镍催化的Chan-Lam偶联：环境条件下n -芳基化2-氨基苯并噻唑的有效途径

IF 4.6 3区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

RSC Advances Pub Date : 2025-10-16 DOI:10.1039/D5RA06530E

Rose Mary Philip, P. S. Devi and Gopinathan Anilkumar

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引用次数: 0

摘要

在温和的反应条件下，镍催化2-氨基苯并噻唑和芳基硼酸的C-N偶联。在露天条件下，在Ni/4,4 ' -dOMebpy催化体系的存在下，得到n-芳基化的2-氨基苯并噻唑。该方法涵盖了广泛的适用底物，包括芳基硼酸和2-氨基苯并噻唑，在短的反应时间内以中等到良好的产率提供相应的C-N偶联产物。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Nickel-catalyzed Chan–Lam coupling: an efficient route to N-arylated 2-aminobenzothiazoles under ambient conditions

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Nickel-catalyzed Chan–Lam coupling: an efficient route to N-arylated 2-aminobenzothiazoles under ambient conditions

A nickel-catalyzed C–N coupling of 2-aminobenzothiazoles and aryl boronic acids under mild reaction conditions is disclosed. The reaction afforded N-arylated 2-aminobenzothiazoles in the presence of a Ni/4,4′-dOMebpy catalytic system under open-air conditions. The method encompasses a wide range of applicable substrates, including aryl boronic acids and 2-aminobenzothiazoles, affording the corresponding C–N coupled products in moderate to good yields in short reaction times.

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来源期刊

RSC Advances chemical sciences-

CiteScore

7.50

自引率

2.60%

发文量

3116

审稿时长

1.6 months

期刊介绍： An international, peer-reviewed journal covering all of the chemical sciences, including multidisciplinary and emerging areas. RSC Advances is a gold open access journal allowing researchers free access to research articles, and offering an affordable open access publishing option for authors around the world.