Archives of Gerontology and Geriatrics Plus最新文献

{"title":"The AWGS 2025 update: From sarcopenia diagnosis to life-course muscle health promotion","authors":"Liang-Kung Chen MD, PhD","doi":"10.1016/j.aggp.2025.100227","DOIUrl":"10.1016/j.aggp.2025.100227","url":null,"abstract":"","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"2 4","pages":"Article 100227"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145684222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Personalized multi-modal interfaces for cognitive aging: A narrative review of design and technological innovations","authors":"Riya Bhattacharya ,&nbsp;Debajyoti Bose ,&nbsp;Raul V. Rodriguez ,&nbsp;Hemachandran K ,&nbsp;Kashif R. Siddique","doi":"10.1016/j.aggp.2025.100206","DOIUrl":"10.1016/j.aggp.2025.100206","url":null,"abstract":"<div><div>This narrative review examines the design and execution of adaptive multi-modal interfaces aimed at improving autonomy and cognitive health in aging populations. This is a pressing necessity as the worldwide demographic of those aged 65 and older is anticipated to exceed 1.5 billion by 2050. By incorporating modalities like as speech, touch, gesture, and haptic feedback, these interfaces adaptively customize interactions to accommodate age-related sensory, motor, and cognitive impairments. This review integrates interdisciplinary literature from human-computer interaction, gerontology, and artificial intelligence, synthesizing evidence on cognitive and functional requirements, user-centred design principles, and enabling technologies such as wearable sensors and AI-driven predictive models. This demonstrates 95 % accuracy in predicting user preferences. It emphasizes that tailored interfaces enhance usability by 30 % for older adults and facilitate independent living, especially for individuals with mild cognitive impairment. This evaluation is presented due to the increasing demand for accessible technologies that address accessibility disparities and foster equitable cognitive engagement among various aging demographics. Additionally, this work also identifies research gaps, including the necessity for longitudinal studies and unbiased algorithms, thereby offering a thorough framework for advancements in adaptive systems. It underscores ethical considerations such as data privacy and cultural sensitivity to promote inclusive design.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"2 4","pages":"Article 100206"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145057101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Caregiver burden, job stress, and coping strategies in work–family conflict among sandwiched caregivers in long-term care settings: A cross-sectional study","authors":"Ayumi Honda Ph.D.","doi":"10.1016/j.aggp.2025.100208","DOIUrl":"10.1016/j.aggp.2025.100208","url":null,"abstract":"<div><h3>Background</h3><div>Longer life expectancy, along with the delay of marriage and childbearing, has led to an increase in the number of sandwiched caregivers. Employees who are responsible for both childcare and eldercare are more likely to experience work- and caregiving-related stress, which can result in work–family conflict. However, sandwiched caregivers who adopt caregiving-related coping strategies may experience lower conflict between work and family. This exploratory study aimed to investigate the associations of caregiver burden, job stress, and coping strategies with work–family conflict among sandwiched caregivers, and to examine whether caregiving-related coping strategies are associated with lower such conflict.</div></div><div><h3>Methods</h3><div>This cross-sectional study was conducted using a self-administered questionnaire. The study participants were 72 sandwiched caregivers working in long-term care settings in Japan. All participants had at least one parent aged 65 years or older and were rearing at least one child younger than 18 years. Simple linear regression analysis was performed to assess the associations of work-to-family and family-to-work conflict with caregiver characteristics, caregiving tasks, caregiver burden, job stress, and caregiving-related coping strategies.</div></div><div><h3>Results</h3><div>Greater caregiver burden and job overload were both commonly associated with work-to-family and family-to-work conflict. In addition, having caregiving-related strategies and behaviors in seeking assistance from others was associated with lower work-to-family conflict.</div></div><div><h3>Conclusion</h3><div>Individual coping strategies alone may not be sufficient to promote caregiver well-being. Therefore, maintaining social connections for formal and informal support, as well as implementing flextime or providing a flexible workplace for family-supportive practices, may also be necessary.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"2 4","pages":"Article 100208"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145220124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Auditory-cognitive markers of mild cognitive impairment: Evidence from a systematic review","authors":"Neelesh Benet,&nbsp;Vijay Kumar,&nbsp;Srikar Vijayasarthy","doi":"10.1016/j.aggp.2025.100231","DOIUrl":"10.1016/j.aggp.2025.100231","url":null,"abstract":"<div><h3>Introduction</h3><div>Mild Cognitive Impairment (MCI) represents an intermediate stage between normal aging and dementia. Emerging evidence suggests that central auditory processing (CAP) deficits may appear even earlier and serve as sensitive indicators of cognitive decline.</div></div><div><h3>Objective</h3><div>The literature was reviewed to examine the CAP abilities in individuals with MCI. It also examines existing MCI diagnostic guidelines from various countries to assess how CAP assessments are currently integrated in clinical protocols.</div></div><div><h3>Method</h3><div>A systematic literature search was conducted using PubMed/Medline, Cochrane Library, Scopus and Google Scholar (Jan 2014–Dec 2024). Key search terms included “temporal resolution,” “dichotic,” “speech-in-noise,” “auditory working memory,” <strong>“central auditory processing disorder,” “auditory scene analysis,” “temporal gap detection,” “auditory discrimination,”</strong> and “mild cognitive impairment.” Only those studies were shortlisted if they investigated CAP in elderly individuals with MCI. Articles outlining MCI diagnostic guidelines were also considered.</div></div><div><h3>Result</h3><div>Twenty-nine articles met the inclusion criteria. Twenty-three indicated a significant CAP deficit in persons with MCI. Studies consistently show MCI is associated with CAP impairments. Tests like Gap Detection Threshold, Dichotic Digit Test, Sentence-in-Noise, and Digits Backward effectively distinguish MCI patients from healthy controls. Six articles focused on diagnostic guidelines from various countries. Despite many studies showing CAP deficits in MCI, leading diagnostic guidelines do not include CAP tests.</div></div><div><h3>Conclusion</h3><div>CAP tests hold promise for the early detection of MCI. Integrating them into clinical guidelines can improve diagnostic sensitivity which may delay its progression to Alzheimer’s disease. Despite their diagnostic utility, such tests are not included in the MCI diagnostic frameworks.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"2 4","pages":"Article 100231"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145617839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Restrictions in community-based care services and the effect on family caregivers during the COVID-19 pandemic: A mixed-methods study","authors":"Ayumi Honda Ph.D. ,&nbsp;Yin Liu Ph.D. ,&nbsp;Mayo Ono Ph.D ,&nbsp;Takahiro Nishida R.N ,&nbsp;Tatsuya Tsukigi ,&nbsp;Elizabeth B. Fauth Ph.D. ,&nbsp;Sumihisa Honda Ph.D.","doi":"10.1016/j.aggp.2025.100205","DOIUrl":"10.1016/j.aggp.2025.100205","url":null,"abstract":"<div><h3>Background</h3><div>This mixed-methods study aimed to examine the effects of restrictions in the utilization of community-based care services on family caregivers during the COVID-19 pandemic.</div></div><div><h3>Methods</h3><div>We recruited from community-based care services 200 family caregivers who were living with an older care recipient. We first conducted thematic analyses based on open-ended responses to questions regarding the impact of restrictions in the utilization of community-based care services. We then extracted themes to examine and determine patterns across caregiving characteristics. Next, we conducted linear regression analysis to examine associations between impact of restrictions and caregiving contexts.</div></div><div><h3>Results</h3><div>We identified 11 themes regarding the impact of restrictions in the utilization of community-based care services. Most frequently reported impact included “the family caregiver cannot bathe the older person at home” and that “the family caregiver cannot go to work/income decreases”. Caregiver employment, more caregiving tasks, and more behavioral and psychological symptoms of dementia of the care recipient were associated with harmful impacts resulting from restrictions in the utilization of community-based care services.</div></div><div><h3>Conclusion</h3><div>During the COVID-19 pandemic, family caregivers sometimes felt ill equipped to provide home care. Caregiver employment, more caregiving tasks, and more BPSD were factors associated with the negative impact from restricted community-based care service use.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"2 4","pages":"Article 100205"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145095970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Healthcare service utilization and treatment costs among elderly citizens in Bangladesh","authors":"Abdur Razzaque Sarker","doi":"10.1016/j.aggp.2025.100218","DOIUrl":"10.1016/j.aggp.2025.100218","url":null,"abstract":"<div><div>Bangladesh’s population is aging rapidly, with 8 % of the population currently aged 60 or older, projected to reach 21.5 million by 2030. Elderly citizens face significant health challenges and healthcare costs, increasing demands on the healthcare system. This study assessed self-reported illnesses, treatment costs, and factors influencing healthcare utilization among the elderly in Bangladesh. A cross-sectional survey of 585 elderly citizens (aged 60+ as per Bangladesh’s National Policy on Elderly People) was conducted in Tangail district from December 2019 to February 2020. Descriptive statistics and logistic regression analysis were used to analyze factors associated with healthcare utilization. We found about 92 % of elderly respondents reported illness, with hypertension, ulcers, pain, and diabetes being most common. Average treatment cost per case was BDT 7714 (SD ± 32,472; Median: 1809; IQR: 4926), with medicine as the largest cost driver. Factors such as education, marital status, residence, and wealth were significantly associated with healthcare utilization. These findings provide valuable baseline health data for elderly citizens and can guide policymakers in designing appropriate disease control strategies to improve their health outcomes. Financial risk protection mechanisms, such as the introduction of social health insurance, should be considered to ensure healthcare is both affordable and accessible for all elderly citizens.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"2 4","pages":"Article 100218"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145320797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between IL-17 and sarcopenia in older adults","authors":"Everson de Cássio Robello ,&nbsp;Gabriela Cabett Cipolli ,&nbsp;Natália Almeida Lima ,&nbsp;Isabela Fernandes Nonato ,&nbsp;Mônica Sanches Yassuda ,&nbsp;Danillo Magalhães Xavier Assunção ,&nbsp;Ronei Luciano Mamoni ,&nbsp;Andréia de Oliveira Pain ,&nbsp;Ana Maria Kemp ,&nbsp;Richard C. Oude Voshaar ,&nbsp;Gustavo Duque ,&nbsp;Ivan Aprahamian","doi":"10.1016/j.aggp.2025.100200","DOIUrl":"10.1016/j.aggp.2025.100200","url":null,"abstract":"<div><h3>Background</h3><div>Chronic low-grade inflammation has been implicated as a potential contributor to sarcopenia, but the specific inflammatory mediators involved remain under investigation. This study explores the association between serum interleukin-17 levels and sarcopenia in older outpatients without pre-existing inflammatory or autoimmune diseases.</div></div><div><h3>Methods</h3><div>A cross-sectional study was conducted using data from the MiMiCS-FRAIL cohort. Sarcopenia was defined according to the European Working Group on Sarcopenia in Older People 2 criteria. IL-17 plasma levels were measured using enzyme-linked immunosorbent assay (ELISA). A multivariate binary logistic regression model was used to assess the association between sarcopenia and IL-17 levels.</div></div><div><h3>Results</h3><div>A total of 255 older adults aged ≥60 years (67.6 % women) were included, with a mean age of 70.8 ± 7.3 years. The prevalence of sarcopenia was 16.9 %. Advanced age (OR = 4.26; 95 % CI: 1.75–10.41; <em>p</em> = 0.001) was significantly associated with sarcopenia. In the fully adjusted model, IL-17 (log-transformed) remained significantly associated with sarcopenia (OR = 1.74; 95 % CI: 1.11–2.74; <em>p</em> = 0.017). Age (OR = 1.10; 95 % CI: 1.03–1.17; <em>p</em> = 0.003) and BMI (OR = 0.69; 95 % CI: 0.60–0.79; <em>p</em> &lt; 0.001) were also associated. IL-6, TNF-α, number of medications, sex, and cognitive score were not statistically significant.</div></div><div><h3>Conclusions</h3><div>Elevated IL-17 levels were associated with higher odds of sarcopenia among older adults. These findings suggest that IL-17 may serve as a potential biomarker for sarcopenia, although further longitudinal studies are needed to elucidate its causal role.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"2 4","pages":"Article 100200"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144907462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Classificating middle-aged and older adults through physiological and functional measures","authors":"Veysel Alcan Ph.D","doi":"10.1016/j.aggp.2025.100212","DOIUrl":"10.1016/j.aggp.2025.100212","url":null,"abstract":"<div><div>Aging affects the functional capacity of individuals by causing gradual changes in metabolic, gait, balance and muscle functions. Identifying these changes between middle-aged (45–64) and older (≥65) adults is critical to understanding the biological and functional effects of aging. This study aims to evaluate the differences between middle-aged and older adults in an objective and scalable manner by analyzing metabolic indicators, gait parameters, balance measurements and muscle functions using machine learning (ML) methods. In this study, 57 high-dimensional variables from the MIDUS dataset including gait parameters (e.g. gait speed, cadence, cycle time), muscle function, balance measurements (e.g. path length, swing area), bone mineral density and bioelectrical impedance spectroscopy markers were used. Supervised ML models were applied to classify the age groups: Partial Least Squares Discriminant Analysis (PLS-DA), Principal Component Analysis-Linear Discriminant Analysis (PCA-LDA), Support Vector Machine (SVM), and k-Nearest Neighbors (k-NN). Venetian blind cross-validation approach was applied to evaluate the model performance. Among the models, SVM showed the highest classification accuracy (87 %) on the training data and 77 % accuracy on the testing data. PLS-DA model achieved 82 % accuracy in training and 86 % in testing. While k-NN model showed 87 % accuracy in training, it dropped to 68 % in testing. In terms of sensitivity and specificity values, SVM showed the best performance (96 % sensitivity, 67 % specificity - training; 86 % sensitivity, 55 % specificity - test), while PLS-DA and PCA-LDA models exhibited similar trends. The results show that walking speed, cadence, and balance measurements provide significant contributions to age group discrimination. These findings highlight the role of neuromuscular and physiological factors in functional decline due to aging, demonstrating the potential of machine learning-based classification in aging research.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"2 4","pages":"Article 100212"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145220127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Restrictions in community-based care services and the effect on family caregivers during the COVID-19 pandemic: A mixed-methods study” [Archives of Gerontology and Geriatrics Plus, Volume 2, Issue 4 (2025), Article 100205]","authors":"Ayumi Honda ,&nbsp;Yin Liu ,&nbsp;Mayo Ono ,&nbsp;Takahiro Nishida ,&nbsp;Tatsuya Tsukigi ,&nbsp;Elizabeth B. Fauth ,&nbsp;Sumihisa Honda","doi":"10.1016/j.aggp.2025.100210","DOIUrl":"10.1016/j.aggp.2025.100210","url":null,"abstract":"","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"2 4","pages":"Article 100210"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145684223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trends in chronic kidney disease-related mortality among older adults in the United States from 1999-2020","authors":"Hamza Ehtesham ,&nbsp;Ahmed Kamal Siddiqi ,&nbsp;Marium Omair Mirza ,&nbsp;Mushtaq Ahmad ,&nbsp;Rija Shakil","doi":"10.1016/j.aggp.2025.100161","DOIUrl":"10.1016/j.aggp.2025.100161","url":null,"abstract":"<div><h3>Background</h3><div>With increasing age in the United States, the disease burden of chronic kidney disease (CKD) has increased. The CKD-related mortality trends have not been explored for individuals aged ≥ 65 years. The aim of the study was to identify and evaluate the trends in sex, race, and region among CKD-related mortality in older adults.</div></div><div><h3>Methods</h3><div>Death records sourced from the CDC WONDER (Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research) database were used to analyze mortality trends of CKD in individuals aged ≥65 years from 1999 to 2020. We computed age-adjusted mortality rates (AAMRs) per 100,000 population and annual percent changes (APC) using Joinpoint software. The analysis was structured according to year, sex, race/ethnicity, and geographical regions.</div></div><div><h3>Results</h3><div>From 1999 to 2020, there were 1,572,057 CKD-related deaths. The age-adjusted mortality rate (AAMR) rose from 1999 to 2005, declined until 2009, surged from 2009 to 2012, fell in 2015, and increased again in 2020. Men had a higher AAMR (225) than women (136.3). Non-Hispanic Black or African Americans experienced the highest AAMR (319.2), followed by NH American Indian or Alaska Native (229.5), Hispanic (178.5), NH white (154.5), and NH Asian or Pacific Islander (144.1). Regionally, AAMR was highest in the Midwest (184.6) and lower in non-metropolitan areas (133.3) compared to metropolitan areas (126.3).</div></div><div><h3>Conclusion</h3><div>CKD-related mortality is rising among U.S. adults ≥ 65, especially in non-Hispanic African American males in the Midwest and rural areas. Screening high-risk individuals can enable early detection and lower mortality rates.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"2 3","pages":"Article 100161"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144090520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}