The Royal Society of Chemistry最新文献_第7页

Nondestructive presymptomatic detection of blue-fluorescing substances in tomato leaves infected with Ralstonia solanacearum using a polyvinyl alcohol hydrogel. 聚乙烯醇水凝胶法对茄枯病番茄叶片中蓝色荧光物质的症状前无损检测

IF 2.7 3区化学

Analytical Methods Pub Date : 2025-07-25 DOI: 10.1039/d5ay00579e

Shigeyuki Iwasa, Yuso Kobara, Katsumi Maeda, Arina Asano, Tatsuya Shimanuki, Kuniaki Nagamine

引用次数: 0

Synergistic peptide-organic matrix enhances mineralization of biomimetic scaffolds for bone regeneration. 协同肽-有机基质增强骨再生仿生支架的矿化。

IF 12.2 2区材料科学

Materials Horizons Pub Date : 2025-07-24 DOI: 10.1039/d5mh00969c

Yawen Huang, Ziqi Zhao, Yu Yang, Ruiqi Mao, Dongxuan Li, Fengxiong Luo, Kefeng Wang, Yujiang Fan, Xingdong Zhang

{"title":"Synergistic peptide-organic matrix enhances mineralization of biomimetic scaffolds for bone regeneration.","authors":"Yawen Huang, Ziqi Zhao, Yu Yang, Ruiqi Mao, Dongxuan Li, Fengxiong Luo, Kefeng Wang, Yujiang Fan, Xingdong Zhang","doi":"10.1039/d5mh00969c","DOIUrl":"https://doi.org/10.1039/d5mh00969c","url":null,"abstract":"Biomimetic mineralized composites engineered via organic matrix templating show promise for bone repair but suffer from poor mineralization and imbalanced mechanical-biological performance. This study synergistically regulated biomolecules and organic matrix properties to enhance in situ mineralization, thereby improving mechanical strength and osteogenic potential. A nucleation-domain containing peptide (HGRGEAFDY) screened through molecular dynamics simulation was integrated into the gelatin matrix to prepare biomimetic materials with enhanced mineralization performance. The influence of peptide and organic matrix properties on mineralization capacity and saturation of in situ mineralization (SIM) was investigated. Results demonstrated that peptides with characteristic nucleation domains can boost mineralization by providing more nucleation sites and strengthening organic-inorganic interactions. Meanwhile, matrix compactness negatively correlated with mineralization capacity and SIM. Combined modulation of peptide nucleation ability and matrix compactness can enhance the SIM of the matrix, increasing the amount of minerals while improving mechanical properties. The biomimetic composites/scaffolds with mineralization enhancement by peptide-organic matrix regulation were evidenced to promote cell proliferation and osteogenic differentiation, and in vivo bone regeneration by upregulating BMP2 gene expression. This study provides valuable insights into the design of biomimetic mineralized materials and offers strategies for developing bone repair scaffolds with improved mechanical and biological performance.","PeriodicalId":87,"journal":{"name":"Materials Horizons","volume":" ","pages":""},"PeriodicalIF":12.2,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144697053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thermosensitive liposomal nanomedicine-functionalized photothermal composite scaffolds for light-guided cancer therapy. 用于光导癌症治疗的热敏脂质体纳米药物功能化光热复合支架。

IF 12.2 2区材料科学

Materials Horizons Pub Date : 2025-07-24 DOI: 10.1039/d5mh00888c

Xiaohan Liu, Huajian Chen, Man Wang, Tianjiao Zeng, Toru Yoshitomi, Naoki Kawazoe, Yingnan Yang, Guoping Chen

{"title":"Thermosensitive liposomal nanomedicine-functionalized photothermal composite scaffolds for light-guided cancer therapy.","authors":"Xiaohan Liu, Huajian Chen, Man Wang, Tianjiao Zeng, Toru Yoshitomi, Naoki Kawazoe, Yingnan Yang, Guoping Chen","doi":"10.1039/d5mh00888c","DOIUrl":"https://doi.org/10.1039/d5mh00888c","url":null,"abstract":"In breast cancer treatment, the elimination of residual cancer cells in a sustainable and controllable manner to prevent recurrence remains a critical challenge in postoperative adjuvant therapy. In this study, a novel implantable in situ therapeutic composite scaffold platform (ALA@lipo/Au/Gel/PGA) was developed based on a porous scaffold composed of biocompatible gelatin and polyglutamic acid (PGA). This platform incorporated the photothermal agent Au nanorods (AuNRs) and thermosensitive liposomes encapsulated with the photosensitizer precursor 5-aminolevulinic acid (ALA). Due to the satisfactory photothermal conversion effect of the ALA@lipo/Au/Gel/PGA composite scaffold, the use of near-infrared (NIR) light not only ablated the cancer cells in the scaffold through photothermal therapy (PTT) but also induced the accelerated release of encapsulated ALA from the thermosensitive liposomes. After uptake, ALA could generate cytotoxic reactive oxygen species to increase tumour cell elimination efficiency via photodynamic therapy (PDT). Both in vitro and in vivo experiments demonstrated the synergistic anticancer effects of the composite scaffold. These results highlight the potential of this phototherapy-induced composite scaffold as a new synergistic treatment method for breast cancer.","PeriodicalId":87,"journal":{"name":"Materials Horizons","volume":" ","pages":""},"PeriodicalIF":12.2,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144697054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Distinct impact of polystyrene microplastics on six species of common pathogenic and probiotic bacteria and their boosting support to Vibrio cholerae proliferation. 聚苯乙烯微塑料对六种常见致病菌和益生菌的不同影响及其对霍乱弧菌增殖的促进作用。

IF 4.3 3区环境科学与生态学

Environmental Science: Processes & Impacts Pub Date : 2025-07-24 DOI: 10.1039/d5em00219b

Tingting Gu, Yue Liu, Yongjie Wang, Huajun Zheng, Lanming Chen

{"title":"Distinct impact of polystyrene microplastics on six species of common pathogenic and probiotic bacteria and their boosting support to Vibrio cholerae proliferation.","authors":"Tingting Gu, Yue Liu, Yongjie Wang, Huajun Zheng, Lanming Chen","doi":"10.1039/d5em00219b","DOIUrl":"https://doi.org/10.1039/d5em00219b","url":null,"abstract":"Along with the widespread application of plastics, the release of polystyrene microplastics (PS-MPs) into the environment raises concerns about the risks of PS-MPs to human health. Hence, in this study, we investigated for the first time the impact of PS-MPs with different diameters on six species of common pathogenic and probiotic bacteria and further deciphered molecular mechanisms underlying the boosting support of PS-MPs for Vibrio cholerae proliferation. The results revealed that PS-MPs (100 nm to 5 μm, 0.1-100 mg L-1) promoted the reproduction of V. cholerae, but blocked the growth of Vibrio parahaemolyticus, Klebsiella pneumoniae, Klebsiella oxytoca, Staphylococcus aureus, and Lactobacillus plantarum, showing different size- and concentration-dependent action modes. The PS-MPs (100 nm to 5 μm, 100 mg L-1) significantly reduced the negative charge on the cell surface of V. cholerae and consequently increased the bacterial cell surface hydrophobicity and membrane fluidity, biofilm formation and self-aggregation capacity (p < 0.05). Comparative transcriptome analysis uncovered significantly up-regulated metabolic pathways in V. cholerae after exposure to the PS-MPs (100 nm, 100 mg L-1) for 8 h, leading to enhanced chemotaxis, flagellar motility, biofilm formation, energy metabolism and antioxidant defense. In vitro cell model experiments showed that the pre-exposure significantly increased the adhesion and invasion percentages of V. cholerae on human Caco-2 cells (p < 0.05). Overall, the results of this study not only fill the gaps in the interaction between the PS-MPs and common bacteria, but also highlight the amplified hazard of co-pollution by PS-MPs and V. cholerae, a leading waterborne pathogen worldwide.","PeriodicalId":74,"journal":{"name":"Environmental Science: Processes & Impacts","volume":" ","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144697138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction: Bromelain: a review of its mechanisms, pharmacological effects and potential applications. 更正：菠萝蛋白酶：其机制，药理作用和潜在应用的综述。

IF 5.1 1区农林科学

Food & Function Pub Date : 2025-07-24 DOI: 10.1039/d5fo90061a

Virender Kumar, Bharti Mangla, Shamama Javed, Waquar Ahsan, Pankaj Kumar, Vandana Garg, Harish Dureja

引用次数: 0

Co-motion of catalytic tubes and host droplets on superhydrophobic surfaces. 催化管和宿主液滴在超疏水表面上的共同运动。

IF 2.9 3区化学

Soft Matter Pub Date : 2025-07-24 DOI: 10.1039/d5sm00576k

Amrutha S V, Oliver Steinbock

引用次数: 0

Correction: NHC-catalysed synthesis of hydroxy methylene-bridged formyl-di-xylofuranose: access to tetrakis and spiro tricyclic xylofuranose. 更正：nhc催化合成羟基亚甲基桥接甲酰基二羟基呋喃糖：可得四环和螺三环羟基呋喃糖。

IF 2.9 3区化学

Organic & Biomolecular Chemistry Pub Date : 2025-07-24 DOI: 10.1039/d5ob90094h

Norein Sakander, Rahul Haldar, Debaraj Mukherjee

引用次数: 0

Recent advances in the synthesis of multiple helicenes. 多重螺旋烯合成的最新进展。

IF 2.9 3区化学

Organic & Biomolecular Chemistry Pub Date : 2025-07-24 DOI: 10.1039/d5ob00966a

Zhen Chen, Wei-Chen Guo, Chuan-Feng Chen

引用次数: 0

Electrochemical [3 + 2] cycloaddition of anilines and enamine ketones: construction of 3-benzoylindole derivatives. 苯胺和烯胺酮的电化学[3 + 2]环加成：3-苯并酰吲哚衍生物的构建。

IF 2.9 3区化学

Organic & Biomolecular Chemistry Pub Date : 2025-07-24 DOI: 10.1039/d5ob00831j

Yangyang Hu, Chunlei Yu, Ya'nan Ran, Miao Yu, Jingwen Sun, Huiying Liu, Jiahui Zhang, Haijun Wang, Lei Liu

引用次数: 0

Fabrication of robust polyimide-coated solid phase microextraction fibers for efficient extraction of fifteen polycyclic aromatic hydrocarbons from environmental water† 聚酰亚胺包覆固相微萃取纤维的制备，用于从环境水中高效提取15种多环芳烃

IF 3.9 3区化学

RSC Advances Pub Date : 2025-07-24 DOI: 10.1039/D5RA00390C

Aiying Song, Rong Liu, Xinghe He and Linlin Wei

{"title":"Fabrication of robust polyimide-coated solid phase microextraction fibers for efficient extraction of fifteen polycyclic aromatic hydrocarbons from environmental water†","authors":"Aiying Song, Rong Liu, Xinghe He and Linlin Wei","doi":"10.1039/D5RA00390C","DOIUrl":"https://doi.org/10.1039/D5RA00390C","url":null,"abstract":"A novel supporting material was developed by pulling melted glass onto stainless steel, providing a mechanically robust and chemically stable substrate. A polyimide-coated fiber for solid-phase microextraction (SPME) was then fabricated using a simple dipping method. The strong interactions between the polyimide coating and analytes, attributed to abundant unshared electron pairs in the p orbitals of O and N atoms, as well as π electrons in the C<img>O bond and benzene ring, contributed to the high extraction efficiency for sixteen polycyclic aromatic hydrocarbons. The developed polyimide-coated fiber-based SPME method, coupled with gas chromatography-flame ionization detection, exhibited low limits of detection (0.11–1.23 μg L−1) and a wide linear range (1–500 μg L−1) for polycyclic aromatic hydrocarbons in water samples. The method demonstrated excellent repeatability, with single-fiber repeatability ranging from 2.9% to 6.9% and fiber-to-fiber reproducibility between 3.9% and 11.5%. The recoveries of the analytes were between 82.7% and 107.2%. Additionally, the fiber exhibited outstanding durability, maintaining its extraction performance after more than 150 uses. The developed method was successfully applied for the determination of polycyclic aromatic hydrocarbons in river, pond, and sewage water samples, highlighting its potential as a sensitive, reliable, and cost-effective tool for environmental analysis.","PeriodicalId":102,"journal":{"name":"RSC Advances","volume":" 15","pages":" 11826-11834"},"PeriodicalIF":3.9,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/ra/d5ra00390c?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144695678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0