Archives of Gerontology and Geriatrics Plus最新文献

{"title":"The association between cognitive leisure activities, mobility, participation and physical activities among community-dwelling older adults in Nigeria","authors":"Sochima Johnmark Obiekwe,&nbsp;Favour Chidera Kanu,&nbsp;Marvelous Oyinloluwa Adeniyi,&nbsp;Chisom Jennifer Chima,&nbsp;Uzoamaka Nwakaego Akobundu,&nbsp;Uchenna Prosper Okonkwo","doi":"10.1016/j.aggp.2026.100257","DOIUrl":"10.1016/j.aggp.2026.100257","url":null,"abstract":"<div><h3>Introduction</h3><div>Cognitive leisure activities are known to improve cognition, executive function, and quality of life, yet their influence on mobility, physical activity, and social participation among older adults is underexplored. This study examined these associations in community-dwelling older adults in Nigeria.</div></div><div><h3>Methods</h3><div>A cross-sectional survey was conducted with 220 (mean age: 70.4 ± 7.36 years) consecutively recruited older adults in Nnewi, using the modified Cognitive Leisure Activities Scale (CLAS), Life-Space Questionnaire (LSQ), Physical Activity Scale for the Elderly (PASE), and the Participation Scale (P-Scale).</div></div><div><h3>Results</h3><div>Over 70% of participants reported never playing chess, checkers, scrabble, or puzzles, while nearly half read books regularly and two-thirds socialised with friends at least monthly. Religious activities were highly prominent, with 90.4% participating weekly or more, while volunteering and club activities were also common. In contrast, creative pursuits such as painting, writing, and attending theatre, concerts, or museums were rare. Listening to music, singing, and watching television showed more balanced distributions across weekly and daily frequencies. The mean physical activity score (PASE) was 139.19 (SD = 60.65), and most participants reported no-to-mild participation restrictions with good levels of mobility. Correlation and regression analyses revealed that cognitive leisure activities were strongly associated with higher life-space mobility and lower participation restrictions, but not with physical activity.</div></div><div><h3>Conclusion</h3><div>Greater engagement in cognitive leisure activities can influence higher life-space mobility and lower participation restrictions, but their influence may be limited or indirect on physical activity; therefore, they should not be sidelined in promoting healthy ageing among community-dwelling older adults.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"3 1","pages":"Article 100257"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147384792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A review on Centella asiatica (L.) nutrient and phytochemical composition and its potential neuroprotective effect in Alzheimer’s disease","authors":"Vinoth Kumar Ganesan ,&nbsp;Rallapalli Rajyalakshmi ,&nbsp;Kumaraswamy Dabburu ,&nbsp;Dharani Abirama Sundari Shanmugam ,&nbsp;Ashwini Devi Balaraman","doi":"10.1016/j.aggp.2025.100237","DOIUrl":"10.1016/j.aggp.2025.100237","url":null,"abstract":"<div><h3>Background</h3><div>Alzheimer's disease (AD) is a gradually developing neurodegenerative disease that affects 47 million individuals globally and is the leading cause of mortality. The disease's pathophysiology is complicated, and several hypotheses have been proposed to explain it, including the amyloid cascade hypothesis, tau hypothesis, cholinergic hypothesis, and oxidative stress hypothesis, all of which involve various biochemical processes. <em>Centella asiatica</em> (<em>L</em>.) has been used as a medicinal herb for thousands of years in India, China, Sri Lanka, Nepal, and Madagascar. <em>Centella asiatica (L.)</em> is one of the chief herbs for treating skin problems, to heal wounds, for revitalising the nerves and brain cells, hence primarily known as a \"Brain Tonic\" in India.</div></div><div><h3>Methods</h3><div>Using the internet databases Science Direct, Web of Science, Scopus, PubMed, and Google Scholar, the neuroprotective effect of <em>Centella asiatica (L.)</em> was searched. The literature review revealed that <em>Centella asiatica (L.)</em> has been shown to exert broad neuroprotective effects through various mechanisms, including enzyme inhibition, preventing the development of amyloid plaques in AD, reducing dopamine neurotoxicity in Parkinson's disease (PD), and reducing oxidative stress.</div></div><div><h3>Result</h3><div>It is possible to argue that <em>Centella asiatica (L.)</em> is a sought after phytopharmaceutical with neuroprotective effects, derived from traditional medicine.</div></div><div><h3>Conclusion</h3><div><em>Centella asiatica (L.)</em> is a widely consumed green vegetable in many countries; incorporating it as a functional food into a regular diet is a practical approach to reap its many health advantages and nutritional profile. Taking advantage of this plant's medicinal, nutraceutical, and nutritional properties would be a significant contribution to holistic healthy ageing.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"3 1","pages":"Article 100237"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145840230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Age, gender and psychological well-being in older students: A study on continuing education and active aging","authors":"Pablo Rosser ,&nbsp;Seila Soler","doi":"10.1016/j.aggp.2026.100250","DOIUrl":"10.1016/j.aggp.2026.100250","url":null,"abstract":"<div><h3>Introduction</h3><div>This study examined how age and gender relate to multiple indicators of psychological well-being among adults enrolled in university continuing-education programmes, to inform more inclusive learning designs for ageing populations.</div></div><div><h3>Methods</h3><div>A quantitative, descriptive–correlational pilot study was conducted with 60 adult learners enrolled in the University Programme for Older Adults at the University of Alicante. Data were collected using a 41-item questionnaire based on Ryff’s Psychological Well-Being framework and analysed using descriptive statistics, independent-samples <em>t</em>-tests, one-way ANOVA, and non-parametric correlations (Kendall’s Tau-b and Spearman’s Rho) when distributional assumptions were not met.</div></div><div><h3>Results</h3><div>Participants were mainly aged 66–75 years (53.3%) and were predominantly women (60%). Statistically significant gender differences emerged in seven well-being items, and age-group differences were observed in ten items related to social support, loneliness, life satisfaction, stress management, and openness to change. Older age tended to be associated with higher life-satisfaction indicators and lower openness to new experiences.</div></div><div><h3>Discussion</h3><div>Results support the need to tailor lifelong-learning programmes to the psychosocial profiles of adult learners, with attention to gendered patterns and age-related changes. Targeted strategies to enhance social connection, autonomy, and meaningful engagement may strengthen well-being and participation in later-life learning.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"3 1","pages":"Article 100250"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146077526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations between sleep patterns and depressive symptoms across disability types in Chinese middle-aged and older adults","authors":"JING LI PHD","doi":"10.1016/j.aggp.2026.100256","DOIUrl":"10.1016/j.aggp.2026.100256","url":null,"abstract":"<div><h3>Background</h3><div>Depression prevalence among elderly individuals with disabilities significantly exceeds that in the general population; however, sleep-depression associations across disability types remain poorly understood. This study examined associations between sleep patterns and depressive symptoms across disability types in Chinese middle-aged and older adults.</div></div><div><h3>Methods</h3><div>This study utilized data from the 2018 China Health and Retirement Longitudinal Study (CHARLS), collecting demographic information, health status, and sleep patterns of participants. We included 1997 participants aged ≥45 years with disabilities categorized into five types: physical, cognitive, visual, hearing, and multiple disabilities. Depressive symptoms were assessed using the CES-<span>d</span>-10 scale, with scores ≥10 indicating depressive symptoms. Multivariable logistic regression and restricted cubic splines were used to examine associations between sleep patterns and depressive symptoms across disability types.</div></div><div><h3>Results</h3><div>The overall prevalence of depressive symptoms was 52.63%, with the highest rate in participants with multiple disabilities (64.09%). Compared with short sleep, normal sleep (6–8 h) reduced depression risk by 30–65% across all disability types. The strongest protective association was observed in visual impairment (OR=0.35, 95% CI: 0.22–0.55). Napping associations varied by disability type. Long napping (&gt;90 min) was associated with a 62% lower risk of cognitive impairment (OR=0.38, 95% CI: 0.18–0.81), while short napping (&lt;30 min) was associated with a threefold higher risk of multiple disabilities (OR=3.01, 95% CI: 1.18–7.71).</div></div><div><h3>Conclusion</h3><div>This study provides disability type-stratified comparative evidence on the heterogeneous manifestations of sleep depressive symptom relationships across different disability types. Six to eight hours of nighttime sleep was associated with reduced depressive symptoms across all disability types, while the associations with napping varied by disability type, suggesting the need for disability-specific individualized sleep intervention strategies.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"3 1","pages":"Article 100256"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147384864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A culturally tailored virtual intervention for Alzheimer’s family caregivers: Addressing practical challenges and future directions","authors":"Dongmi Kim ,&nbsp;Seulgi Ryu ,&nbsp;Wonshik Chee ,&nbsp;Eun-Ok Im","doi":"10.1016/j.aggp.2026.100247","DOIUrl":"10.1016/j.aggp.2026.100247","url":null,"abstract":"<div><h3>Background</h3><div>As interest in virtual care delivery grows, few studies have rigorously explored the real world implementation challenges of culturally tailored, technology-based interventions for Asian American caregivers of persons living with Alzheimer’s Disease (PLAD). This study aims to identify and examine key practical barriers to implementing such interventions and to inform the development of more effective and sustainable virtual support programs.</div></div><div><h3>Methods</h3><div>This study draws on an ongoing virtual intervention targeting Asian American caregivers of PLAD. Data sources include weekly research diaries maintained by intervention team members and meeting minutes from regular team discussions. A simple content analysis was conducted to identify recurring themes and challenges faced during implementation.</div></div><div><h3>Results</h3><div>Seven major challenges were identified: (a) difficulties in retention; (b) concerns regarding participant authenticity and fraudulent cases; (c) technological barriers and challenges with virtual reality (VR) features; (d) variability in cultural tailoring needs; (e) stigma and challenges in building rapport; (f) time zone and geographic constraints; and (g) limited resources available for Asian American caregivers. To address these issues, recommended strategies include: flexible and supportive delivery with progress tracking, multilayered participant verification and education, technical support and intuitive design, bicultural perspectives and ongoing training, trust-building and encouragement of help-seeking behaviors, prioritizing time zone compatibility and providing flexible engagement options, and advocacy for expanded caregiver resources.</div></div><div><h3>Conclusions</h3><div>Practical and cultural challenges must be addressed when designing and delivering technology-based interventions. Incorporating these considerations can enhance caregiver resilience, improve engagement, and support better outcomes for Asian American families affected by AD.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"3 1","pages":"Article 100247"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146022381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between chronic lung disease and chronic heart disease among middle-aged and older adults in India: A gender-stratified cross-sectional analysis","authors":"Hemant Singh Gurjar ,&nbsp;Gaurav Sharma ,&nbsp;Anjna Kumari","doi":"10.1016/j.aggp.2026.100245","DOIUrl":"10.1016/j.aggp.2026.100245","url":null,"abstract":"<div><h3>Background</h3><div>Chronic heart disease (CHD) and chronic lung disease (CLD) are major contributors to morbidity and mortality among ageing populations, often sharing common risk factors and biological pathways. Despite evidence of cardiopulmonary interactions, few studies in India have examined gender differences and effect modification in the association between CLD and CHD using nationally representative data. This study estimates the prevalence of CLD and CHD among Indian adults aged ≥45 years, examines their association, and explores gender differences in the distribution and contribution of BMI, self-rated health, hypertension, diabetes, cancer, stroke, and high cholesterol within this association.</div></div><div><h3>Data and Methods</h3><div>We analysed cross-sectional data from 60,632 respondents in Wave 1 of the LASI (2017–2018). Weighted descriptive statistics and multivariable logistic regression models assessed associations between CLD and CHD, incorporating interaction terms for key health risk factors. Mediation analysis used the Karlson–Holm–Breen method to decompose total effects into direct and indirect effects.</div></div><div><h3>Results</h3><div>The prevalence of CHD and CLD was 3.86% and 7.29%, respectively. Females with CLD had higher odds of CHD (AOR=2.89) than males. Significant interaction effect modifications were observed for SRH, hypertension, high BMI, diabetes, cancer, stroke, and high cholesterol, predominantly among females. Mediation decomposition analysis identified SRH as the strongest mediator, explaining 34% of the observed CLD–CHD association overall (52% in males, 24% in females), followed by hypertension (10%) and high cholesterol (5%).</div></div><div><h3>Conclusion</h3><div>CLD and CHD are more prevalent among middle-aged and older adults in India, with co-occurrence influenced by age, multimorbidity, obesity, poor SRH and cardiometabolic conditions. Gender differences and geographic variation underscore the need for tailored strategies. Recognising CLD–CHD coexistence can inform comprehensive geriatric assessment, risk stratification and coordinated care, while population-level interventions should integrate lifestyle promotion, multimorbidity management and gender-sensitive approaches.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"3 1","pages":"Article 100245"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146173311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychological and functional outcomes of a community-based physical activity program for older adults: A prospective study in Brazil","authors":"Ivon Gretel Winkler Maisonnave ,&nbsp;Clarissa Biehl Printes ,&nbsp;Fabiane de Oliveira Brauner ,&nbsp;Dalvan Griebler ,&nbsp;Rafael Reimann Baptista","doi":"10.1016/j.aggp.2026.100254","DOIUrl":"10.1016/j.aggp.2026.100254","url":null,"abstract":"<div><div>To evaluate longitudinal associations between participation in a community-based, multicomponent physical activity program and changes in depressive symptoms, physical functionality, and fall prevalence among older adults. Prospective cohort study with 12-month follow-up. Citywide program conducted through a public-university partnership in southern Brazil. A total of 500 older adults (≥60 years), referred by public health services or self-enrolled. Priority was given to individuals with chronic conditions and sedentary lifestyles. Structured physical activity program including aerobic, resistance, balance, and flexibility exercises, delivered across indoor, outdoor, aquatic, and gym-based environments. Depressive symptoms (Geriatric Depression Scale, GDS-15), functional performance (30-Second Sit-to-Stand Test, handgrip strength), fall prevalence, and self-rated health. Generalized Estimating Equations (GEE) were used to assess changes over time, considering within-subject correlations. Improvements were observed over the evaluation period. The proportion of participants with depressive symptoms (GDS &gt;5) decreased from 9.6% to 4.9% (p = 0.021). Fall prevalence declined from 27.2% to 14.1% (p &lt; 0.001), and self-rated health improved (p &lt; 0.001). Functional performance measures also showed favorable changes. No evidence of selective attrition was found, sample reductions over time reflected rolling program enrollment. Participation in a multicomponent physical activity program was associated with improvements in psychological well-being and functional health among older adults. These findings support the integration of structured physical activity into community health initiatives aimed at healthy aging.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"3 1","pages":"Article 100254"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146173315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A descriptive study of the annual mobility assessment","authors":"Michael L. Puthoff PT, PhD,&nbsp;Catherine J. Byrne PT, MPT, DHSc","doi":"10.1016/j.aggp.2026.100259","DOIUrl":"10.1016/j.aggp.2026.100259","url":null,"abstract":"<div><h3>Background</h3><div>Preclinical mobility limitations (PCML) begin with subtle changes that might not be perceived but often lead to loss of function. The newly developed Annual Mobility Assessment (AMA) was designed to identify PCML, but to date, there is no published data on the AMA.</div></div><div><h3>Objective</h3><div>To examine the time requirements of the AMA, limitations detected with recommended age and sex normative data, explore the relationship between measures, and describe recommendations based on results.</div></div><div><h3>Methods</h3><div>64 participants, aged 55 years and older, were enrolled. The AMA includes self-reported mobility measures and physical performance tests; usual and fast gait speed, 30 s sit to stand, Four Square Step Test, Timed Up and Go (TUG), and TUG–Cognitive. Participants were classified as having a mobility limitation (ML), PCML, or no PCML based on comparison to normative data. Means and standard deviations were calculated around demographic data and the time required to complete the assessment. The frequency of classifications was counted and the correlation between measures examined.</div></div><div><h3>Results</h3><div>The AMA can be completed in under 30 min. The AMA identified ML or PCML in 31.3% of participants, 23.4% were recommended for a physical therapy examination, and 46.9% referred to a community-based exercise program. Correlation was low between self-reported and physical performance measures, but this may be due to AMA design.</div></div><div><h3>Conclusion</h3><div>The AMA can be completed within a reasonable timeframe, detects limitations, and leads to actionable outcomes. Results raise questions around cut-scores and the relationship between measures, which may guide future updates to the AMA.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"3 1","pages":"Article 100259"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146173312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding barriers and enablers of health insurance awareness among older adults in India: Insights from LASI, 2017–18, with a focus on migration status","authors":"Samrat Sarkar,&nbsp;Sumit Narayan Dwivedi,&nbsp;Reshmi R．S．","doi":"10.1016/j.aggp.2026.100253","DOIUrl":"10.1016/j.aggp.2026.100253","url":null,"abstract":"<div><h3>Background</h3><div>Awareness of health insurance is uneven among older adults in India and remains a critical barrier to enrolment. This study examines the social and structural factors associated with health insurance unawareness among uninsured older adults in India, with particular attention to migration status.</div></div><div><h3>Data &amp; Methods</h3><div>Data were drawn from Wave 1 of the Longitudinal Ageing Study in India (LASI, 2017–18). The analysis was restricted to uninsured older adults. Chi-square tests and binary logistic regression models were used to examine associations between migration status, socio-demographic characteristics, and health insurance unawareness.</div></div><div><h3>Results</h3><div>Model 1 shows that non-migrant older adults are 7% more likely to be unaware of health insurance than migrants [UOR: 1.07*, CI: 1.04–1.12]. Higher education reduces this likelihood, with older adults at higher education levels having 78% lower odds of unawareness [UOR: 0.22, CI: 0.20–0.23]. In Model 2, after adjusting for all factors, non-migrants continue to show higher odds of unawareness [AOR: 1.12***, CI: 1.08–1.17]. Urban residents are less likely to be unaware than rural residents [AOR: 0.57, CI: 0.55–0.60], and those living with a spouse also show lower odds compared to individuals living alone [AOR: 0.76***, CI: 0.64–0.90]. **</div></div><div><h3>Conclusion</h3><div>Migration status, education, and social factors are significantly associated with health insurance unawareness among older adults. Non-migrants, older adults with low education, rural residents, and those living alone or in poorer conditions are more likely to be unaware of health insurance. Promoting insurance literacy can help to increase awareness.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"3 1","pages":"Article 100253"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146173313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between locomotive syndrome and pre-frailty in community-dwelling older adults: A cross-sectional study","authors":"Junji Nishimoto ,&nbsp;Kazuaki Hamada ,&nbsp;Naoki Deguchi ,&nbsp;Ryo Tanaka","doi":"10.1016/j.aggp.2025.100230","DOIUrl":"10.1016/j.aggp.2025.100230","url":null,"abstract":"<div><h3>Background</h3><div>In super-aged societies, preventing frailty is a key public health priority to ensure longer, healthier lives. Locomotive syndrome (LS), defined as impaired mobility because of musculoskeletal dysfunction, is a modifiable risk factor for frailty. However, the association between LS severity and pre-frailty has not yet been fully elucidated. This study sought to clarify whether the degree of LS is related to pre-frailty among community-dwelling older adults.</div></div><div><h3>Methods</h3><div>This cross-sectional analysis included data from the DETECt-L cohort (2021–2024). The severity of LS was evaluated in adults aged 65 years and older using three measures: the two-step test, the stand-up test, and the 25-item Geriatric Locomotive Function Scale. Pre-frailty was assessed using the Japanese adaptation of the Cardiovascular Health Study criteria. The association between LS severity and pre-frailty was analyzed using binary logistic regression, with adjustments for age, sex, body mass index, back and knee pain, and history of falls.</div></div><div><h3>Results</h3><div>Among 512 participants, the prevalence of pre-frailty increased with LS severity. Compared with participants in the non-LS, the proportion of pre-frailty was higher in LS stage 2 (OR: 2.184, 95% CI: 1.094–4.358, <em>P</em> = 0.027), and the same was true for LS stage 3 (OR: 2.254, 95% CI: 1.032–4.922, <em>P</em> = 0.041).</div></div><div><h3>Conclusions</h3><div>In independently living older adults, LS stage 2 or higher was significantly associated with pre-frailty. Preventing the transition from stage 1 to stage 2 may help reduce pre-frailty risk and support healthy aging. Early orthopedic management of LS could serve as a strategic approach to mitigate frailty in super-aged societies.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"3 1","pages":"Article 100230"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145618485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}