{"title":"Maturation of medial temporal lobe response and connectivity during memory encoding","authors":"V. Menon , J.M. Boyett-Anderson , A.L. Reiss","doi":"10.1016/j.cogbrainres.2005.07.007","DOIUrl":"10.1016/j.cogbrainres.2005.07.007","url":null,"abstract":"<div><p><span>The medial temporal lobe<span> (MTL) plays an important role in memory encoding. The development and maturation of MTL and other brain regions involved in memory encoding are, however, poorly understood. We used functional magnetic resonance imaging to examine activation and effective connectivity of the MTL in children and adolescents during encoding of outdoor visual scenes. Here, we show that MTL response decreases with age whereas its connectivity with the left dorsolateral prefrontal cortex (PFC) increases with age. Our findings provide evidence for dissociable maturation of local and distributed memory encoding processes involving the MTL and furthermore suggest that increased functional interactions between the MTL and the </span></span>PFC may underlie the development of more effective memory encoding strategies.</p></div>","PeriodicalId":100287,"journal":{"name":"Cognitive Brain Research","volume":"25 1","pages":"Pages 379-385"},"PeriodicalIF":0.0,"publicationDate":"2005-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.cogbrainres.2005.07.007","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25268987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kerrie E. Elston-Güttler, Thomas C. Gunter, Sonja A. Kotz
{"title":"Zooming into L2: Global language context and adjustment affect processing of interlingual homographs in sentences","authors":"Kerrie E. Elston-Güttler, Thomas C. Gunter, Sonja A. Kotz","doi":"10.1016/j.cogbrainres.2005.04.007","DOIUrl":"10.1016/j.cogbrainres.2005.04.007","url":null,"abstract":"<div><p><span>In a semantic priming study, we investigated the processing of German–English homographs such as </span><em>gift</em> (German = “poison”, English = “present”) in sentence contexts using a joint reaction time (RT)/event-related brain potential (ERP) measure. Native German speakers with intermediate or advanced knowledge of English (<em>N</em> = 48) performed an all-L2 (English) experiment where sentences such as “The woman gave her friend an expensive <em>gift</em>” (control prime: <em>item</em>) were presented, followed by targets (i.e., <em>boss</em><span>) for lexical decision. To test the role of global task effects during sentence processing, we presented half the participants (</span><em>N</em> = 24) with a 20-min silent film narrated in German and half (<em>N</em> = 24) with the film in English before the experiment. To address the development of task effects over time, we analyzed the first and second blocks of the experiment. The results showed a significant interaction between semantic priming, movie version, and block in both the RTs and ERPs: there was significant semantic priming in the RTs and modulations in the N200 and N400 components only for participants who viewed the German movie, and only during the first block. Results suggest that in an all-L2 sentence task with L2 pre-task priming (English film), decision thresholds are raised high enough to eliminate measurable influence of the L1 on the L2. Despite identical material, participants who viewed the German film had to adjust, or <em>zoom in</em>, to the all-L2 task. Implications of this zooming in process in are discussed in terms of the recent Bilingual Interactive Activation (BIA+) model of bilingual word recognition [T. Dijkstra, W.J.B. Van Heuven, The architecture of the bilingual word recognition system: from identification to decision, Bilingualism: Lang. Cogn. 5 (2002) 175–197].</p></div>","PeriodicalId":100287,"journal":{"name":"Cognitive Brain Research","volume":"25 1","pages":"Pages 57-70"},"PeriodicalIF":0.0,"publicationDate":"2005-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.cogbrainres.2005.04.007","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25292591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aljoscha C. Neubauer, Roland H. Grabner, Andreas Fink, Christa Neuper
{"title":"Intelligence and neural efficiency: Further evidence of the influence of task content and sex on the brain–IQ relationship","authors":"Aljoscha C. Neubauer, Roland H. Grabner, Andreas Fink, Christa Neuper","doi":"10.1016/j.cogbrainres.2005.05.011","DOIUrl":"10.1016/j.cogbrainres.2005.05.011","url":null,"abstract":"<div><p>In the field of physiological study of human intelligence, strong evidence of a more efficient operation (i.e., less activation) of the brain in brighter individuals (the <em>neural efficiency</em> hypothesis) can be found. Most studies in this field have used single, homogeneous tasks and have not examined sex differences. In analyzing the extent of Event-related Desynchronization (ERD) in the EEG during the performance of a verbal and a visuo-spatial task, we recently found that males and females display <em>neural efficiency</em> primarily in the domain where they usually perform better (i.e., verbal in females and spatial in males; cf. A.C. Neubauer, A. Fink, D.G. Schrausser, Intelligence and neural efficiency: the influence of task content and sex on brain–IQ relationship. Intelligence, 30 (2002) 515–536). However, this interpretation was complicated by differences in the complexity of the two tasks. By using a verbal (semantic) and a spatial (rotation) task of comparable complexity in this research, we sought to replicate and extend our earlier findings by additionally considering the individual differences in intelligence structure and the topographical distribution over the cortex. Findings were similar to the previous study: Females (<em>n</em> = 35) display <em>neural efficiency</em> (i.e., less brain activation in brighter individuals) primarily during the verbal task, males (<em>n</em> = 31) in the spatial task. However, the strength of this brain activation–IQ relationship varies with the intelligence factor: In males, the highest correlations were observed for spatial IQ, in females for verbal IQ. Furthermore, the sexes displayed topographical differences of <em>neural efficiency</em> patterns.</p></div>","PeriodicalId":100287,"journal":{"name":"Cognitive Brain Research","volume":"25 1","pages":"Pages 217-225"},"PeriodicalIF":0.0,"publicationDate":"2005-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.cogbrainres.2005.05.011","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25196982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anthony J. Angwin , Helen J. Chenery , David A. Copland , Bruce E. Murdoch , Peter A. Silburn
{"title":"Summation of semantic priming and complex sentence comprehension in Parkinson's disease","authors":"Anthony J. Angwin , Helen J. Chenery , David A. Copland , Bruce E. Murdoch , Peter A. Silburn","doi":"10.1016/j.cogbrainres.2005.04.008","DOIUrl":"10.1016/j.cogbrainres.2005.04.008","url":null,"abstract":"<div><p>Research has suggested that the integrity of semantic processing<span><span> may be compromised in Parkinson's disease (PD), which may account for difficulties in complex sentence comprehension. In order to investigate the time course and integrity of semantic activation in PD, 20 patients with PD and 23 healthy controls performed a </span>lexical decision<span> task based on the multi-priming paradigm. Semantic priming effects were measured across stimulus onset asynchronies of 250 ms, 600 ms, and 1200 ms. Further, PD participants performed an auditory comprehension task. The results revealed significantly different patterns of semantic priming for the PD group at the 250-ms and 1200-ms SOAs. In addition, a delayed time course of semantic activation was evident for PD patients with poor comprehension of complex sentences. These results provide further support to suggest that both automatic and controlled aspects of semantic activation may be compromised in PD. Furthermore, the results also suggest that some sentence comprehension deficits in PD may be related to a reduction in information processing speed.</span></span></p></div>","PeriodicalId":100287,"journal":{"name":"Cognitive Brain Research","volume":"25 1","pages":"Pages 78-89"},"PeriodicalIF":0.0,"publicationDate":"2005-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.cogbrainres.2005.04.008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25111121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maarten A.S. Boksem, Theo F. Meijman, Monicque M. Lorist
{"title":"Effects of mental fatigue on attention: An ERP study","authors":"Maarten A.S. Boksem, Theo F. Meijman, Monicque M. Lorist","doi":"10.1016/j.cogbrainres.2005.04.011","DOIUrl":"10.1016/j.cogbrainres.2005.04.011","url":null,"abstract":"<div><p>The effects of mental fatigue on attention were assessed. Subjects performed a visual attention task for 3 h without rest. Subjective levels of fatigue, performance measures and EEG were recorded. Subjective fatigue ratings, as well as theta and lower-alpha EEG band power increased, suggesting that the 3 h of task performance resulted in an increase in fatigue. Reaction times, misses and false alarms increased with time on task, indicating decreased performance efficiency in fatigued subjects. Subjects were unable to inhibit automatic shifting of attention to irrelevant stimuli, reflected by a larger negativity in the N1 latency range for irrelevant, compared to relevant stimuli. This difference in negativity was unaffected by time on task. However, N1 and N2b amplitude did change with time on task: N1 amplitude decreased, and the difference in N2b amplitude between relevant and irrelevant stimuli (larger N2b amplitude evoked by relevant stimuli) decreased with time on task. The results indicate a dissociation in the effects of mental fatigue on goal-directed (top–down) and stimulus-driven (bottom–up) attention: mental fatigue results in a reduction in goal-directed attention, leaving subjects performing in a more stimulus-driven fashion.</p></div>","PeriodicalId":100287,"journal":{"name":"Cognitive Brain Research","volume":"25 1","pages":"Pages 107-116"},"PeriodicalIF":0.0,"publicationDate":"2005-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.cogbrainres.2005.04.011","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40928614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Durk Talsma , Heleen A. Slagter , Sander Nieuwenhuis , Jasper Hage , Albert Kok
{"title":"The orienting of visuospatial attention: An event-related brain potential study","authors":"Durk Talsma , Heleen A. Slagter , Sander Nieuwenhuis , Jasper Hage , Albert Kok","doi":"10.1016/j.cogbrainres.2005.04.013","DOIUrl":"10.1016/j.cogbrainres.2005.04.013","url":null,"abstract":"<div><p>This study investigated the electrophysiological correlates of shifting, maintaining, and relaxing the focus of attention, using a symbolic cuing task. Cues and imperative stimuli were presented in rapid succession, and the ADJAR procedure was used to remove the contribution of event-related potential (ERP) activity associated with the imperative stimulus from the cue-related ERP waveforms. Initial analyses, comparing left and right attention-directing cues, replicated previous findings of early directing attention negativity (EDAN) and anterior directing attention negativity (ADAN) effects. To isolate ERP activity that is common to leftward and rightward attention shifts, the combined ERP activity elicited by attention-directing cues was compared to the ERP activity elicited by non-informative cues. This analysis revealed a strong and broadly distributed early positivity followed by a sustained central negativity, possibly reflecting the controlled orienting and subsequent maintenance of attentional focus. Finally, imperative stimuli preceded by non-informative cues were characterized by an enhanced posterior P2 effect, with a scalp distribution indicative of generators in visual areas. This result suggests a relatively late (re)activation in visual areas associated with the processing of stimuli that had not been cued in advance.</p></div>","PeriodicalId":100287,"journal":{"name":"Cognitive Brain Research","volume":"25 1","pages":"Pages 117-129"},"PeriodicalIF":0.0,"publicationDate":"2005-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.cogbrainres.2005.04.013","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40939022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Charles Suaudeau , Jean-Claude do-Rego , Jean Costentin
{"title":"Modifications in avoidance reactions of mice, on a second exposure to the hot plate, resist to various amnesia-inducing treatments","authors":"Charles Suaudeau , Jean-Claude do-Rego , Jean Costentin","doi":"10.1016/j.cogbrainres.2005.06.007","DOIUrl":"10.1016/j.cogbrainres.2005.06.007","url":null,"abstract":"<div><p>The avoidance responses of mice exposed to the hot plate (55 °C) were found to be modified when tested a second time. In fact, when forepaws licking was no longer observed, the rearing was clearly anticipated (7 s instead of 15 s) as well as jumping (24 s instead of 55 s). These modifications of avoidance strategies as well as their latencies were still observed even 24 days after the first exposure. Avoidance responses were prevented by morphine or haloperidol<span><span> injected prior to the first exposure, but not with scopolamine or </span>diazepam. These modifications were not affected in mice injected with morphine or submitted to either a supramaximal electroshock or to ether anesthesia delivered immediately after the first hot plate exposure. Among the various known types of memory, these modifications could be linked to procedural memory.</span></p></div>","PeriodicalId":100287,"journal":{"name":"Cognitive Brain Research","volume":"25 1","pages":"Pages 339-347"},"PeriodicalIF":0.0,"publicationDate":"2005-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.cogbrainres.2005.06.007","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24927725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter processing interferes with inhibition of return: Evidence for cortical involvement","authors":"Ben Bowles, Susanne Ferber, Jay Pratt","doi":"10.1016/j.cogbrainres.2005.04.005","DOIUrl":"10.1016/j.cogbrainres.2005.04.005","url":null,"abstract":"<div><p><span>Inhibition of return (IOR) refers to the finding that, when the time lag between a cue and a target is prolonged, the reaction to the target, when it eventually appears, is actually slower than with no cue. This phenomenon is thought to make visual search more efficient, and it is subserved by the left inferior parietal cortex and the </span>supramarginal gyrus bilaterally. Interestingly, the very same brain structures are also involved in letter processing. Accordingly, we asked whether the two mental processes interfere with each other when simultaneously probed. The first experiment used a typical IOR procedure, but the cue/target placeholders were either simple geometric shapes or English letters. The results show that, although IOR is approximately the same across visual fields when shape placeholders are used, it is significantly lessened in the right visual field when letters are used as cue and target placeholders. To examine if this finding was due to potential spatial frequency differences between the placeholders, a second experiment using shapes and Japanese letters was conducted, and no differences in IOR were found. The supramarginal gyrus appears to be the most likely locus for the letter-IOR interference effect because it is active bilaterally in IOR, but only in the left hemisphere during letter processing. These findings provide support for the notion that IOR is not simply due to subcortical processes but also involves processing from cortical structures.</p></div>","PeriodicalId":100287,"journal":{"name":"Cognitive Brain Research","volume":"25 1","pages":"Pages 1-7"},"PeriodicalIF":0.0,"publicationDate":"2005-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.cogbrainres.2005.04.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25111120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Paul A. Howard-Jones , Sarah-Jayne Blakemore , Elspeth A. Samuel , Ian R. Summers , Guy Claxton
{"title":"Semantic divergence and creative story generation: An fMRI investigation","authors":"Paul A. Howard-Jones , Sarah-Jayne Blakemore , Elspeth A. Samuel , Ian R. Summers , Guy Claxton","doi":"10.1016/j.cogbrainres.2005.05.013","DOIUrl":"10.1016/j.cogbrainres.2005.05.013","url":null,"abstract":"<div><p>The aim of this fMRI investigation was to identify those areas of the brain associated with approaching a story generation task creatively and to investigate the effects upon these correlates of incorporating a set of words that were unrelated to each other—a strategy considered to encourage semantic divergence. Preliminary experiments were undertaken to investigate the possible confounding effects of the scanner environment upon creativity and to reveal the effects of creative effort and word relatedness upon the creativity of those who would be participating in the fMRI scan. In the final part of the investigation, a factorial fMRI design was used to elucidate brain regions involved in increased creative effort and also the effect upon activity in these regions when participants incorporated words that bore little semantic relationship with each other. Results support the notion that areas of the right prefrontal cortex<span> are critical to the types of divergent semantic processing involved with creativity in this context.</span></p></div>","PeriodicalId":100287,"journal":{"name":"Cognitive Brain Research","volume":"25 1","pages":"Pages 240-250"},"PeriodicalIF":0.0,"publicationDate":"2005-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.cogbrainres.2005.05.013","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25167547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. De Diego Balaguer , N. Sebastián-Gallés , B. Díaz , A. Rodríguez-Fornells
{"title":"Morphological processing in early bilinguals: An ERP study of regular and irregular verb processing","authors":"R. De Diego Balaguer , N. Sebastián-Gallés , B. Díaz , A. Rodríguez-Fornells","doi":"10.1016/j.cogbrainres.2005.06.003","DOIUrl":"10.1016/j.cogbrainres.2005.06.003","url":null,"abstract":"<div><p>Although the age of acquisition of a language has an effect when learning a second language, the similarity between languages may also have a crucial role. The aim of the present study is to understand the influence of this latter factor in the acquisition of morphosyntactic information. With this purpose, two groups of highly proficient early Catalan–Spanish bilinguals were presented with a repetition-priming paradigm with regular and irregular verbs of Spanish. Catalan and Spanish have a similar suffix (<em>-o</em>) for regular verbs and completely different alternations for irregular verbs. Two types of irregular verbs were studied (semi-regular verbs with a systematic diphthong alternation, <em>sentir–siento</em>, and verbs with idiosyncratic changes, <em>venir–vengo</em><span>). Regular verbs showed the same centro-parietal N400 priming effect in the second-language speakers (L2) as in primary-language (L1) speakers. However, differences between groups, in the ERP pattern and the topography of the N400 effect, were observed for irregular morphology. In L1 speakers, the N400 effect was attenuated only for semi-regular verbs. In contrast, L2 speakers showed a reduced N400 priming effect in both irregular contrasts. This pattern of results suggests that the similarity between languages may help for similar structures but may interfere for dissimilar structures, at least when the two languages have very similar morphological systems.</span></p></div>","PeriodicalId":100287,"journal":{"name":"Cognitive Brain Research","volume":"25 1","pages":"Pages 312-327"},"PeriodicalIF":0.0,"publicationDate":"2005-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.cogbrainres.2005.06.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25193066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}