Isolation and identification of the glycosaminoglycans from fracture callus

C.A. Antonopoulos , B. Engfeldt , S. Gardell , S.-O. Hjertquist , K. Solheim
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引用次数: 44

Abstract

The glycosaminoglycans in fracture callus from rabbits have been isolated, and analysed with chemical and physical methods. Hyaluronic acid as well as chondroitin sulphate with infrared characteristics of both -4-sulphate and -6-sulphate were found. When callus of different degrees of maturation was studied, differences in the recovery of the total glycosaminoglycans as well as differences in the ratio between the recovered fractions were found, probably reflecting the different morphology of fracture callus of different ages.

骨折愈伤组织中糖胺聚糖的分离与鉴定
对家兔骨折愈伤组织中的糖胺聚糖进行了分离,并用化学和物理方法进行了分析。发现透明质酸和硫酸软骨素具有-4-硫酸盐和-6-硫酸盐的红外特征。在对不同成熟程度的愈伤组织进行研究时,发现总糖胺聚糖的回收率存在差异,回收组分之间的比例也存在差异,这可能反映了不同年龄的骨折愈伤组织形态的不同。
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