Spanish Journal of Psychiatry and Mental Health最新文献

{"title":"Latin American consensus recommendations for the management and treatment of patients with treatment-resistant depression (TRD)","authors":"Ricardo Corral ,&nbsp;Enrique Bojórquez ,&nbsp;Marcelo Cetkovich-Bakmas ,&nbsp;Rodrigo Córdoba ,&nbsp;Julio Chestaro ,&nbsp;Clarissa Gama ,&nbsp;Gerardo García Bonetto ,&nbsp;Carlos López Jaramillo ,&nbsp;Ricardo Alberto Moreno ,&nbsp;Bernardo Ng ,&nbsp;Edilberto Pena de Leon ,&nbsp;Luis Risco ,&nbsp;Hernán Silva ,&nbsp;Gustavo Vazquez","doi":"10.1016/j.sjpmh.2023.06.001","DOIUrl":"10.1016/j.sjpmh.2023.06.001","url":null,"abstract":"<div><div>Despite the abundance of literature on treatment-resistant depression (TRD), there is no universally accepted definition of TRD, and available treatment pathways for the management of TRD vary across the Latin American region, highlighting the need for a uniform definition and treatment principles to optimize the management of TRD in Latin America.</div></div><div><h3>Methods</h3><div>Following a thematic literature review and pre-meeting survey, a Latin America expert panel comprising 14 psychiatrists with clinical experience in managing patients with TRD convened and utilized the RAND/UCLA appropriateness method to develop consensus-based recommendations on the appropriate definition of TRD and principles for its management.</div></div><div><h3>Results</h3><div><span>The expert panel agreed that ‘treatment-resistant depression’ (TRD) is defined as ‘failure of two drug treatments of adequate doses, for 4–8 weeks duration with adequate adherence, during a major depressive episode’. A stepwise treatment approach should be employed for the management of TRD – treatment strategies can include maximizing dose, switching to a different class, and augmenting or combining treatments. Nonpharmacological treatments, such as </span>electroconvulsive therapy, are also appropriate options for patients with TRD.</div></div><div><h3>Conclusion</h3><div>These consensus recommendations on the operational definition of TRD and approved treatments for its management can be adapted to local contexts in the Latin American countries but should not replace clinical judgement. Individual circumstances and benefit–risk balance should be carefully considered while determining the most appropriate treatment option for patients with TRD.</div></div>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":"18 3","pages":"Pages 208-215"},"PeriodicalIF":2.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135429468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High levels of TNF-α are associated with symptoms of depression in health professionals at a hospital","authors":"Pablo L. Martino ,&nbsp;Matias M. Pulopulos ,&nbsp;Celia Del Canto ,&nbsp;María L. Dupanlou ,&nbsp;Stella M. Rubio ,&nbsp;José L. Bonet","doi":"10.1016/j.rpsm.2021.10.002","DOIUrl":"10.1016/j.rpsm.2021.10.002","url":null,"abstract":"<div><h3>Objective</h3><div>The current evidence indicates that inflammation is highly related to depression but not to anxiety in clinical samples. However, less understood is the relationship between inflammation and symptoms of depression and anxiety in a nonclinical sample. The aim of this study was to investigate the association between three inflammation markers and symptoms of depression and anxiety in a healthy sample without a history of psychiatric disorders.</div></div><div><h3>Methods</h3><div>Symptoms of depression and anxiety were evaluated in 74 healthy adults (mean age<!--> <!-->=<!--> <!-->42.3; SD<!--> <!-->=<!--> <span>11.8) using the Hospital Anxiety and Depression Scale<span><span>. We assessed proinflammatory cytokines (TNF-α, IL-1β, and CRP), and morning </span>cortisol levels using blood samples.</span></span></div></div><div><h3>Results</h3><div>TNF-α correlates positively with depressive symptoms, but there were no significant relationships between anxiety scores and inflammation markers. Importantly, TNF-α relates to symptoms of depression independently of anxiety scores, age, body mass index<span>, cortisol, and sex.</span></div></div><div><h3>Conclusions</h3><div>Our results indicate that TNF-α is associated with depressive symptoms, independently of anxiety, age, body mass index<span>, cortisol, and sex, even in a sample of hospital health professionals without diagnosis or psychiatric history.</span></div></div>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":"18 3","pages":"Pages 169-173"},"PeriodicalIF":2.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74959091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations between unhealthy lifestyle and depression: Cross-sectional results from the Spanish National Health Survey","authors":"Guillem Navarra-Ventura ,&nbsp;Victoria Coronado-Simsic ,&nbsp;Pau Riera-Serra ,&nbsp;Adoración Castro ,&nbsp;Mauro García-Toro ,&nbsp;Miquel Roca ,&nbsp;Margalida Gili","doi":"10.1016/j.sjpmh.2023.08.001","DOIUrl":"10.1016/j.sjpmh.2023.08.001","url":null,"abstract":"<div><h3>Introduction</h3><div>Depression usually worsens lifestyle habits, but previous evidence also suggests that an unhealthy lifestyle (UL) increases the risk of depression. Many studies have analyzed the association between lifestyle and depression in several nationally representative samples, but none have done so in the Spanish adult population. Our aim was to examine the associations between UL habits and depression in Spain.</div></div><div><h3>Materials and methods</h3><div>Analysis of cross-sectional data from the latest National Health Survey published in 2018 (<em>N</em> <!-->=<!--> <!-->23,089). Data on depression and 4 lifestyle factors (diet, physical exercise, smoking, and alcohol consumption) were used. These factors were combined into an UL index ranging from 0 (healthiest lifestyle) to 4 (unhealthiest lifestyle). The prevalence of depression at different levels of the UL index, and the association between depression and both the cumulative UL index and the 4 UL factors was analyzed using parametric and non-parametric tests.</div></div><div><h3>Results</h3><div>Sedentarism was the most prevalent UL factor, followed by unhealthy diet, smoking and high-risk alcohol consumption. Having ≥1 UL factors was associated with a higher prevalence of depression compared to having 0 UL factors (2.5% vs. ≥5.2%), regardless of the cumulative number UL factors (1, 2, 3 or 4). Being physically inactive (OR<!--> <!-->=<!--> <!-->1.6) and a smoker (OR<!--> <!-->=<!--> <!-->1.3) increased the likelihood of depression. Being a high-risk wine drinker (OR<!--> <!-->=<!--> <!-->0.26) decreased the likelihood of depression. Dietary intake was not significant.</div></div><div><h3>Conclusions</h3><div>The prevalence of depression changes depending on several modifiable lifestyle factors. Policy makers should therefore spare no resources in promoting strategies to encourage healthy lifestyles and prevent the acquisition of UL habits.</div></div>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":"18 3","pages":"Pages 191-198"},"PeriodicalIF":2.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134937291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A psychiatrist in the court of Philip II of Spain: Mental medicine in the work of Francisco Valles (1524–1592)","authors":"David Fraguas","doi":"10.1016/j.sjpmh.2024.08.001","DOIUrl":"10.1016/j.sjpmh.2024.08.001","url":null,"abstract":"","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":"18 3","pages":"Pages 155-157"},"PeriodicalIF":2.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142074922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Depression and suicide: Untangling the web from epidemiology to mechanisms","authors":"Benedicto Crespo-Facorro ,&nbsp;Gin S. Malhi","doi":"10.1016/j.sjpmh.2025.09.001","DOIUrl":"10.1016/j.sjpmh.2025.09.001","url":null,"abstract":"","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":"18 3","pages":"Pages 153-154"},"PeriodicalIF":2.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145190140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mortalidad por suicidio en España (1984-2018): análisis edad-período-cohorte","authors":"Lucia Cayuela ,&nbsp;Agustín Sánchez Gayango ,&nbsp;Paula Antona Sánchez-Trincado ,&nbsp;Susana Rodríguez-Domínguez ,&nbsp;Antonio Andrés Velasco Quiles ,&nbsp;Aurelio Cayuela","doi":"10.1016/j.rpsm.2020.05.010","DOIUrl":"10.1016/j.rpsm.2020.05.010","url":null,"abstract":"<div><h3>Objetivo</h3><div>Evaluar los efectos de la edad, período y cohorte sobre la tendencia de la mortalidad por suicidio en España (1984-2018).</div></div><div><h3>Métodos</h3><div>Los datos de mortalidad y población se obtuvieron del Instituto Nacional de Estadísticas. El análisis del efecto de la edad, el período de muerte y la cohorte de nacimiento sobre la evolución de la mortalidad por suicidio en el período 1984-2018 se realizó utilizando una herramienta web para el análisis edad-período-cohorte proporcionada por la División de Epidemiología y Genética del Cáncer del Instituto Nacional del Cáncer de EE. UU.</div></div><div><h3>Resultados</h3><div>Las tasas aumentan en función de la edad (efecto edad) en ambos sexos. El efecto período muestra, en los hombres, un aumento durante el período 1984-1998 seguido de un descenso significativo hasta 2018. En las mujeres, las tasas permanecen estables durante el período 1987-2002, descienden durante 2007-2012 (p &lt; 0,05) y se estabilizan al final. Tanto en hombres como en mujeres el riesgo disminuyó en cada cohorte de nacimiento sucesiva nacida entre 1904 y 1939. Posteriormente, los riesgos aumentaron hasta la cohorte de nacidos durante el período 1964-1974 a partir de los que el riesgo disminuye en los hombres y permanece estable en las mujeres.</div></div><div><h3>Conclusión</h3><div>Una mejor comprensión de los efectos de la cohorte de nacimiento podría abrir nuevas puertas a la prevención del suicidio.</div></div>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":"18 3","pages":"Pages 163-168"},"PeriodicalIF":2.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38163481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antidepressants overuse in primary care: Prescription trends between 2010 and 2019 in Catalonia","authors":"Gerard Anmella ,&nbsp;Miriam Sanabra ,&nbsp;Mireia Primé-Tous ,&nbsp;Xavier Segú ,&nbsp;Aleix Solanes ,&nbsp;Victoria Ruíz ,&nbsp;Ivette Morilla ,&nbsp;Antonieta Also Fontanet ,&nbsp;Elisenda Sant ,&nbsp;Sandra Murgui ,&nbsp;Mireia Sans-Corrales ,&nbsp;Anabel Martínez-Aran ,&nbsp;Giovanna Fico ,&nbsp;Michele De Prisco ,&nbsp;Vincenzo Oliva ,&nbsp;Andrea Murru ,&nbsp;Roland Zahn ,&nbsp;Allan H. Young ,&nbsp;Victor Vicens ,&nbsp;Clara Viñas-Bardolet ,&nbsp;Diego Hidalgo-Mazzei","doi":"10.1016/j.rpsm.2022.12.001","DOIUrl":"10.1016/j.rpsm.2022.12.001","url":null,"abstract":"<div><h3>Introduction</h3><div>There has been an increase in the prescription of antidepressants (AD) in primary care (PC). However, it is unclear whether this was explained by a rise in diagnoses with an indication for AD. We investigated the changes in frequency and the variables associated with AD prescription in Catalonia, Spain.</div></div><div><h3>Methods</h3><div><span>We retrieved AD prescription, sociodemographic, and health-related data using individual electronic health records from a population-representative sample (</span><em>N</em> <!-->=<!--> <!-->947.698) attending PC between 2010 and 2019. Prescription of AD was calculated using DHD (Defined Daily Doses per 1000 inhabitants/day). We compared cumulative changes in DHD with cumulative changes in diagnoses with an indication for AD during the study period. We used Poisson regression to examine sociodemographic and health-related variables associated with AD prescription.</div></div><div><h3>Results</h3><div>Both AD prescription and mental health diagnoses with an indication for AD gradually increased. At the end of the study period, DHD of AD prescriptions and mental health diagnoses with an indication for AD reached cumulative increases of 404% and 49% respectively. Female sex (incidence rate ratio (IRR)<!--> <!-->=<!--> <!-->2.83), older age (IRR<!--> <!-->=<!--> <!-->25.43), and lower socio-economic status (IRR<!--> <!-->=<!--> <!-->1.35) were significantly associated with increased risk of being prescribed an AD.</div></div><div><h3>Conclusions</h3><div>Our results from a large and representative cohort of patients confirm a steady increase of AD prescriptions that is not explained by a parallel increase in mental health diagnoses with an indication for AD. A trend on AD off-label and over-prescriptions in the PC system in Catalonia can be inferred from this dissociation.</div></div>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":"18 3","pages":"Pages 174-181"},"PeriodicalIF":2.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41133176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effective connectivity of the locus coeruleus in patients with late-life Major Depressive Disorder or mild cognitive impairment","authors":"Pablo Maturana-Quijada ,&nbsp;Pamela Chavarría-Elizondo ,&nbsp;Inés del Cerro ,&nbsp;Ignacio Martínez-Zalacaín ,&nbsp;Asier Juaneda-Seguí ,&nbsp;Andrés Guinea-Izquierdo ,&nbsp;Jordi Gascón-Bayarri ,&nbsp;Ramón Reñé ,&nbsp;Mikel Urretavizcaya ,&nbsp;José M. Menchón ,&nbsp;Isidre Ferrer ,&nbsp;Virginia Soria ,&nbsp;Carles Soriano-Mas","doi":"10.1016/j.sjpmh.2024.02.002","DOIUrl":"10.1016/j.sjpmh.2024.02.002","url":null,"abstract":"<div><h3>Introduction</h3><div>We compared effective connectivity from the locus coeruleus (LC) during the resting-state in patients with late-life Major Depressive Disorder (MDD), individuals with amnestic Mild Cognitive Impairment (aMCI), and Healthy Controls (HCs).</div></div><div><h3>Participants</h3><div>23 patients with late-life MDD, 22 patients with aMCI, and 28 HCs.</div></div><div><h3>Material and methods</h3><div>Participants were assessed in two time-points, 2 years apart. They underwent a resting-state functional magnetic resonance imaging and a high-resolution anatomical acquisition, as well as clinical assessments. Functional imaging data were analyzed with dynamic causal modeling, and parametric empirical Bayes model was used to map effective connectivity between 7 distinct nodes: 4 from the locus coeruleus and 3 regions displaying gray matter decreases during the two-year follow-up period.</div></div><div><h3>Results</h3><div>Longitudinal analysis of structural data identified three clusters of larger over-time gray matter volume reduction in patients (MDD<!--> <!-->+<!--> <!-->aMCI vs. HCs): the right precuneus, and the visual association and parahippocampal cortices. aMCI patients showed decreased effective connectivity from the left rostral to caudal portions of the LC, while connectivity from the left rostral LC to the parahippocampal cortex increased. In MDD, there was a decline in effective connectivity across LC caudal seeds, and increased connectivity from the left rostral to the left caudal LC seed over time. Connectivity alterations with cortical regions involved cross-hemisphere increases and same-hemisphere decreases.</div></div><div><h3>Conclusions</h3><div>Our discoveries provide insight into the dynamic changes in effective connectivity in individuals with late-life MDD and aMCI, also shedding light on the mechanisms potentially contributing to the onset of neurodegenerative disorders.</div></div>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":"18 3","pages":"Pages 199-207"},"PeriodicalIF":2.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140061691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical predictors and psychosocial risk factors of suicide attempt severity","authors":"Itxaso González-Ortega ,&nbsp;Marina Diaz-Marsa ,&nbsp;Purificación López-Peña ,&nbsp;Jessica Fernández-Sevillano ,&nbsp;Jorge Andreo-Jover ,&nbsp;Julio Bobes ,&nbsp;María Fe Bravo-Ortiz ,&nbsp;Ana Isabel Cebria ,&nbsp;Benedicto Crespo-Facorro ,&nbsp;Alejandro de la Torre-Luque ,&nbsp;Matilde Elices ,&nbsp;Verónica Fernández-Rodrigues ,&nbsp;Nathalia Garrido-Torres ,&nbsp;Iria Grande ,&nbsp;Ángela Palao-Tarrero ,&nbsp;Andrés Pemau ,&nbsp;Natalia Roberto ,&nbsp;Miguel Ruiz-Veguilla ,&nbsp;Elisa Seijo-Zazo ,&nbsp;Susana Alberich ,&nbsp;Iñaki Zorrilla","doi":"10.1016/j.sjpmh.2023.07.002","DOIUrl":"10.1016/j.sjpmh.2023.07.002","url":null,"abstract":"<div><h3>Background</h3><div>Suicide attempts are an important predictor of completed suicide and may differ in terms of severity of medical consequences or medical lethality. There is little evidence on serious suicide attempt (SSA) and very few studies have compared SSA with non-SSA.</div></div><div><h3>Objective</h3><div>The aim of this multisite, coordinated, cohort study was to analyze the role of clinical variables and the sociodemographic and psychological risk factors of SSA.</div></div><div><h3>Method</h3><div>In this multisite, coordinated, cohort study, 684 participants (222 for the mild suicide attempt group, 371 for the moderate suicide attempt group and 91 for the SSA group) were included in the study. Ordinal regression models were performed to analyze the predictor variables of SSA.</div></div><div><h3>Results</h3><div>Early physical abuse (OR<!--> <!-->=<!--> <!-->1.231) and impulsivity (OR<!--> <!-->=<!--> <!-->1.036) were predictors of SSA, while depressive symptoms were associated with a lower risk of SSA.</div></div><div><h3>Conclusion</h3><div>Environmental and psychological factors as physical abuse and impulsivity are related with severe suicide severity. These findings will help to develop strategies to prevent suicide and may be considered for the treatment and management of suicide.</div></div>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":"18 3","pages":"Pages 182-190"},"PeriodicalIF":2.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135588290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Upward trends in eating disorders, self-harm, and suicide attempt emergency admissions in female adolescents after COVID-19 lockdown","authors":"Adriana Fortea ,&nbsp;Lydia Fortea ,&nbsp;Marta Gómez-Ramiro ,&nbsp;Giovanna Fico ,&nbsp;Anna Giménez-Palomo ,&nbsp;Maria Sagué-Vilavella ,&nbsp;Maria Teresa Pons ,&nbsp;Mireia Vázquez ,&nbsp;Nuria Baldaquí ,&nbsp;Lluc Colomer ,&nbsp;Tábatha Maria Fernández ,&nbsp;Felipe Gutiérrez-Arango ,&nbsp;Maria Llobet ,&nbsp;Ester Pujal ,&nbsp;Luisa Lázaro ,&nbsp;Eduard Vieta ,&nbsp;Joaquim Radua ,&nbsp;Inmaculada Baeza","doi":"10.1016/j.sjpmh.2023.09.003","DOIUrl":"10.1016/j.sjpmh.2023.09.003","url":null,"abstract":"<div><h3>Introduction</h3><div>Increased mental health problems have been reported in children and adolescents related to the COVID-19 lockdown and its immediate aftermath, especially among adolescent females. However, the longer-term impact of persistent quarantine measures and social restrictions on this population is yet to be further explored.</div></div><div><h3>Materials and methods</h3><div>We compared the number of children/adolescents admissions to the psychiatric emergency<span> department (ED) of Hospital Clínic de Barcelona during the COVID-19 lockdown and the following year with the numbers of admissions the year before lockdown, adjusting for variations in the population. We also conducted separate analyses by gender, age group, and diagnostic categories. Finally, we also repeated the analyses considering the cumulated deficit/excess since the start of the lockdown. Statistical significance was estimated using binomial tests with Bonferroni correction.</span></div></div><div><h3>Results</h3><div>A total of 2425 admissions were recorded. Globally, admission rates decreased during the lockdown (46%) and progressively increased during the one-year aftermath (43% by spring 2021). This increase was particularly high in adolescent females (85%) while unclear in children and/or males. The main diagnostic categories involved were anxiety, depressive, and eating disorders, as well as self-harm behavior, suicidal ideation, and suicide attempts. The increase in eating disorders, self-harm behavior, and suicide attempts admissions in female adolescents remained statistically significant when considering the cumulated deficit/excess.</div></div><div><h3>Conclusions</h3><div>We found increased ED admissions during the aftermath of the COVID-19 lockdown among adolescent females. We recommend strengthening the attention to this population to provide adequate specialized care and prevention strategies.</div></div>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":"18 3","pages":"Pages 158-162"},"PeriodicalIF":2.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134978155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}