Archives of Gerontology and Geriatrics Plus最新文献

{"title":"Sex differences in risk factors among Alzheimer's dementia patients with metabolic encephalopathy","authors":"Dami Taiwo Ojo , Philip Xavier Broughton , Adebobola I Nathaniel , Nathan Gerhard Faulstich , James Wayne Patterson , Killian Joseph Bucci , Danny Ngoc Pham , Philip Cole Brewer , Sammy Hilmi Omar , Laurie Roley , Connor John O’Brien , Timi Kehinde Ojo , Emmanuel I Nathaniel , Richard L. Goodwin , Thomas I. Nathaniel","doi":"10.1016/j.aggp.2025.100213","DOIUrl":"10.1016/j.aggp.2025.100213","url":null,"abstract":"<div><h3>Background</h3><div>Differences in risk factors and demographics may explain sex differences in Alzheimer’s dementia patients with metabolic encephalopathy (ADME). This study aims to identify the different risk factors in the population of ADME patients and determine whether these factors differ between male and female ADME patients.</div></div><div><h3>Method</h3><div>Sex differences in risk factors for Alzheimer dementia (AD) were assessed using retrospective data analysis. The univariate analysis was used to determine differences in risk factors for male and female AD patients. Multivariate analysis predicted specific risk factors associated with male and female AD patients.</div></div><div><h3>Results</h3><div>In the adjusted analysis, ADME patients that present with hypertension (OR(odd ratio) = 1.102, 95 % confidence interval(CI), 1.010–1.203, <em>P</em> = 0.029), peripheral vascular disease (od(OR) = 2.075, 95 % CI, 1.769–2.434, <em>P</em> = <0.001), atrial fibrillation (OR = 1.507, 95 % CI, 1.297–1.751, <em>P</em> = <0.001), hallucinations (OR = 2.052, 95 % CI, 1.242–3.390, <em>P</em> = <0.001), thyroid disease (OR = 7.762, 95 % CI, 3.721–16.189, <em>P</em> = <0.001), traumatic head injury (OR = 13.754, 95 % CI, 7.361–25.699, <em>P</em> = <0.001), pneumonia (OR = 1.271, 95 % CI, 1.144–1.413, <em>P</em> = <0.001), and have a history of alcohol use (OR = 1.877, 95 % CI, 1.709–2.061, <em>P</em> = <0.001) were more likely to be males. In contrast, AD patients that present with osteoporosis (OR = 0.317, 95 % CI, 0.266–0.377, <em>P</em> = <0.001), cancer (OR = 0.526, 95 % CI, 0.362–0.765, <em>P</em> = <0.001), anxiety (OR = 0.518, 95 % CI, 0.443–0.605, <em>P</em> = <0.001), urinary tract infection (OR = 0.355, 95 % CI, 0.311–0.404, <em>P</em> = <0.001), upper respiratory infection (OR = 0.061, 95 % CI, 0.033–0.111, <em>P</em> = <0.001), secondary dementia (OR = 0.435, 95 % CI, 0.242–0.781, <em>P</em> = <0.001), gastrointestinal ulceration (OR = 0.07, 95 % CI, 0.025–0.195, <em>P</em> = <0.001), chronic obstructive pulmonary disorder (OR = 0.834, 95 % CI, 0.733–0.949, <em>P</em> = <0.001), treated with SSRI (OR = 0.834, 95 % CI, 0.761–0.915, <em>P</em> = <0.001) including buspirone (OR = 0.624, 95 % CI, 0.546–0.715, <em>P</em> = <0.001) were more likely to be females.</div></div><div><h3>Conclusions</h3><div>In our findings, females were more likely to have osteoporosis, cancer, anxiety, urinary tract infection, upper respiratory infection, secondary dementia, gastrointestinal ulceration, and chronic obstructive pulmonary disorder than males. In contrast, men were more likely to have hypertension, atrial fibrillation, peripheral vascular disorder, hallucination, thyroid diseases, traumatic brain injury, pneumonia, and alcohol abuse than females. The clinical implications of our findings underscore the importance of recognizing sex differences in patients with ADME, as they may provide va","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"2 4","pages":"Article 100213"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145220125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Depression and chronic diseases among older adults: The moderating role of smoking","authors":"Yong Kang Cheah ,&nbsp;Sharifah Nazeera Syed Anera ,&nbsp;Mohd Azahadi Omar ,&nbsp;Noor Hazilah Abd Manaf ,&nbsp;Zera Zuryana Idris","doi":"10.1016/j.aggp.2025.100219","DOIUrl":"10.1016/j.aggp.2025.100219","url":null,"abstract":"<div><div>Depression and chronic diseases often coexist. They possess negative impacts on health outcomes among older adults. The present study explores the associations between depression and chronic diseases, as well as the moderating role of smoking within a large sample of older adults. Cross-sectional data from the Malaysian National Health and Morbidity Survey 2018 were utilised. Probit models were used to assess parameters influencing the probability of experiencing depression. The moderating effect of smoking was examined by adding diabetes-smoking and hypertension-smoking interaction terms to the regression models. Results showed that older adults with diabetes and hypertension were more likely to experience depression compared to their non-diabetic and non-hypertensive counterparts. While smoking was not independently associated with depression, it moderated the relationship between diabetes and depression. However, the hypertension-depression relationship was not moderated by smoking. Other factors that were correlated with depression included gender, ethnicity, marital status, education, income, physical activity and body mass index (BMI). In conclusion, smoking played an important role in strengthening the relationship between depression and diabetes. Anti-depression policies should give particular consideration to diabetic older adults who smoked tobacco. Interventions to reduce the prevalence of depression should also take account of older adults’ demographic traits and lifestyles.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"2 4","pages":"Article 100219"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145319506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Measuring mobile device proficiency: a cross-sectional validation of the shortened japanese version of the mobile device proficiency questionnaire","authors":"Suguru Shimokihara ,&nbsp;Hiroyuki Tanaka ,&nbsp;Walter R. Boot ,&nbsp;Yoshikazu Iwakura ,&nbsp;Arisa Nishitani ,&nbsp;Yuta Tanaka ,&nbsp;Takayuki Tabira","doi":"10.1016/j.aggp.2025.100221","DOIUrl":"10.1016/j.aggp.2025.100221","url":null,"abstract":"<div><h3>Background</h3><div>Mobile devices enhance the independence and quality of life of older adults by supporting communication, information access, and daily functioning. However, many older individuals struggle to effectively use such technologies. Accurate assessment of mobile device proficiency is essential for tailoring support and promoting digital inclusion in the aging population. Although the Japanese version of the Mobile Device Proficiency Questionnaire (MDPQ-J) has demonstrated strong validity, its 46-item format imposes a burden on respondents and limits its utility in field settings.</div></div><div><h3>Objective</h3><div>This study aimed to develop and validate shortened versions of the MDPQ-J using item response theory to provide efficient and psychometrically sound tools for assessing mobile device proficiency in older Japanese adults.</div></div><div><h3>Methods</h3><div>A total of 229 Japanese participants, including 108 older adults (aged &gt;65years), completed the full 46-item MDPQ-J. Rasch analysis and item response theory were applied to evaluate dimensionality, item fit, and local independence.</div></div><div><h3>Results</h3><div>A reduction in the number of items in the MDPQ-J was appropriate, and two shortened versions were developed: MDPQ-J14 for the general population and MDPQ-J20OA for older adults. Items were selected based on model fit, local independence, and discrimination parameters. In MDPQ-J14, “Use video-messaging apps” showed the highest discrimination, whereas in MDPQ-J20OA, “Copy and paste text using the touchscreen” demonstrated the strongest item discrimination.</div></div><div><h3>Conclusions</h3><div>The MDPQ-J14 and MDPQ-J20OA are efficient, valid, and culturally appropriate tools for assessing mobile device proficiency. Their brevity and flexibility make them suitable for wide application in research, education, and gerontechnology interventions in aging societies.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"2 4","pages":"Article 100221"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145320796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Human rights of persons with dementia and their care partners: An exploratory study","authors":"Alexandra Lemay-Compagnat ,&nbsp;Yves Couturier ,&nbsp;Laura Rojas-Rozo ,&nbsp;Pamela Roach ,&nbsp;Megan E. O’Connell ,&nbsp;Carrie McAiney ,&nbsp;Deniz Cetin-Sahin ,&nbsp;Geneviève Arsenault-Lapierre ,&nbsp;Evgeny Neiterman ,&nbsp;Debra Morgan ,&nbsp;Marie-Claude Lafleur ,&nbsp;Diane Dumaresq ,&nbsp;Thérèse Trépanier ,&nbsp;Paul Lea ,&nbsp;Heather Eagleson ,&nbsp;Denis O’Connor ,&nbsp;Jody Peters ,&nbsp;Rosette Fernandez Loughlin ,&nbsp;Mary Beth Wighton ,&nbsp;Isabelle Vedel","doi":"10.1016/j.aggp.2025.100217","DOIUrl":"10.1016/j.aggp.2025.100217","url":null,"abstract":"<div><div>Background: Human rights concerns are well documented in the care for persons living with dementia (PLWDs), who often face isolation, exclusion, abuse, injustice, and marginalization. Aim: This study explored the experiences of PLWDs and their care partners (CPs) with health and social services in Canada during the COVID-19 pandemic, through a human rights lens. Methodology: A qualitative multiple case study using a participatory approach was conducted between April 2022 and April 2023. Semi-structured interviews were held with 11 PLWDs and 55 CPs across Quebec, Ontario, Saskatchewan, and Alberta. Guided by the World Health Organization Framework on human-rights for PLWDs, a hybrid thematic analysis was conducted within each province, followed by cross-provincial synthesis. Results: Four major themes were identified: (1) Health and social care professionals’ practices and behaviors; (2) Care partners’ role and burden; (3) Unpreparedness of the healthcare system; (4) Public health measures. Conclusion: PLWDs experienced widespread rights violations, largely due to the cognitive nature of the illness. Despite regional differences, a shared experience of rights infringement was evident. Findings underscore the need for meaningful involvement of PLWDs and CPs in care decisions, accessible rights education, and sustained access to services. Tailored policies must address the needs of PLWDs and CPs, and decision-makers should carefully weigh the risks and benefits of allowing CPs into care facilities.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"2 4","pages":"Article 100217"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145320798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longitudinal relationships between persistent moderate-to-severe pain and poor multidimensional sleep health with frailty among community-dwelling older adults","authors":"Tuo-Yu Chen ,&nbsp;Kai-Wen Hsu ,&nbsp;Feng-Jen Tsai ,&nbsp;Chyi-Huey Bai ,&nbsp;Hui-Chuan Hsu ,&nbsp;Yi-Hua Chen ,&nbsp;Yi-Chun Kuan","doi":"10.1016/j.aggp.2025.100224","DOIUrl":"10.1016/j.aggp.2025.100224","url":null,"abstract":"<div><div>Evidence supports that persistent pain, poor multidimensional sleep health, and frailty might be related among community-dwelling older adults. However, the associations of persistent pain and poor multidimensional sleep health with frailty are not yet fully understood, and it remains unclear whether better sleep could alleviate the impact of persistent pain on frailty. We investigated whether baseline persistent moderate-to-severe pain and poor multidimensional sleep health predicted frailty at 4-year follow-up among community-dwelling older adults and whether the relationship between persistent moderate-to-severe pain and frailty differed by multidimensional sleep health status. Data were from the Taiwan Longitudinal Study on Aging (<em>N</em> = 2490; 2011–2015). A frailty index based on the deficit accumulation model was built. Pain included four categories (no pain [reference], some pain, acute moderate-to-severe pain, and persistent moderate-to-severe pain). Multidimensional sleep health was assessed using the SATED model. Covariates included sociodemographic characteristics, health status, and health behaviors. The results showed that acute and persistent moderate-to-severe pain and poor multidimensional sleep health increased the risks of frailty at 4-year follow-up. A significant interaction effect was observed between persistent moderate-to-severe pain and poor multidimensional sleep health. Specifically, frailty risks exhibited a dose-response relationship with poor sleep health. Compared to no pain, poor multidimensional sleep health elevated already heightened risks of frailty by persistent moderate-to-severe pain. Our findings revealed that acute and persistent moderate-to-sever pain and poor multidimensional sleep health were important factors for future frailty. Improving multidimensional sleep health among community-dwelling older adults with persistent moderate-to-sever pain may help mitigate the risks of frailty.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"2 4","pages":"Article 100224"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145519581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Additive and interactive effects of social, financial and environmental factors on gait speed among community dwelling older adults in Nigeria: A cross-sectional study","authors":"Francis Kolawole ,&nbsp;Osakpolor V Oni ,&nbsp;Ejehi Omoighe ,&nbsp;Israel Adandom ,&nbsp;Daniel Rayner ,&nbsp;Henrietta Fawole ,&nbsp;Michael Kalu","doi":"10.1016/j.aggp.2025.100225","DOIUrl":"10.1016/j.aggp.2025.100225","url":null,"abstract":"<div><h3>Objectives</h3><div>Gait speed is considered the sixth vital sign in geriatric care, due to its predictive role in health and social outcomes. Although various factors influence gait speed, environmental and social factors are frequently overlooked, particularly in developed regions with distinct cultural perspectives. The study examines how these environmental, financial and social factors additively or interactively influence gait speed of community dwelling older adults in Nigeria.</div></div><div><h3>Method</h3><div>We employed a cross-sectional study design included 408 community-dwelling older adults (mean [S.D] = 68.0(6.6) years) from a city in Nigeria. We administer validated measures to assess nine neighborhood environmental factors, five social factors and self-reported income. Gait Speed was assessed using the 10-metre walk test and categorized &lt; 0.8m/s (slow speed) and ≥0.8m/s (normal). Logistic regression analysis was used to determine the predictors of gait speed in this dichotomized form.</div></div><div><h3>Results</h3><div>Slow gait speed prevalence was 72.4 %. The additive model revealed that age (OR = 0.798, <em>p</em> &lt; 0.001), social network (OR = 1.079, <em>p</em> &lt; 0.01), and neighborhood surroundings (OR = 1.117, <em>p</em> &lt; 0.01) were significant predictors of high gait speed. In the interaction model, age, social network, and neighborhood surroundings remained significant predictors and education level became significant: secondary education (OR = 3.986, <em>p</em> = 0.047) and tertiary education (OR = 4.580, <em>p</em> = 0.038) associated with higher odds of high gait speed.</div></div><div><h3>Discussion</h3><div>Findings suggest that enhancing social networks and improving neighborhood environments may be crucial in promoting better mobility outcomes, particularly among diverse older adults.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"2 4","pages":"Article 100225"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145571448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Examining rural-urban differences in pain-depression comorbidity and its association with elder abuse: Multivariable decomposition analysis of nationally representative cross-sectional survey","authors":"Hemant Singh Gurjar ,&nbsp;Anita Mehta","doi":"10.1016/j.aggp.2025.100204","DOIUrl":"10.1016/j.aggp.2025.100204","url":null,"abstract":"<div><h3>Background</h3><div>This study investigates rural–urban differences in Pain-Depression Comorbidity (PDC) and its association with elder abuse among older adults in India. It aims to identify the socio-demographic, functional and behavioural health predictors contributing to PDC and elder abuse.</div></div><div><h3>Data and methods</h3><div>Data were drawn from LASI, 2017–18 survey, comprising 30,772 individuals aged 60+. Pain, depressive symptoms (CES-D-10) and elder abuse were defined based on self-reported data. Covariates on socio-demographic, functional and behavioural health were included. Descriptive statistics, chi-square tests, nested-multilevel logistic-regression models and multivariable-decomposition analysis were used to quantify rural–urban disparities in PDC.</div></div><div><h3>Results</h3><div>The prevalence of PDC was higher among rural older adults (15 %) compared to their urban counterparts (11 %). A significant association between elder abuse and PDC was observed in both rural and urban areas. The odds of experiencing PDC were significantly higher among individuals reporting elder abuse, with a stronger association in urban areas (AOR = 2.53) than in rural areas (AOR = 1.78). Decomposition analysis shows that 66 % of the rural–urban gap in PDC was attributed to differences in observed characteristics, particularly education, caste, functional health, living arrangement and elder abuse.</div></div><div><h3>Conclusion</h3><div>This study offers important insights into the interrelationship between elder abuse and PDC in India, revealing substantial rural–urban disparities. The findings highlight the urgent need for residence-specific public health strategies to address the dual burden of pain and depression among older adults. Targeted interventions, especially in rural areas, should focus on education, functional-health and the prevention of elder abuse.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"2 4","pages":"Article 100204"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145010353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The multifactorial nature of Alzheimer’s disease: A review of diverse determinants and the essential role of multimodal machine learning","authors":"Hesameddin Mostaghimi ,&nbsp;Daniel A. Cohen ,&nbsp;Hamid. R. Okhravi ,&nbsp;Bahar Niknejad ,&nbsp;Michel A. Audette","doi":"10.1016/j.aggp.2025.100207","DOIUrl":"10.1016/j.aggp.2025.100207","url":null,"abstract":"<div><div>Alzheimer’s disease (AD), the most prevalent form of dementia, arises from a complex interplay of determinants, including neurological and cognitive impairments, molecular and genetic markers, systemic comorbidities, and lifestyle-related factors. While traditional research has often focused on individual or narrow sets of determinants, recent advancements highlight the necessity of examining these diverse contributors in unison. In addition, the rapid growth of heterogeneous multimodal data in healthcare necessitates sophisticated analytical frameworks. In this review, we first summarize the evidence on the broad spectrum of AD risk factors and mechanisms, and then discuss the necessity and potential of multimodal machine learning (ML) techniques in integrating complex datasets, which could ultimately lead to personalized therapeutic strategies for this disease. This narrative review qualitatively synthesizes 250 peer-reviewed studies published between 2010 and 2024.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"2 4","pages":"Article 100207"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145220126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of single and dual sensory impairments on cognitive function and psychological well-being among older adults in Upper Egypt","authors":"Rasha Ahmed Fouad ,&nbsp;Esteer Ibrahim Ghayth ,&nbsp;Safaa Mostafa Abdeen ,&nbsp;Sanaa Mostafa Khalifa","doi":"10.1016/j.aggp.2025.100209","DOIUrl":"10.1016/j.aggp.2025.100209","url":null,"abstract":"<div><h3>Background</h3><div>Dual sensory impairment (DSI), involving both vision and hearing loss, is increasingly recognized as a significant contributor to poor psychological health and cognitive decline in older adults. However, evidence from resource-limited settings, such as Upper Egypt, remains scarce.</div></div><div><h3>Objectives</h3><div>This study aimed to examine the associations between single and dual sensory impairments and cognitive function, depression, anxiety, and loneliness among community-dwelling older adults in Upper Egypt.</div></div><div><h3>Methods</h3><div>A descriptive cross-sectional study was conducted with 100 adults aged ≥60 years attending ophthalmology and audiology clinics at Sohag University Hospital. Validated tools were used to assess depression (Geriatric Depression Scale-15, GDS-15), anxiety (Generalized Anxiety Disorder-7, GAD-7), loneliness (University of California, Los Angeles Loneliness Scale, UCLA-LS), and cognitive function (Mini-Mental State Examination, MMSE). Data were analyzed using descriptive statistics, ANOVA, independent <em>t</em>-tests, and Pearson correlation coefficients.</div></div><div><h3>Results</h3><div>Among participants, 52 % had vision impairment, 21 % had hearing impairment, and 27 % reported dual sensory loss. A high prevalence of adverse psychological and cognitive outcomes was observed: 81.3 % reported moderate to severe depression, 89 % mild to moderate anxiety, 49 % high loneliness, and 80 % cognitive impairment. Dual sensory impairment was significantly associated with worse psychological outcomes (p&lt;.001), but no significant differences in cognitive scores were found across sensory impairment types.</div></div><div><h3>Conclusions</h3><div>Dual sensory loss is strongly associated with increased depression, anxiety, and loneliness among older adults in Upper Egypt. These findings underscore the critical need for integrated screening and targeted intervention strategies within geriatric care, especially in underserved regions like Upper Egypt, to improve the well-being of this vulnerable population.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"2 4","pages":"Article 100209"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145220123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analyzing COVID-19 fall occurrences amongst older adult populations","authors":"Aman Sandhu ,&nbsp;Benjamin Millar ,&nbsp;Faith Kean ,&nbsp;Leah Pasch ,&nbsp;Rhea Verma ,&nbsp;Junchao Shen ,&nbsp;Nancy Nagib ,&nbsp;Rahul Kashyap","doi":"10.1016/j.aggp.2025.100228","DOIUrl":"10.1016/j.aggp.2025.100228","url":null,"abstract":"<div><h3>Introduction</h3><div>The COVID-19 pandemic has been associated with increased health risks among elderly populations, who were often isolated and led more sedentary lifestyles. Prior studies on fall risks during the pandemic show variable results. This systematic review examines trends in elderly fall rates after the onset of COVID-19.</div></div><div><h3>Materials/Methods</h3><div>PubMed and Embase were the primary databases used and screened via Rayyan Software. Reviewers independently screened articles with blinding enabled. Synonyms of “COVID-19,” “elderly,” and “fall rate” were used. Eligible studies were in English, focused on individuals aged &gt;65, and included falls from level height. Studies required two data collection periods: one before and one after March 2020, with sample sizes and fall incidences reported. Recreational or accidental falls were excluded. The review was registered on PROSPERO (CRD42023418490).</div></div><div><h3>Results</h3><div>Of 913 articles, 6 met inclusion criteria, with a total of 27,055 patients. Pooled analysis showed increased odds of falls during the pandemic (OR=1.17, 95 % CI: 1.11–1.24, <em>p</em> &lt; 0.00001). The difference in fall rates was statistically significant. Heterogeneity was high (I² = 88 %). Sensitivity analysis excluding the highest-weight article showed OR = 1.08 (95 % CI: 1.02–1.15, <em>p</em> = 0.0001), with I² = 85 %. Notable comorbidities included diabetes and hypertension.</div></div><div><h3>Conclusion</h3><div>This review highlights a statistically significant increase in elderly fall rates during the COVID-19 pandemic. Despite heterogeneity and comorbid risks, an upward trend in fall rates was evident, underscoring the need for improved at-home interventions and preventive strategies during public health crises.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"2 4","pages":"Article 100228"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145571449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}