IJID One Health最新文献_第2页

Deciphering the dynamics of Lassa fever outbreak in Edo State, Nigeria: A 3-year study of the epidemiologic patterns, severity profiles, and clinical management 解读尼日利亚埃多州拉沙热暴发动态：流行病学模式、严重程度概况和临床管理的3年研究

IJID One Health Pub Date : 2025-03-17 DOI: 10.1016/j.ijidoh.2025.100059

Simeon Cadmus , Emmanuel Awosanya , Paul M. Iziomo , Samuel Owoicho , Stephenson B. Ojeifo , Judah Moyin-Jesu , Olalekan Taiwo , Eniola Cadmus , Danny Akhere Asogun , Oyewale Tomori

{"title":"Deciphering the dynamics of Lassa fever outbreak in Edo State, Nigeria: A 3-year study of the epidemiologic patterns, severity profiles, and clinical management","authors":"Simeon Cadmus , Emmanuel Awosanya , Paul M. Iziomo , Samuel Owoicho , Stephenson B. Ojeifo , Judah Moyin-Jesu , Olalekan Taiwo , Eniola Cadmus , Danny Akhere Asogun , Oyewale Tomori","doi":"10.1016/j.ijidoh.2025.100059","DOIUrl":"10.1016/j.ijidoh.2025.100059","url":null,"abstract":"<div><h3>Objectives</h3><div>Nigeria has the highest prevalence of Lassa fever (LF) in West Africa, with Edo State being a high-burden area. This study describes the epidemiology and management of LF in Edo State.</div></div><div><h3>Methods</h3><div>A desk analysis of LF cases from the Irrua Specialist Teaching Hospital (ISTH) records from January 2021 to November 2023 was conducted. The outcome variables were case outcome and severity, classified using the 2018 Nigeria Centre for Disease Control and Prevention LF guide. Bivariate and logistic regression analyses were conducted at α <0.05.</div></div><div><h3>Results</h3><div>Of the 10,432 suspected cases, 1296 (12.4 %) were confirmed, with 964 (74.4 %) occurring during the dry season. The median age was 26 (interquartile range 15–40) years, and 687 (53.0 %) were male. The location distribution pattern of the confirmed cases was clustered, with one-third (34.3 %) from Etsako West. Older age (adjusted odds ratio 2.2, 95 % confidence interval: 1.2–4.0) and more than five symptoms (adjusted odds ratio 9.5, 95 % confidence interval: 6.9–13.1) were associated with severe LF and increased odds of in-hospital death. Hospital presentation time was not associated with LF severity or outcomes. LF confirmation at ISTH was within 24 hours.</div></div><div><h3>Conclusions</h3><div>Older patients with more than five symptoms should be prioritized in LF management, and the ISTH-LF care algorithm is effective.</div></div>","PeriodicalId":100655,"journal":{"name":"IJID One Health","volume":"7 ","pages":"Article 100059"},"PeriodicalIF":0.0,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143838226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An outbreak of canine coronavirus type 2 in captive snow leopards (Panthera uncia) demonstrates a possible role for felids as mixing vessels for alphacoronaviruses 在圈养雪豹（Panthera uncia）中爆发的犬冠状病毒2型暴发表明，猫科动物可能是冠状病毒的混合容器

IJID One Health Pub Date : 2025-03-04 DOI: 10.1016/j.ijidoh.2025.100057

Ximena A. Olarte-Castillo , Abigail B. Schlecht , Paul P. Calle , Gary R. Whittaker

{"title":"An outbreak of canine coronavirus type 2 in captive snow leopards (Panthera uncia) demonstrates a possible role for felids as mixing vessels for alphacoronaviruses","authors":"Ximena A. Olarte-Castillo , Abigail B. Schlecht , Paul P. Calle , Gary R. Whittaker","doi":"10.1016/j.ijidoh.2025.100057","DOIUrl":"10.1016/j.ijidoh.2025.100057","url":null,"abstract":"<div><h3>Objectives</h3><div><em>Alphacoronavirus-1</em> comprises a set of viruses that are highly recombinogenic, including feline coronavirus (FCoV) type 2 (FCoV-2), a recombinant genotype of FCoV type 1, and canine coronavirus type 2 (CCoV-2). To understand the origin of novel recombinant variants, it is crucial to identify hosts susceptible to multiple alphacoronaviruses. The receptor for FCoV-2 and CCoV-2 is aminopeptidase N (APN), with the APN of the domestic cat allowing entry of FCoV-2 and CCoV-2. However, natural infection with CCoV-2 has been reported exclusively in canids.</div></div><div><h3>Methods</h3><div>We investigated an outbreak of CCoV-2 in captive snow leopards (<em>Panthera uncia</em>). We assessed the genetic diversity of the APN of five wild Asian felid species to evaluate their susceptibility to CCoV-2 and FCoV-2.</div></div><div><h3>Results</h3><div>The whole genome of CCoV-2 was sequenced from the feces of the snow leopards. It is closely related to pathogenic variants reported in domestic dogs in the United States and Europe. The APN of the wild felids is highly similar to the APN of the domestic cat.</div></div><div><h3>Conclusions</h3><div>This study provides the first genetic evidence of CCoV-2 infection in a felid and predicts that wild felids may be susceptible to FCoV-2 and CCoV-2. Therefore, felids may play a central role in the emergence of recombinant alphacoronavirus.</div></div>","PeriodicalId":100655,"journal":{"name":"IJID One Health","volume":"7 ","pages":"Article 100057"},"PeriodicalIF":0.0,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143706303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reviewer Thank You List, 2024 审稿人致谢单，2024年

IJID One Health Pub Date : 2025-03-01 DOI: 10.1016/S2949-9151(25)00010-1

引用次数: 0

Evidence of dengue virus exposure and associated risk factors in Rwanda 卢旺达登革热病毒暴露和相关危险因素的证据

IJID One Health Pub Date : 2025-03-01 DOI: 10.1016/j.ijidoh.2025.100056

Vincent Rusanganwa , Brenda Bainda , Yong-Dae Gwon , Maud Mutsaers , Aron Sasu , Eric Seruyange , Sanctus Musafiri , Olivia Wesula Lwande , Magnus Evander

{"title":"Evidence of dengue virus exposure and associated risk factors in Rwanda","authors":"Vincent Rusanganwa , Brenda Bainda , Yong-Dae Gwon , Maud Mutsaers , Aron Sasu , Eric Seruyange , Sanctus Musafiri , Olivia Wesula Lwande , Magnus Evander","doi":"10.1016/j.ijidoh.2025.100056","DOIUrl":"10.1016/j.ijidoh.2025.100056","url":null,"abstract":"<div><h3>Objectives</h3><div>Dengue virus (DENV) is a global public health concern owing to its widespread distribution, significant morbidity, and potentially severe outcomes. Although not yet reported in Rwanda, this study aimed to explore the DENV seroprevalence in selected health facilities.</div></div><div><h3>Methods</h3><div>Serum samples from 2286 patients who visited 11 health facilities nationwide were investigated for DENV and Zika virus immunoglobulin G. Bivariate and multivariate logistic regression analyses were performed to determine the predictors.</div></div><div><h3>Results</h3><div>The DENV seroprevalence was 30.4 %, but Zika virus immunoglobulin G was not detected. Participants’ mean age was 40.5 ± 16.3 years; 62.2 % were females and 37.8 % were males. In total, 85.8 % were farmers, 4.7 % were office workers, and 3 % were vocational professionals. Farmers had a higher risk of past DENV infections than other professionals. No significant differences in past infections were observed between sexes or age groups.</div></div><div><h3>Conclusions</h3><div>These findings indicate past DENV infections in Rwanda, highlighting the need for DENV surveillance and enhanced diagnostic capacity. Strengthening these efforts will help prevent infectious diseases, reduce unnecessary treatments, and mitigate the risk of antimicrobial resistance.</div></div>","PeriodicalId":100655,"journal":{"name":"IJID One Health","volume":"6 ","pages":"Article 100056"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143592501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Global expansion of Aedes mosquitoes and their role in the transboundary spread of emerging arboviral diseases: A comprehensive review 伊蚊的全球扩张及其在新发虫媒病毒性疾病跨界传播中的作用：综述

IJID One Health Pub Date : 2025-03-01 DOI: 10.1016/j.ijidoh.2025.100058

Ebrahim Abbasi

{"title":"Global expansion of Aedes mosquitoes and their role in the transboundary spread of emerging arboviral diseases: A comprehensive review","authors":"Ebrahim Abbasi","doi":"10.1016/j.ijidoh.2025.100058","DOIUrl":"10.1016/j.ijidoh.2025.100058","url":null,"abstract":"<div><div>The global expansion of <em>Aedes</em> mosquitoes, particularly, <em>Aedes aegypti</em> and <em>Aedes albopictus</em>, has significantly contributed to the transboundary spread of arboviral diseases such as dengue, Zika, chikungunya, and yellow fever. This systematic review, conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, aimed to investigate the ecological, environmental, and socioeconomic factors driving the proliferation of <em>Aedes</em> mosquitoes and their role in arboviral disease transmission. Relevant studies were identified through comprehensive searches in PubMed, Scopus, Web of Science, and Embase, with a focus on the geographic distribution, behavioral characteristics, and transmission dynamics of <em>Aedes</em> species. This research has been registered in the International Prospective Register of Systematic Review (PROSPERO), with the code CRD42021231605. The results revealed that climate change, globalization, urbanization, and human mobility are key drivers of the global spread of <em>Aedes</em> mosquitoes. Rising temperatures and altered precipitation patterns have facilitated their expansion into temperate regions, whereas urbanization has created ideal breeding environments. In addition, globalization and international travel have accelerated the introduction of arboviruses into non-endemic areas. This review highlights that effective vector control necessitates climate-resilient strategies, stronger international collaboration, and innovative interventions, including Wolbachia-based and genetically modified mosquitoes. Addressing the complex challenges posed by <em>Aedes</em>-borne arboviruses is critical for mitigating their global health impact.</div></div>","PeriodicalId":100655,"journal":{"name":"IJID One Health","volume":"6 ","pages":"Article 100058"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preparedness for One Health Surveillance System: A qualitative in-depth exploration in Gujarat, India 一个卫生监测系统的准备：在印度古吉拉特邦进行质的深入探索

IJID One Health Pub Date : 2025-02-07 DOI: 10.1016/j.ijidoh.2025.100055

Sandul Yasobant , Ravina Tadvi , Deepak B. Saxena

{"title":"Preparedness for One Health Surveillance System: A qualitative in-depth exploration in Gujarat, India","authors":"Sandul Yasobant , Ravina Tadvi , Deepak B. Saxena","doi":"10.1016/j.ijidoh.2025.100055","DOIUrl":"10.1016/j.ijidoh.2025.100055","url":null,"abstract":"<div><h3>Background</h3><div>The One Health approach, emphasizing collaboration across human, animal, and environmental health sectors, is recognized as crucial for mitigating zoonotic disease risks. Despite existing human and animal health surveillance systems, operational integration and effective coordination remain challenges. However, the potential for enhancing integrated disease control efforts is promising. Establishing inter-sectoral collaboration is essential for generating early warning signals, conducting joint investigations, and mounting coordinated responses to outbreaks.</div></div><div><h3>Objective</h3><div>This study aimed to investigate sectoral collaborations within Gujarat's (Western Indian state) disease surveillance system, shedding light on the challenges and opportunities for enhancing integrated disease control efforts from the One Health perspective.</div></div><div><h3>Methods</h3><div>This qualitative study, conducted in Gujarat, India, from May 2023 to June 2024, employed in-depth interviews as the primary data collection method. The study focused on exploring the unique relationships between human and animal disease surveillance systems and their stakeholders’ with each other at both the state and district levels, providing a comprehensive understanding of the sectoral collaborations.</div></div><div><h3>Result</h3><div>The study identified huge opportunities to translate the surveillance system towards One Health Surveillance systems by strengthening intersectoral data sharing and reporting portals, as well as integration between health and animal sectors for early warning systems.</div></div><div><h3>Conclusion</h3><div>By enhancing coordination, investing in resources, and fostering partnerships, the state can build robust mechanisms for timely identification and response to emerging health threats, ultimately safeguarding the well-being of its population from One Health perspective.</div></div>","PeriodicalId":100655,"journal":{"name":"IJID One Health","volume":"6 ","pages":"Article 100055"},"PeriodicalIF":0.0,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143386388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Epidemiology of human contacts of equine Hendra virus infection in northern New South Wales, Australia, 2006–2023 2006-2023年澳大利亚新南威尔士州北部马亨德拉病毒感染人类接触者的流行病学

IJID One Health Pub Date : 2025-02-05 DOI: 10.1016/j.ijidoh.2025.100054

Keeley Allen , Genevieve K. O’Neill , Robin Auld , Joanne Taylor , David N. Durrheim

{"title":"Epidemiology of human contacts of equine Hendra virus infection in northern New South Wales, Australia, 2006–2023","authors":"Keeley Allen , Genevieve K. O’Neill , Robin Auld , Joanne Taylor , David N. Durrheim","doi":"10.1016/j.ijidoh.2025.100054","DOIUrl":"10.1016/j.ijidoh.2025.100054","url":null,"abstract":"<div><h3>Objectives</h3><div>Hendra virus is an important zoonotic pathogen in Australia, with widespread presence in flying fox reservoirs and serious health consequences for horses and humans. This study describes the epidemiology of all human contacts of confirmed Hendra virus cases in New South Wales (NSW) to inform future public health responses.</div></div><div><h3>Methods</h3><div>A cross-sectional study was conducted of all known human contacts in three Local Health Districts in NSW from 2006 to 2023, representing all equine Hendra virus events in NSW to date. Data was extracted from the NSW Notifiable Conditions Information Management System.</div></div><div><h3>Results</h3><div>A total of 26 equine Hendra events occurred, with 134 human contacts. NSW equine Hendra virus events and associated human contacts predominantly occurred in winter and spring, in part, driven by seasonal variation in flying fox ecology. Human contacts most often reported being owners of the horse or owner’s family members, including the majority (n = 15 of 18, 83 %) of higher-risk contacts. Higher-risk contacts often did not use personal protective equipment (n = 15 of 18, 83 %). No human contacts developed Hendra virus infection during the study period.</div></div><div><h3>Conclusions</h3><div>Higher-risk human contacts often occurred with limited or no use of personal protective equipment, often in the context of stress and grief for the ill or dead horse, and contrary to biosecurity advice. This study highlights the importance of a One Health approach to understand Hendra virus spillover infection risks in horses and humans and design appropriate, effective prevention measures that address these human behaviors.</div></div>","PeriodicalId":100655,"journal":{"name":"IJID One Health","volume":"6 ","pages":"Article 100054"},"PeriodicalIF":0.0,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143428029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acute bartonellosis caused by Bartonella quintana in a sheep farmer – An unidentified mode of transmission for ‘trench fever’ 一名养羊农民由金塔纳巴尔通体引起的急性巴尔通体病——一种尚未确定的“沟热”传播模式

IJID One Health Pub Date : 2025-01-22 DOI: 10.1016/j.ijidoh.2025.100053

R. O’Regan , D.M. McGee , J.L. Lambert

引用次数: 0

High prevalence and non-suppression of HIV/AIDS in the East and Central African region heightens risk of severe outcomes for Clade I monkeypox virus infection, and may be a driver for subsequent adaptation 在东非和中非地区，艾滋病毒/艾滋病的高流行率和未得到抑制增加了I支猴痘病毒感染严重后果的风险，并可能成为随后适应的驱动因素

IJID One Health Pub Date : 2024-12-02 DOI: 10.1016/j.ijidoh.2024.100050

Henry Kyobe Bosa , Winters Muttamba , Barnabas Bakamutumaho , Edson Rwagasore , John Runumu , Mudarshiru Bbuye , Wilber Sabiiti , Abdul Nyanzi , Jacqueline Weyer , Joel Francis , Ntuli A. Kapologwe , Patrick Katoto , Bruce Kirenga , Misaki Wayengera

{"title":"High prevalence and non-suppression of HIV/AIDS in the East and Central African region heightens risk of severe outcomes for Clade I monkeypox virus infection, and may be a driver for subsequent adaptation","authors":"Henry Kyobe Bosa , Winters Muttamba , Barnabas Bakamutumaho , Edson Rwagasore , John Runumu , Mudarshiru Bbuye , Wilber Sabiiti , Abdul Nyanzi , Jacqueline Weyer , Joel Francis , Ntuli A. Kapologwe , Patrick Katoto , Bruce Kirenga , Misaki Wayengera","doi":"10.1016/j.ijidoh.2024.100050","DOIUrl":"10.1016/j.ijidoh.2024.100050","url":null,"abstract":"<div><div>In September 2023, a re-emergence of mpox was noted in the province of South Kivu, in DR Congo. So far, active transmission has been reported in 23 of the 26 provinces. Despite localisation within DRC, there are emerging concerns about possibility of cross-border transmission. In this perspective, we highlight the threat posed to HIV positive patients, particularly those with unsuppressed viral loads. We make several prepositions as part of the preparedness and response plans in the countries in the East and Central Africa region. The six prepositions include: 1) operationalize the Joint Africa Task Force for mpox consistent with Kinshasa declaration on mpox, 2) increased surveillance, 3) deployment of point of care diagnostics, 4) targeted reactive vaccination and enhanced antiretroviral therapy of HIV positive patients in areas of active transmission, 5) community engagement, 6) foster capacity building of national rapid response teams in East and Central Africa in mpox care and management through collaboration with DRC counterparts.</div></div>","PeriodicalId":100655,"journal":{"name":"IJID One Health","volume":"6 ","pages":"Article 100050"},"PeriodicalIF":0.0,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143105318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antimicrobial resistance (AMR): ISID’s global efforts to bring light to the silent pandemic 抗菌素耐药性（AMR）：国际抗微生物药物研究所在全球努力揭示这一无声的流行病

IJID One Health Pub Date : 2024-12-01 DOI: 10.1016/j.ijidoh.2024.100049

Mohamed M. Sirdar, Jarod Hanson, Julia Maxwell, Ghassan M. Matar, Tin Tin Myaing, Alison Holmes

引用次数: 0