RSC Applied Polymers最新文献

{"title":"Sonication labile PEG-based hydrogel system for biological component suspension and subsequent degradation†","authors":"Meagan N. Arguien, Joshua T. Kamps, Sarah A. Muth, Marianela Trujillo-Lemon and Christopher N. Bowman","doi":"10.1039/D4LP00161C","DOIUrl":"https://doi.org/10.1039/D4LP00161C","url":null,"abstract":"<p >This work synthesizes poly(ethylene glycol) (PEG) macromers that incorporate a phthalaldehyde moiety located at crosslink junctions. This location facilitates the severing of the polymer network when bond scission of the phthalaldehyde unit occurs with mechanical stimulation. As these networks degrade, the mechanical properties are analyzed to better understand how sonication driven degradation affects a polymer network – specifically looking at the degradation profile in hydrogel systems through the mass loss and storage modulus profiles. Comparison of hydrogels containing phthalaldehyde units with hydrogels that do not have the mechanophore pre- and post-mechanical stimulation provides evidence that the incorporation of the mechanophore at these crosslink junctions reduces the storage modulus by a factor of ten and results in greater than 90% decrease of the gel mass after 15 minutes of probe sonication, leading to breaking the network into soluble daughter fragments. The network degradation conditions of these hydrogels are shown to be compatible with biological component suspension and release for applications such as localized payload release.</p>","PeriodicalId":101139,"journal":{"name":"RSC Applied Polymers","volume":" 6","pages":" 1147-1156"},"PeriodicalIF":0.0,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/lp/d4lp00161c?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142636630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of the cross-linked structures of polymer gels containing iron porphyrins on photoreduction of carbon dioxide†","authors":"Shota Furusawa, Masanori Nagao, Hikaru Matsumoto and Yoshiko Miura","doi":"10.1039/D4LP00135D","DOIUrl":"https://doi.org/10.1039/D4LP00135D","url":null,"abstract":"<p >We prepared polystyrene-based polymer gels containing iron porphyrin and evaluated the effects of the cross-linked structures on the photoreduction of carbon dioxide to carbon monoxide. The amount of generated carbon monoxide was influenced by the diffusion of the substrates into the gel structures.</p>","PeriodicalId":101139,"journal":{"name":"RSC Applied Polymers","volume":" 6","pages":" 1026-1031"},"PeriodicalIF":0.0,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/lp/d4lp00135d?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142636618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cathodic electrodeposition of polymer networks as ultrathin films on 3-D micro-architected electrodes†","authors":"Zhaoyi Zheng, Anton B. Resing, Wenlu Wang and Jörg G. Werner","doi":"10.1039/D4LP00180J","DOIUrl":"https://doi.org/10.1039/D4LP00180J","url":null,"abstract":"<p >Advances in precision coatings are critical in enhancing the functionality of porous materials and the performance of three-dimensionally (3-D) micro-architected devices in applications ranging from molecular sorption and separation to energy storage and conversion. To address this need, we report the cathodic electrodeposition of polymer networks (EPoN) that utilizes the coupling between pre-synthesized polymers with electrochemically active end groups and a complementary crosslinker to form a step-growth polymer network. The electrochemically mediated crosslinking reaction confines the network formation to the electrode surface in a passivating and self-limiting film growth, preventing uncontrolled precipitation and deposition away from the surface. The cathodic electrodeposition is compatible with a variety of conductive substrates, which is demonstrated for 3-D carbons and metals with micron-scale pores of high aspect ratio. The entire pore surface of the 3-D electrodes is enveloped by a conformal polymer thin film that is free of detectable defects and highly electronically insulating for its potential use as an ultrathin artificial electrolyte interphase or solid polymer electrolyte. Since our EPoN concept decouples the polymer functionality from its electrodeposition chemistry, we envision it to be a widely applicable method to coat various conductive non-planar and micro-architected 3-D substrates with polymers of broad functionalities.</p>","PeriodicalId":101139,"journal":{"name":"RSC Applied Polymers","volume":" 6","pages":" 1139-1146"},"PeriodicalIF":0.0,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/lp/d4lp00180j?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142636629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fluorescent histidine-derived biodynamers as biocompatible and highly water-soluble copper(ii)-sensors†","authors":"Lena Zeroug-Metz, Mohamed A. M. Kamal, Justine Bassil, Kalanika Elamaldeniya, Bo Hyun Ryu, Eric Buhler and Sangeun Lee","doi":"10.1039/D4LP00126E","DOIUrl":"https://doi.org/10.1039/D4LP00126E","url":null,"abstract":"<p >Amino-acid derived biodynamers, characterized as dynamic biopolymers, are synthesized under acidic pH conditions through dynamic covalent chemistry (DCC) between amino acid hydrazides and carbazole hexaethylene glycols (CA-HG). In the field of biomedical research, especially for the designs of smart drug delivery systems, DCC has increasingly gained popularity within the last years. Biodynamers possess a range of advantageous properties, such as fluorescence, tunability through amino acid monomer exchange, water solubility, and biocompatibility. These characteristics make them promising materials for a variety of biomedical applications. By leveraging these beneficial traits, biodynamers can be applied as detectors for physiologically important metal ions, utilizing changes in their fluorescence emission upon binding to the DCC framework and polymer's side chains. In this study, we investigated the potential of histidine-based biodynamers (HisBD) for detecting a key biomarker, Cu(<small>II</small>), using <em>in silico</em> simulations and cuvette assays. Our results revealed that HisBD exhibited selective fluorescence in the presence of Cu(<small>II</small>), with approximately 90% quenching of fluorescence due to binding site interactions and side chain effects under physiological conditions. This study broadens the applications of DCC and underscores the potential of HisBD as a candidate for Cu(<small>II</small>) chemosensors, overcoming the limitations of current systems such as limited solubility, sensitivity, and biocompatibility.</p>","PeriodicalId":101139,"journal":{"name":"RSC Applied Polymers","volume":" 6","pages":" 1124-1138"},"PeriodicalIF":0.0,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/lp/d4lp00126e?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142636628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Organo-disulfide-based particles enable controlled stimulus-triggered cleaning of electrode surfaces†","authors":"Hongyi Zhang, Garrett L. Grocke, Samuel S. Kopfinger, Yilin Wang, Arnav Brahmasandra, Randy H. Ewoldt, Stuart J. Rowan and Shrayesh N. Patel","doi":"10.1039/D4LP00250D","DOIUrl":"https://doi.org/10.1039/D4LP00250D","url":null,"abstract":"<p >Electrode fouling resulting in reduced performance is an ongoing challenge in electrochemical flow cells based on redox active polymers (RAPs). An avenue that holds substantial promise yet remains relatively unexplored involves the strategic design of RAPs capable of undergoing electrochemical stimulation to facilitate <em>in situ</em> electrode cleaning within a flow cell. Herein, a new electrode cleaning strategy is demonstrated through the application of redox-active poly(glycidyl methacrylate) particles crosslinked with 2-amino-1,3,4-thiadiazole disulfide (PGMA–ATDDS). The resulting particles can de-crosslink through cleavage of the disulfide bond using stimuli, such as electrochemical reduction or UV photoexcitation. Using a custom flow cell, applying such a stimulus to an ITO electrode artificially fouled with PGMA–ATDDS in the presence of a fluid flow leads to a significant particle removal (80%) that is over six times more efficient relative to the case when no stimulus is applied. Confocal fluorescence imaging of the electrochemically stimulated electrode highlighted localized disulfide reduction of particles near the electrode surface. It is posited that this selective de-crosslinking and concomitant electrolyte swelling at the particle/electrode interface facilitate particle removal in the presence of a fluid flow. In addition, the regeneration of electrode performance upon cleaning was demonstrated through charging of a redox-active particle suspension of poly(vinylbenzyl chloride) functionalized with dimethylaminoferrocene (PVBC–Fc). Upon electrochemical cleaning of the fouled ITO electrode, the accessible charge of PVBC–Fc was statistically equivalent to the accessible charge measured using a pristine ITO electrode. Overall, this study introduces a new approach for leveraging stimulus-responsive chemistries for RAPs to impart inherent functionality to facilitate in-line electrode cleaning in electrochemical flow cells.</p>","PeriodicalId":101139,"journal":{"name":"RSC Applied Polymers","volume":" 6","pages":" 1113-1123"},"PeriodicalIF":0.0,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/lp/d4lp00250d?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142636627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"d-Xylose oxetane copolymers as bioderived and tuneable polyesters for amorphous solid dispersions†","authors":"Ella F. Clark, Alexandra Howard, Sebastian D. Morales Feliu, James F. McCabe, Jonathan C. Burley, Vincenzo Taresco and Antoine Buchard","doi":"10.1039/D4LP00203B","DOIUrl":"https://doi.org/10.1039/D4LP00203B","url":null,"abstract":"<p >The ring-opening copolymerisation of cyclic anhydrides with an oxetane derived from natural monosaccharide <small>D</small>-xylose has been used to synthesise fully biobased water soluble polyesters, which are able to stabilise the amorphous phases of nifedipine and mefenamic acid, enhancing their apparent solubility in water up to 918 and 142% respectively. 2D picolitre-scale inkjet-printing, coupled with polarised optical microscopy (POM) analysis, enabled an initial, high-throughput miniaturised (ng–μg scale) screening of drug formulations. The best formulations were scaled up and analysed by FT-IR spectroscopy and DSC, revealing interactions between the drugs and polymers. Finally, drug dissolution studies demonstrated the effectiveness of the polymers in improving the drugs’ apparent solubility in water. These results showcase the potential of synthetic carbohydrate polymers as excipient for tailored drug formulations.</p>","PeriodicalId":101139,"journal":{"name":"RSC Applied Polymers","volume":" 6","pages":" 1104-1112"},"PeriodicalIF":0.0,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/lp/d4lp00203b?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142636626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nanostructuring niobium oxides using polymer-grafted cellulose nanocrystals and nanofibers as sacrificial scaffolds†","authors":"Yen Theng Cheng, Sandya S. Athukoralalage, Nasim Amiralian, Chris D. Ling and Markus Müllner","doi":"10.1039/D4LP00185K","DOIUrl":"https://doi.org/10.1039/D4LP00185K","url":null,"abstract":"<p >The unique one-dimensional structure and surface functionality of cellulose nanocrystals (CNCs) and cellulose nanofibers (CNFs) render them promising candidates for renewable nanomaterials. Here, we report the template-directed synthesis of highly polycrystalline Nb<small>₂</small>O<small>₅</small> polymorphs using polymer brush-grafted CNCs and CNFs as sacrificial scaffolds. The scaffolds consisted of a CNC or CNF core, from which poly(2-(dimethylamino)ethyl methacrylate) (PDMAEMA) brushes were grafted using surface-initiated atom transfer radical polymerization (SI-ATRP). The nanocellulose-<em>g</em>-PDMAEMA nanoreactors were complexed with a water-soluble Nb<small>₂</small>O<small>₅</small> precursor, ammonium niobate(<small>V</small>) oxalate hydrate (NbO<em>x</em>A), <em>via</em> electrostatic interaction before they were heated to different temperatures to fabricate one-dimensional polycrystalline niobium pentoxides (<em>nc</em>-Nb<small>₂</small>O<small>₅</small> and <em>nf</em>-Nb<small>₂</small>O<small>₅</small>) with controllable polymorphism. Specifically, phase-pure pseudohexagonal Nb<small>₂</small>O<small>₅</small> (TT-Nb<small>₂</small>O<small>₅</small>), orthorhombic Nb<small>₂</small>O<small>₅</small> (T-Nb<small>₂</small>O<small>₅</small>) and monoclinic Nb<small>₂</small>O<small>₅</small> (H-Nb<small>₂</small>O<small>₅</small>) were synthesized. Finally, we show that the polycrystalline <em>nc</em>-Nb<small>₂</small>O<small>₅</small> and <em>nf</em>-Nb<small>₂</small>O<small>₅</small> can function as photocatalysts for decomposing rhodamine B.</p>","PeriodicalId":101139,"journal":{"name":"RSC Applied Polymers","volume":" 1","pages":" 146-155"},"PeriodicalIF":0.0,"publicationDate":"2024-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/lp/d4lp00185k?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143107714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Poly(ionic liquid) ABC triblock and ABCBA pentablock terpolymer electrolytes for lithium metal batteries†","authors":"Dohyun Kim, Rui Sun, Roger Tocchetto, Carl Willis, Bert Krutzer, Frederick L. Beyer and Yossef A. Elabd","doi":"10.1039/D4LP00204K","DOIUrl":"https://doi.org/10.1039/D4LP00204K","url":null,"abstract":"<p >In this study, poly(ionic liquid) (PIL) ABC triblock and ABCBA pentablock terpolymers (PILTTP and PILPTP, respectively) were synthesized to investigate the impact of chain architecture (ABC <em>versus</em> ABCBA) on properties. Specifically, the morphology, ionic conductivity, mechanical properties, electrochemical stability, and lithium metal battery performance of the PILTTP and PILPTP as ternary solid polymer electrolytes (SPEs) containing corresponding lithium salt and ionic liquid (IL) (at various IL concentrations) were measured. Interestingly, the PILPTP SPEs show one order of magnitude higher Young's modulus compared to the PILTTP at the same IL concentration due to bridged conformations and interlocked entanglements of the PILPTP. The improved mechanical properties of the PILPTP SPE lead to enhanced electrochemical stability and stable battery performance over 50 cycles at room temperature, exhibiting dendrite suppressing ability. This study highlights the importance of the symmetric ABCBA structure of PIL multiblock polymers on cycling stability for solid-state lithium metal batteries.</p>","PeriodicalId":101139,"journal":{"name":"RSC Applied Polymers","volume":" 6","pages":" 1091-1103"},"PeriodicalIF":0.0,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/lp/d4lp00204k?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142636625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acidic polymers reversibly deactivate phages due to pH changes†","authors":"Huba L. Marton, Antonia P. Sagona, Peter Kilbride and Matthew I. Gibson","doi":"10.1039/D4LP00202D","DOIUrl":"10.1039/D4LP00202D","url":null,"abstract":"<p >Bacteriophages are promising as therapeutics and biotechnological tools, but they also present a problem for routine and commercial bacterial cultures, where contamination must be avoided. Poly(carboxylic acids) have been reported to inhibit phages’ ability to infect their bacterial hosts and hence offer an exciting route to discover additives to prevent infection. Their mechanism and limitations have not been explored. Here, we report the role of pH in inactivating phages to determine if the polymers are unique or simply acidic. It is shown that lower pH (=3) triggered by either acidic polymers or similar changes in pH using HCl lead to inhibition. There is no inhibitory activity at higher pHs (in growth media). This was shown across a panel of phages and different molecular weights of commercial and controlled-radical polymerization-derived poly(acrylic acid)s. It is shown that poly(acrylic acid) leads to reversible deactivation of phage, but when the pH is adjusted using HCl alone the phage is irreversibly deactivated. Further experiments using metal binders ruled out ion depletion as the mode of action. These results show that polymeric phage inhibitors may work by unique mechanisms of action and that pH alone cannot explain the observed effects whilst also placing constraints on the practical utility of poly(acrylic acid).</p>","PeriodicalId":101139,"journal":{"name":"RSC Applied Polymers","volume":" 6","pages":" 1082-1090"},"PeriodicalIF":0.0,"publicationDate":"2024-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11342163/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142057794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"‘Clickable’ polymeric coatings: from antibacterial surfaces to interfaces with cellular and biomolecular affinity","authors":"Aysun Degirmenci, Rana Sanyal and Amitav Sanyal","doi":"10.1039/D4LP00193A","DOIUrl":"https://doi.org/10.1039/D4LP00193A","url":null,"abstract":"<p >Functional polymeric coatings have become indispensable in various biomedical devices since they provide tailored interfaces with desirable properties that enable such applications. For finding an optimal system with the best performance, adopting a modular approach to interface engineering is essential for practical applications. Efficient functionalization of interfaces with specific (bio)molecules, probes, and bioactive ligands endows these interfaces with desirable properties such as biological sensing, adhesion, wettability, and anti-biofouling. In this context, ‘click’ reactions, including copper-catalyzed azide–alkyne cycloaddition (CuAAC), strain-promoted azide–alkyne cycloaddition (SPAAC), nucleophilic and radical thiol–ene, and Diels–Alder (DA) reactions, emerge as pivotal methods for effective modification of polymer-coated surfaces. This review provides an in-depth overview of utilizing ‘clickable’ group-containing polymeric coatings to create functional interfaces for biomedical applications, with a particular emphasis on antimicrobial surfaces and interfaces conducive to cellular and biomolecular immobilizations. Leveraging the versatility and modularity of surface modifications <em>via</em> ‘click’ chemistry, this review aims to inspire researchers to explore this promising approach for engineering functional polymeric interfaces.</p>","PeriodicalId":101139,"journal":{"name":"RSC Applied Polymers","volume":" 6","pages":" 976-995"},"PeriodicalIF":0.0,"publicationDate":"2024-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/lp/d4lp00193a?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142636623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}