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Severe byssinosis with Cor pulmonale and pulmonary arterial hypertension-textile industry: A case report 纺织工业重度肺心病合并肺动脉高压1例

Medical Reports Pub Date : 2025-06-06 DOI: 10.1016/j.hmedic.2025.100280

A. Hemalatha , Gooty Shanaz , J.M. Bhavana , Mohammed Azhar Hussain , B.N. Raghavendra Prasad

{"title":"Severe byssinosis with Cor pulmonale and pulmonary arterial hypertension-textile industry: A case report","authors":"A. Hemalatha , Gooty Shanaz , J.M. Bhavana , Mohammed Azhar Hussain , B.N. Raghavendra Prasad","doi":"10.1016/j.hmedic.2025.100280","DOIUrl":"10.1016/j.hmedic.2025.100280","url":null,"abstract":"<div><div>Byssinosis is an occupational respiratory disease caused by prolonged exposure to cotton dust. It is a significant health concern in the textile industry, particularly in developing countries, and may lead to severe complications if undiagnosed and untreated. We report the case of a 47-year-old Indian male textile worker with advanced Byssinosis, presenting with progressive breathlessness, wheezing, and a two-year history of Cor-Pulmonale and Pulmonary Arterial Hypertension. Clinical findings included clubbing, bilateral pedal edema, and oxygen desaturation (75 %). Treatment involved oxygen therapy, bronchodilators, corticosteroids, and supportive care, with significant symptomatic improvement. This case discusses the severe consequences of chronic Byssinosis due to prolonged occupational exposure. It emphasizes the importance of early detection and preventive strategies, such as personal protective equipment and workplace safety regulations, to mitigate disease progression. Effective management of Byssinosis requires a multifaceted approach to occupational health. Strong preventive measures, early and accurate diagnosis, and evidence-based treatments are essential, particularly in the textile industry.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"13 ","pages":"Article 100280"},"PeriodicalIF":0.0,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144243113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gastric siderosis in the setting of oral iron intake- A Case report and literature review 口服铁摄入环境下的胃黄铁矿病- 1例报告并文献复习

Medical Reports Pub Date : 2025-06-06 DOI: 10.1016/j.hmedic.2025.100268

Bipneet Singh , Muhammad Zarrar Khan , Palak Patel Rodriguez , Beena Ahsan , Jason Schairer

引用次数: 0

Adolescent HSP: A case report from a South Indian tertiary hospital 青少年热休克：南印度某三级医院一例报告

Medical Reports Pub Date : 2025-06-06 DOI: 10.1016/j.hmedic.2025.100281

S. Maragatham , Christinal Thomas , Duraisami Dhamodharan

引用次数: 0

A case of cutaneous tuberculosis with two distinct types of lesions 皮肤结核伴两种不同类型病变的病例

Medical Reports Pub Date : 2025-06-06 DOI: 10.1016/j.hmedic.2025.100275

Seher Bostancı , Kübra Gündüz , Gizem Nur Öztürk , Bilge Ayça Kırmızı , Aylin Okçu Heper

引用次数: 0

Neonatal left ventricular non-compaction: A case with significantly elevated non-compacted to compacted myocardium ratio 新生儿左心室非压实：一例明显升高的非压实心肌与压实心肌之比

Medical Reports Pub Date : 2025-06-06 DOI: 10.1016/j.hmedic.2025.100278

Saja Karaja , Shahed Karaja , Khayry Al-Shami , William Borghol , Saleh Takkem

引用次数: 0

Rare coinheritance of HbQ India trait and sickle cell trait (HbS): A novel co-inheritance documented in pregnancy HbQ印度性状和镰状细胞性状（HbS）的罕见共遗传：妊娠中记录的一种新的共遗传

Medical Reports Pub Date : 2025-06-05 DOI: 10.1016/j.hmedic.2025.100279

Kartavya Kumar Verma

{"title":"Rare coinheritance of HbQ India trait and sickle cell trait (HbS): A novel co-inheritance documented in pregnancy","authors":"Kartavya Kumar Verma","doi":"10.1016/j.hmedic.2025.100279","DOIUrl":"10.1016/j.hmedic.2025.100279","url":null,"abstract":"<div><div>Globally, hemoglobinopathies are among the most widespread inherited genetic disorders affecting red blood cells. However, the co-inheritance of HbQ India and HbS is a rare occurrence and has been infrequently reported in the medical literatures. Our case study describes a 38-year-old pregnant woman with sickle cell trait along with HbQ India co-inheritance. We hypothesized that, owing to the absence of changes in charge or morphology of red blood cells, the HBQ India trait whether expressed independently or through co-inheritance does not lead to hemolytic anemia. In this case, the hemogram findings revealed pregnancy-associated iron deficiency anemia, with no severe hemolytic complications experienced during the eighth month of pregnancy. No cases have been reported involving this co-inheritance during pregnancy, making this case particularly unique and insightful regarding its implications in that context. Investigating these co-inheritances appears feasible in regions with a high incidence of sickle cell disease, such as central India, particularly in Chhattisgarh. However, to date, no significant hemolytic activity has been reported in the absence of any secondary causes related to this condition, indicating a need for further research.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"13 ","pages":"Article 100279"},"PeriodicalIF":0.0,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144222018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Endoscope-assisted suturectomy for craniosynostosis in a resource-limited setting: A pilot case study in Peshawar 在资源有限的情况下，内窥镜辅助缝合术治疗颅缝闭合：白沙瓦的试点案例研究

Medical Reports Pub Date : 2025-06-05 DOI: 10.1016/j.hmedic.2025.100277

Adil Ahmed , Adnan Khan , Bashir Ahmad

{"title":"Endoscope-assisted suturectomy for craniosynostosis in a resource-limited setting: A pilot case study in Peshawar","authors":"Adil Ahmed , Adnan Khan , Bashir Ahmad","doi":"10.1016/j.hmedic.2025.100277","DOIUrl":"10.1016/j.hmedic.2025.100277","url":null,"abstract":"<div><h3>Introduction</h3><div>Unicoronal craniosynostosis is a congenital condition where one of the coronal sutures in the skull fuses prematurely, leading to asymmetric head shape and facial deformities. This condition often results in a noticeable abnormality in head and facial features, which can impact both appearance and neurological development if not treated on time.</div></div><div><h3>Case</h3><div>We present a case of a 4-month-old female infant with left-sided unicoronal craniosynostosis who presented to Northwest General Hospital and Research Centre with abnormal head shape. After clinical examination showed unicoronal craniosynostosis which was investigated with a 3D CT scan that confirmed the diagnosis. She underwent endoscope-assisted suturectomy, a less invasive technique compared to traditional open surgery. A 3cm incision was made, followed by resection of a 1.5cm wide strip of bone from Anterior fontanelle down to the squamosal suture. Post-operatively, she spent 24hours in the pediatric ICU as part of protocol, received IV fluids, pain management, and antibiotics. She was discharged the next day. Two weeks following the surgery Helmet therapy was started which was continued for six months resulting in significant improvement in her head shape and facial asymmetry.</div></div><div><h3>Conclusion</h3><div>Unlike the traditional approach, which requires longer scalp incisions and results in longer operative time, longer hospital stays, higher blood loss, and increased risks of complication, the endoscopic method involves entirely the opposite of those, a smaller incision, lesser operative time, hospital stay, bleeding, and low risks of complication. This minimally invasive approach allows for quicker recovery, shorter hospital stays, and improved cosmetic outcomes and to the best of our knowledge endoscope assisted suturectomy for craniosynostosis has not been done in this region before.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"13 ","pages":"Article 100277"},"PeriodicalIF":0.0,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144230291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rapid diagnosis of gastrointestinal perforated viscus in pediatrics: Role of point-of-care ultrasonography 儿科胃肠道穿孔的快速诊断：即时超声检查的作用

Medical Reports Pub Date : 2025-06-05 DOI: 10.1016/j.hmedic.2025.100273

Abdulaziz Hussein

引用次数: 0

Adult-onset still's disease with atypical presentation: A case report 表现不典型的成人发病still病1例报告

Medical Reports Pub Date : 2025-06-04 DOI: 10.1016/j.hmedic.2025.100272

Sila Mateo Faxas , Kim Yen Thi Nguyen

{"title":"Adult-onset still's disease with atypical presentation: A case report","authors":"Sila Mateo Faxas , Kim Yen Thi Nguyen","doi":"10.1016/j.hmedic.2025.100272","DOIUrl":"10.1016/j.hmedic.2025.100272","url":null,"abstract":"<div><div>Adult-Onset Still's Disease (AOSD) is a rare systemic inflammatory disorder with diagnostic challenges due to its non-specific symptoms. This case presents a rarely documented manifestation of sensorineural hearing loss, while demonstrating the utility of novel biomarker interleukin-18 (IL-18) for diagnosis and successful management with modern biologic therapy. The patient initially presented with persistent sore throat, generalized weakness, diffuse synovitis, and an atypical urticarial rash. Notably, he developed left-sided hearing loss. Laboratory findings showed elevated inflammatory markers, including white blood cell count, liver enzymes, creatine kinase, C-reactive protein, erythrocyte sedimentation rate, and ferritin. Elevated interleukin-18 (IL-18) levels played a crucial role in confirming the diagnosis. After a six-year diagnostic journey, treatment progressed from high-dose steroids to biologic therapies. While the patient showed intolerance to Anakinra, he achieved remission with Canakinumab. This case underscores the importance of recognizing uncommon AOSD manifestations such as hearing loss, and demonstrates how novel biomarkers and targeted biologic therapies can improve diagnosis and management of this complex disorder. The case also suggests potential environmental triggers in AOSD, as symptom exacerbation occurred with alcohol and marijuana use.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"13 ","pages":"Article 100272"},"PeriodicalIF":0.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144243112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intraventricular neurocysticercosis-induced obstructive hydrocephalus: A case report of cyst migration and multidisciplinary management 脑室内神经囊虫引起的阻塞性脑积水：囊肿迁移和多学科治疗1例报告

Medical Reports Pub Date : 2025-06-04 DOI: 10.1016/j.hmedic.2025.100274

Syed H. Ali , Umer Khan , Youssef Abdullah , Haritha Saikumar

引用次数: 0