IJID One Health最新文献

{"title":"Comparative epidemiological analysis of the 2023 and 2025 Marburg virus disease outbreaks in Kagera Region, Tanzania","authors":"Sima Rugarabamu ,&nbsp;Baraka L. Ngingo ,&nbsp;Elison E. Kemibala ,&nbsp;Gaspary Mwanyika","doi":"10.1016/j.ijidoh.2025.100094","DOIUrl":"10.1016/j.ijidoh.2025.100094","url":null,"abstract":"<div><h3>Objectives</h3><div>Marburg virus disease (MVD) is a severe zoonotic hemorrhagic fever with high case fatality rates (CFR). Tanzania's Kagera Region experienced MVD outbreaks in 2023 and 2025, offering critical insights into evolving epidemiological trends and the effectiveness of response strategies. This study compares these outbreaks to inform future preparedness.</div></div><div><h3>Methods</h3><div>We conducted a retrospective analysis of official situation reports from the Tanzanian Ministry of Health, the World Health Organization (WHO), and other health authorities. Data on sociodemographic, CFR, transmission dynamics, response metrics (alerts, samples, contacts), and response timelines were analyzed using descriptive statistics, chi-square, and <em>t</em> tests. The time-varying reproduction number (Re) was estimated using the EpiEstim R package.</div></div><div><h3>Results</h3><div>The 2025 outbreak had a significantly higher CFR (100 %) compared to 2023 (66.7 %) (<em>P</em> &lt;0.05). Demographic shifts included a decrease in median age from 35 to 30 years and a reversal in sex distribution, with women more affected in 2025 (70 %) vs men in 2023 (66.7 %) (<em>P</em> = 0.03). The outbreak epicenter shifted from Bukoba to Biharamulo district. While the scale of response increased dramatically in 2025 (alerts: 131 to 1218; samples tested: 78 to 202), the initial response was delayed, with a longer interval from symptom onset to outbreak declaration (37 days in 2025 vs 10 days in 2023) and initial diagnostic confusion. Mean Re was &lt;1 throughout the 2023 outbreak but exceeded 1 mid-epidemic in 2025.</div></div><div><h3>Conclusions</h3><div>The 2025 outbreak was characterized by increased lethality and distinct demographic shifts. The response demonstrated a significant scale-up in surveillance and international coordination. However, critical challenges in early detection, diagnostic confirmation, and the efficiency of converting alerts into traced contacts highlight the need for a balanced strategy that couples technological innovation with fundamental strengthening of health system core functions.</div></div>","PeriodicalId":100655,"journal":{"name":"IJID One Health","volume":"10 ","pages":"Article 100094"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145799642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"One Health and antimicrobial resistance in Somalia: policy insights from Centennial Vision 2060","authors":"Shafie Abdulkadir Hassan ,&nbsp;Nur Rashid Ahmed ,&nbsp;Abdifetah Ibrahim Omar ,&nbsp;Kassim Abdi Jimale","doi":"10.1016/j.ijidoh.2026.100111","DOIUrl":"10.1016/j.ijidoh.2026.100111","url":null,"abstract":"<div><h3>Objectives</h3><div>This study aimed to assess the extent to which Somalia’s Centennial Vision 2060 (CV2060) provides a strategic framework for addressing antimicrobial resistance (AMR) and advancing a One Health approach. Unlike previous epidemiologic assessments, this study uniquely positions AMR containment as a function of state-building, focusing on governance, human capital, and health system integration.</div></div><div><h3>Methods</h3><div>A qualitative document analysis was conducted on the official English-language version of CV2060, treating the policy as a social fact. Using the Walt and Gilson policy triangle framework, the analysis examined the document across four dimensions: context, content, actors, and process. To ensure methodologic rigor, the text was independently coded by two reviewers against three predefined domains, with discrepancies resolved through consensus. Data were managed using a matrix analysis approach.</div></div><div><h3>Results</h3><div>Analysis revealed four inter-related themes relevant to AMR: (1) strengthening health system governance and regulatory capacity, (2) human capital development in health and veterinary sectors, (3) integrated One Health vision, and (4) digital transformation and data systems. Specific policy levers identified include the potential for digital import tracking to monitor antibiotic consumption and the use of judicial reform to criminalize unlicensed pharmaceutical sales. Although AMR is not explicitly mentioned, CV2060 provides foundational mechanisms that can support AMR prevention.</div></div><div><h3>Conclusions</h3><div>CV2060 establishes a scientifically and operationally viable framework to support AMR mitigation and One Health integration in Somalia. To operationalize this, the study recommends establishing a cross-sectoral AMR steering committee within the CV2060 implementation unit and explicitly integrating antimicrobial stewardship competencies into the proposed national curriculum.</div></div>","PeriodicalId":100655,"journal":{"name":"IJID One Health","volume":"10 ","pages":"Article 100111"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147396622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Infectious disease eradication—the pinnacle of public health achievement","authors":"David N. Durrheim ,&nbsp;Jon K. Andrus ,&nbsp;Shahina Tabassum","doi":"10.1016/j.ijidoh.2026.100107","DOIUrl":"10.1016/j.ijidoh.2026.100107","url":null,"abstract":"","PeriodicalId":100655,"journal":{"name":"IJID One Health","volume":"10 ","pages":"Article 100107"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147397158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral rabies vaccine baiting and targeted removal strategies for dog-mediated rabies outbreak control: A modelling framework for outbreak management","authors":"Tong Guan ,&nbsp;Rayson Bock Hing Lim ,&nbsp;Shihui Jin ,&nbsp;Kelvin Ho ,&nbsp;Malcolm Soh ,&nbsp;Alwyn Tan ,&nbsp;Wendy Sng ,&nbsp;A. Janhavi ,&nbsp;Gregory Gan ,&nbsp;Pei Ma ,&nbsp;Nigel Lim ,&nbsp;Jue Tao Lim ,&nbsp;Tze-Hoong Chua ,&nbsp;Borame L. Dickens","doi":"10.1016/j.ijidoh.2026.100109","DOIUrl":"10.1016/j.ijidoh.2026.100109","url":null,"abstract":"<div><h3>Background</h3><div>Support for ongoing regional rabies elimination efforts in dogs and reducing cross border transmission is vital to prevent outbreaks. We explore the effectiveness of two control interventions, oral rabies vaccination (ORV) and targeted ring removal (TRR).</div></div><div><h3>Methods</h3><div>A spatio-temporal compartmental microsimulation model of 2200 free-roaming dogs (FRDs) was fitted to surveillance data with multiple rabies importation events modelled. Based on estimated dog biting rates, seven intervention strategies were explored to assess transmission risk reduction.</div></div><div><h3>Results</h3><div>In the absence of intervention, median human infections over 50 months were 0 (interquartile range: 0–8), 1 (0–11) and 16 (5–29) for one-time, once-per-year, and once-per-month importation events, with 23.5 %, 63.1 %, and 99.97 % of simulations estimating at least one human case. For one-time and annual importation, 90 % dog population TRR reduced this to 5.0 % and 23.5 %. Under monthly importation, both TRR and ORV did not substantially reduce the number of simulations without infection but did reduce the number of infections down to 4 (0–12) and 3 (0–8).</div></div><div><h3>Conclusions</h3><div>ORV can be successfully utilised for dog-mediated rabies outbreak control in elimination settings for intermediate importation rates, while high TRR rates are required for an equivalent impact.</div></div>","PeriodicalId":100655,"journal":{"name":"IJID One Health","volume":"10 ","pages":"Article 100109"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147397157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reviewer Thank You List, 2025","authors":"","doi":"10.1016/S2949-9151(26)00016-8","DOIUrl":"10.1016/S2949-9151(26)00016-8","url":null,"abstract":"","PeriodicalId":100655,"journal":{"name":"IJID One Health","volume":"10 ","pages":"Article 100118"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147538339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Q fever vaccines – a Veterinary Perspective","authors":"Benjamin U. Bauer ,&nbsp;Martin Ganter ,&nbsp;Jasmin Fertey ,&nbsp;Gustavo R. Makert ,&nbsp;Katja Mertens-Scholz ,&nbsp;Michael R. Knittler","doi":"10.1016/j.ijidoh.2025.100099","DOIUrl":"10.1016/j.ijidoh.2025.100099","url":null,"abstract":"","PeriodicalId":100655,"journal":{"name":"IJID One Health","volume":"10 ","pages":"Article 100099"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147538342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contrasting Q fever perception among European large animal veterinary practitioners, 2024","authors":"Raphaël Guatteo ,&nbsp;George Valiakos ,&nbsp;Vincent Dedet ,&nbsp;Alda Natale ,&nbsp;Ángel Gómez Martín ,&nbsp;Daniel Cifo Arcos ,&nbsp;Jonathan Statham ,&nbsp;Laurent Delooz ,&nbsp;Piet Vellema ,&nbsp;Sławomir Koźmiński ,&nbsp;Thomas Wittek","doi":"10.1016/j.ijidoh.2025.100097","DOIUrl":"10.1016/j.ijidoh.2025.100097","url":null,"abstract":"","PeriodicalId":100655,"journal":{"name":"IJID One Health","volume":"10 ","pages":"Article 100097"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147538764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of risk factors associated with Plasmodium knowlesi infection in Sarawak, Malaysia","authors":"Anfal Abdelgadir ,&nbsp;Jane K. Fieldhouse ,&nbsp;Teck-Hock Toh ,&nbsp;Emily S. Bailey ,&nbsp;Jakie Ting ,&nbsp;Tiing-Tiing Chua ,&nbsp;Kamilah Dahian ,&nbsp;Jeffrey Soon-Yit Lee ,&nbsp;King-Ching Hii ,&nbsp;Awang Emir Naim ,&nbsp;Karen Mei Er Lim ,&nbsp;Pravind A.L. Narayanan ,&nbsp;Eng-Seng Tiew ,&nbsp;Mohd Raili Suhaili ,&nbsp;Gregory C. Gray","doi":"10.1016/j.ijidoh.2025.100102","DOIUrl":"10.1016/j.ijidoh.2025.100102","url":null,"abstract":"<div><h3>Objectives</h3><div>Human cases of <em>Plasmodium knowlesi</em> malaria have significantly increased in recent years, especially in Malaysia. Understanding the risk factors associated with <em>P. knowlesi</em> infections is crucial for improving surveillance and developing effective control strategies. This study sought to identify key risk factors for infection with <em>P. knowlesi</em> in East Malaysia.</div></div><div><h3>Methods</h3><div>From June to August 2019, patients aged ≥7 years with suspected malaria were enrolled at Sibu, Kapit, and Sarikei Hospitals in Sarawak, Malaysia. Blood samples were screened using microscopy and nested polymerase chain reaction to confirm <em>P. knowlesi</em> infection. Demographics, occupation, work environment, medical history, and exposure to animals data were collected through structured questionnaires.</div></div><div><h3>Results</h3><div>Of the 115 patients, 52 (45.2 %) tested positive for <em>P. knowlesi</em>. Patients from Kapit Hospital, a rural area, had twice the odds of testing positive compared to those from urban hospitals. Male gender and living near vegetation, such as plantations, forests, or rice paddies, were also significantly associated with infection.</div></div><div><h3>Conclusions</h3><div>These findings document a high prevalence of <em>P. knowlesi</em> in Sarawak and highlight the need for One Health approaches to control this zoonotic disease, focusing on education, mosquito control, and reducing contact with non-human primates.</div></div>","PeriodicalId":100655,"journal":{"name":"IJID One Health","volume":"10 ","pages":"Article 100102"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145978276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Toxocariasis as an emerging public health challenge: an update on One Health future and challenges","authors":"Soheil Sadr,&nbsp;Hassan Borji","doi":"10.1016/j.ijidoh.2026.100105","DOIUrl":"10.1016/j.ijidoh.2026.100105","url":null,"abstract":"<div><div>Toxocariasis is an important zoonotic disease caused by the migration of larvae of nematode parasites of the genus <em>Toxocara</em>, especially <em>Toxocara canis</em> and <em>Toxocara cati</em>, in the human body. Toxocariasis is associated with global spread and multiple clinical complications, including visceral, ocular, and neurological larval migratory syndrome, and has, therefore, been considered a major global health concern. From the perspective of epidemiology, pathophysiology, diagnosis, treatment, prevention, and challenges associated with toxocariasis, this review will provide a comprehensive overview of toxocariasis, highlighting how One Health is essential to promoting effective and sustainable community-based control strategies. As a result of the parasite eggs’ high resistance to the environment in deprived communities and communities in which stray dogs and cats are present, toxocariasis is primarily a disease in children. According to previous studies, significant levels of soil contamination have been reported in various public areas, including parks, schools, and public restrooms, which indicates a potential danger to public health. Through the integration of One Health concepts, it is possible to evaluate the factors that influence the parasite transmission cycle at the level of the human society, livestock population, and natural habitat on an integrated basis, so that interventions, such as vaccinations for domestic animals, epidemiological surveys, and multi-level education can be carried out in an integrated fashion. Despite recent scientific advances, several challenges remain, including the lack of accurate epidemiological data in many regions of the world, difficulties associated with a definitive diagnosis, parasite resistance in the environment, limited attention to toxocariasis as a neglected disease, and insufficient resources allocated to its control.</div></div>","PeriodicalId":100655,"journal":{"name":"IJID One Health","volume":"10 ","pages":"Article 100105"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146037810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing knowledge, attitudes, and preventive practices of smallholder livestock farmers toward antimicrobial use, resistance, and sources in Bangladesh","authors":"Md. Abdur Nur Sakib ,&nbsp;Probir Mitro ,&nbsp;Fahmida Yesmin Oishee ,&nbsp;Prity Ranjan Talukdar ,&nbsp;Zabed Mazumder ,&nbsp;Raisa Islam ,&nbsp;Sumayae Binta Khaiat ,&nbsp;Md. Zahid Hossain ,&nbsp;Md. Mukter Hossain","doi":"10.1016/j.ijidoh.2025.100101","DOIUrl":"10.1016/j.ijidoh.2025.100101","url":null,"abstract":"<div><h3>Objectives</h3><div>This study aimed to assess knowledge, attitudes, and preventive practices (KAP) among smallholder livestock farmers toward antimicrobial use (AMU) and antimicrobial resistance (AMR).</div></div><div><h3>Methods</h3><div>A cross-sectional survey was conducted using structured, closed-ended questionnaires through face-to-face interviews. A total 390 farmers were randomly selected from five purposively chosen districts. Descriptive statistics, Multivariate logistic regression, and Spearman’s rank correlation analyses were performed.</div></div><div><h3>Results</h3><div>The survey revealed significant gaps in knowledge and practices related to AMU and AMR, with only 17 % of respondents demonstrating adequate knowledge and 31 % adhering to appropriate practices, despite a high proportion (88 %) expressing positive attitude. Multivariable analysis indicated that farmers who had training on AMU and AMR were more likely better knowledge (adjusted odd ratio [AOR] = 6.00; 95 % confidence interval [CI]: 2.99–12.30), attitude (AOR = 1.81; 95 % CI: 0.57–7.18), and practices (AOR = 2.46; 95 % CI: 1.27–4.80) compared to those without training. Although 44 % farmers reported obtaining antimicrobials through registered medical practitioners, whereas 19 % adhered to the recommended guidelines for AMU.</div></div><div><h3>Conclusions</h3><div>The findings of this study will inform targeted educational and training interventions for farmers, aiming to curb the indiscriminate and inappropriate use of antimicrobials, thereby contributing to a reduction in the risk of AMR development.</div></div>","PeriodicalId":100655,"journal":{"name":"IJID One Health","volume":"10 ","pages":"Article 100101"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145927783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}