Clinical manifestations, imaging characteristics, and surgical outcome of cervical spinal osteochondroma in pediatrics patients: a case base systematic review of an unusual tumor.
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引用次数: 0
Abstract
Purpose: Pediatric spinal osteochondroma is a rare, benign tumor that can be challenging to diagnose and treat, particularly in the cervical spine. This study aimed to explore the imaging characteristics, clinical manifestations, and surgical techniques used for these tumors in pediatric patients by compiling all reported cases of cervical osteochondroma.
Research question: Furthermore, it aims to analyze the outcomes of laminectomy with excised cervical osteochondroma in children, with an additional case report from the authors' experience.
Methods: A systematic search was conducted across PubMed, Scopus, and Web of Science using specific keywords related to pediatric osteochondroma. Following PRISMA guidelines, titles and abstracts were screened, and a comprehensive full-text review was conducted for the remaining articles. The findings were organized into tables and analyzed using descriptive statistics, including means, standard deviations, and percentages with 95% confidence intervals.
Results: We identified 201 articles, of which 38, reporting 43 cases, were included. Patients had a mean age of 12 years (SD ± 3.80 years) at presentation, with 55% being males. The majority presented with solitary osteochondroma (53%), predominantly located posteriorly (41 cases). The most common lesion level was C2 (13 cases). The most frequent clinical manifestation was pyramidal syndrome (60%). Laminectomy was the most commonly used surgical technique (67%). Post-surgery, 79% of patients showed full recovery, with hemilaminectomy associated with one case of recurrence.
Conclusion: Laminectomy has emerged as the predominant treatment modality, demonstrating minimal complications and high success rates with low recurrence. However, personalized treatment plans are essential to address the anatomical and clinical variability of these tumors.
目的：小儿脊柱骨软骨瘤是一种罕见的良性肿瘤，诊断和治疗具有挑战性，特别是在颈椎。本研究旨在通过汇总所有颈椎骨软骨瘤的报告病例，探讨小儿颈椎骨软骨瘤的影像学特征、临床表现和手术技术。研究问题：此外，它的目的是分析儿童颈椎骨软骨瘤切除椎板切除术的结果，并从作者的经验中获得额外的病例报告。方法：系统检索PubMed、Scopus和Web of Science，使用与儿童骨软骨瘤相关的特定关键词。按照PRISMA的指导方针，对标题和摘要进行了筛选，并对其余文章进行了全面的全文审查。研究结果被组织成表格，并使用描述性统计进行分析，包括平均值、标准差和95%置信区间的百分比。结果：我们纳入201篇文章，其中38篇报道了43例病例。患者就诊时平均年龄为12岁（SD±3.80岁），其中55%为男性。大多数表现为孤立性骨软骨瘤（53%），主要位于后侧（41例）。最常见的病变级别为C2（13例）。最常见的临床表现为锥体综合征（60%）。椎板切除术是最常用的手术技术（67%）。术后，79%的患者完全恢复，半椎板切除术后有一例复发。结论：椎板切除术已成为主要的治疗方式，并发症少，成功率高，复发率低。然而，个性化的治疗计划对于解决这些肿瘤的解剖和临床变异性至关重要。
期刊介绍：
The journal has been expanded to encompass all aspects of pediatric neurosciences concerning the developmental and acquired abnormalities of the nervous system and its coverings, functional disorders, epilepsy, spasticity, basic and clinical neuro-oncology, rehabilitation and trauma. Global pediatric neurosurgery is an additional field of interest that will be considered for publication in the journal.
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