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Combretum micranthum G. Don (Combretaceae): its physiological effects on renal tubular function and blood pressure 紫菀科紫菀：对肾小管功能和血压的生理影响
Pharmacological Research - Natural Products Pub Date : 2026-06-01 Epub Date: 2026-06-30 DOI: 10.1016/j.prenap.2026.100647
Maïmouna Touré, Serge Manga, Mouhamadou A. Sakho, Ibrahima Diouf, Alioune D. Fall, Sidy M. Seck
{"title":"Combretum micranthum G. Don (Combretaceae): its physiological effects on renal tubular function and blood pressure","authors":"Maïmouna Touré, Serge Manga, Mouhamadou A. Sakho, Ibrahima Diouf, Alioune D. Fall, Sidy M. Seck","doi":"10.1016/j.prenap.2026.100647","DOIUrl":"10.1016/j.prenap.2026.100647","url":null,"abstract":"","PeriodicalId":101014,"journal":{"name":"Pharmacological Research - Natural Products","volume":"11 ","pages":"Article 100647"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148565868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Carvacrol ameliorates endothelial dysfunction in a D-galactose-induced aging model 在d -半乳糖诱导的衰老模型中，香芹酚可改善内皮功能障碍
Pharmacological Research - Natural Products Pub Date : 2026-06-01 Epub Date: 2026-06-30 DOI: 10.1016/j.prenap.2026.100717
Isac Medeiros
{"title":"Carvacrol ameliorates endothelial dysfunction in a D-galactose-induced aging model","authors":"Isac Medeiros","doi":"10.1016/j.prenap.2026.100717","DOIUrl":"10.1016/j.prenap.2026.100717","url":null,"abstract":"","PeriodicalId":101014,"journal":{"name":"Pharmacological Research - Natural Products","volume":"11 ","pages":"Article 100717"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148566138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Contribution To Antihypertensive Phytotherapy: Surveys Of Traditional Healers And Herbalists In Dakar And Thies (Senegal) 植物疗法对降压的贡献：对达喀尔和提斯（塞内加尔）传统治疗师和草药医师的调查
Pharmacological Research - Natural Products Pub Date : 2026-06-01 Epub Date: 2026-06-30 DOI: 10.1016/j.prenap.2026.100685
Kady Diatta, William Diatta, Amadou Ibrahima Mbaye, Abdou SARR, Serigne Ibra Mbacké DIENG, Alioune Fall
{"title":"Contribution To Antihypertensive Phytotherapy: Surveys Of Traditional Healers And Herbalists In Dakar And Thies (Senegal)","authors":"Kady Diatta, William Diatta, Amadou Ibrahima Mbaye, Abdou SARR, Serigne Ibra Mbacké DIENG, Alioune Fall","doi":"10.1016/j.prenap.2026.100685","DOIUrl":"10.1016/j.prenap.2026.100685","url":null,"abstract":"","PeriodicalId":101014,"journal":{"name":"Pharmacological Research - Natural Products","volume":"11 ","pages":"Article 100685"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148572819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endophytic Aspergillus Sp. from Mangifera indica as a source of antibacterial, antioxidant and antiviral metabolites 芒果内生曲霉作为抗菌、抗氧化和抗病毒代谢物的来源
Pharmacological Research - Natural Products Pub Date : 2026-06-01 Epub Date: 2026-06-30 DOI: 10.1016/j.prenap.2026.100687
U. Chigozie Victor, O. Esimone Charles
{"title":"Endophytic Aspergillus Sp. from Mangifera indica as a source of antibacterial, antioxidant and antiviral metabolites","authors":"U. Chigozie Victor, O. Esimone Charles","doi":"10.1016/j.prenap.2026.100687","DOIUrl":"10.1016/j.prenap.2026.100687","url":null,"abstract":"","PeriodicalId":101014,"journal":{"name":"Pharmacological Research - Natural Products","volume":"11 ","pages":"Article 100687"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148573256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Molecular Docking and Antihyperglycemic Effect of Stilbenes Derived from Anthraldehyde and Benzaldehyde 蒽醛和苯甲醛二苯乙烯类化合物的分子对接及降糖作用
Pharmacological Research - Natural Products Pub Date : 2026-06-01 Epub Date: 2026-06-30 DOI: 10.1016/j.prenap.2026.100673
Fatimata Seydy Ball, Ndèye Fatim Fall, Malamine Mansaly, Charlot Diatta, Oumar Sambou, Mamadou Fodé Camara, El Hadji Dione, Mouhamadou Thiam, Faty Keita, Yancouba Cheikh Diedhiou, Abdoulaye Gassama, Guata Yoro Sy
{"title":"Molecular Docking and Antihyperglycemic Effect of Stilbenes Derived from Anthraldehyde and Benzaldehyde","authors":"Fatimata Seydy Ball, Ndèye Fatim Fall, Malamine Mansaly, Charlot Diatta, Oumar Sambou, Mamadou Fodé Camara, El Hadji Dione, Mouhamadou Thiam, Faty Keita, Yancouba Cheikh Diedhiou, Abdoulaye Gassama, Guata Yoro Sy","doi":"10.1016/j.prenap.2026.100673","DOIUrl":"10.1016/j.prenap.2026.100673","url":null,"abstract":"","PeriodicalId":101014,"journal":{"name":"Pharmacological Research - Natural Products","volume":"11 ","pages":"Article 100673"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148573291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Phytotherapy Anti-Diabetic: Ethnobotanical Surveys among in the District of Mbour (Senegal) 植物疗法抗糖尿病：塞内加尔Mbour地区的民族植物学调查
Pharmacological Research - Natural Products Pub Date : 2026-06-01 Epub Date: 2026-06-30 DOI: 10.1016/j.prenap.2026.100686
Kady Diatta
{"title":"Phytotherapy Anti-Diabetic: Ethnobotanical Surveys among in the District of Mbour (Senegal)","authors":"Kady Diatta","doi":"10.1016/j.prenap.2026.100686","DOIUrl":"10.1016/j.prenap.2026.100686","url":null,"abstract":"","PeriodicalId":101014,"journal":{"name":"Pharmacological Research - Natural Products","volume":"11 ","pages":"Article 100686"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148573255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Phytochemical profiling and anticandidal potential of the marine red alga Gracilaria pudumadamensis 海洋红藻的植物化学特征及其抗刺激素潜力
Pharmacological Research - Natural Products Pub Date : 2026-06-01 Epub Date: 2026-05-24 DOI: 10.1016/j.prenap.2026.100777
Priyanka Karuppanagoundar Rajan , Rajaram Rajendran , Deep Dey Sarkar , Prabhu Kolandhasamy , Mariadoss Arokia Vijaya Anand , Juyeon Lee , Kwang-sun Kim
{"title":"Phytochemical profiling and anticandidal potential of the marine red alga Gracilaria pudumadamensis","authors":"Priyanka Karuppanagoundar Rajan ,&nbsp;Rajaram Rajendran ,&nbsp;Deep Dey Sarkar ,&nbsp;Prabhu Kolandhasamy ,&nbsp;Mariadoss Arokia Vijaya Anand ,&nbsp;Juyeon Lee ,&nbsp;Kwang-sun Kim","doi":"10.1016/j.prenap.2026.100777","DOIUrl":"10.1016/j.prenap.2026.100777","url":null,"abstract":"<div><div>Red marine algae are prolific sources of bioactive metabolites with untapped antimicrobial properties. This study evaluated the anticandidal efficacy and phytochemical profile of <em>Gracilaria pudumadamensis</em>, a red alga collected from the Gulf of Mannar, Southeast coast of India. Sequential extracts were prepared using six solvents of varying polarities: acetone, methanol, ethyl acetate, hexane, aqueous, and dimethyl sulfoxide (DMSO). Antimicrobial susceptibility was assessed against five <em>Candida</em> species using the agar-well diffusion method. The chemical landscape of the alga was characterized using qualitative phytochemical assays, Fourier-transform infrared (FT-IR) spectroscopy, and Gas Chromatography-Mass Spectrometry (GC–MS). The acetone, methanol, and ethyl acetate extracts exhibited potent inhibitory activity, particularly against <em>C. krusei</em> (22 mm zone of inhibition) and <em>C. parapsilosis</em> (21 mm). In contrast, the aqueous and hexane extracts showed minimal activity. Phytochemical screening confirmed the presence of a diverse array of secondary metabolites, including alkaloids, terpenoids, flavonoids, and phenols. FT-IR analysis identified key functional groups, such as carboxylic acids, alcohols, and amines, whereas GC–MS profiling revealed a complex mixture of bioactive compounds, including ɣ-sitosterol, cholesterol derivatives, and fatty acid esters. Notably, the ethyl acetate extract exhibited the highest diversity of metabolites. These findings suggest that <em>G. pudumadamensis</em> is a rich source of antifungal metabolites. Its broad-spectrum activity against <em>Candida</em> species positions this seaweed as a promising candidate for developing novel natural therapeutic agents to combat fungal infections.</div></div>","PeriodicalId":101014,"journal":{"name":"Pharmacological Research - Natural Products","volume":"11 ","pages":"Article 100777"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148184127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diuretic Effects Of Trichilia emetica Vahl (Meliaceae) Extracts On Wistar Rats 吐毛毛菌提取物对Wistar大鼠的利尿作用
Pharmacological Research - Natural Products Pub Date : 2026-06-01 Epub Date: 2026-06-30 DOI: 10.1016/j.prenap.2026.100633
Djoupo A P, Dere K.A.L, Tiahou G.G
{"title":"Diuretic Effects Of Trichilia emetica Vahl (Meliaceae) Extracts On Wistar Rats","authors":"Djoupo A P,&nbsp;Dere K.A.L,&nbsp;Tiahou G.G","doi":"10.1016/j.prenap.2026.100633","DOIUrl":"10.1016/j.prenap.2026.100633","url":null,"abstract":"","PeriodicalId":101014,"journal":{"name":"Pharmacological Research - Natural Products","volume":"11 ","pages":"Article 100633"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148565205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optimized fermentation of endophytic extracts from Ageratum conyzoides L. (Asteraceae) yields novel antimicrobial activity against four multidrug-resistant bacteria 菊科植物Ageratum conyzoides L.内生提取物的优化发酵对四种多重耐药细菌产生了新的抗菌活性
Pharmacological Research - Natural Products Pub Date : 2026-06-01 Epub Date: 2026-06-30 DOI: 10.1016/j.prenap.2026.100703
Kouemo motse Dorgelesse Francine Antoinette
{"title":"Optimized fermentation of endophytic extracts from Ageratum conyzoides L. (Asteraceae) yields novel antimicrobial activity against four multidrug-resistant bacteria","authors":"Kouemo motse Dorgelesse Francine Antoinette","doi":"10.1016/j.prenap.2026.100703","DOIUrl":"10.1016/j.prenap.2026.100703","url":null,"abstract":"","PeriodicalId":101014,"journal":{"name":"Pharmacological Research - Natural Products","volume":"11 ","pages":"Article 100703"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148565212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
India’s Leadership in Integrative Medicine: Bridging Traditional Knowledge and Modern Pharmacology for Global Health 印度在综合医学方面的领导地位：为全球健康架起传统知识和现代药理学的桥梁
Pharmacological Research - Natural Products Pub Date : 2026-06-01 Epub Date: 2026-06-30 DOI: 10.1016/j.prenap.2026.100708
Arun Chandan
{"title":"India’s Leadership in Integrative Medicine: Bridging Traditional Knowledge and Modern Pharmacology for Global Health","authors":"Arun Chandan","doi":"10.1016/j.prenap.2026.100708","DOIUrl":"10.1016/j.prenap.2026.100708","url":null,"abstract":"","PeriodicalId":101014,"journal":{"name":"Pharmacological Research - Natural Products","volume":"11 ","pages":"Article 100708"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148565294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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