Child's Nervous System最新文献

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Chondroblastoma of the occipital bone with aneurysmal bone cyst: A rare case report. 枕骨软骨母细胞瘤伴动脉瘤样骨囊肿:罕见病例报告。
IF 1.3 4区 医学
Child's Nervous System Pub Date : 2024-11-06 DOI: 10.1007/s00381-024-06632-0
Dexi Bi, Zihao Wang, Zhibo Dai, Shichun Yang, Gao Zeng, Ligang Wang
{"title":"Chondroblastoma of the occipital bone with aneurysmal bone cyst: A rare case report.","authors":"Dexi Bi, Zihao Wang, Zhibo Dai, Shichun Yang, Gao Zeng, Ligang Wang","doi":"10.1007/s00381-024-06632-0","DOIUrl":"https://doi.org/10.1007/s00381-024-06632-0","url":null,"abstract":"<p><strong>Background: </strong>Chondroblastoma is a rare, benign bone tumor originating from immature chondrocytes, typically found in the epiphyseal plates of long bones. Its occurrence in the skull, particularly the occipital bone, is extremely rare.</p><p><strong>Case presentation: </strong>We report a 10-year-old girl presenting with paroxysmal dizziness, occipital pain, and a palpable mass. Imaging studies revealed an osteolytic lesion in the occipital bone with a multiloculated appearance, indicating a concomitant aneurysmal bone cyst. The patient underwent craniotomy with complete tumor excision. Postoperative follow-up showed no neurological deficits or complications and MRI confirmed no recurrence.</p><p><strong>Conclusion: </strong>This case highlights the rare presentation of occipital bone chondroblastoma and emphasizes the importance of early surgical intervention for positive outcomes in pediatric patients.</p>","PeriodicalId":9970,"journal":{"name":"Child's Nervous System","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142582356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Weekly vindesine as second-line chemotherapy in pediatric low-grade glioma. 小儿低级别胶质瘤的二线化疗--每周一次的文迪新。
IF 1.3 4区 医学
Child's Nervous System Pub Date : 2024-11-01 Epub Date: 2024-07-31 DOI: 10.1007/s00381-024-06557-8
Anan Zhang, Xiaoxia Wang, Godfrey C F Chan, Anthony P Y Liu, Yijin Gao
{"title":"Weekly vindesine as second-line chemotherapy in pediatric low-grade glioma.","authors":"Anan Zhang, Xiaoxia Wang, Godfrey C F Chan, Anthony P Y Liu, Yijin Gao","doi":"10.1007/s00381-024-06557-8","DOIUrl":"10.1007/s00381-024-06557-8","url":null,"abstract":"","PeriodicalId":9970,"journal":{"name":"Child's Nervous System","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141859156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Brachial plexus peripheral nerve sheath tumors (PNSTs): clinical and surgical management in the pediatric population. 臂丛周围神经鞘瘤(PNST):儿科临床和手术治疗。
IF 1.3 4区 医学
Child's Nervous System Pub Date : 2024-11-01 Epub Date: 2024-06-28 DOI: 10.1007/s00381-024-06509-2
Fernando Guedes, Evelina Llorian, Vinícius M Henriques, Francisco José Lourenço Torrão-Junior
{"title":"Brachial plexus peripheral nerve sheath tumors (PNSTs): clinical and surgical management in the pediatric population.","authors":"Fernando Guedes, Evelina Llorian, Vinícius M Henriques, Francisco José Lourenço Torrão-Junior","doi":"10.1007/s00381-024-06509-2","DOIUrl":"10.1007/s00381-024-06509-2","url":null,"abstract":"<p><strong>Purpose: </strong>Peripheral nerve sheath tumors (PNSTs) are rare in pediatric patients, especially in the brachial plexus. Research on PNSTs is lacking. This article presents a retrospective cohort study of pediatric patients diagnosed and treated with PNSTs, specifically brachial plexus tumors.</p><p><strong>Methods: </strong>All pediatric patients intervened in a single center between 2007 and 2023 with brachial plexus tumors were systemically analyzed.</p><p><strong>Results: </strong>Eleven pediatric patients with 14 brachial plexus PNSTs were studied. The gender distribution was 64% female and 36% male, with an average age of 10.7 years. Ninety-one percent had a previous NF-1 diagnosis. Right brachial plexus presented a higher prevalence (64%). Pain, Tinel's sign, and stiffness masses were common during diagnosis. Motor deficits were noted in 43% of the patients. Surgery was indicated for symptoms, particularly pain and rapid growth, increasing malignancy risk. Due to suspected malignancy, an en bloc resection with safety margins was performed. Among the patients, 57% received a histopathological diagnosis of MPNST (malignant peripheral nerve sheath tumor). Treatment included radiotherapy and chemotherapy. Clinical follow-up was conducted for all cases, involving clinical and oncological evaluations for all MPNSTs.</p><p><strong>Conclusions: </strong>This article present a series of pediatric brachial plexus tumors, especially in NF-1, and emphasizes the importance of thorough evaluation for this group. Swift diagnosis is crucial in pediatrics, enabling successful surgery for small lesions with limited neurological symptoms, improving long-term outcomes. Prompt referral to specialized services is urged for suspected masses, irrespective of neurological symptoms. Benign tumor postsurgical progression shows better outcomes than MPNSTs, with complete resection as the primary goal. Needle-guided biopsy is not recommended.</p>","PeriodicalId":9970,"journal":{"name":"Child's Nervous System","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141466552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recurrent tethered cord: outcome and follow-up of 20 de-thetering for symptomatic spina bifida: choort study. 复发性脐带拴系:20 例症状性脊柱裂去势手术的结果和随访:Choort 研究。
IF 1.3 4区 医学
Child's Nervous System Pub Date : 2024-11-01 Epub Date: 2024-07-17 DOI: 10.1007/s00381-024-06537-y
Vitoria Cristina de Almeida, Mila Torii Correa Leite, Patricia Alessandra Dastoli, Rodrigo Akira Watanabe, Nelci Zanon
{"title":"Recurrent tethered cord: outcome and follow-up of 20 de-thetering for symptomatic spina bifida: choort study.","authors":"Vitoria Cristina de Almeida, Mila Torii Correa Leite, Patricia Alessandra Dastoli, Rodrigo Akira Watanabe, Nelci Zanon","doi":"10.1007/s00381-024-06537-y","DOIUrl":"10.1007/s00381-024-06537-y","url":null,"abstract":"<p><strong>Objective: </strong>The objective of this study was to evaluate the prevalence of tethered cord among patients in the postoperative period of open and occult spina bifida. To identify warning signs for its early diagnosis, as well as outcomes after the new surgical approach.</p><p><strong>Methods: </strong>Retrospective study of patients followed at the Pediatric Neurosurgery Department of the Federal University of São Paulo with spinal dysraphism. Signs and symptoms indicating reoperation were collected, and postoperative results were classified as improved, unchanged, or worsened.</p><p><strong>Results: </strong>222 medical records of patients diagnosed with spinal dysraphism were evaluated. Symptomatic Tethered Cord Syndrome (STCS) was identified in 30 patients (13.51%), with clinical manifestations related to orthopedic deformities (66.7%), neurological deficits (56.7%), urological dysfunction (50%), and intestinal dysfunction (40%). 20 cases underwent surgery for tethered cord release. The mean age at the time of surgery was 7.7 ± 4.9 years, with 13 female patients (65%). In the postoperative evaluation, improvement in low back pain (90.9%), urological pattern, and urinary tract infection episodes (45.4%) were particularly noteworthy. 3 patients (33.3%) with constipation showed improvement, and one worsened (11.1%). Improvement in ambulation was seen in two cases (16.7%). Low back pain was the first symptom to improve after surgery, with an average time of 1.3 months, followed by changes in the urological pattern at 15.6 months. Improvement in constipation was observed in the first month in 2 cases (66.7%), positive changes in ambulation were observed around 7 months after surgery, and only one case showed improvement in clubfoot correction.</p><p><strong>Conclusions: </strong>The prevalence of tethered cord recurrence after primary correction surgery for open or occult neural tube closure defects was similar to that found in the literature. The results were encouraging, with good postoperative evolution of patients, especially in the improvement of low back pain and urological symptoms.</p>","PeriodicalId":9970,"journal":{"name":"Child's Nervous System","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141626194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transcranial motor-evoked potentials disappear with pons transection. 脑桥横断后,经颅运动诱发电位消失。
IF 1.3 4区 医学
Child's Nervous System Pub Date : 2024-11-01 Epub Date: 2024-08-21 DOI: 10.1007/s00381-024-06575-6
Ryota Sasaki, Tae Kyun Kim, Tsunenori Takatani, Young-Soo Park, Ichiro Nakagawa
{"title":"Transcranial motor-evoked potentials disappear with pons transection.","authors":"Ryota Sasaki, Tae Kyun Kim, Tsunenori Takatani, Young-Soo Park, Ichiro Nakagawa","doi":"10.1007/s00381-024-06575-6","DOIUrl":"10.1007/s00381-024-06575-6","url":null,"abstract":"<p><p>Motor-evoked potential (MEP) monitoring by transcranial electrical stimulation (TES) is important for intraoperative motor function assessment in neurosurgery; however, false-negative results sometimes occur, and these findings should be interpreted with caution. Herein, we report an interesting MEP change resulting from a pons transection. The patient was a boy aged 5 years and 2 months. He underwent multiple craniotomies for cerebellar anaplastic ependymoma and was already paralyzed in the right upper and lower limbs. Therefore, we decided to remove the recurrent lesion from the left anterior pons. MEPs were recorded on both the right and left sides after the start of surgery but disappeared 1 h 30 min after the start of surgery in the TES on the operative side, even when the stimulation intensity was increased. The contralateral TES consistently recorded stable MEPs throughout the surgery. The tumor was completely resected on imaging. Immediately postoperatively, the patient experienced flaccid paralysis on the right side of the body, which recovered to preoperative levels over time. A transcranial MEP cannot be derived if the corticospinal tract is transected at the pons. Transcranial MEP findings may accurately reflect the corticospinal tract function if the injury is caudal to the pons.</p>","PeriodicalId":9970,"journal":{"name":"Child's Nervous System","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142016411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stigma, seizure self-efficacy, and quality of life in children with epilepsy. 癫痫患儿的耻辱感、癫痫发作自我效能感和生活质量。
IF 1.3 4区 医学
Child's Nervous System Pub Date : 2024-11-01 Epub Date: 2024-08-30 DOI: 10.1007/s00381-024-06590-7
Seren Aydin, Gökçen Öz Tunçer, Şeyma Genç, Gülbahar Kurt Bayir, Ayşe Aksoy
{"title":"Stigma, seizure self-efficacy, and quality of life in children with epilepsy.","authors":"Seren Aydin, Gökçen Öz Tunçer, Şeyma Genç, Gülbahar Kurt Bayir, Ayşe Aksoy","doi":"10.1007/s00381-024-06590-7","DOIUrl":"10.1007/s00381-024-06590-7","url":null,"abstract":"<p><strong>Introduction: </strong>In addition to seizure care, it has been well-established that a holistic approach to the treatment of children with epilepsy that addresses the social, behavioral, and psychological dimensions also benefits their quality of life (QoL). The aim of this study was to investigate the patient and parental perceived stigma, seizure self-efficacy of children with epilepsy, and the relationship with quality of life in terms of sociodemographic and epilepsy-related factors.</p><p><strong>Method: </strong>The study group consisted of children, aged between 8 and 18 years and with a diagnosis of epilepsy of at least six months duration and their parents. Pediatric Quality of Life Inventory (PedsQL), Child-Parent Stigma Scales, and the Seizure Self-Efficacy Scale for Children (SSES-C) were used for evaluation.</p><p><strong>Results: </strong>One hundred and forty-four children (mean age 12.6 ± 2.9 years) took part, of whom 48.6% were female. The mean Child Stigma Scale score was 1.77 ± 0.82, Parent Stigma Scale score 2.41 ± 0.75, SSES-C score was 3.37 ± 0.98, and PedsQL score was 72.8 ± 18.6 for children self-reports (CsR) and 73.2 ± 18.8 for parent proxy-reports. The intraclass correlation coefficient for parent-child PedsQL indicated a good level of agreement. There was a significant negative correlation between the Child Stigma Scale and the PedsQL-CsR scores. A significant positive correlation was identified between the SSES-C scores and the PedsQL-CsR scores.</p><p><strong>Discussion: </strong>Perceptions of stigma in children with epilepsy and their parents were high in this study population. Of note, the elevated stigma perception reported by the patients had a detrimental impact on seizure self-efficacy. This relationship may affect the children's QoL and further complicates epilepsy management in this patient group.</p>","PeriodicalId":9970,"journal":{"name":"Child's Nervous System","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142104809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intraoperative cone-beam computed tomography for catheter placement verification in pediatric hydrocephalus: technical note. 用于验证小儿脑积水导管位置的术中锥形束计算机断层扫描:技术说明。
IF 1.3 4区 医学
Child's Nervous System Pub Date : 2024-11-01 Epub Date: 2024-09-04 DOI: 10.1007/s00381-024-06592-5
Matthias Krause, Jasmina Lagumdzija, Simon Enzinger, Jörn Wittig, Alexander Gaggl, Roman P Metzger, Christoph J Griessenauer
{"title":"Intraoperative cone-beam computed tomography for catheter placement verification in pediatric hydrocephalus: technical note.","authors":"Matthias Krause, Jasmina Lagumdzija, Simon Enzinger, Jörn Wittig, Alexander Gaggl, Roman P Metzger, Christoph J Griessenauer","doi":"10.1007/s00381-024-06592-5","DOIUrl":"10.1007/s00381-024-06592-5","url":null,"abstract":"<p><p>Ventriculoperitoneal (VP) shunt placement, essential for managing hydrocephalus, often risks catheter malpositioning, especially in patients with small ventricles. We present a novel technique combining neuronavigation with intraoperative cone-beam computed tomography using the BrainLab system and Loop-X mobile imaging unit. This approach enables real-time verification of catheter placement by integrating preoperative MRI data with intraoperative CT imaging. In a 12-year-old boy with therapy-refractory idiopathic intracranial hypertension, neuronavigation was guided by the BrainLab Skull Fix and Cushing canula, ensuring precise catheter insertion into the right frontal horn. Post-placement, Loop-X facilitated immediate verification of the catheter's trajectory and positioning, corroborated by postoperative MRI. This technique demonstrated high precision and minimized radiation exposure, emphasizing its utility in reducing revision rates due to suboptimal catheter placement.</p>","PeriodicalId":9970,"journal":{"name":"Child's Nervous System","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11538199/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142124977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biobank for craniosynostosis and faciocraniosynostosis, rare pediatric congenital craniofacial disorders: a study protocol. 罕见小儿先天性颅面疾病--颅骨畸形症和面颅骨畸形症生物数据库:研究方案。
IF 1.3 4区 医学
Child's Nervous System Pub Date : 2024-11-01 Epub Date: 2024-08-12 DOI: 10.1007/s00381-024-06555-w
Lucia De Martino, Peppino Mirabelli, Lucia Quaglietta, Ursula Pia Ferrara, Stefania Picariello, Domenico Vincenzo De Gennaro, Marco Aiello, Giovanni Smaldone, Ferdinando Aliberti, Pietro Spennato, Daniele De Brasi, Eugenio Covelli, Giuseppe Cinalli
{"title":"Biobank for craniosynostosis and faciocraniosynostosis, rare pediatric congenital craniofacial disorders: a study protocol.","authors":"Lucia De Martino, Peppino Mirabelli, Lucia Quaglietta, Ursula Pia Ferrara, Stefania Picariello, Domenico Vincenzo De Gennaro, Marco Aiello, Giovanni Smaldone, Ferdinando Aliberti, Pietro Spennato, Daniele De Brasi, Eugenio Covelli, Giuseppe Cinalli","doi":"10.1007/s00381-024-06555-w","DOIUrl":"10.1007/s00381-024-06555-w","url":null,"abstract":"<p><strong>Purpose: </strong>Craniosynostosis (CRS) is a rare congenital cranial malformation in which 1 or more cranial or facial sutures are fused in utero or rapidly fused in early infancy. The cranial sutures separate the skull bone plates and enable rapid growth of the skull in the first 2 years of life, in which growth is largely dictated by growth of the brain. CRS is a rare disease that occurs in 1 in 2100 to 1 in 2500 births and may be either nonsyndromic (also referred to as isolated) or syndromic. In syndromic CRS, other birth defects are present next to the CRS. The distinction between nonsyndromic and syndromic manifestations is made on the basis of dysmorphologic evaluation and genetic evaluation. Owing to advances in genetic diagnostics, nonsyndromic patients are increasingly recognized as syndromic patients. CRS treatment is almost entirely surgical and is sometimes paired with postoperative helmet therapy for maintenance. Corrective procedures are complex, long, and associated with the risk of numerous complications, including heavy blood loss and its sequelae. Although surgery may restore a normal appearance, even in nonsyndromic patients, patients may experience persistent deficits in intellectual ability and cognitive function. The European Commission (EC) has prioritized rare diseases in recent horizon European research programs; indeed, collections or even individual samples may be extremely valuable for research.</p><p><strong>Methods and results: </strong>Here, we present a study protocol in which the combined expertise of clinicians and researchers will be exploited to generate a biobank dedicated to CRS. The generation of the CRS biobank presented in this study will include the collection of different types of biological materials as well as advanced radiological images available to the scientific community.</p><p><strong>Conclusion: </strong>The activation of a CRS biobank will provide an opportunity to improve translational research on CRS and to share its benefits with the scientific community and patients and their families.</p>","PeriodicalId":9970,"journal":{"name":"Child's Nervous System","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11538127/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141916196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Regression of Chiari malformation type 2 following early postnatal meningomyelocele repair-a retrospective observation from an institutional series of patients. 产后早期脑膜瘢痕修复术后Chiari畸形2型的消退--机构系列患者的回顾性观察。
IF 1.3 4区 医学
Child's Nervous System Pub Date : 2024-11-01 Epub Date: 2024-08-29 DOI: 10.1007/s00381-024-06586-3
Radek Frič, Mona Kristiansen Beyer, Bernt Johan Due-Tønnessen
{"title":"Regression of Chiari malformation type 2 following early postnatal meningomyelocele repair-a retrospective observation from an institutional series of patients.","authors":"Radek Frič, Mona Kristiansen Beyer, Bernt Johan Due-Tønnessen","doi":"10.1007/s00381-024-06586-3","DOIUrl":"10.1007/s00381-024-06586-3","url":null,"abstract":"<p><strong>Purpose: </strong>Spontaneous regression of Chiari malformation type 2 (CM2) is observed rarely, as CM2 is associated with meningomyelocele (MMC) that is surgically repaired either pre- or early postnatally. While the radiological regression of CM2 occurs frequently following prenatal repair of MMC, it has been reported in only a few studies after postnatal repair.</p><p><strong>Methods: </strong>From the consecutive series of children with postnatally repaired MMC, we reviewed the clinical and radiological data regarding CM2, particularly its regression either spontaneously or following CSF diversion.</p><p><strong>Results: </strong>Eighteen children underwent postnatal repair of MMC between February 2011 and April 2023. CM2 was present in 16 (89%), and hydrocephalus in 15 children (83%), requiring shunting in 14 of them. During the mean clinical observation time (from birth to April 2023) of 59 ± 51 months, three children with CM2 (19%) underwent 1-2 foramen magnum decompressions (FMD), five children (28%) 1-4 surgical untethering procedures and 13 children with shunted hydrocephalus (93%) 1-5 shunt revisions. Out of sixteen children with CM2, we observed regression of CM2 on MRI in only one case (6%) during the mean radiological follow-up (from birth to the last MRI taken) of 49 ± 51 months.</p><p><strong>Conclusion: </strong>In our experience, spontaneous regression of CM2 in children with postnatally repaired MMC occurs quite rarely. Pathophysiological mechanisms behind the development of CM2 in children with MMC remain unclear, but our observation supports the hypothesis of an association between the downward displacement of the hindbrain and the low intraspinal pressure secondary to CSF leakage in children born with MMC.</p>","PeriodicalId":9970,"journal":{"name":"Child's Nervous System","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11538272/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142104808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Peripheral nerve injuries associated with dislocated supracondylar fractures of distal humerus in children: incidence and need of surgical treatment. 与儿童肱骨远端髁上骨折脱位相关的周围神经损伤:发生率和手术治疗的必要性。
IF 1.3 4区 医学
Child's Nervous System Pub Date : 2024-11-01 Epub Date: 2024-06-18 DOI: 10.1007/s00381-024-06497-3
Robert Chrenko, Martin Hanko, Marek Grega, Ľubomír Sýkora, René Jáger
{"title":"Peripheral nerve injuries associated with dislocated supracondylar fractures of distal humerus in children: incidence and need of surgical treatment.","authors":"Robert Chrenko, Martin Hanko, Marek Grega, Ľubomír Sýkora, René Jáger","doi":"10.1007/s00381-024-06497-3","DOIUrl":"10.1007/s00381-024-06497-3","url":null,"abstract":"<p><strong>Purpose: </strong>The objective of this study was to determine the incidence, necessity for neurosurgical intervention, and overall results of the treatment of pediatric peripheral nerve injuries associated with dislocated supracondylar fractures of the distal humerus.</p><p><strong>Method: </strong>A retrospective analysis of pediatric patients with supracondylar fractures treated from April 2019 to April 2022 with a minimum follow-up of 3 months was conducted.</p><p><strong>Results: </strong>Of 453 included patients, there were 51 recorded peripheral nerve injuries. The ulnar nerve was the most frequently injured nerve. Nine patients required neurosurgical intervention, with the most common procedure being the release of entrapped nerves. The combination of a supracondylar fracture and arterial injury was identified as a significant risk factor for peripheral nerve injury (p < 0.001). Only one patient experienced an unsatisfactory outcome.</p><p><strong>Conclusion: </strong>Although the prognosis for peripheral nerve injuries in children with supracondylar fractures is generally favorable, these injuries must be properly identified. We recommend an active neurosurgical approach in children with persisting neurological deficits to minimize the risk of permanent neurological impairment.</p>","PeriodicalId":9970,"journal":{"name":"Child's Nervous System","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141418085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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