Archives of Gerontology and Geriatrics Plus最新文献

{"title":"Mapping knowledge landscapes and emerging trends in digital biomarkers for dementia in older adults: A scoping and bibliometric analysis","authors":"Azliyana Azizan ,&nbsp;Shihua Cao ,&nbsp;Akehsan Dahlan ,&nbsp;Susi Endrini","doi":"10.1016/j.aggp.2025.100148","DOIUrl":"10.1016/j.aggp.2025.100148","url":null,"abstract":"<div><div>This paper presents a systematic bibliometric analysis of the research landscape at the intersection of Alzheimer's disease and gerontechnology, identifying key contributors, research hotspots, and emerging trends. Utilizing data from Scopus and Web of Science, the study applies tools such as VOSviewer and ScientoPy to analyze co-authorship networks, keyword occurrences, and citation trends. The results reveal growing contributions from global regions, particularly the U.S., Italy, and China, with increasing emphasis on assistive technologies and artificial intelligence for early diagnosis. However, significant gaps exist, especially in studies addressing long-term effectiveness and inclusivity across demographic groups. This landscape analysis provides crucial insights to guide future research on integrating technology into Alzheimer's care, underscoring the importance of a patient-centered approach for sustainable solutions.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"2 2","pages":"Article 100148"},"PeriodicalIF":0.0,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143807002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Positive spousal interactions as a mediator between perceived neighborhood disorder and depressive symptoms among married/partnered adults","authors":"Seungjong Cho ,&nbsp;Aloen L. Townsend","doi":"10.1016/j.aggp.2025.100160","DOIUrl":"10.1016/j.aggp.2025.100160","url":null,"abstract":"<div><h3>Purpose</h3><div>This cross-sectional study aimed to test the mediating role of positive spousal interactions linking perceived neighborhood disorder and depressive symptoms and whether this model varied by gender.</div></div><div><h3>Materials and Methods</h3><div>The current study analyzed 2008 married/partnered adults ages 50 and older from the 2018 Health and Retirement Study (<em>n</em> = 1059 females and <em>n</em> = 949 males) using a full-information maximum likelihood structural equation model. Perceived neighborhood disorder was measured as a composite score of physical and social disorder, while depressive symptoms were assessed using the CES-D8 scale. The sample had a mean age of 66.7 years.</div></div><div><h3>Results</h3><div>Higher perceived neighborhood disorder was related to lower positive spousal interactions and higher depressive symptoms for both males and females. Lower positive spousal interactions were also associated with higher depressive symptoms for both genders. This study identified a significant mediation effect whereby one path through which perceived neighborhood disorder adversely affects depressive symptoms is through lower positive spousal interactions. This mediation effect was significant for both males and females.</div></div><div><h3>Discussion</h3><div>Results supported the mediating role of spousal support as a vulnerable psychosocial resource in the stress process theory. Implications for improving depressive symptoms in midlife and older adults living in stressful neighborhoods are discussed.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"2 2","pages":"Article 100160"},"PeriodicalIF":0.0,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143807003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of absence of subjective memory complaints on characteristics of meaningful occupations in community-dwelling older people","authors":"Katsushi Yokoi ,&nbsp;Nobuyuki Miyai ,&nbsp;Yukiko Sougawa ,&nbsp;Sonomi Hattori ,&nbsp;Miyoko Utsumi ,&nbsp;Megumi Nakamura ,&nbsp;Mikio Arita","doi":"10.1016/j.aggp.2025.100158","DOIUrl":"10.1016/j.aggp.2025.100158","url":null,"abstract":"<div><h3>Background</h3><div>Subjective memory complaints increase with age, leading to limitations in daily life. Subjective memory complaints should be considered from the perspective of occupations closely related to daily life. This study investigated the association between the absence of subjective memory complaints and characteristics of meaningful occupations. In this study, occupation is defined not only as work but, more broadly, as important activities individuals perform.</div></div><div><h3>Study design</h3><div>A community-based cross-sectional study.</div></div><div><h3>Methods</h3><div>This study included 259 community-dwelling older people (aged 73.9 ± 5.8 years, 100 males and 159 females) with Mini-Mental State Examination-Japanese scores ≥25. Subjective memory complaints were assessed using a question from the Centers for Disease Control and Prevention. Questionnaires on meaningful occupations (number, frequency, continuation, performance, and satisfaction) were administered. Logistic regression analysis was performed to examine the association between the absence of subjective memory complaints and occupational characteristics, adjusting for age, education, body mass index, alcohol consumption, smoking status, and disease status as covariates.</div></div><div><h3>Results</h3><div>Of the 259 participants, 131 (50.6 %) had no subjective memory complaints. Occupational performance was associated with the absence of subjective memory complaints, with an adjusted odds ratio of 1.53 (95 %CI = 0.99–2.36) for males. Occupational satisfaction was significantly associated with the absence of subjective memory complaints, with an adjusted odds ratio of 1.39 (95 %CI = 1.02–1.90) for females.</div></div><div><h3>Conclusion</h3><div>The absence of SMCs appears to be associated with positive subjective occupational performance and satisfaction; however, further research, including an exploration of gender differences and potential associations, is needed.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"2 2","pages":"Article 100158"},"PeriodicalIF":0.0,"publicationDate":"2025-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143807004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-communicable diseases and risk factors profiling among geriatric population residing in Hyderabad city, India","authors":"Karthikeyan Ramanujam,&nbsp;Joyeeta Thakur,&nbsp;Rajitha Triveni Koralla,&nbsp;JJ Babu Geddam,&nbsp;Samarasimha Reddy N","doi":"10.1016/j.aggp.2025.100153","DOIUrl":"10.1016/j.aggp.2025.100153","url":null,"abstract":"<div><h3>Background</h3><div>India's aging population, expected to reach 340 million by 2050, faces a growing burden of non-communicable diseases (NCDs) like hypertension, diabetes, and obesity.</div></div><div><h3>Objective</h3><div>In this study, we assessed the prevalence of Non communicable diseases among the elderly population residing in Hyderabad city in India and identified the associated risk factors.</div></div><div><h3>Methods</h3><div>We conducted a community-based cross-sectional study in an urban locality of Hyderabad city, Telangana state among 1320 elderly individuals aged 60 years and above. Data on anthropometric measurements, dietary intakes, socio-economic factors, and NCD history were collected using structured questionnaires and standardized tools. We have used descriptive statistics to estimate the burden of NCDs and a multivariable logistic regression was used for identifying the associated risk factors.</div></div><div><h3>Results</h3><div>We observed that among elderly population, 49.9% (95% CI 47.2%-52.6%) had reported hypertension, 25.8% (95% CI 23.5%-28.3%) had diabetes, and 44.3% (41%-47.5%) were obese, with women having notably higher burden for all three conditions. Dietary patterns showed moderate diversity, with only 41.2% elderly population consuming protein-rich foods weekly followed by 74.4% consuming vegetables. Multivariable analysis revealed that individuals with obesity had increased odds of hypertension (AOR 2.59; 95% CI 1.83–3.66) and diabetes (1.65; 95% CI 1.03–2.63) compared to individuals without obesity. The participants with abnormal waist hip ratio were at higher odds of having hypertension (AOR 1.66; 95% CI; 1.03–2.67).</div></div><div><h3>Conclusion</h3><div>Our findings highlight the significant burden of NCDs among urban elderly, driven by obesity and suboptimal dietary patterns. Public health policies should prioritize focusing on balanced nutrition for control of NCDs among elderly population.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"2 2","pages":"Article 100153"},"PeriodicalIF":0.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143791139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of commitment to values on family caregivers’ depression: Examination of the stress process model","authors":"Koji Abe,&nbsp;Shiho Nagano","doi":"10.1016/j.aggp.2025.100152","DOIUrl":"10.1016/j.aggp.2025.100152","url":null,"abstract":"<div><h3>Objectives</h3><div>This study aims to focus on personal values, a key component of acceptance and commitment therapy (ACT), and to examine their role in the stress process model of famil caregivers.</div></div><div><h3>Methods</h3><div>A screening survey of 6000 people aged 65 years and older was conducted, and data from 247 family caregivers who met the inclusion criteria were analyzed. The hypothesis model included the cognitive and daily functioning of individuals with dementia, behavioral and psychological symptoms of dementia, caregivers’ personal values, and depression.</div></div><div><h3>Results</h3><div>Structural equation modeling showed that the stress process model of caregivers with personal values fit the data very well. Both aspects of caregiver behavior, progress and obstruction toward acting in accordance with personal values, significantly affected caregiver depression.</div></div><div><h3>Conclusions</h3><div>One of the main components of ACT, progressive and obstructive behaviors toward personal values, was significantly associated with family caregiver depression. The personal values of family caregivers are important for maintaining their mental health.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"2 2","pages":"Article 100152"},"PeriodicalIF":0.0,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143776465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between changes in activities to prevent disability due to the COVID-19 pandemic and mental status or life-related functions among community-dwelling older adults","authors":"Keita Nakagawa ,&nbsp;Hungu Jung ,&nbsp;Hitoshi Okamura ,&nbsp;Tomoyuki Ishii ,&nbsp;Shinya Ishii","doi":"10.1016/j.aggp.2025.100143","DOIUrl":"10.1016/j.aggp.2025.100143","url":null,"abstract":"<div><h3>Background</h3><div>Disability prevention is important for older adults and the society at large. Despite its relevance, factors associated with changes in disability prevention activities due to the COVID-19 pandemic remain unclear. This study aimed to investigate the extent to which the implementation of disability prevention activities has changed due to the COVID-19 pandemic among community-dwelling older adults, and to examine the relationship between these changes and mental status or life-related functions.</div></div><div><h3>Methods</h3><div>This cross-sectional study used self-report questionnaires with a random sample of older adults in 10 locations. The mailing area was determined based on the regional characteristics and demographic changes. Participants were categorized into two groups: those who maintained their disability prevention activities and those who decreased such activities before and after the COVID-19 pandemic. Mental status and life-related functions were investigated using the Kihon Checklist.</div></div><div><h3>Results</h3><div>Of the 263 participants included in the analysis, 89 (33.8 %) decreased their disability prevention activities before and after the COVID-19 pandemic. Factors associated with a decrease in disability prevention activities were identified as those with a higher number of depressive items on the Kihon Checklist (aOR = 0.788, 95 % CI: 0.637–0.947, <em>p</em> = 0.027) and those with a higher total number of disability prevention activities before the COVID-19 pandemic (aOR = 0.653, 95 % CI: 0.476–0.896, <em>p</em> = 0.008).</div></div><div><h3>Conclusion</h3><div>These findings suggest the characteristics of older adults that require special attention when taking steps to support the continuation of disability prevention activities in future events such as the COVID-19 pandemic.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"2 2","pages":"Article 100143"},"PeriodicalIF":0.0,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143726152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does poverty increase geriatric depressive symptoms in older adults in Turkey? The mediating role of quality of life","authors":"Ecem Çakın,&nbsp;Taner Artan,&nbsp;Rumeysa Dinçer,&nbsp;Ahmed Taha Arifoglu","doi":"10.1016/j.aggp.2025.100147","DOIUrl":"10.1016/j.aggp.2025.100147","url":null,"abstract":"<div><div>The generalization of factors associated with the mental health of older adults remains a subject of debate in the literature. This study aims to examine the relationship between poverty and quality of life on geriatric depression symptoms among older adults in Turkey within the framework of an inter-factorial analysis model. The sample consists of 417 older adults residing in Turkey (<em>M</em> = 69.4, SD = 7.43). The findings indicate that poverty is negatively associated with quality of life and positively associated with geriatric depression symptoms. Additionally, quality of life is negatively associated with geriatric depression symptoms. Moreover, the study reveals that quality of life has a partial and negative mediating role in the relationship between poverty and geriatric depression symptoms. In other words, quality of life acts as a protective factor in the relationship between poverty and geriatric depression symptoms. Based on these results, several recommendations are proposed to enhance the quality of life of older adults living in poverty.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"2 2","pages":"Article 100147"},"PeriodicalIF":0.0,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143726151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Blood biomarkers associated with all-cause mortality risk: Accessibility and clinical utility for lifestyle medicine","authors":"Matthew Halma ,&nbsp;Mariyam Aniwar ,&nbsp;Edgar Selem ,&nbsp;Jack Tuszynski ,&nbsp;Joseph Varon ,&nbsp;Paul Marik","doi":"10.1016/j.aggp.2025.100145","DOIUrl":"10.1016/j.aggp.2025.100145","url":null,"abstract":"<div><div>Mortality associated biomarkers are advantageous in that they are strongly associated with general health. Disease specific biomarkers, if optimized for, can often create suboptimal outcomes in another area, thereby compromising the health of the measured person. We use an existing database of mortality associated blood biomarkers to assess their applicability as part of a general anti-aging protocol, and the cost effectiveness of a strategy relying on biomarker testing combined with targeted interventions to improve one's aging outlook. Early intervention for suboptimal biomarkers may yield health benefits in later age, and biomarker tests provide a means of intervening in negative health habits and promoting healthy behavior.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"2 2","pages":"Article 100145"},"PeriodicalIF":0.0,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143697958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aging through the lens of the gut microbiome: Challenges and therapeutic opportunities","authors":"Kanimozhi N V,&nbsp;Sukumar M","doi":"10.1016/j.aggp.2025.100142","DOIUrl":"10.1016/j.aggp.2025.100142","url":null,"abstract":"<div><div>Aging is a complex biological process influenced by genetic, environmental, and lifestyle factors. Among these, the gut microbiome plays a crucial role in modulating health and disease across the lifespan. This review explores the dynamic relationship between aging and the gut microbiome, highlighting its implications for age-related diseases. As individuals age, the gut microbiome undergoes significant compositional and functional changes, often leading to dysbiosis—an imbalance associated with increased inflammation, weakened immunity, and metabolic disorders. The phenomenon of inflammaging, characterized by chronic low-grade inflammation, is closely linked to gut microbial alterations and contributes to neurodegenerative diseases, cardiovascular conditions, and metabolic disorders such as obesity and diabetes. Additionally, the gut-brain axis is emerging as a critical pathway in neurocognitive aging, with microbial metabolites influencing brain function and neuroprotection.</div><div>Given these insights, targeted interventions such as probiotics, prebiotics, and fecal microbiota transplantation (FMT) are being explored as potential strategies to restore microbial balance and improve health outcomes in the elderly. Diet, antibiotics, and medication use also play pivotal roles in shaping gut microbiota composition, further influencing longevity and disease susceptibility. This review synthesizes current research on the aging gut microbiome and discusses therapeutic advancements aimed at mitigating age-related diseases through microbiome-based strategies. Finally, we provide a perspective on future directions in microbiome research, emphasizing its potential in precision medicine for aging populations. Understanding the gut microbiome's role in aging offers novel opportunities for promoting longevity and enhancing quality of life in older adults.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"2 2","pages":"Article 100142"},"PeriodicalIF":0.0,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143683606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Traumatic stress in caregivers of adult patients with cancer: A scoping review","authors":"Elizaveta Klekovkina ,&nbsp;Maya A. Stern ,&nbsp;Carmine Malfitano ,&nbsp;Esme Fuller-Thomson","doi":"10.1016/j.aggp.2025.100141","DOIUrl":"10.1016/j.aggp.2025.100141","url":null,"abstract":"<div><h3>Objective</h3><div>The goal of this review was to critically review the research literature on traumatic stress in caregivers of adult cancer patients. Objectives included identifying the prevalence of significant traumatic stress symptoms, themes within the literature, and factors that are associated with traumatic stress in this population.</div></div><div><h3>Methods</h3><div>A search was conducted of APA PsycInfo, MEDLINE, Embase, and CINAHL. Two authors screened abstracts and full-texts and extracted data from included articles. A total of 1,150 unique titles and abstracts were identified, with 2f articles selected for full-text screening after title and abstract screening. There were 23 studies which were included in the review.</div></div><div><h3>Results</h3><div>Most studies reported a prevalence of PTSD of 15 % and above. The caregivers of newly diagnosed patients, those with recurrent cancer, and those on active treatment were the most distressed. Caregivers of patients who had completed treatment and those of longer-term survivors were less distressed. Significant associations were identified between caregiver traumatic stress and caregiver and patient psychological comorbidity, lower social support, higher caregiver burden, and patient's greater physical symptoms.</div></div><div><h3>Conclusion</h3><div>This scoping review reveals that a substantial proportion of caregivers of adult patients with cancer experience traumatic stress. However, the majority of published studies are cross-sectional, with small sample sizes, and a lack of racial and gender diversity. There is an urgent need for further research, including on proactive and tailored interventions provided at the time of diagnosis or recurrence of the disease.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"2 2","pages":"Article 100141"},"PeriodicalIF":0.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}