The Royal Society of Chemistry最新文献_第6页

Retraction: The iron group transition-metal (Fe, Ru, Os) coordination of Se-doped graphitic carbon (Se@g-C3N4) nanostructures for the smart therapeutic delivery of zidovudine (ZVD) as an antiretroviral drug: a theoretical calculation perspective

IF 3.9 3区化学

RSC Advances Pub Date : 2025-04-04 DOI: 10.1039/D5RA90039E

Favour A. Nelson, Hitler Louis, Innocent Benjamin and Rawlings A. Timothy

引用次数: 0

Novel poly-deep eutectic solvent-functionalized magnetic graphene oxide nanomaterials for high-performance solid-phase extraction of trypsin.

IF 2.7 3区化学

Analytical Methods Pub Date : 2025-04-04 DOI: 10.1039/d5ay00252d

Jing Chen, Xiyan He, Yuzhi Wang

{"title":"Novel poly-deep eutectic solvent-functionalized magnetic graphene oxide nanomaterials for high-performance solid-phase extraction of trypsin.","authors":"Jing Chen, Xiyan He, Yuzhi Wang","doi":"10.1039/d5ay00252d","DOIUrl":"https://doi.org/10.1039/d5ay00252d","url":null,"abstract":"Three novel polymethacrylic acid-based deep eutectic solvent (DES)-functionalized magnetic graphene oxide composites were designed and successfully synthesized via the radical polymerization method. The aim was to achieve the selective solid-phase extraction of trypsin (Tryp). Among them, the magnetic extractant (MGO@PDES2) functionalized with a poly-deep eutectic solvent composed of tetraethylammonium chloride and methylpropionic acid at a molar ratio of 1 : 2 exhibited the highest extraction efficiency for Tryp. Owing to the high specific surface area of MGO and the abundant carboxyl functional groups in PDES2, the prepared MGO@PDES2 exhibited excellent selectivity and stability for Tryp extraction. Under optimal conditions, the extraction capacity of Tryp by MGO@PDES2 reached 708.85 mg g-1. The extraction driving forces between MGO@PDES2 and Tryp were hydrogen-bonding interactions and electrostatic interactions. Among the seven biomacromolecules, MGO@PDES2 displayed outstanding selectivity for Tryp. In addition, the results of cycling experiments indicated that MGO@PDES2 could be reused many times without a significant change in extraction capacity. Moreover, the proposed method was successfully applied to extract Tryp from the crude extract of bovine pancreas, yielding satisfactory results. All the results suggest that MGO@PDES2 is a promising magnetic extractant, which is expected to provide new ideas for the extraction and separation of proteins.","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143778548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Microfiber suspensions for the removal of adhered colloids from surfaces, microdevices, and cavities.

IF 2.9 3区化学

Soft Matter Pub Date : 2025-04-04 DOI: 10.1039/d5sm00065c

Marcel M Louis, Samantha A McBride, Janine K Nunes, Antonio Perazzo, Christopher A Kuchar, Mohamed E Labib, Howard A Stone

{"title":"Microfiber suspensions for the removal of adhered colloids from surfaces, microdevices, and cavities.","authors":"Marcel M Louis, Samantha A McBride, Janine K Nunes, Antonio Perazzo, Christopher A Kuchar, Mohamed E Labib, Howard A Stone","doi":"10.1039/d5sm00065c","DOIUrl":"https://doi.org/10.1039/d5sm00065c","url":null,"abstract":"Effective methods for cleaning surfaces are important for applications including dentistry, healthcare, micro-devices, and the manufacturing of electronic components and semiconductors. For example, surgical and dental instruments are susceptible to accumulation of aggregates and biofilm formation, which can lead to cross-contamination when ineffectively cleaned and reused. Complex fluids such as micro-fibrillated cellulose (MFC) can greatly assist in mechanically cleaning surfaces by removing strongly adhered aggregates without abrading the underlying material. We demonstrate that the heterogeneous structure of micro-fibrillated cellulose is effective in removing adhered particulates from surfaces and we characterize the cleaning efficiency of MFC suspensions in representative flow configurations. The experiments reported here involve flowing MFC solutions at various concentrations and at controlled shear rates through a rectangular microfluidic channel. Fluorescence microscopy is used to measure the removal of fluorescent particles that are adhered to the glass surface of the microfluidic device by electrostatic and surface forces. The particle removal with time is analyzed for each concentration of the MFC suspension and each shear rate to determine cleaning effectiveness. The rheology of the MFC solutions is also characterized and correlated to cleaning performance. We find that cleaning effectiveness increases with increasing fiber concentration and with increasing shear rate. Additionally, we compared the cleaning performance of the MFC suspensions with fluids that share similar rheological properties to highlight the role of shear thinning, elasticity, and tribology. Finally, we examine how sharp corners/edges within a microfluidic channel hinder cleaning and identify strategies for mitigating this hindrance.","PeriodicalId":103,"journal":{"name":"Soft Matter","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143778587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fe-N-C oxidase-mimicking nanozymes for discrimination of antioxidants and detection of Hg².

IF 2.7 3区化学

Analytical Methods Pub Date : 2025-04-04 DOI: 10.1039/d5ay00313j

Shushu Chu, Mingyuan Xia, Peng Xu, Xueli Zhang, Wendong Liu, Yizhong Lu

{"title":"Fe-N-C oxidase-mimicking nanozymes for discrimination of antioxidants and detection of Hg2.","authors":"Shushu Chu, Mingyuan Xia, Peng Xu, Xueli Zhang, Wendong Liu, Yizhong Lu","doi":"10.1039/d5ay00313j","DOIUrl":"https://doi.org/10.1039/d5ay00313j","url":null,"abstract":"Single-atom nanozymes (SAzymes) with high atom utilization efficiency and well-defined coordination structures have been extensively studied. However, research on the use of the enzyme-like activity of SAzymes for the detection and discrimination of antioxidants remains relatively limited. Herein, synthesized Fe-N-C SAzymes (FeN4) display excellent oxidase-like activity with a maximum reaction rate of 1.083 × 10-7 M s-1, which is 40.85 times higher than that for NC nanozymes. Experimental studies and density functional theory (DFT) calculations revealed that the high catalytic performance arises from the efficient absorption and activation of O2 at highly exposed Fe sites. Based on the different inhibitory effects of ascorbic acid (AA), glutathione (GSH), and cysteine (Cys), a colorimetric sensor array for identifying antioxidants was developed. AA, GSH, and Cys were effectively distinguished through linear discriminant analysis (LDA). Moreover, a colorimetric platform for the rapid detection of trace Hg2+ was successfully presented, taking advantage of the strong binding ability between -SH of Cys and Hg2+, and achieving an impressive limit of detection (LOD) of 9.29 nM. This work not only provides a novel concept for distinguishing antioxidants but also expands the application of nanozymes in heavy metal ion detection.","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143778544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of hydration, material properties, and pore structure of polymers enhanced with dendritic fibrous nanosilica as a concrete additive

IF 3.9 3区化学

RSC Advances Pub Date : 2025-04-03 DOI: 10.1039/D5RA00985E

Mohammad Azizi, Amin Honarbakhsh, Seyed Mojtaba Movahedifar, Mehdi Nobahari and Rahele Zhiani

{"title":"Analysis of hydration, material properties, and pore structure of polymers enhanced with dendritic fibrous nanosilica as a concrete additive","authors":"Mohammad Azizi, Amin Honarbakhsh, Seyed Mojtaba Movahedifar, Mehdi Nobahari and Rahele Zhiani","doi":"10.1039/D5RA00985E","DOIUrl":"https://doi.org/10.1039/D5RA00985E","url":null,"abstract":"Different cement-based grouting and repair materials have been created and are commonly employed in construction renovation projects. Nevertheless, conventional cement mortars face challenges like limited corrosion resistance and weak bonding strength. Polymers, commonly used as modifiers for repair mortars, provide enhanced mechanical properties, increased resistance to corrosion, and better bonding. Despite these advantages, many polymer modifiers are inherently limited in preventing crack initiation and propagation, while also increasing costs. This study incorporated different amounts of three types of polymers supported on dendritic fibrous nanosilica (DFNS-polymers) into cement mortar to evaluate their effects on mortar performance, pore structure, and cement hydration. The addition of DFNS-polymers significantly improved the durability and workability of the mortar. Moreover, the pore structure was optimized, resulting in a more balanced pore distribution and a reduction in pore and porosity size. This research introduces an effective approach to enhancing the performance of repair mortars by combining polymers with suitable fillers.","PeriodicalId":102,"journal":{"name":"RSC Advances","volume":" 13","pages":" 10215-10226"},"PeriodicalIF":3.9,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/ra/d5ra00985e?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143761644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cluster-directed ionic framework supramolecular hydrogel with high-temperature tolerability and enhanced water evaporation.

IF 2.9 3区化学

Soft Matter Pub Date : 2025-04-03 DOI: 10.1039/d5sm00004a

Jiaxu Wang, Liang Yue, Mingfeng Wei, Bao Li, Lixin Wu

引用次数: 0

Multichannel microperfusion cell-capture system for screening anticancer active ingredients in traditional Chinese medicine formulas.

IF 2.7 3区化学

Analytical Methods Pub Date : 2025-04-03 DOI: 10.1039/d5ay00205b

Doudou Xu, Yi Tian, Dan Tie, Shuang Hu, Rongrong Xing, Xuan Chen

{"title":"Multichannel microperfusion cell-capture system for screening anticancer active ingredients in traditional Chinese medicine formulas.","authors":"Doudou Xu, Yi Tian, Dan Tie, Shuang Hu, Rongrong Xing, Xuan Chen","doi":"10.1039/d5ay00205b","DOIUrl":"https://doi.org/10.1039/d5ay00205b","url":null,"abstract":"The screening of effective active ingredients from traditional Chinese medicine (TCM) formulas is currently a key focus of research. In this study, a multichannel microperfusion cell-capture system utilizing human hepatocellular carcinoma HepG2 cells was established and used to screen for anticancer active ingredients in the ancient formula Huangqisan. A polypropylene solid film carrying HepG2 cells was used as the cell-capture platform, and a multichannel microperfusion system was utilized for perfusion, enabling the screening of multiple ingredients' activities. This study optimized the main factors influencing the screening results and conducted a methodological examination under the optimal screening conditions. The method was coupled with high-performance liquid chromatography (HPLC) to analyze and identify the anticancer ingredients in Huangqisan. The optimal conditions were determined as follows: use of a polypropylene film as the cell support, a 7 mL sample phase solution (3 μg mL-1) for perfusion, and a screening duration of 30 min. After screening, eight anticancer active ingredients in Huangqisan, namely, calycosin, calycosin glycoside, formononetin, ononin, genistein, isorhamnetin, puerarin, and morin, were preliminarily determined by comparing their chromatographic retention times and peak areas with standard substances. The cell fishing factor (CFF) of these ingredients ranged from 1.1 to 19.8. In summary, the use of a multichannel microperfusion cell-capture system combined with HPLC enabled the screening of the anticancer active ingredients in Huangqisan. This method thus provides a new approach for screening complex TCM matrices and holds promising prospects for future development.","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143770759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

OBOC screening of high activity and low-toxic polymyxin analogs against MCR-1 resistant strains.

IF 5.8 3区医学

Biomaterials Science Pub Date : 2025-04-03 DOI: 10.1039/d5bm00362h

Wenhong Zheng, Xin Wang, Hao Lian, Pengfei Zou, Tongyi Sun, Hao Wang, Li-Li Li

引用次数: 0

Unveiling mechanistic insights and applications of aggregation-enhanced emission (AEE)-active polynuclear transition metal complexes.

IF 4.3 2区化学

Chemical Communications Pub Date : 2025-04-03 DOI: 10.1039/d5cc00690b

Bishnu Das

{"title":"Unveiling mechanistic insights and applications of aggregation-enhanced emission (AEE)-active polynuclear transition metal complexes.","authors":"Bishnu Das","doi":"10.1039/d5cc00690b","DOIUrl":"https://doi.org/10.1039/d5cc00690b","url":null,"abstract":"Aggregation-enhanced emission (AEE) in polynuclear transition metal complexes (PTMCs) represents a major advancement in luminescent materials, overcoming the limitations of aggregation-caused quenching (ACQ) in traditional systems. Unlike conventional materials that suffer from quenching, AEE-active PTMCs exhibit enhanced luminescence in the aggregated state, driven by mechanisms such as restricted molecular motion, π-π stacking, and metal-metal interactions. These properties make PTMCs highly versatile for applications including chemical sensing, bioimaging, photodynamic therapy (PDT), optoelectronics (e.g., OLEDs, WOLEDs, and LEDs), and security technologies (e.g., anti-counterfeiting inks). They enable the sensitive detection of pollutants, facilitate high-performance bioimaging, and enhance the efficiency of energy devices. However, PTMCs face several challenges, including complex synthesis, limited thermal and photostability, solubility issues, and environmental and toxicity concerns. Additionally, high production costs, instability in different media, and the need for optimized energy transfer efficiency must be addressed to enhance their practical performance. This review explores the mechanisms behind AEE in PTMCs and discusses strategies for overcoming these challenges, including ligand engineering, hybrid material development, and sustainable synthesis methods. It also highlights their potential in advancing energy-efficient technologies, precision therapeutics, and secure communication systems, contributing to a more sustainable and innovative future.","PeriodicalId":67,"journal":{"name":"Chemical Communications","volume":" ","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143770762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

MnO₂-coated necklace-like CoFe@carbon nanofiber composites for superior electromagnetic wave absorption.

IF 12.2 2区材料科学

Materials Horizons Pub Date : 2025-04-03 DOI: 10.1039/d4mh01783h

Yiliang Liu, Ying Lin, Zhixin Cai, Yongzhen Ma, Hongwei Zhou, Wei Chai, Qibin Yuan, Haibo Yang

{"title":"MnO2-coated necklace-like CoFe@carbon nanofiber composites for superior electromagnetic wave absorption.","authors":"Yiliang Liu, Ying Lin, Zhixin Cai, Yongzhen Ma, Hongwei Zhou, Wei Chai, Qibin Yuan, Haibo Yang","doi":"10.1039/d4mh01783h","DOIUrl":"https://doi.org/10.1039/d4mh01783h","url":null,"abstract":"With the rapid development of modern electronic technology, electromagnetic wave (EMW) absorption materials play a crucial role in solving the problem of electromagnetic radiation pollution. By designing unique microstructures or composite magnetic components, the EMW attenuation ability of carbon nanofibers (CNFs) can be enhanced. However, the ultra-high conductivity of CNFs leads to impedance mismatch, necessitating the introduction of components that can rapidly optimize dielectric properties for improved impedance matching. In this study, Co0.7Fe0.3@CNFs@MnO2 (CFCM) was fabricated by coating MnO2 nanosheets on necklace-like CoFe@carbon nanofiber composites. The coated MnO2 nanosheets not only enhance the EMW attenuation ability, but also improve impedance matching. The results indicate that the minimum reflection loss of the sample is -62.7 dB, and the effective absorption bandwidth reaches 6.5 GHz. This work presents a valuable method to prepare outstanding EMW absorption materials with a necklace-like 3D network hierarchical structure.","PeriodicalId":87,"journal":{"name":"Materials Horizons","volume":" ","pages":""},"PeriodicalIF":12.2,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143770768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0