample of suicide attempters.</p><p><strong>Methods: </strong>A sample of 683 adults (71.3% females, 40.10±15.74 years) admitted at a hospital emergency department due to a suicide attempt was recruited. Latent class analysis was used to identify diagnostic profiles and logistic regression to study the relationship between comorbidity profile membership and sociodemographic and clinical variables.</p><p><strong>Results: </strong>Two comorbidity profiles were identified (Class I: low comorbidity class, 71.3% of attempters; Class II: high comorbidity class, 28.7% of attempters). Class I members were featured by the diagnosis of depression and general anxiety disorder, and low comorbidity; by contrast, the high comorbidity profile was characterized by a higher probability of presenting two or more coexisting psychiatric disorders. Class II included more females, younger, with more depressive symptoms and with higher impulsivity levels. Moreover, Class II members showed more severe suicidal ideation, higher number of suicide behaviours and a greater number of previous suicide attempts (p<.01, for all the outcomes), compared to Class I members.</p><p><strong>Conclusions: </strong>Psychiatric profiles may be considered for treatment provision and personalized psychiatric treatment in suicidal attempters as well as tackle suicide risk.</p>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139708962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alicia García-Alcón , Javier González-Peñas , María José Penzol , Diego Gerez , Mónica Burdeus , Elisa Weckx , Álvaro Andreu-Bernabeu , Carmen Moreno , Mara Parellada
{"title":"An exploratory analysis of parental autism traits, age at conception and polygenic background in Autism Spectrum Disorders","authors":"Alicia García-Alcón , Javier González-Peñas , María José Penzol , Diego Gerez , Mónica Burdeus , Elisa Weckx , Álvaro Andreu-Bernabeu , Carmen Moreno , Mara Parellada","doi":"10.1016/j.rpsm.2021.12.001","DOIUrl":"10.1016/j.rpsm.2021.12.001","url":null,"abstract":"<div><h3>Introduction</h3><p>Advanced parental age (APA) has been associated with an increased risk for autism in the offspring. One explanatory model includes delayed fatherhood in parents with autistic traits.</p></div><div><h3>Material and methods</h3><p>We investigated (1) whether autistic traits in parents, evaluated with the Autism-spectrum Quotient (AQ), correlate with APA in 128 families, (2) in 83 trios with genetic data available, whether AQ correlated with polygenic vulnerability calculated by Polygenic Risk Scores (PRS). We stratified the analyses by as per DSM-IV autism subtypes and by parental sex.</p></div><div><h3>Results</h3><p>We found a statistically significant relation between AQ and APA (<em>r</em> <!-->=<!--> <!-->0.207, <em>p</em> <!-->=<!--> <!-->8.39<!--> <!-->×<!--> <!-->10<sup>−4</sup>, <em>n</em> <!-->=<!--> <!-->256), significantly only in mothers (<em>r</em> <!-->=<!--> <!-->0.233, <em>p</em> <!-->=<!--> <!-->8.23<!--> <!-->×<!--> <!-->10<sup>−3</sup>, <em>n</em> <!-->=<!--> <!-->128) and in Asperger Syndrome (AS) (<em>r</em> <!-->=<!--> <!-->0.319, <em>p</em> <!-->=<!--> <!-->0.034, <em>n</em> <!-->=<!--> <!-->44). There was a significant association between PRS and AQ in the mothers of the participants with AS (β (95%CI)<!--> <!-->=<!--> <!-->3.28 (0.03–6.59); <em>p</em> <!-->=<!--> <!-->0.047).</p></div><div><h3>Conclusions</h3><p>These results show that, in this sample, older mothers present more autistic traits, and APA seems to relate to an AS profile. Furthermore, PRS is significantly associated with maternal AQ of AS subjects. Consequently, a higher polygenic maternal contribution (both by AQ and PRS) seems to contribute to an AS profile.</p></div>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":"17 1","pages":"Pages 28-34"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1888989121001312/pdfft?md5=dfad4be45cd835ee58c1c951e5603112&pid=1-s2.0-S1888989121001312-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74611328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eduardo Fonseca-Pedrero , Adriana Díez-Gómez , Usue de la Barrera , Carla Sebastian-Enesco , Javier Ortuño-Sierra , Inmaculada Montoya-Castilla , Beatriz Lucas-Molina , Félix Inchausti , Alicia Pérez-Albéniz
{"title":"Suicidal behaviour in adolescents: A network analysis","authors":"Eduardo Fonseca-Pedrero , Adriana Díez-Gómez , Usue de la Barrera , Carla Sebastian-Enesco , Javier Ortuño-Sierra , Inmaculada Montoya-Castilla , Beatriz Lucas-Molina , Félix Inchausti , Alicia Pérez-Albéniz","doi":"10.1016/j.rpsm.2020.04.007","DOIUrl":"10.1016/j.rpsm.2020.04.007","url":null,"abstract":"<div><h3>Objective</h3><p>Suicidal behaviour has not yet been analysed from a network approach in adolescent samples. It is imperative to incorporate new psychological models to understand suicidal behaviour from a different perspective. The main objective of this work was twofold: (a) to examine suicidal behaviour through network analysis and (b) to estimate the psychological network between suicidal behaviour and protective and risk factors in school-age adolescents.</p></div><div><h3>Method</h3><p>Participants were 443 students (M<!--> <!-->=<!--> <!-->14.3 years; SD<!--> <!-->=<!--> <!-->0.53; 51.2% female) selected incidentally from different schools. Different instruments were administered to assess suicidal behaviour, emotional and behavioural difficulties, prosocial behaviour, subjective well-being, emotional intelligence, self-esteem, depressive symptomatology, empathy, positive and negative affect, and emotional regulation.</p></div><div><h3>Results</h3><p>The resulting network of suicidal behaviour was strongly interconnected. The most central node in terms of strength and expected influence was “Consider taking your own life”. In the estimated psychological network of suicidal behaviour and risk and protective factors, the nodes with the highest strength were depressive symptomatology, positive affect, and empathic concern. The most influential nodes were those related to emotional intelligence abilities. Suicidal behaviour was positively connected to depression symptoms and negative affect, and negatively connected to self-esteem and positive affect. The results of the stability analysis indicated that the networks were accurately estimated.</p></div><div><h3>Conclusions</h3><p>Suicidal behaviour can be conceptualized as a dynamic, complex system of cognitive, emotional, and affective characteristics. The new psychopathological and psychometric models allow us to analyse and understand human behaviour and mental health problems from a new perspective, suggesting new forms of conceptualization, evaluation, intervention, and prevention.</p></div>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":"17 1","pages":"Pages 3-10"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S188898912030032X/pdfft?md5=6132b6050388bd3a6f000ec0b5b8ff21&pid=1-s2.0-S188898912030032X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38006397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fernando Navarro-Mateu , Diego Salmerón , Gemma Vilagut , Mathilde Husky , Mónica Ballesta , María Dolores Chirlaque , José María Huerta , Salvador Martínez , Carmen Navarro , Jordi Alonso , Matthew Nock , Ronald C. Kessler
{"title":"Childhood adversities and suicidal behavior in the general population. The cross-sectional PEGASUS-Murcia Project","authors":"Fernando Navarro-Mateu , Diego Salmerón , Gemma Vilagut , Mathilde Husky , Mónica Ballesta , María Dolores Chirlaque , José María Huerta , Salvador Martínez , Carmen Navarro , Jordi Alonso , Matthew Nock , Ronald C. Kessler","doi":"10.1016/j.rpsm.2020.10.002","DOIUrl":"10.1016/j.rpsm.2020.10.002","url":null,"abstract":"<div><h3>Introduction</h3><p>The aim of the present study is to estimate the lifetime prevalence of suicidal ideation, plans, and attempts in a regional representative sample and the association of these outcomes with sociodemographic factors, prior mental disorders, and childhood adversities.</p></div><div><h3>Material and methods</h3><p>The PEGASUS-Murcia project is a cross-sectional survey of a representative sample of adults in Murcia that is part of the WHO World Mental Health Survey Initiative. The Composite International Diagnostic Interview (CIDI 3.0) was administered face-to-face to 2621 participants (67.4% response rate). The main outcomes were suicidal ideation, plans, and attempts. Lifetime prevalence, age of onset, and risk factors (sociodemographic variables, mental disorders, and childhood adversities) were examined using multiple discrete-time survival models.</p></div><div><h3>Results</h3><p>Lifetime prevalence of suicidal ideation, plans and attempts were 8.0% (standard error, SE: 1.1), 2.1% (SE: 0.3), and 1.2% (SE: 1.1), respectively. Prevalence of any childhood adversities was 22.1% (SE: 1.3) in the total sample and, even higher, among those with suicide related outcomes (ranging between 36.8% and 53.7%). Female sex, younger age, prior (to onset of the outcome) lifetime prevalence of mood disorders, number of mental disorders, and exposure to childhood adversity were associated with significantly increased odds of suicidal ideation and plans.</p></div><div><h3>Conclusions</h3><p>Lifetime prevalence estimates of suicidality are similar to those in community epidemiological surveys. Childhood adversities and mental disorders, especially mood disorders, are important risk factors for suicidality. Early detection of these adversities and disorders should be targeted in suicide prevention programs.</p></div>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":"17 1","pages":"Pages 11-18"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1888989120301166/pdfft?md5=be24000cf0fc0ccde417aabd96e94416&pid=1-s2.0-S1888989120301166-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38524616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luciana Miguel-Alhambra , María Goretti Morón-Nozaleda , Raquel Chacón-Campollo , Silvia Yañez-López , Mar Faya Barrios , Monserrat Graell Berna
{"title":"Legal requirements for admission of children and adolescent patients to in-home mental health services: The case of the Niño Jesús Hospital at home unit in Madrid, Spain","authors":"Luciana Miguel-Alhambra , María Goretti Morón-Nozaleda , Raquel Chacón-Campollo , Silvia Yañez-López , Mar Faya Barrios , Monserrat Graell Berna","doi":"10.1016/j.sjpmh.2023.03.001","DOIUrl":"10.1016/j.sjpmh.2023.03.001","url":null,"abstract":"","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":"17 1","pages":"Pages 55-56"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2950285323000066/pdfft?md5=b731c476e69615941724fa6f6832e173&pid=1-s2.0-S2950285323000066-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90904005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clara De Castro , Mireia Solerdelcoll , Maria Teresa Plana , Irene Halperin , Mireia Mora , Laura Ribera , Camil Castelo-Branco , Esther Gómez-Gil , Angela Vidal
{"title":"High persistence in Spanish transgender minors: 18 years of experience of the Gender Identity Unit of Catalonia","authors":"Clara De Castro , Mireia Solerdelcoll , Maria Teresa Plana , Irene Halperin , Mireia Mora , Laura Ribera , Camil Castelo-Branco , Esther Gómez-Gil , Angela Vidal","doi":"10.1016/j.rpsm.2022.02.001","DOIUrl":"10.1016/j.rpsm.2022.02.001","url":null,"abstract":"<div><h3>Introduction</h3><p>An increasing number of transgender minors are seeking help during the development of their gender identity and transitioning. Understanding their characteristics and the impact of transitioning on their mental health would be of help in the development of protocols to offer a better assistance to this population. The aim of this study was to examine the socio-demographic characteristics and clinical data related to gender identity, transitioning and persistence of transgender minors who were seen at the Gender Identity Unit (GID) of Catalonia, Spain.</p></div><div><h3>Material and methods</h3><p>All underage applicants who requested clinical assistance at the specialized GID from 1999 until 2016 were retrospectively evaluated using the minors’ medical records.</p></div><div><h3>Results</h3><p>124 out of 140 minors were confirmed as being transgender, 83.1% of them were adolescents. The assigned male/female ratio was 1:1.2. 97.6% persisted in their transgender identity after a median follow-up time of 2.6 years. Prior to the first meeting, 48.5% were living in their affirmed role and, by the end of the study, this percentage rose to 87.1%. Yearly, the number of referrals exponentially grew whereas the age at referral decreased (<em>rs</em> <!-->=<!--> <!-->−0.2689, <em>p</em> <!-->=<!--> <!-->0.0013). Child consultations rose to a significant percentage (23.5%) over the last 6 years.</p></div><div><h3>Conclusions</h3><p>Over the 18-year period, the number of referrals increased considerably, more assigned natal female minors and children were seen, and more minors made the decision to go through social transition at a younger age. In contrast with other epidemiological studies conducted in this field, a consistently high rate of persistence was observed.</p></div>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":"17 1","pages":"Pages 35-40"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1888989122000283/pdfft?md5=5b57157b29a40d337d9f47b6c9e486a4&pid=1-s2.0-S1888989122000283-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83164414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Julia Buesa , Laura Campos-Berga , Marta Lizaran , Belén Almansa , Farah Ghosn , Pilar Sierra , Julia Andreu , Máximo Vento , Vicente Diago , Ana García-Blanco
{"title":"Predictors of postpartum depression in threatened preterm labour: Importance of psychosocial factors","authors":"Julia Buesa , Laura Campos-Berga , Marta Lizaran , Belén Almansa , Farah Ghosn , Pilar Sierra , Julia Andreu , Máximo Vento , Vicente Diago , Ana García-Blanco","doi":"10.1016/j.sjpmh.2023.06.004","DOIUrl":"10.1016/j.sjpmh.2023.06.004","url":null,"abstract":"<div><h3>Background</h3><p>Postpartum depression (PPD) is more common in high-risk pregnancies. One of the main causes of high-risk pregnancy is threatened preterm labour (TPL), a stressful event which involves psychological consequences for the mother. The objective of this study was to identify those psychosocial factors that may imply a greater risk of PPD in TPL women.</p></div><div><h3>Material and methods</h3><p>A prospective cohort study was carried out, consisting of a sample of 149 pregnant women who suffered from a TPL during pregnancy, and 61 controls. At the time of inclusion, demographic, obstetric, biological, and psychosocial variables were collected. At 3 months postpartum, depressive symptoms were evaluated along with their predictive factors.</p></div><div><h3>Results</h3><p>Women who suffered TPL showed higher scores in depressive symptomatology (<em>F</em> (1, 208)<!--> <!-->=<!--> <!-->7.46, <em>p</em> <!-->=<!--> <!-->.007), as well as higher probability of PPD diagnosis than controls (<em>χ</em><sup>2</sup> (1)<!--> <!-->=<!--> <!-->8.05, <em>p</em> <!-->=<!--> <!-->005). Higher maternal age (+.335), lower educational level (−2.15), history of trauma (+.28) and higher trait anxiety scores (+.314) were the main predictors of PPD after TPL.</p></div><div><h3>Conclusions</h3><p>Experiencing TPL during pregnancy, carries a higher risk of PPD. This risk is mediated by sociodemographic and psychological factors related to chronic stress. The detection of these potentially modifiable risk factors in pregnant women after experiencing TPL would help prevent PPD and improve the maternal–infant prognosis.</p></div>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":"17 1","pages":"Pages 51-54"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2950285323000339/pdfft?md5=9ffc9b4b4aacb41ddc768f0a1416f43f&pid=1-s2.0-S2950285323000339-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135588297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pablo Navalón , Jéssica Merchan-Naranjo , Farah Ghosn , Belén Almansa , Consuelo Chafer-Pericas , Javier González-Peñas , Elisa Rodríguez-Toscano , Susana Zeballos , María Arriaga , Pedro Castro Castro , Dorotea Blanco Bravo , Máximo Vento , Laura Pina-Camacho , Ana García-Blanco
{"title":"Study of the pathophysiological mechanisms associated with the onset and course of neurodevelopmental disorders in preterm infants (the PeriSTRESS-PremTEA study): Rationale, objectives, design and sample description","authors":"Pablo Navalón , Jéssica Merchan-Naranjo , Farah Ghosn , Belén Almansa , Consuelo Chafer-Pericas , Javier González-Peñas , Elisa Rodríguez-Toscano , Susana Zeballos , María Arriaga , Pedro Castro Castro , Dorotea Blanco Bravo , Máximo Vento , Laura Pina-Camacho , Ana García-Blanco","doi":"10.1016/j.rpsm.2021.02.002","DOIUrl":"10.1016/j.rpsm.2021.02.002","url":null,"abstract":"<div><h3>Background</h3><p>There are few studies exploring the pathophysiological pathways that may condition differentially the emergence/course of neurodevelopmental disorders (ND) in very preterm and extremely preterm newborns (VPTN/EPTN). Furthermore, there are no established biological markers predictive of ND in this population. The aim of this study is four-fold: in two cohorts of VPTN/EPTN (i) to characterize the emergence/course of ND up to corrected-age 6 years, (ii) to identify those factors (from prenatal stages up to age 6 years) that explain the interindividual differences related to emergence/course of ND, (iii) to identify in the first hours/days of life a urinary metabolomic biomarker profile predictive of ND, and (iv) to determine longitudinally variations in DNA methylation patterns predictive of ND.</p></div><div><h3>Methods</h3><p>Observational, longitudinal, prospective, six-year follow-up, multicentre collaborative study. Two cohorts are being recruited: the PeriSTRESS-Valencia-cohort (<em>n</em> <!-->=<!--> <!-->26 VPTN, 18 EPTN, and 122 born-at-term controls), and the PremTEA-Madrid-cohort (<em>n</em> <!-->=<!--> <!-->49 EPTN and <em>n</em> <!-->=<!--> <!-->29 controls).</p></div><div><h3>Results</h3><p>We describe the rationale, objectives and design of the PeriSTRESS-PremTEA project and show a description at birth of the recruited samples.</p></div><div><h3>Conclusions</h3><p>The PeriSTRESS-PremTEA project could help improve early identification of clinical, environmental and biological variables involved in the physiopathology of ND in VPTN/EPTN. It could also help to improve the early identification of non-invasive ND biomarkers in this population. This may allow early ND detection as well as early and personalised intervention for these children.</p></div>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":"17 1","pages":"Pages 19-27"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1888989121000288/pdfft?md5=141d44430ae250cf504ff85f71f2f768&pid=1-s2.0-S1888989121000288-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25394313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aldo Pereira , Vanesa Richarte , Christian Fadeuilhe , Montse Corrales , Estela García , Josep Antoni Ramos-Quiroga
{"title":"ADHD Rating Scale (ADHD-RS): Validation in Spanish in adult population according to the DSM-5","authors":"Aldo Pereira , Vanesa Richarte , Christian Fadeuilhe , Montse Corrales , Estela García , Josep Antoni Ramos-Quiroga","doi":"10.1016/j.sjpmh.2023.06.002","DOIUrl":"10.1016/j.sjpmh.2023.06.002","url":null,"abstract":"<div><h3>Introduction</h3><p>Attention deficit hyperactivity disorder (ADHD) is the most common childhood neurodevelopmental disorder, with an estimated prevalence in adulthood of 2.5–3.4%. The Attention Deficit/Hyperactivity Disorder Rating Scale (ADHD-RS) is an 18-item self-administered scale that assesses attention deficit and hyperactivity/impulsivity symptoms of ADHD in adults. This study aims to validate the ADHD-RS in Spanish according to the diagnostic criteria established by the 5th edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5).</p></div><div><h3>Materials and methods</h3><p>A sample of 441 adult patients (mean age 33.34<!--> <!-->±<!--> <!-->11.37 years) was included, 396 subjects were diagnosed with ADHD (mean age 33.17<!--> <!-->±<!--> <!-->11.18 years), and 45 were controls (mean age 35.40<!--> <!-->±<!--> <!-->12.33 years). The clinical diagnosis of ADHD was established according to the DSM-5 criteria. The ADHD-RS was subsequently administered to all participants.</p><p>A logistic regression study evaluated the model in terms of sensitivity, specificity, positive predictive value, and negative predictive value. The Kaiser-Meyer-Olkin (KMO) measure was performed to assess the adequacy of the data set, and to determine whether factor analysis was applicable, Bartlett's sphericity test was performed.</p><p>Principal component analysis was used, using the Varimax orthogonal rotation method, which minimizes the number of variables with high loads on each factor, obtaining two factors and thus, simplifying their interpretation.</p></div><div><h3>Results</h3><p>The cut-off point that best discriminates the combined presentation of ADHD was 24 points, with a sensitivity of 94.78%, a specificity of 84.79%, a PPV (positive predictive value) of 93.74%, and an NPV (negative predictive value) of 78.33, with an area under the curve (AUC) of 0.85, and a kappa coefficient of 0.86.</p><p>Regarding inattentive ADHD, the cut-off point that best discriminates was 21 points, with a sensitivity of 92.56%, a specificity of 76.26%, a PPV of 92.01%, an NPV of 78.33%, an AUC of 0.90, and a kappa coefficient of 0.87.</p><p>Different cut-off values in the two subgroups suggests that a differentiated cut-off point for the inattentive and combined presentations may be an adequate assessment strategy for ADHD in adulthood.</p></div><div><h3>Conclusions</h3><p>The Spanish version of the ADHD-RS is a valid instrument to evaluate ADHD in adults according to the diagnostic criteria established by the DSM-5.</p><p>Differentiated cut-off points for the inattentive and combined presentations discriminate more accurately than a single cut-off point.</p></div>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":"17 1","pages":"Pages 46-50"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2950285323000145/pdfft?md5=aa4f589b5a4eac98d0edcc5fcce930a2&pid=1-s2.0-S2950285323000145-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134995340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}