RSC Applied Polymers最新文献_第10页

Virus adsorption and elution using cationic polymer brushes: potential applications for passive sampling in wastewater-based epidemiology† 使用阳离子聚合物刷吸附和洗脱病毒：在基于废水的流行病学被动采样中的潜在应用†。

RSC Applied Polymers Pub Date : 2024-04-02 DOI: 10.1039/D3LP00216K

Junya Uchida, Miaomiao Liu, Shizuka Matsuyama, Hiroyuki Katayama and Takashi Kato

引用次数: 0

Triple click chemistry for crosslinking, stiffening, and annealing of gelatin-based microgels† 用于明胶基微凝胶交联、硬化和退火的三重点击化学反应†。

RSC Applied Polymers Pub Date : 2024-03-28 DOI: 10.1039/D3LP00249G

Chun-Yi Chang, Han Nguyen, Ellen Frahm, Keith Kolaczyk and Chien-Chi Lin

{"title":"Triple click chemistry for crosslinking, stiffening, and annealing of gelatin-based microgels†","authors":"Chun-Yi Chang, Han Nguyen, Ellen Frahm, Keith Kolaczyk and Chien-Chi Lin","doi":"10.1039/D3LP00249G","DOIUrl":"https://doi.org/10.1039/D3LP00249G","url":null,"abstract":"Microgels are spherical hydrogels with physicochemical properties ideal for many biomedical applications. For example, microgels can be used as individual carriers for suspension cell culture or jammed/annealed into granular hydrogels with micron-scale pores highly permissive to molecular transport and cell proliferation/migration. Conventionally, laborious optimization processes are often needed to create microgels with different moduli, sizes, and compositions. This work presents a new microgel and granular hydrogel preparation workflow using gelatin-norbornene-carbohydrazide (GelNB-CH). As a gelatin-derived macromer, GelNB-CH presents cell adhesive and degradable motifs while being amenable to three orthogonal click chemistries, namely the thiol-norbornene photo-click reaction, hydrazone bonding, and the inverse electron demand Diels–Alder (iEDDA) click reaction. The thiol-norbornene photo-click reaction (with thiol-bearing crosslinkers) and hydrazone bonding (with aldehyde-bearing crosslinkers) were used to crosslink the microgels and to realize on-demand microgel stiffening, respectively. The tetrazine-norbornene iEDDA click reaction (with tetrazine-bearing crosslinkers) was used to anneal microgels into granular hydrogels. In addition to materials development, we demonstrated the value of the triple-click chemistry granular hydrogels via culturing human mesenchymal stem cells and pancreatic cancer cells.","PeriodicalId":101139,"journal":{"name":"RSC Applied Polymers","volume":" 4","pages":" 656-669"},"PeriodicalIF":0.0,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/lp/d3lp00249g?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141725719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Inherent limitations of the hydrogen-bonding UPy motif as self-healing functionality for polymer electrolytes† 氢键 UPy 主题作为聚合物电解质自修复功能的固有局限性†。

RSC Applied Polymers Pub Date : 2024-03-22 DOI: 10.1039/D4LP00017J

Cuc Thu Mai, Harish Gudla, Guiomar Hernández, Kristina Edström and Jonas Mindemark

{"title":"Inherent limitations of the hydrogen-bonding UPy motif as self-healing functionality for polymer electrolytes†","authors":"Cuc Thu Mai, Harish Gudla, Guiomar Hernández, Kristina Edström and Jonas Mindemark","doi":"10.1039/D4LP00017J","DOIUrl":"https://doi.org/10.1039/D4LP00017J","url":null,"abstract":"The development of advanced materials displaying reversible functionalities, such as self-healing is particularly desirable for energy storage devices, since the cycle life of many rechargeable batteries is limited due to the irreversible mechanical damages over the cycling processes. Hydrogen-bonding self-healing polymers functionalized with ureido pyrimidinone (UPy) has received great interest for energy storage applications, particularly for polymer electrolytes. Herein, we design a star-branched poly(ε-caprolactone-co-trimethylene carbonate) end-capped with UPy groups for both reinforced mechanical and desired self-healing properties in the polymer electrolytes. Despite the versatile implementation and strong bonding association, the benefits of hydrogen-bonding UPy functionalities are diminished after the dissolution of LiTFSI salt in the self-healing polymer matrix. Experimental analysis and molecular dynamics simulations were performed to gain insight into the dynamics of the self-healing polymer electrolyte system. FTIR shows a dramatic decrease in the intensities of the hydrogen-bonded C<img>O signals belonging to UPy motifs after adding LiTFSI salt, indicative of a significant reduction in the total number of hydrogen-bonding and more loosened cross-linked polymer network. This is also noticed as a simultaneous deterioration of the mechanical properties. Molecular dynamics simulations reveal that the complex interplay of C<img>O--Li+ coordination bonds and hydrogen bonding between TFSI anions and UPy motifs are responsible for the mechanical deterioration of the self-healing polymer electrolytes.","PeriodicalId":101139,"journal":{"name":"RSC Applied Polymers","volume":" 3","pages":" 374-383"},"PeriodicalIF":0.0,"publicationDate":"2024-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/lp/d4lp00017j?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141091265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Valorization of plastic waste via chemical activation and carbonization into activated carbon for functional material applications 通过化学活化和碳化将塑料废弃物转化为活性炭，实现功能材料应用的价值化

RSC Applied Polymers Pub Date : 2024-03-19 DOI: 10.1039/D4LP00016A

Rachel Blanchard and Tizazu H. Mekonnen

{"title":"Valorization of plastic waste via chemical activation and carbonization into activated carbon for functional material applications","authors":"Rachel Blanchard and Tizazu H. Mekonnen","doi":"10.1039/D4LP00016A","DOIUrl":"https://doi.org/10.1039/D4LP00016A","url":null,"abstract":"Addressing the complex issue of plastic waste disposal requires a nuanced approach, as no single solution proves universally effective. This review advocates for a comprehensive strategy, combining mechanical recycling and chemical methods to manage plastic waste while emphasizing the transformative potential of carbonization and activation processes specifically. With a focus on chemical activation, this review explores the synthesis of high surface area activated carbon (AC) from diverse plastic sources including polyesters (e.g., polyethylene terephthalate), polyolefins (e.g., polyethylene, polypropylene), and non-recyclable thermoset resins (e.g., epoxy, phenolics). The resulting AC products exhibit notable potential, with high surface areas exceeding 2000 m2 g−1 in some cases. Furthermore, the adsorptive behavior of the plastic derived ACs are discussed with respect to common pollutants such as dyes and CO2 in addition to emerging pollutants, such as micro/nano-plastics. Overall, this work highlights carbonization and chemical activation as important upcycling methods for plastic wastes that may otherwise end up in landfills or spills into the environment. Given the urgency of plastic waste disposal, it is recommended that the feasibility and scalability of plastic-derived AC production is explored in future work for the potential replacement of conventional AC feedstocks derived from coal or biomass.","PeriodicalId":101139,"journal":{"name":"RSC Applied Polymers","volume":" 4","pages":" 557-582"},"PeriodicalIF":0.0,"publicationDate":"2024-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/lp/d4lp00016a?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141725728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A bioinspired approach to reversibly metal binding interfaces† 可逆金属结合界面的生物启发方法†

RSC Applied Polymers Pub Date : 2024-03-15 DOI: 10.1039/D4LP00010B

Agnes C. Morrissey, Vishakya Jayalatharachchi, Lukas Michalek, Prasanna Egodawatta, Neomy Zaquen, Laura Delafresnaye and Christopher Barner-Kowollik

引用次数: 0

Uniform trehalose nanogels for glucagon stabilization† 用于稳定胰高血糖素的均匀三卤糖纳米凝胶†

RSC Applied Polymers Pub Date : 2024-03-13 DOI: 10.1039/D3LP00226H

Ellie G. Puente, Rajalakshmi P. Sivasankaran, Daniele Vinciguerra, Jane Yang, Haillie-Ann C. Lower, Andrea L. Hevener and Heather D. Maynard

{"title":"Uniform trehalose nanogels for glucagon stabilization†","authors":"Ellie G. Puente, Rajalakshmi P. Sivasankaran, Daniele Vinciguerra, Jane Yang, Haillie-Ann C. Lower, Andrea L. Hevener and Heather D. Maynard","doi":"10.1039/D3LP00226H","DOIUrl":"https://doi.org/10.1039/D3LP00226H","url":null,"abstract":"Glucagon is a peptide hormone that acts via receptor-mediated signaling predominantly in the liver to raise glucose levels by hepatic glycogen breakdown or conversion of noncarbohydrate, 3 carbon precursors to glucose by gluconeogenesis. Glucagon is administered to reverse severe hypoglycemia, a clinical complication associated with type 1 diabetes. However, due to low stability and solubility at neutral pH, there are limitations in the current formulations of glucagon. Trehalose methacrylate-based nanoparticles were utilized as the stabilizing and solubilizing moiety in the system reported herein. Glucagon was site-selectively modified to contain a cysteine at amino acid number 24 to covalently attach to the methacrylate-based polymer containing pyridyl disulfide side chains. PEG2000 dithiol was employed as the crosslinker to form uniform nanoparticles. Glucagon nanogels were monitored in Dulbecco's phosphate-buffered saline (DPBS) pH 7.4 at various temperatures to determine its long-term stability in solution. Glucagon nanogels were stable up to at least 5 months by size uniformity when stored at −20 °C and 4 °C, up to 5 days at 25 °C, and less than 12 hours at 37 °C. When glucagon stability was studied by either HPLC or thioflavin T assays, the glucagon was intact for at least 5 months at −20 °C and 4 °C within the nanoparticles at −20 °C and 4 °C and up to 2 days at 25 °C. Additionally, the glucagon nanogels were studied for toxicity and efficacy using various assays in vitro. The findings indicate that the nanogels were nontoxic to fibroblast cells and nonhemolytic to red blood cells. The glucagon in the nanogels was as active as glucagon alone. These results demonstrate the utility of trehalose nanogels towards a glucagon formulation with improved stability and solubility in aqueous solutions, particularly useful for storage at cold temperatures.","PeriodicalId":101139,"journal":{"name":"RSC Applied Polymers","volume":" 3","pages":" 473-482"},"PeriodicalIF":0.0,"publicationDate":"2024-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/lp/d3lp00226h?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141091297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ultrathin redox active hydrogel electrolytes for high performance flexible supercapacitors† 用于高性能柔性超级电容器的超薄氧化还原活性水凝胶电解质†。

RSC Applied Polymers Pub Date : 2024-03-07 DOI: 10.1039/D4LP00007B

Mengmeng Xun, Xiuting Shi, Haiping Wang, Xiaoyan Li, Wenxing Miao, Xiangbing Wang, Kanjun Sun, Hui Peng, Guofu Ma and Yuxi Xu

{"title":"Ultrathin redox active hydrogel electrolytes for high performance flexible supercapacitors†","authors":"Mengmeng Xun, Xiuting Shi, Haiping Wang, Xiaoyan Li, Wenxing Miao, Xiangbing Wang, Kanjun Sun, Hui Peng, Guofu Ma and Yuxi Xu","doi":"10.1039/D4LP00007B","DOIUrl":"https://doi.org/10.1039/D4LP00007B","url":null,"abstract":"Flexible supercapacitors (FSCs) based on hydrogel electrolytes have the advantages of high ionic conductivity, no liquid leakage, flexibility and versatility, making them the most promising power sources for wearable devices. Herein, a flexible and stretchable, ultrathin polyvinyl alcohol/carboxymethyl chitosan incorporated with a redox active ionic liquid (PVA/CMCS-[ViEtIm][Br]) hydrogel electrolyte is prepared by a facile coating and freezing/thawing method, which is used to improve the practical performance of supercapacitors. The PVA/CMCS-[ViEtIm][Br] hydrogel film has good mechanical properties. More importantly, the redox reaction caused by [ViEtIm][Br] in the hydrogel electrolyte provides a crucial pseudocapacitive contribution to supercapacitors. Thus, the flexible supercapacitor assembled with the PVA/CMCS-[ViEtIm][Br] hydrogel at a thickness of 0.1 mm has an areal specific capacitance of 314.4 mF cm−2 and an energy density of 78.6 μWh cm−2 at 540 μW cm−2, with a capacitance retention of 87.5% after 10 000 charge/discharge cycles. Moreover, the flexible supercapacitor can also exhibit stable performance at different bending angles. This work provides a simple and feasible method for realizing ultra-thin flexible capacitors with high energy density.","PeriodicalId":101139,"journal":{"name":"RSC Applied Polymers","volume":" 3","pages":" 483-489"},"PeriodicalIF":0.0,"publicationDate":"2024-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/lp/d4lp00007b?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141091298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhancing microplastic capture efficiencies with adhesive coatings on stainless-steel filters† 利用不锈钢过滤器上的粘合涂层提高微塑料捕获效率†。

RSC Applied Polymers Pub Date : 2024-03-07 DOI: 10.1039/D3LP00282A

Malavika Ramkumar, Woojung Ji, Henry E. Thurber, Madeline E. Clough, Sarena Chirdon and Anne J. McNeil

引用次数: 0

Triblock copolymer micelles enhance solubility, permeability and activity of a quorum sensing inhibitor against Pseudomonas aeruginosa biofilms† 三嵌段共聚物胶束提高了一种法定量感应抑制剂的可溶性、渗透性和对铜绿假单胞菌生物膜的活性†。

RSC Applied Polymers Pub Date : 2024-02-27 DOI: 10.1039/D3LP00208J

Karolina Kasza, Fadi Soukarieh, Manuel Romero, Kim R. Hardie, Pratik Gurnani, Miguel Cámara and Cameron Alexander

{"title":"Triblock copolymer micelles enhance solubility, permeability and activity of a quorum sensing inhibitor against Pseudomonas aeruginosa biofilms†","authors":"Karolina Kasza, Fadi Soukarieh, Manuel Romero, Kim R. Hardie, Pratik Gurnani, Miguel Cámara and Cameron Alexander","doi":"10.1039/D3LP00208J","DOIUrl":"https://doi.org/10.1039/D3LP00208J","url":null,"abstract":"Antimicrobial resistance is a threat to public health for which new treatments are urgently required. The capability of bacteria to form biofilms is of particular concern as it enables high bacterial tolerance to conventional therapies by reducing drug diffusion through the dense, exopolymeric biofilm matrix and the upregulation of antimicrobial resistance machinery. Quorum sensing (QS), a process where bacteria use diffusible chemical signals to coordinate group behaviour, has been shown to be closely interconnected with biofilm formation and bacterial virulence in many top priority pathogens including Pseudomonas aeruginosa. Inhibition of QS pathways therefore pose an attractive target for new therapeutics. We have recently reported a new series of pqs quorum sensing inhibitors (QSIs) that serve as potentiators for antibiotics in P. aeruginosa infections. The impact on biofilms of some reported QSIs was however hindered by their poor penetration through the bacterial biofilm, limiting the potential for clinical translation. In this study we developed a series of poly(β-amino ester) (PBAE) triblock copolymers and evaluated their ability to form micelles, encapsulate a QSI and enhance subsequent delivery to P. aeruginosa biofilms. We observed that the QSI could be released from polymer micelles, perturbing the pqs pathway in planktonic P. aeruginosa. In addition, one of the prepared polymer variants increased the QSIs efficacy, leading to an enhanced potentiation of ciprofloxacin (CIP) action and therefore improved reduction in biofilm viability, compared to the non-encapsulated QSI. Thus, we demonstrate QSI encapsulation in polymeric particles can enhance its efficacy through improved biofilm penetration.","PeriodicalId":101139,"journal":{"name":"RSC Applied Polymers","volume":" 3","pages":" 444-455"},"PeriodicalIF":0.0,"publicationDate":"2024-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/lp/d3lp00208j?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141091271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chitosan–saccharide conjugates for eradication of Pseudomonas aeruginosa biofilms† 壳聚糖-多糖共轭物用于消除铜绿假单胞菌生物膜†。

RSC Applied Polymers Pub Date : 2024-02-27 DOI: 10.1039/D3LP00263B

Priyanka Sahariah, Francesco Papi, Koi L. Merz, Olafur E. Sigurjonsson, Rikke Loiuse Meyer and Cristina Nativi

{"title":"Chitosan–saccharide conjugates for eradication of Pseudomonas aeruginosa biofilms†","authors":"Priyanka Sahariah, Francesco Papi, Koi L. Merz, Olafur E. Sigurjonsson, Rikke Loiuse Meyer and Cristina Nativi","doi":"10.1039/D3LP00263B","DOIUrl":"https://doi.org/10.1039/D3LP00263B","url":null,"abstract":"The problem of antibiotic resistance has raised serious concerns globally and hence the development of new materials which can combat these drug-resistant strains has gained a great deal of attention. Herein, we report the use of a biocompatible material, chitosan, as a scaffold to graft saccharides which can specifically target Pseudomonas aeruginosa. We realized this by synthesizing N-functionalized chitosan conjugates by coupling chitosan to fucose and galactose moieties which intercept Pseudomonas aeruginosa lectins and target the bacterial biofilms. A series of six conjugates containing similar proportions of cationic and sugar moieties were synthesized by direct modification of the chitosan backbone using a method that is highly efficient and reproducible. The conjugates showed a bactericidal effect against both Gram positive and Gram negative bacterial strains. An investigation into the antibiofilm activity of the conjugates revealed the optimum combination of the type and positioning of the functionalities that were highly effective in eradicating Pseudomonas aeruginosa biofilms. 2D and 3D imaging of the conjugate-treated biofilms using confocal laser scanning microscopy (CLSM) allowed us to determine that the conjugates not only acted on the surface but also dispersed into deep layers of the biofilm. Interaction between the conjugates and individual bacterial cells in the biofilm was further confirmed by fluorescence labelling of the conjugates and imaging by CLSM.","PeriodicalId":101139,"journal":{"name":"RSC Applied Polymers","volume":" 3","pages":" 461-472"},"PeriodicalIF":0.0,"publicationDate":"2024-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/lp/d3lp00263b?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141091273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0