Biochimica et Biophysica Acta (BBA) - Mucoproteins and Mucopolysaccharides最新文献

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Hageman factor, a novel sialoglycoprotein with esterase activity Hageman因子,一种具有酯酶活性的新型唾液糖蛋白
Biochimica et Biophysica Acta (BBA) - Mucoproteins and Mucopolysaccharides Pub Date : 1965-07-01 DOI: 10.1016/0926-6534(65)90047-3
John G.G. Schoenmakers, R. Matze, C. Haanen, F. Zilliken
{"title":"Hageman factor, a novel sialoglycoprotein with esterase activity","authors":"John G.G. Schoenmakers,&nbsp;R. Matze,&nbsp;C. Haanen,&nbsp;F. Zilliken","doi":"10.1016/0926-6534(65)90047-3","DOIUrl":"10.1016/0926-6534(65)90047-3","url":null,"abstract":"<div><p>A novel esterase has been isolated from bovine plasma in a highly purified form. According to electrophoresis and ultracentrifugal sedimentation patterns it represents a homogeneous 7.1 S sialoglycoprotein being composed of 5.9% neutral carbohydrates, 4.8% aminosugars and 4.4% sialic acid. In catalytic amounts it normalizes the prolonged clotting time of plasma deficient in Hageman factor and exhibits a strong esterase activity towards <span><math><mtext>N-</mtext><mtext>benzoyl-</mtext><mtext>l</mtext><mtext>-arginine</mtext></math></span> ethyl ester.</p></div>","PeriodicalId":100163,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Mucoproteins and Mucopolysaccharides","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1965-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6534(65)90047-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16924991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 67
Chemistry of whole human glomerular basement membranes and of a soluble fraction prepared by trypsinization 整个人肾小球基底膜和胰蛋白酶化制备的可溶性部分的化学性质
Biochimica et Biophysica Acta (BBA) - Mucoproteins and Mucopolysaccharides Pub Date : 1965-07-01 DOI: 10.1016/0926-6534(65)90053-9
Charles F. Lange Jr., A.S. Markowitz
{"title":"Chemistry of whole human glomerular basement membranes and of a soluble fraction prepared by trypsinization","authors":"Charles F. Lange Jr.,&nbsp;A.S. Markowitz","doi":"10.1016/0926-6534(65)90053-9","DOIUrl":"10.1016/0926-6534(65)90053-9","url":null,"abstract":"","PeriodicalId":100163,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Mucoproteins and Mucopolysaccharides","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1965-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6534(65)90053-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16924995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 17
Kinetics of the enzymic dissociation of bacterial endotoxin 细菌内毒素酶解动力学
Biochimica et Biophysica Acta (BBA) - Mucoproteins and Mucopolysaccharides Pub Date : 1965-07-01 DOI: 10.1016/0926-6534(65)90054-0
William F. Vincent, J.A. Cameron
{"title":"Kinetics of the enzymic dissociation of bacterial endotoxin","authors":"William F. Vincent,&nbsp;J.A. Cameron","doi":"10.1016/0926-6534(65)90054-0","DOIUrl":"10.1016/0926-6534(65)90054-0","url":null,"abstract":"","PeriodicalId":100163,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Mucoproteins and Mucopolysaccharides","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1965-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6534(65)90054-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16404373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Isolation and identification of the glycosaminoglycans from fracture callus 骨折愈伤组织中糖胺聚糖的分离与鉴定
Biochimica et Biophysica Acta (BBA) - Mucoproteins and Mucopolysaccharides Pub Date : 1965-07-01 DOI: 10.1016/0926-6534(65)90045-X
C.A. Antonopoulos , B. Engfeldt , S. Gardell , S.-O. Hjertquist , K. Solheim
{"title":"Isolation and identification of the glycosaminoglycans from fracture callus","authors":"C.A. Antonopoulos ,&nbsp;B. Engfeldt ,&nbsp;S. Gardell ,&nbsp;S.-O. Hjertquist ,&nbsp;K. Solheim","doi":"10.1016/0926-6534(65)90045-X","DOIUrl":"10.1016/0926-6534(65)90045-X","url":null,"abstract":"<div><p>The glycosaminoglycans in fracture callus from rabbits have been isolated, and analysed with chemical and physical methods. Hyaluronic acid as well as chondroitin sulphate with infrared characteristics of both -4-sulphate and -6-sulphate were found. When callus of different degrees of maturation was studied, differences in the recovery of the total glycosaminoglycans as well as differences in the ratio between the recovered fractions were found, probably reflecting the different morphology of fracture callus of different ages.</p></div>","PeriodicalId":100163,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Mucoproteins and Mucopolysaccharides","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1965-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6534(65)90045-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16924989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 44
Non-dialyzable sialic acid compounds in ossifying and resting calf scapula cartilage 在骨化和静止的小腿肩胛骨软骨中不可透析的唾液酸化合物
Biochimica et Biophysica Acta (BBA) - Mucoproteins and Mucopolysaccharides Pub Date : 1965-07-01 DOI: 10.1016/0926-6534(65)90059-X
Abbas Othman Jibril, Arthur Lindenbaum
{"title":"Non-dialyzable sialic acid compounds in ossifying and resting calf scapula cartilage","authors":"Abbas Othman Jibril,&nbsp;Arthur Lindenbaum","doi":"10.1016/0926-6534(65)90059-X","DOIUrl":"10.1016/0926-6534(65)90059-X","url":null,"abstract":"","PeriodicalId":100163,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Mucoproteins and Mucopolysaccharides","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1965-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6534(65)90059-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16924999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
Heterogeniety of β-aspartyl-oligosaccharides derived from ovalbumin 卵清蛋白衍生的β-天冬氨酸寡糖的异质性
Biochimica et Biophysica Acta (BBA) - Mucoproteins and Mucopolysaccharides Pub Date : 1965-07-01 DOI: 10.1016/0926-6534(65)90058-8
Leon Cunningham, John D. Ford, John M. Rainey
{"title":"Heterogeniety of β-aspartyl-oligosaccharides derived from ovalbumin","authors":"Leon Cunningham,&nbsp;John D. Ford,&nbsp;John M. Rainey","doi":"10.1016/0926-6534(65)90058-8","DOIUrl":"10.1016/0926-6534(65)90058-8","url":null,"abstract":"","PeriodicalId":100163,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Mucoproteins and Mucopolysaccharides","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1965-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6534(65)90058-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81289051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 26
Interaction of polylysine with soluble components of human erythrocyte membranes 聚赖氨酸与人红细胞膜可溶性组分的相互作用
Biochimica et Biophysica Acta (BBA) - Mucoproteins and Mucopolysaccharides Pub Date : 1965-07-01 DOI: 10.1016/0926-6534(65)90051-5
D. Danon , C. Howe, L.T. Lee
{"title":"Interaction of polylysine with soluble components of human erythrocyte membranes","authors":"D. Danon ,&nbsp;C. Howe,&nbsp;L.T. Lee","doi":"10.1016/0926-6534(65)90051-5","DOIUrl":"https://doi.org/10.1016/0926-6534(65)90051-5","url":null,"abstract":"<div><p></p><ul><li><span>1.</span><span><p>1. The interactions of poly-<span>l</span>-lysine with soluble erythrocyte components and with Collocalia mucoid, a sialoprotein of avian origin, were studied by electrophoresis and immuno-electrophoresis in agar gel.</p></span></li><li><span>2.</span><span><p>2. Polylysine combined with erythrocyte membrane glycoprotein and with Collocalia mucoid to form visible precipitates in agar gel; erythrocyte fractions devoid of glycoprotein failed so to react.</p></span></li><li><span>3.</span><span><p>3. A precipitate of virus receptor substance with polylysine could be quantitatively redissolved by the addition of poly-<span>l</span>-aspartic acid to the mixture. Whether this change in solubility occurred as a result of displacement of polylysine from the glycoprotein or by the formation of soluble complexes could not be established.</p></span></li><li><span>4.</span><span><p>4. Neuraminidase (EC 3.2.1.18) treatment of erythrocyte glycoproteins and Collocalia mucoid greatly reduced or abolished their capacity to precipitate with polylysine.</p></span></li><li><span>5.</span><span><p>5. The findings suggest that <em>N</em>-acetylneuraminic acid in the acid glycoprotein of erythrocyte membranes is an important factor in the agglutination of erythrocytes by polybases, a phenomenon thought to have some bearing on intravascular thrombus formation.</p></span></li></ul></div>","PeriodicalId":100163,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Mucoproteins and Mucopolysaccharides","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1965-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6534(65)90051-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91683210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 32
Analysis of mucopolysaccharides in partially aqueous media 部分含水介质中粘多糖的分析
Biochimica et Biophysica Acta (BBA) - Mucoproteins and Mucopolysaccharides Pub Date : 1965-07-01 DOI: 10.1016/0926-6534(65)90055-2
Klaus E. Kuettner , Arthur Lindenbaum
{"title":"Analysis of mucopolysaccharides in partially aqueous media","authors":"Klaus E. Kuettner ,&nbsp;Arthur Lindenbaum","doi":"10.1016/0926-6534(65)90055-2","DOIUrl":"10.1016/0926-6534(65)90055-2","url":null,"abstract":"","PeriodicalId":100163,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Mucoproteins and Mucopolysaccharides","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1965-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6534(65)90055-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15331888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 30
Studies on glycoproteins XII. About glycosidic-ester linkages in submaxillary gland glycoproteins prepared from sheep 糖蛋白的研究羊颌下腺糖蛋白中糖苷-酯键的研究
Biochimica et Biophysica Acta (BBA) - Mucoproteins and Mucopolysaccharides Pub Date : 1965-07-01 DOI: 10.1016/0926-6534(65)90044-8
J.S. Best, V.P. Bhavanandan, A. Gottschalk
{"title":"Studies on glycoproteins XII. About glycosidic-ester linkages in submaxillary gland glycoproteins prepared from sheep","authors":"J.S. Best,&nbsp;V.P. Bhavanandan,&nbsp;A. Gottschalk","doi":"10.1016/0926-6534(65)90044-8","DOIUrl":"10.1016/0926-6534(65)90044-8","url":null,"abstract":"<div><p>OSM prepared from sheep is known to contain O-glycosidic linkages involving the reducing group of <em>N</em>-acetylgalactosamine and the hydroxyl groups of serine and threonine. It is the aim of this paper to establish whether or not in addition to this linkage another type of alkali-labile linkage, in particular a glycosidic-ester linkage, is present in OSM.</p><p>In the first set of experiments it was found that the release of 35.2% of <em>N</em>-acetylgalactosamine, when OSM was kept at pH 8.0 and 42° for 120 h, was matched by the loss of an equimolar amount of serine and threonine without a significant change in the other amino acids. In a second set of experiments it was shown that on treating OSM with 0.1 N NaOH at 4° the decrease of bound hexosamine with time was linear. Finally, glycopeptides prepared by trypsin (EC 3.4.4.4) or pronase action on OSM were treated with LiBH<sub>4</sub> in tetrahydrofuran. No significant difference in the dicarboxylic amino acids before and after such treatment was observed. Only traces of homoserine and <em>α</em>-amino-<em>δ</em>-hydroxy-<em>n</em>-valeric acid were detectable after LiBH<sub>4</sub> reduction.</p><p>Since the LiBH<sub>4</sub> treatment of trypsinized OSM prepared from Australian sheep resulted in the loss of 35% of the dicarboxylic acid content, the suggestion is made that the fine structure of the ovine submaxillary glycoproteins may vary with the age of the animals. In Australia, lambs of an average age of 4 months were used for the work; in Europe only sheep of three years or more are slaughtered. Similar differences with age have been described for the fine structure of the chondroitin sulphates composing human hyaline cartilage.</p></div>","PeriodicalId":100163,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Mucoproteins and Mucopolysaccharides","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1965-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6534(65)90044-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16924988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
A new glycopeptide containing hydroxyproline and sarcosine in human urine 羟脯氨酸一种在人尿中含有羟脯氨酸和肌氨酸的新糖肽
Biochimica et Biophysica Acta (BBA) - Mucoproteins and Mucopolysaccharides Pub Date : 1965-07-01 DOI: 10.1016/0926-6534(65)90061-8
M. George Cherian, A.N. Radhakrishnan
{"title":"A new glycopeptide containing hydroxyproline and sarcosine in human urine","authors":"M. George Cherian,&nbsp;A.N. Radhakrishnan","doi":"10.1016/0926-6534(65)90061-8","DOIUrl":"10.1016/0926-6534(65)90061-8","url":null,"abstract":"","PeriodicalId":100163,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Mucoproteins and Mucopolysaccharides","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1965-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6534(65)90061-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16925741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 13
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