Archives of Gerontology and Geriatrics Plus最新文献

{"title":"Cognitive decline gap between male and female in Indian context: Examining the contribution of underlying factors using non-linear decomposition analysis","authors":"Subhadeep Saha,&nbsp;Priya Das,&nbsp;Tanu Das,&nbsp;Partha Das,&nbsp;Tamal Basu Roy","doi":"10.1016/j.aggp.2024.100103","DOIUrl":"10.1016/j.aggp.2024.100103","url":null,"abstract":"<div><h3>Background</h3><div>Cognitive decline denotes the condition of having memory loss, reduced or slower thinking skills. It is an alarming issue with the increasing age of individuals and sometimes it hinders the smooth functioning of daily activities in life. Affirmations from both developed and developing countries manifest that older people are at risk of cognitive decline; however, the study about male-female differential remained scanty. So, the study examines gender-specific differences in cognitive decline among middle-aged and older adults by identifying the significant covariates responsible for the change in cognitive decline through the FDA.</div></div><div><h3>Methods</h3><div>The study used information collected from 52,569 participants (females 26,665 and males 25,904) aged 45 years and above from the latest cross-sectional dataset of LASI. Descriptive statistics, multivariable logistic regression, and FDA techniques were utilized.</div></div><div><h3>Results</h3><div>Multivariable logistic regression revealed that female individuals had 1.90 times [95% CI: (1.77-2.05)] higher odds of cognitive decline than male individuals. In addition, the FDA revealed that school attainment alone was found enough to narrate the difference in the pervasiveness of cognitive decline among individuals between males and females by 54.75%. Marital status, working status, and reading habits were found to express a profound impact on the male-female gap in the prevalence of cognitive decline by 9.41%, 6.47%, and 12.25% respectively.</div></div><div><h3>Conclusions</h3><div>Findings suggest that there is a need for comprehensive public service intervention like community healthcare and formulation of various health programs to address the cognitive decline, more so for female individuals without neglecting the male ones.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"1 4","pages":"Article 100103"},"PeriodicalIF":0.0,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142704804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Do healthy older adults use SNS? Focus on LINE, Facebook, Twitter (now X), and Instagram","authors":"Kanon Tsukada ,&nbsp;Tomoya Takahashi ,&nbsp;Yuho Shimizu ,&nbsp;Yan Li ,&nbsp;Toshihito Tsuchiya ,&nbsp;Kiyo Kawakubo ,&nbsp;Tomoya Sagara ,&nbsp;Koki Ito ,&nbsp;Tomoki Furuya ,&nbsp;Hiroyuki Suzuki","doi":"10.1016/j.aggp.2024.100096","DOIUrl":"10.1016/j.aggp.2024.100096","url":null,"abstract":"<div><h3>Background</h3><div>The use of social networking services (SNS) by older adults within the context of the digital divide has become a hot topic. Several studies have shown that SNS use among older adults is related to their health status; however, few studies have examined the association between health and specific SNS platforms.</div></div><div><h3>Objective</h3><div>This study investigates the relationship between older adults’ use of four major SNS platforms in Japan (LINE, Facebook, Twitter [now X], and Instagram) and the health of older adults. Subjective health and frequency of going out were used as health indicators. Method: A survey was conducted among participants in a health promotion program for older adults in Tokyo between 2020 and 2022. A total of 391 older adults participated in the study (<em>M</em> = 72.11 years, 65–86 years, 363 women).</div></div><div><h3>Results</h3><div>Logistic regression analysis revealed that subjective health was higher in users of Facebook, Twitter [now X], and Instagram (but not LINE) compared to non-users. Frequency of going out was not associated with SNS use.</div></div><div><h3>Conclusions</h3><div>Older adults with higher subjective health may be more likely to use SNS platforms due to their willingness to learn new skills and actively participate in social activities. Additionally, SNS may help improve the health of older adults by enabling communication with distant family and friends, even for those who are unable to go out frequently due to health problems.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"1 4","pages":"Article 100096"},"PeriodicalIF":0.0,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142704803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"“There's a lot of factors”: Researcher reflections on using I-poetry to empathetically understand vaccine hesitant individuals","authors":"Bryce Van Vleet M.S. ,&nbsp;Heather R. Fuller Ph.D. ,&nbsp;Andrea Huseth-Zosel Ph.D.","doi":"10.1016/j.aggp.2024.100100","DOIUrl":"10.1016/j.aggp.2024.100100","url":null,"abstract":"<div><h3>Background</h3><div>Despite higher vaccination rates compared to other age groups, many US older adults remain under-vaccinated against preventable diseases leading to increased risk of serious illness, hospitalization, or death posed from disease. This study investigates the underlying reasons for older adults not getting vaccinated.</div></div><div><h3>Methods</h3><div>From a larger interview study conducted in North Dakota, eight older adults (Mean Age = 73) were identified as being vaccine hesitant. Participants were asked, “How do you decide about whether or not to get a specific vaccine?” Then, participants' responses were analyzed using the I-poetry qualitative methodology, which involves creating a poem from interview transcripts to capture the essence of participants' experiences.</div></div><div><h3>Results</h3><div>Poetic findings clarify interacting sources of immunization unease and highlight potential intervention avenues for medical professionals. Specifically, the poetic analysis revealed themes of mistrust in the healthcare system, preference for natural immunity, and concerns about vaccine side effects. The study suggests that healthcare professionals should consider using empathetic communication strategies to address vaccine hesitancy in older adults.</div></div><div><h3>Conclusions</h3><div>Understanding vaccine hesitancy as a tapestry instead of individual factors may be more useful for older adults who culminate their hesitant beliefs from prior life experiences. Additionally, to improve trust in healthcare providers, it is suggested that more first-person narratives of older adult experiences are used and solicited by healthcare providers. Possible interventions are discussed.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"1 4","pages":"Article 100100"},"PeriodicalIF":0.0,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142651605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The link between periodontitis and Alzheimer's disease – Brunei context","authors":"Sarah Nabihah Mohamad Fadzli ,&nbsp;Jagjit Singh Dhaliwal ,&nbsp;Faiza Alam ,&nbsp;Jacqueline Kamaluddin ,&nbsp;Hanif Abdul Rahman","doi":"10.1016/j.aggp.2024.100097","DOIUrl":"10.1016/j.aggp.2024.100097","url":null,"abstract":"<div><h3>Aim</h3><div>The study aims to explore the relationship between periodontitis and Alzheimer's disease, focusing on the association and their potential impact on cognitive health.</div></div><div><h3>Methods</h3><div>A retrospective study was conducted utilizing data obtained from the Brunei Health Information Management System (Bru-HIMS). The research study examined the correlation between periodontitis and Alzheimer's disease in individuals admitted to government healthcare settings between January 2014 and December 2023. Logistic regression and survival analysis were applied.</div></div><div><h3>Results</h3><div>After diagnosis of periodontitis, 81.6 %, 59.2 % and 40.8 % developed Alzheimer's disease after 1–3- and 5-years, respectively. Women (34.3 %) had significantly lower proportion of developing Alzheimer's disease after 5 years compared to men (46.3 %). Furthermore, those with history of tooth extraction has a high risk of developing Alzheimer's disease (Adjusted Hazard Ratio = 5.00; 95 % CI: 2.04, 12.28; <em>p</em> &lt; 0.001).</div></div><div><h3>Conclusion</h3><div>The study highlights the importance of understanding periodontal health in Alzheimer's patients and suggests further research and targeted interventions to mitigate its impact on cognitive function.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"1 4","pages":"Article 100097"},"PeriodicalIF":0.0,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142651607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spirituality, forgiveness and self-esteem throughout adulthood in France","authors":"Agli Océane ,&nbsp;Bailly Nathalie ,&nbsp;Cuervo-Lombard Christine-Vanessa","doi":"10.1016/j.aggp.2024.100098","DOIUrl":"10.1016/j.aggp.2024.100098","url":null,"abstract":"<div><h3>Purpose</h3><div>It appears that spirituality, forgiveness, and self-esteem are important values which transcend human actions. This transversal study aims to observe spirituality, forgiveness, and self-esteem during aging.</div></div><div><h3>Methods</h3><div>A quantitative protocol was conducted with 206 participants divided into two groups: younger adults (M = 23.05 years old) and older people (M = 73.09 years old). Three tests measured spirituality, forgiveness and self-esteem.</div></div><div><h3>Principal results</h3><div>Results showed that older people have higher scores than younger adults in spirituality (peace dimension), forgiveness (transcendence and emotional factors) and self-esteem. Moreover, all dimensions of spirituality (peace, mean, faith) were correlated with the transcendence and emotional factors of forgiveness and with self-esteem during aging.</div></div><div><h3>Major conclusion</h3><div>It seems that with age, individuals have a better self-esteem linked to more pronounced spiritual needs (sense of peace, meaning of life, faith) and manage to forgive more unconditionally with less resentment than younger people.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"1 4","pages":"Article 100098"},"PeriodicalIF":0.0,"publicationDate":"2024-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142651606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Circulating miR-323–3p as a novel potential plasma biomarker for multimorbidity burden and cognitive decline in middle-aged and older adults: Results from the national institute for longevity sciences–longitudinal study of aging in Japan","authors":"Wei-Min Chu ,&nbsp;Mio Goto ,&nbsp;Keiko Kabetani ,&nbsp;Yukiko Nishita ,&nbsp;Shu Zhang ,&nbsp;Hiroshi Shimokata ,&nbsp;Meng-Chih Lee ,&nbsp;Akiko Satoh ,&nbsp;Rei Otsuka","doi":"10.1016/j.aggp.2024.100099","DOIUrl":"10.1016/j.aggp.2024.100099","url":null,"abstract":"<div><h3>Background</h3><div>Several circulating microRNAs (miRNAs) in the blood are indicators of chronic diseases, but their association with multimorbidity burden is unknown. The aim of this study was to assess the association of plasma levels of circulating miR-323–3p and miR-135–3p with age, cognitive performance, and number of comorbidities in middle-aged and older individuals.</div></div><div><h3>Methods</h3><div>Data from 295 community dwellers (≥40 years) who participated in the second wave (2000‒2002) of the National Institute for Longevity Sciences-Longitudinal Study of Aging in Japan were analyzed. miRNAs were isolated from the plasma, and miR-323–3p and miR-135–3p levels were measured using quantitative reverse-transcription polymerase chain reaction and normalized, with miR-16 as an endogenous reference gene. Cognitive performance was assessed using the Information and Similarities subtests and the Digit Symbol Substitution Test of the Wechsler Adult Intelligence Scale-Revised Short Form (WAIS-R-SF). Correlation tests and multivariate general linear regression analyses were performed to examine the relationship among circulating miRNA levels, burden of multimorbidity, and cognitive performance.</div></div><div><h3>Results</h3><div>The mean age of the participants was 59.15 ± 10.26 years. Pearson's correlation analysis revealed that the miR-323–3p level positively correlated with age and number of comorbidities but negatively correlated with WAIS-R-SF subtest performance. In men, miR-323–3p level negatively correlated with the performance of all three WAIS-R-SF subtests. The general linear regression analysis showed that the miR-323–3p level increased in participants with four comorbidities compared with those with one comorbidity.</div></div><div><h3>Conclusion</h3><div>Circulating miR-323–3p level is associated with the burden of multimorbidity and decreased cognitive performance in middle-aged and older adults.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"1 4","pages":"Article 100099"},"PeriodicalIF":0.0,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142704805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The state of lipid metabolism in patients with diabetic nephropathy","authors":"Lola Daminova MD, PhD, DSc ,&nbsp;Sitorakhon Muminova PhD ,&nbsp;Bakhodir Nigmonov PhD","doi":"10.1016/j.aggp.2024.100095","DOIUrl":"10.1016/j.aggp.2024.100095","url":null,"abstract":"<div><h3>Aim</h3><div>This study aimed to evaluate the state of lipid metabolism in patients with diabetic nephropathy.</div></div><div><h3>Methods</h3><div>In this open label, randomised, prospective study. The study included 120 patients with type 2 diabetes, whose average age was 58.79 ± 1.27 years. In general, the average diabetes experience was 7 ± 3.16 years, HbA1C-9.3 ± 1.82 %, BMI-28.05 ± 3.45. Non-HDL cholesterol levels were calculated (non-HDL cholesterol = total cholesterol - HDL).</div></div><div><h3>Results</h3><div>As a result of the analysis, a negative relationship of moderate strength was revealed between eGFRcr levels in the blood of TCh (<em>r</em> = -0.32; <em>p</em> &lt; 0.01), triglycerides (<em>r</em> = -0.51; <em>p</em> &lt; 0.018), non-HDL (<em>r</em> = –0.44; <em>p</em> &lt; 0.01) and weak positive association with HDL (<em>r</em> = 0.28; <em>p</em> = 0.01). Negative relationships were also established between the A/Cr index and the blood level of TCh (<em>r</em> = -0.37; <em>p</em> &lt; 0.01), triglycerides (<em>r</em> = –0.42; <em>p</em> &lt; 0.01), non-HDL (<em>r</em> = – 0.35; <em>p</em> &lt; 0.01)/</div></div><div><h3>Conclusion</h3><div>Therefore, in patients with type 2 diabetes, it is advisable to determine the level of TG in the blood even with reference or slightly elevated levels of TG and non-HDL to predict DN.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"1 4","pages":"Article 100095"},"PeriodicalIF":0.0,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142651604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between atrial fibrillation and periodontal disease: A bioinformatics analysis","authors":"Takahiro Kamihara ,&nbsp;Yoshihiro Kugimiya ,&nbsp;Takuya Omura ,&nbsp;Shinji Kaneko ,&nbsp;Ken Tanaka ,&nbsp;Akihiro Hirashiki ,&nbsp;Manabu Kokubo ,&nbsp;Atsuya Shimizu","doi":"10.1016/j.aggp.2024.100093","DOIUrl":"10.1016/j.aggp.2024.100093","url":null,"abstract":"<div><h3>Introduction</h3><div>Atrial fibrillation (AF), which is an aging disease, and periodontal disease (PD) are prevalent, and AF and PD may be associated with each other. Inflammation plays a role in the two pathologies. However, there is a need for a deeper understanding of the mechanisms associated with these conditions.</div></div><div><h3>Methods</h3><div>A bioinformatics analysis was performed to compare gene expression profiles in the blood and left atrial tissue samples of patients with AF and in the blood samples of patients with PD. Our analysis involved comparing gene expression profiles between patients with AF, those with sinus rhythm, and individuals with and without PD. This comparative approach enabled us to identify upregulated genes in both the AF and PD cohorts.</div></div><div><h3>Results</h3><div>The expression of 40 genes was upregulated in patients with AF and PD, with a significant enrichment for genes associated with inflammation. Notably, a network analysis revealed distinct functional associations among these genes. Interestingly, the expressions of three lysosome-related genes in all analyzed tissues (AF blood, PD blood, and AF left atrium) were upregulated.</div></div><div><h3>Conclusion</h3><div>Inflammation played a role in AF and PD. Further, based on the upregulated expression of lysosome-related genes across all samples that were evaluated, in addition to inflammation, lysosomal function had a possible role in the co-existence of the two diseases.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"1 4","pages":"Article 100093"},"PeriodicalIF":0.0,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142651602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between the type of dental prosthesis and the masticatory performance of institutionalized patients: A cross-sectional study.","authors":"Antonia Christina Samiou ,&nbsp;Maria Kokoti ,&nbsp;Theodora Slini ,&nbsp;Vassiliki Anastassiadou ,&nbsp;Bernd Kordaß ,&nbsp;Athina Bakopoulou","doi":"10.1016/j.aggp.2024.100094","DOIUrl":"10.1016/j.aggp.2024.100094","url":null,"abstract":"<div><div>This cross-sectional study aimed to determine the chewing ability of 97 institutionalized older adults and its relevance to their status of dentition and type of prosthetic rehabilitation. The participants were categorized according to their dental status. The chewing ability was determined by semi-quantitative evaluation of a colour-changeable chewing gum and by recording the personal perception of the participants on a similar scale. The colorimetric means of the participants was significantly lower than the perception means. One-third of the participants had at least one jaw restored with complete dentures, while 17% were restored with tooth-supported or implant-supported fixed partial dentures. Based on the colorimetric method, edentulous participants displayed significantly lower chewing performance compared to all other groups. Additionally, participants with at least one complete denture exhibited weaker chewing function than those with natural teeth or fixed partial dentures<strong>.</strong> The age and sex of the participants had no further impact on the results. As the institutionalized elderly seem to overestimate their chewing efficiency, the colour changeable chewing gum could be used in nursing homes, as a simple method to determine their real masticatory function status and improve their dental care.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"1 4","pages":"Article 100094"},"PeriodicalIF":0.0,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142651603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a medication status check sheet to identify patients with poor understanding of their medications: A multicenter study in Japan","authors":"Tomoya Obara ,&nbsp;Ryota Kumaki ,&nbsp;Hiroshi Shinonaga ,&nbsp;Yasushi Takai ,&nbsp;Keiichiro Higashi ,&nbsp;Maho Tatsumi ,&nbsp;Hiroko Otsubo ,&nbsp;Makoto Akao ,&nbsp;Koji Muto ,&nbsp;Akie Yamaguchi ,&nbsp;Yoshitomo Shimazaki ,&nbsp;Keiko Kishimoto","doi":"10.1016/j.aggp.2024.100092","DOIUrl":"10.1016/j.aggp.2024.100092","url":null,"abstract":"<div><h3>Background</h3><div>One of the causes of polypharmacy is aimless medication use due to poor understanding of medications. However, some patients do not adequately understand the indication for medications and adverse effects of polypharmacy. This study aimed to develop a screening tool, the medication status check (MSC), to identify patients with poor understanding of their medications to reduce aimless medication use in Japan.</div></div><div><h3>Methods</h3><div>This multicenter, prospective, observational study was conducted in nine hospitals in Japan. Inpatients aged ≥75 years were surveyed between September 2023 and March 2024. A chi-squared test was conducted to determine the relationship of the 19 MSC draft items with poor and good understanding of medications. A receiver operating characteristic (ROC) analysis was then performed using significant questions (i.e., those with a <em>P</em>-value of &lt;0.05), and cut-off values were obtained.</div></div><div><h3>Results</h3><div>Overall, 3 items, comprising 2 of the draft MSC questions and the use of ≥5 medications, were designated as the MSC-3. The area under the ROC curve was 0.686 (95 % confidence interval: 0.582–0.778, <em>P</em> &lt; 0.001), indicating that the MSC-3 was useful as a screening tool. When at least one of the MSC-3 items was met, this approach resulted in a sensitivity of 93.1 % and specificity of 21.7 % in identifying the need for polypharmacy intervention.</div></div><div><h3>Conclusions</h3><div>Use of the MSC-3 will enable pharmacists to intervene at an early stage, potentially contributing to a reduction in the incidence of polypharmacy.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"1 4","pages":"Article 100092"},"PeriodicalIF":0.0,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142593025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}