Spanish Journal of Psychiatry and Mental Health最新文献

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Platelet and white blood-cell-based ratios: Differential inflammatory markers of severe mental disorders? 血小板和白细胞比率:严重精神障碍的炎性标志物?
IF 2.8
Spanish Journal of Psychiatry and Mental Health Pub Date : 2025-10-01 Epub Date: 2023-09-12 DOI: 10.1016/j.sjpmh.2023.03.002
Gonzalo Paniagua , Leticia González-Blanco , Pilar A. Sáiz , Carlota Moya-Lacasa , Laura Gutiérrez , Patricia Martínez-Botía , Francesco Dal Santo , Luis Jiménez-Treviño , María Paz García-Portilla , Julio Bobes
{"title":"Platelet and white blood-cell-based ratios: Differential inflammatory markers of severe mental disorders?","authors":"Gonzalo Paniagua ,&nbsp;Leticia González-Blanco ,&nbsp;Pilar A. Sáiz ,&nbsp;Carlota Moya-Lacasa ,&nbsp;Laura Gutiérrez ,&nbsp;Patricia Martínez-Botía ,&nbsp;Francesco Dal Santo ,&nbsp;Luis Jiménez-Treviño ,&nbsp;María Paz García-Portilla ,&nbsp;Julio Bobes","doi":"10.1016/j.sjpmh.2023.03.002","DOIUrl":"10.1016/j.sjpmh.2023.03.002","url":null,"abstract":"<div><h3>Introduction</h3><div>Neutrophil/lymphocyte (NLR), monocyte/lymphocyte (MLR), and platelet/lymphocyte (PLR) ratios, and systemic inflammatory index (SII) represent peripheral markers of inflammation associated with different severe mental disorders.</div></div><div><h3>Material and methods</h3><div>In this study, these parameters were analyzed in a sample of 622 participants [197 patients with major depressive disorder (MDD), 154 with bipolar disorder (BD), 176 with schizophrenia (SCH), and 95 healthy controls (HC)]. Sociodemographic and clinical data of patients were recorded.</div></div><div><h3>Results</h3><div>Differences in age and sex were detected among groups (<em>p</em> <!-->&lt;<!--> <!-->0.001), with SCH patients being younger and MDD patients being older. After stratifying by sex, these ratios were compared using the nonparametric ANCOVA (Quade's test) using age as a covariate. In males, no significant statistical differences were found between groups. However, differences were observed in MLR in the subgroup of females [MDD: 0.23 (SD<!--> <!-->=<!--> <!-->0.09); BD: 0.23 (SD<!--> <!-->=<!--> <!-->0.11); SCH: 0.24 (SD<!--> <!-->=<!--> <!-->0.11); HC: 0.29 (SD<!--> <!-->=<!--> <!-->0.13); <em>F</em> <!-->=<!--> <!-->5.376, <em>p</em> <!-->=<!--> <!-->0.001]. Post hoc testing revealed that there are MLR differences between HC versus MDD and between HC versus BD, with higher values in HC versus the other two groups. On the other hand, no differences were found in either males or females for any of the studied ratios, among the three diagnostic groups.</div></div><div><h3>Conclusions</h3><div>MLR is reduced in MDD and BD patients versus HC, but exclusively in the female group. However, based on the analyzed indices, it is not possible to differentiate among the three diagnostic groups of patients. As a limitation of this study, note that the effects of psychopharmacological treatments and smoking have not been controlled for.</div></div>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":"18 4","pages":"Pages 250-255"},"PeriodicalIF":2.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135298482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intestinal permeability and low-grade chronic inflammation in schizophrenia: A multicentre study on biomarkers. Rationale, objectives, protocol and preliminary results 精神分裂症患者肠通透性和低级别慢性炎症:一项多中心生物标志物研究。基本原理、目标、方案和初步结果
IF 2.8
Spanish Journal of Psychiatry and Mental Health Pub Date : 2025-10-01 Epub Date: 2023-10-12 DOI: 10.1016/j.sjpmh.2023.09.005
Gerard Anmella , Silvia Amoretti , Gemma Safont , Ana Meseguer , Eduard Vieta , Maria Teresa Pons-Cabrera , Miqueu Alfonso , Carla Hernández , Monica Sanchez-Autet , Ferran Pérez-Baldellou , Leticia González-Blanco , Maria Paz García-Portilla , Miquel Bernardo , Belén Arranz
{"title":"Intestinal permeability and low-grade chronic inflammation in schizophrenia: A multicentre study on biomarkers. Rationale, objectives, protocol and preliminary results","authors":"Gerard Anmella ,&nbsp;Silvia Amoretti ,&nbsp;Gemma Safont ,&nbsp;Ana Meseguer ,&nbsp;Eduard Vieta ,&nbsp;Maria Teresa Pons-Cabrera ,&nbsp;Miqueu Alfonso ,&nbsp;Carla Hernández ,&nbsp;Monica Sanchez-Autet ,&nbsp;Ferran Pérez-Baldellou ,&nbsp;Leticia González-Blanco ,&nbsp;Maria Paz García-Portilla ,&nbsp;Miquel Bernardo ,&nbsp;Belén Arranz","doi":"10.1016/j.sjpmh.2023.09.005","DOIUrl":"10.1016/j.sjpmh.2023.09.005","url":null,"abstract":"<div><h3>Background</h3><div>Altered intestinal permeability<span><span> and low-grade chronic inflammation disrupt the integrity of the blood–brain barrier (microbiota–gut–brain axis), probably playing a role in the </span>pathophysiology of schizophrenia-spectrum disorders. However, studies assessing the microbiota–gut–brain axis are inconsistent. This article describes the rationale, objectives, protocol, and presents descriptive results for a new project.</span></div></div><div><h3>Methods</h3><div><span>The sample of this study came from an observational, cross-sectional and multisite study including four centers in Spain (PI17/00246) recruiting adult patients with DSM-5 schizophrenia-spectrum disorders at any stage of the disease. The aims of the project are to assess the interrelation between intestinal permeability<span> and low-grade chronic inflammation in schizophrenia-spectrum disorders and the role of peripheral biomarkers, diet, exercise, </span></span>metabolic syndrome<span>, disease severity and functioning as well as cognition. Assessments included the following variables: (1) anthropometric, (2) intestinal permeability, diet, and physical exercise, (3) clinical and functional, (4) neuropsychological and cognitive reserve, and (5) peripheral biomarkers from blood.</span></div></div><div><h3>Results</h3><div>A total of 646 patients were enrolled (257, 39.7% female). Mean age was 43.2<!--> <!-->±<!--> <!-->13.6 years, illness duration 15.1<!--> <!-->±<!--> <span>11.5 years. 55.8% consumed tobacco. Positive PANSS score was 13.68</span> <!-->±<!--> <!-->6.55, and 20.38<!--> <!-->±<!--> <!-->8.69 in the negative symptoms. CGI was 4.16<!--> <!-->±<!--> <span>2.22 and GAF was 60.00</span> <!-->±<!--> <!-->14.84.</div></div><div><h3>Conclusion</h3><div>The results obtained by this project are expected to contribute toward the understanding of the physiopathology of schizophrenia-spectrum disorders. This will likely aid to personalize treatments in real-world clinical practice, potentially including variables related to intestinal permeability and inflammation.</div></div>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":"18 4","pages":"Pages 281-287"},"PeriodicalIF":2.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135707215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inflammation and weight change related to neurocognitive and functional impairment in diabetes and psychiatric disorders 炎症和体重变化与糖尿病和精神疾病的神经认知和功能障碍有关。
IF 2.8
Spanish Journal of Psychiatry and Mental Health Pub Date : 2025-10-01 Epub Date: 2024-05-11 DOI: 10.1016/j.sjpmh.2024.05.001
Joan Vicent Sánchez-Ortí , Vicent Balanzá-Martínez , Patricia Correa-Ghisays , Gabriel Selva-Vera , Joan Vila-Francés , Rafael Magdalena-Benedito , Constanza San-Martin , Víctor M. Victor , Irene Escribano-Lopez , Antonio Hernandez-Mijares , Juliana Vivas-Lalinde , Benedicto Crespo-Facorro , Rafael Tabarés-Seisdedos
{"title":"Inflammation and weight change related to neurocognitive and functional impairment in diabetes and psychiatric disorders","authors":"Joan Vicent Sánchez-Ortí ,&nbsp;Vicent Balanzá-Martínez ,&nbsp;Patricia Correa-Ghisays ,&nbsp;Gabriel Selva-Vera ,&nbsp;Joan Vila-Francés ,&nbsp;Rafael Magdalena-Benedito ,&nbsp;Constanza San-Martin ,&nbsp;Víctor M. Victor ,&nbsp;Irene Escribano-Lopez ,&nbsp;Antonio Hernandez-Mijares ,&nbsp;Juliana Vivas-Lalinde ,&nbsp;Benedicto Crespo-Facorro ,&nbsp;Rafael Tabarés-Seisdedos","doi":"10.1016/j.sjpmh.2024.05.001","DOIUrl":"10.1016/j.sjpmh.2024.05.001","url":null,"abstract":"<div><h3>Introduction</h3><div>Obesity is a global pandemic associated with various cardio-metabolic and psychiatric disorders. Neurocognitive and functional deficits have been associated with several somatic and psychiatric disorders. Adiposity-related inflammation has recently emerged as a key risk factor for neurocognitive and functional impairments. This prospective transdiagnostic study aimed to investigate the role of adiposity-related inflammatory markers in neurocognitive and functional outcomes associated with weight changes.</div></div><div><h3>Methods</h3><div>Peripheral blood inflammatory and oxidative stress biomarkers and neurocognitive and functional performance were assessed twice over 1 year in 165 individuals, including 30 with schizophrenia, 42 with bipolar disorder, 35 with major depressive disorder, 30 with type 2 diabetes mellitus (T2DM), and 28 healthy controls. Participants were stratified by body mass index into categories of type 2 obesity (T2OB; <em>n</em> <!-->=<!--> <!-->30), type 1 obesity (T1OB; <em>n</em> <!-->=<!--> <!-->42), overweight (OW; <em>n</em> <!-->=<!--> <!-->53), and average weight (NW; <em>n</em> <!-->=<!--> <!-->40). Mixed one-way analysis of covariance and linear and binary logistic regression analyses were performed.</div></div><div><h3>Results</h3><div>Compared with NW, T2OB and T1OB were significantly associated with impaired neurocognitive and functional performance (<em>p</em> <!-->&lt;<!--> <!-->0.01; <em>η</em><sup>2</sup><em>p</em> <!-->=<!--> <!-->0.06–0.12) and higher levels of C-reactive protein and platelets (PLT) (<em>p</em> <!-->&lt;<!--> <!-->0.01; <em>η</em><sup>2</sup><em>p</em> <!-->=<!--> <!-->0.08–0.16), with small-to-moderate effect sizes. IL-6, IL-10, and PLT were key factors for detecting significant weight changes in T1OB and T2OB over time. Regression models revealed that inflammatory and oxidative stress biomarkers and cellular adhesion molecules were significantly associated with neurocognitive and functional performance (<em>p</em> <!-->&lt;<!--> <!-->0.05).</div></div><div><h3>Discussion</h3><div>Obesity is characterized by neurocognitive and functional impairments alongside low-grade systemic inflammation. Adiposity-related inflammatory biomarkers may contribute to neurocognitive and functional decline in individuals with T2DM and psychiatric disorders. Our data suggest that these biomarkers facilitate the identification of specific subgroups of individuals at higher risk of developing obesity.</div></div>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":"18 4","pages":"Pages 256-265"},"PeriodicalIF":2.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140917571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Frontal lobes dysfunction across clinical clusters of acute schizophrenia 急性精神分裂症临床群的额叶功能障碍
IF 2.8
Spanish Journal of Psychiatry and Mental Health Pub Date : 2025-10-01 Epub Date: 2023-09-07 DOI: 10.1016/j.rpsm.2021.12.002
Filippo Corponi , Yana Zorkina , Daniel Stahl , Andrea Murru , Eduard Vieta , Alessandro Serretti , Аnna Morozova , Alexander Reznik , Georgiy Kostyuk , Vladimir Pavlovich Chekhonin
{"title":"Frontal lobes dysfunction across clinical clusters of acute schizophrenia","authors":"Filippo Corponi ,&nbsp;Yana Zorkina ,&nbsp;Daniel Stahl ,&nbsp;Andrea Murru ,&nbsp;Eduard Vieta ,&nbsp;Alessandro Serretti ,&nbsp;Аnna Morozova ,&nbsp;Alexander Reznik ,&nbsp;Georgiy Kostyuk ,&nbsp;Vladimir Pavlovich Chekhonin","doi":"10.1016/j.rpsm.2021.12.002","DOIUrl":"10.1016/j.rpsm.2021.12.002","url":null,"abstract":"<div><h3>Introduction</h3><div><span><span><span>Schizophrenia is a clinical construct comprising manifold phenotypes underlying heterogeneous biological underpinnings. The </span>Positive and Negative Syndrome Scale (PANSS) represents the standard tool in the clinical characterization of patients affected by schizophrenia, allowing to detect different clinical profiles within the disorder. </span>Frontal lobes are a key area of </span>brain dysfunction in schizophrenia. We investigated whether different clinical profiles in acute schizophrenia show differences in frontal lobes dysfunction or not.</div></div><div><h3>Methods</h3><div>We defined PANSS-derived principal components<span> in a sample of 516 acute patients. These components were used as clustering variables in a finite-mixture model. Frontal lobe impairment, measured with the frontal assessment battery (FAB) score, was adjusted for disease duration and compared across the clinical clusters with ANCOVA. A supervised-learning approach was then implemented to reveal most informative PANSS items.</span></div></div><div><h3>Results</h3><div>A three-cluster solution emerged: a first profile with high-moderate expression for the positive and excitability/hostility component; a second profile scoring high on depression/anxiety and low on other components; a third profile, comprising the majority of the study population (74%), with a heavy affection on the negative-disorganization dimensions. After controlling for disease duration, frontal lobe impairment significantly differed across the aforementioned clusters, with the third cluster being the most affected. Two PANSS items presented the highest predictive value for FAB total score.</div></div><div><h3>Conclusions</h3><div>Among negative and disorganization symptoms, “difficulty in abstract thinking” and “lack of spontaneity/flow in conversation” are specifically mapped to higher levels of frontal lobes dysfunction, hinting at similar features with other neurological disorders involving frontal lobes.</div></div>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":"18 4","pages":"Pages 234-240"},"PeriodicalIF":2.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83170867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Breaking down processing speed: Motor and cognitive insights in first-episode psychosis and unaffected first-degree relatives 分解处理速度:首发精神病患者和未受影响的一级亲属的运动和认知洞察力。
IF 2.8
Spanish Journal of Psychiatry and Mental Health Pub Date : 2025-10-01 Epub Date: 2024-06-20 DOI: 10.1016/j.sjpmh.2024.06.002
Ángel Yorca-Ruiz , Rebeca Magdaleno Herrero , Víctor Ortiz García de la Foz , Nancy Murillo-García , Rosa Ayesa-Arriola
{"title":"Breaking down processing speed: Motor and cognitive insights in first-episode psychosis and unaffected first-degree relatives","authors":"Ángel Yorca-Ruiz ,&nbsp;Rebeca Magdaleno Herrero ,&nbsp;Víctor Ortiz García de la Foz ,&nbsp;Nancy Murillo-García ,&nbsp;Rosa Ayesa-Arriola","doi":"10.1016/j.sjpmh.2024.06.002","DOIUrl":"10.1016/j.sjpmh.2024.06.002","url":null,"abstract":"<div><h3>Introduction</h3><div>Processing speed (PS) deficits represent a fundamental aspect of cognitive impairment<span>, evident not only in schizophrenia but also in individuals undergoing their first episode of psychosis (FEP) and their unaffected first-degree relatives. Heterogeneity in tests assessing PS reflects the participation of motor and cognitive subcomponents to varying degrees. We aim to explore differences in performance of the subcomponents of PS in FEP patients, parents, siblings, and controls.</span></div></div><div><h3>Materials and methods</h3><div><span>Results from tests, including Trail Making Test part A and part B, Digit Symbol Coding Test, Grooved Pegboard Test, and Stroop Word and Stroop Color subtests, were obtained from 133 FEP patients, 146 parents, and 202 controls. </span>Exploratory factor analysis (EFA) was employed in controls to establish the structure, followed by confirmatory factor analysis (CFA) to verify if the other groups share this structure.</div></div><div><h3>Results</h3><div>EFA revealed a two-factor model: Factor 1<span> for the motor subcomponent and Factor 2 for the cognitive subcomponent. Subsequently, CFA indicated a good fit for the remaining groups with differences in the relationship between the factors.</span></div></div><div><h3>Conclusions</h3><div>Differences in the relationships of factors within a common structure suggest the involvement of different compensatory strategies among groups, providing insights into the underlying mechanisms of PS deficits in patients and relatives.</div></div>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":"18 4","pages":"Pages 266-273"},"PeriodicalIF":2.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141441234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PRISM-5 update: Adaptation and validation of the Spanish version interview for dual diagnosis assessment based on DSM-5 criteria. PRISM-5更新:基于DSM-5标准的双重诊断评估的西班牙语版访谈的改编和验证。
IF 2.8
Spanish Journal of Psychiatry and Mental Health Pub Date : 2025-09-30 DOI: 10.1016/j.sjpmh.2025.09.002
Claudio Tamarit, Maria Pellicer-Roca, María Alias-Ferrí, Carlos Roncero, Javier Didia-Attas, Francina Fonseca, Julián Andrés Mateus, Joan I Mestre Pintó, Marta Torrens
{"title":"PRISM-5 update: Adaptation and validation of the Spanish version interview for dual diagnosis assessment based on DSM-5 criteria.","authors":"Claudio Tamarit, Maria Pellicer-Roca, María Alias-Ferrí, Carlos Roncero, Javier Didia-Attas, Francina Fonseca, Julián Andrés Mateus, Joan I Mestre Pintó, Marta Torrens","doi":"10.1016/j.sjpmh.2025.09.002","DOIUrl":"10.1016/j.sjpmh.2025.09.002","url":null,"abstract":"<p><strong>Introduction: </strong>Diagnosing individuals with co-occurring substance use and other mental disorders (SUDs and MDs) is challenging due to overlapping symptoms and masking effects. Semi-structured interviews, like the Psychiatric Research Interview for Substance and Mental Disorders (PRISM), are essential for diagnostic accuracy. This study aims to update and validate the Spanish PRISM-IV to DSM-5 criteria, providing evidence of reliability based on its ability to assess Dual Disorders (DDs).</p><p><strong>Material and methods: </strong>The PRISM-5 was translated and culturally adapted to Spanish to ensure equivalence with the original English version. The interview was computerized using BLAISE© software and pilot-tested. A cross-sectional study with patients recruited from specialized treatment centers in Spain and Argentina compared PRISM-5 diagnoses to those established through the Longitudinal, Expert, All Data (LEAD) method, providing evidence of diagnostic agreement through Cohen's kappa coefficient.</p><p><strong>Results: </strong>197 patients were recruited (69% male, mean age=35.6). PRISM-5 showed substantial evidence of diagnostic agreement for most SUDs (k=0.62-0.77), including alcohol, cannabis, cocaine, heroin, sedative, and amphetamine use disorders, with excellent agreement for past heroin use disorder (k=0.83). For MDs, substantial agreement was found for major depression, ADHD and psychotic, panic, and personality disorders (k=0.63-0.73), while moderate agreement was observed for substance-induced and persistent depression (k=0.59-0.60).</p><p><strong>Conclusions: </strong>PRISM-5 provided strong evidence of diagnostic reliability in its Spanish version, with substantial agreement across most diagnoses. Compared to the PRISM-IV, it showed similar evidence of reliability, with some notable improvements in areas such as alcohol and cannabis use disorders. These findings underscore the instrument's robustness and value for diagnosing DDs.</p>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145215073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A population-based screening program provides insights into the characteristics and behaviors of individuals who self-refer for gambling disorder. 一个以人群为基础的筛查项目提供了对自我指涉赌博障碍的个体的特征和行为的见解。
IF 2.8
Spanish Journal of Psychiatry and Mental Health Pub Date : 2025-09-05 DOI: 10.1016/j.sjpmh.2025.07.002
Francisco Ferre, Marisol Roncero, Nestor Szerman, Ignacio Basurte-Villamor, Pablo Vega, Nicolas Nieves, Ignacio Civeira, Celso Arango
{"title":"A population-based screening program provides insights into the characteristics and behaviors of individuals who self-refer for gambling disorder.","authors":"Francisco Ferre, Marisol Roncero, Nestor Szerman, Ignacio Basurte-Villamor, Pablo Vega, Nicolas Nieves, Ignacio Civeira, Celso Arango","doi":"10.1016/j.sjpmh.2025.07.002","DOIUrl":"10.1016/j.sjpmh.2025.07.002","url":null,"abstract":"<p><strong>Introduction: </strong>Since only around 10% of people with gambling disorder (GD) seek professional treatment or attend self-help groups, multiple strategies are needed to improve this rate. The proposal of the Behavioral Addictions Center 'Adcom' (Madrid, Spain) is one such strategy, a pioneering and innovative program aimed at the general population to identify people with addictions such as GD, in an attempt to offer them appropriate evidence-based treatments.</p><p><strong>Materials and methods: </strong>We analyzed information obtained from the first 305 adults who voluntarily sought attention at Adcom for self-referred gambling, and conducted a descriptive, cross-sectional and observational study of this population.</p><p><strong>Results: </strong>A total of 265 of these 305 individuals were tagged as GD and were eventually included in the study, 87.2% of whom were men. The mean age of this sample was 36.9 years old and while 49.8% were treated for self-referred offline gambling addiction, the remaining 50.2% self-referred to online gambling addiction. Other psychopathological symptoms were evident in 57.4% of the participants, with a Global Severity Index T-score of 62.6 (± 12.2). Based on the SCL-90, depression (63.6%), psychoticism (62.6%), anxiety (66.7%) and obsession/compulsion (59.3%) were present in more than half of our participants, while 37.4% were diagnosed with ADHD. A multivariate regression analysis revealed that being born in Spain and excessive Internet use were independent predictors of online gambling addiction.</p><p><strong>Conclusions: </strong>This study of problem gamblers recruited in a non-clinical, self-referred setting confirms that GD is associated with an elevated presence of other mental disorders, identifying predictors of online and offline gambling addiction.</p>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145017049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cognitive discrepancy patterns and their association with psychosocial functioning across affective disorders. 认知差异模式及其与情感性障碍的社会心理功能的关系。
IF 2.8
Spanish Journal of Psychiatry and Mental Health Pub Date : 2025-08-29 DOI: 10.1016/j.sjpmh.2025.05.001
Muriel Vicent-Gil, Maria Serra-Blasco, Joan Trujols, Guillem Navarra-Ventura, Javier de Diego-Adeliño, Dolors Puigdemont, Carlo Alemany, Josefina Pérez, Maria J Portella, Narcís Cardoner
{"title":"Cognitive discrepancy patterns and their association with psychosocial functioning across affective disorders.","authors":"Muriel Vicent-Gil, Maria Serra-Blasco, Joan Trujols, Guillem Navarra-Ventura, Javier de Diego-Adeliño, Dolors Puigdemont, Carlo Alemany, Josefina Pérez, Maria J Portella, Narcís Cardoner","doi":"10.1016/j.sjpmh.2025.05.001","DOIUrl":"10.1016/j.sjpmh.2025.05.001","url":null,"abstract":"<p><strong>Introduction: </strong>Individuals with major depressive disorder (MDD) and bipolar disorder (BD) frequently exhibit a disagreement between self-reported and objectively measured cognitive performance. Research suggests that these cognitive discrepancies may vary across disorders and are not exclusive to a specific diagnosis, potentially being influenced by clinical and sociodemographic factors. Overestimating cognitive abilities is associated with better psychosocial functioning in depression, whereas heightened sensitivity to cognitive deficits correlates with worse functioning. However, these phenomena remain underexplored in both depression and bipolar disorder.</p><p><strong>Materials and methods: </strong>We conducted a cross-sectional study of 200 participants, including 160 patients in full or partial clinical remission (94 with MDD and 66 with BD) and 40 healthy controls. Sociodemographic, clinical, and functional variables were collected, along with both subjective and objective cognitive measures. We conducted a multivariate binary logistic regression to identify factors associated with cognitive discrepancy patterns (under- vs overestimation). Finally, a two-way ANOVA tested the interaction between diagnosis and cognitive discrepancy patterns on psychosocial functioning.</p><p><strong>Results: </strong>Patients with MDD tend to underestimate their cognitive abilities, while bipolar patients often overestimate theirs. Patients with higher depressive symptoms (B=-.045, p=.040) and higher intellectual level (B=-.241, p=<.001) report more subjective cognitive disturbances. Worse psychosocial functioning is not associated with underestimation but rather with the diagnosis itself (F=.63, p=.431), with bipolar disorder patients experiencing the most significant impact on daily functioning.</p><p><strong>Conclusions: </strong>Personalized cognitive assessments, integrating both objective and subjective measures, are of paramount importance to avoid generalizations and to accurately evaluate cognitive symptoms in patients with affective disorders.</p>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144985218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Potential duplicate cases in the official suicide statistics reported by the Spanish National Statistics Institute (INE). 西班牙国家统计局(INE)报告的官方自杀统计数据中可能存在重复病例。
IF 2.8
Spanish Journal of Psychiatry and Mental Health Pub Date : 2025-08-27 DOI: 10.1016/j.sjpmh.2025.07.001
Sergio Sanz Gómez, Julio A Guija, Lucas Giner
{"title":"Potential duplicate cases in the official suicide statistics reported by the Spanish National Statistics Institute (INE).","authors":"Sergio Sanz Gómez, Julio A Guija, Lucas Giner","doi":"10.1016/j.sjpmh.2025.07.001","DOIUrl":"10.1016/j.sjpmh.2025.07.001","url":null,"abstract":"","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144985139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of the SARS-CoV-2 pandemic on pediatric suicide attempts in an emergency department. SARS-CoV-2大流行对急诊科儿科自杀企图的影响
IF 2.8
Spanish Journal of Psychiatry and Mental Health Pub Date : 2025-07-12 DOI: 10.1016/j.sjpmh.2025.04.003
Mar Sabater-Garcia, Jessica Acosta-Cabello, Anna Borja-Lloret, Sandra Ortigosa-Gómez, Amaia Bilbao-Garitagoitia, Mª Ángeles López-Vílchez
{"title":"Impact of the SARS-CoV-2 pandemic on pediatric suicide attempts in an emergency department.","authors":"Mar Sabater-Garcia, Jessica Acosta-Cabello, Anna Borja-Lloret, Sandra Ortigosa-Gómez, Amaia Bilbao-Garitagoitia, Mª Ángeles López-Vílchez","doi":"10.1016/j.sjpmh.2025.04.003","DOIUrl":"10.1016/j.sjpmh.2025.04.003","url":null,"abstract":"","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144639182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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