IF 1.2 4区化学

Chimia Pub Date : 2024-03-27 DOI: 10.2533/chimia.2024.104

Simon Wagschal, Diego Broggini

引用次数: 0

Modeling-based Approach Towards Quality by Design for a Telescoped Process. 基于建模的方法，通过设计提高远程过程的质量。

IF 1.2 4区化学

Chimia Pub Date : 2024-03-27 DOI: 10.2533/chimia.2024.135

This Zahnd, Maja Kandziora, Michael K Levis, Andreas Zogg

引用次数: 0

Editorial. 社论

IF 1.2 4区化学

Chimia Pub Date : 2024-03-27

Lucie Lovelle

引用次数: 0

An Alternative Procedure for a Win-win African-Swiss Cooperation in Gold Production in Africa. 非洲与瑞士在非洲黄金生产合作中实现双赢的替代程序。

IF 1.2 4区化学

Chimia Pub Date : 2024-03-27 DOI: 10.2533/chimia.2024.159

Aliyar Mousavi

{"title":"An Alternative Procedure for a Win-win African-Swiss Cooperation in Gold Production in Africa.","authors":"Aliyar Mousavi","doi":"10.2533/chimia.2024.159","DOIUrl":"10.2533/chimia.2024.159","url":null,"abstract":"The growth of Africa as a major gold (Au) exporter can not only strengthen economic ties with other parts of the world, but also lead to solutions to global industrial challenges, and the only way to stop gold smuggling out of gold-producing African countries seems to be having multiple refineries in Africa, for which developing gold-producing African countries might need technological assistance provided by a more developed country, especially Switzerland. In this Note, the chemistry of gold mining was discussed, and the idea is conveyed that if aqua regia is used as a main reagent in both gold mining and the electrolytic refinement of gold, then the two systems of gold mining and gold refining can be coupled industrially and geographically, and such a coupling can facilitate the growth of home-grown gold refineries in gold-producing African countries. It is also discussed that with Swiss companies finding it economical to properly use aqua regia in Africa as described, a win-win African-Swiss cooperation will be established that will benefit both the Swiss companies and gold-producing African countries. Further, it is concluded that the addressed cooperation will be accompanied by four of the seventeen goals called 'Sustainable Development Goals' by the United Nations.","PeriodicalId":9957,"journal":{"name":"Chimia","volume":"78 3","pages":"159-161"},"PeriodicalIF":1.2,"publicationDate":"2024-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140317885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Excelzyme: A Swiss University-Industry Collaboration for Accelerated Biocatalyst Development. Excelzyme：加速生物催化剂开发的瑞士产学合作项目。

IF 1.2 4区化学

Chimia Pub Date : 2024-03-27 DOI: 10.2533/chimia.2024.108

Sumire Honda Malca, Peter Stockinger, Nadine Duss, Daniela Milbredt, Hans Iding, Rebecca Buller

引用次数: 0

Interfacial Chemistry and Catalysis of Inorganic Materials. 无机材料的界面化学与催化。

IF 1.2 4区化学

Chimia Pub Date : 2024-02-28 DOI: 10.2533/chimia.2024.7

Tzu-Chin Chang Chien, Murielle F Delley

引用次数: 0

Capturing the Chirality of Photoexcited States with Ultrafast Circular Dichroism. 利用超快圆二色性捕捉光激发态的手性。

IF 1.2 4区化学

Chimia Pub Date : 2024-02-28 DOI: 10.2533/chimia.2024.45

Malte Oppermann

{"title":"Capturing the Chirality of Photoexcited States with Ultrafast Circular Dichroism.","authors":"Malte Oppermann","doi":"10.2533/chimia.2024.45","DOIUrl":"https://doi.org/10.2533/chimia.2024.45","url":null,"abstract":"Chiral molecules exist in two forms, called enantiomers, which are mirror images of each other but non-superimposable. Even though enantiomers share most chemical and physical properties, they may differ greatly in their (bio-)chemical activities, which turns chirality into a key design feature for (bio-)chemical function. In this spirit, the incorporation of chiral structures into photochemical systems has emerged as a powerful strategy to control their functions. For example, uni-directional molecular motors, chiral photocatalysts, and chiral metal nanostructures permit new levels of stereocontrol over mechanical motion, energy transfer, and electric charge-carriers on the nanoscale. However, the direct characterization of the underlying chiral photoexcited states remains a formidable experimental challenge - especially in the native solution phase of many photochemical processes. Crucially, this requires analytical techniques that combine a high chiral sensitivity in solution with ultrafast time resolution to capture the excited state dynamics. This brief perspective article presents recent progress in the development of ultrafast chiral spectroscopy techniques that address this challenge.","PeriodicalId":9957,"journal":{"name":"Chimia","volume":"78 1-2","pages":"45-49"},"PeriodicalIF":1.2,"publicationDate":"2024-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140012320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Editorial. 社论

IF 1.2 4区化学

Chimia Pub Date : 2024-02-28

Catherine Housecroft

引用次数: 0

Electron-Transferring Metalloenzymes and their Potential Biotechnological Applications. 电子转移金属酶及其潜在的生物技术应用。

IF 1.2 4区化学

Chimia Pub Date : 2024-02-28 DOI: 10.2533/chimia.2024.13

Ross D Milton

{"title":"Electron-Transferring Metalloenzymes and their Potential Biotechnological Applications.","authors":"Ross D Milton","doi":"10.2533/chimia.2024.13","DOIUrl":"10.2533/chimia.2024.13","url":null,"abstract":"Modern societies rely heavily on centralized industrial processes to generate a multitude of products ranging from electrical energy to synthetic chemical building blocks to construction materials. To date, these processes have relied extensively on energy produced from fossil fuels, which has led to dramatically increased quantities of greenhouse gases (including carbon dioxide) being released into the atmosphere; the effects of the ensuing change to our climate are easily observed in day-to-day life. Some of the reactions catalyzed by these industrial processes can be catalyzed in nature by metal-containing enzymes (metalloenzymes) that have evolved over the course of up to 3.8 billion years to do so under mild physiological conditions using Earth-abundant metals. While such metalloenzymes could in principle facilitate the implementation of carbon-neutral processes around the globe, either in \"bio-inspired\" catalyst design or even by direct exploitation, many remaining questions surrounding their mechanisms often preclude both options. Here, our recent efforts in understanding and applying metalloenzymes that catalyze reactions such as dinitrogen reduction to ammonia or proton reduction to molecular hydrogen are discussed. In closing, an opinion on the question: \"Can these types of enzymes really be used in new biotechnologies?\" is offered.","PeriodicalId":9957,"journal":{"name":"Chimia","volume":"78 1-2","pages":"13-21"},"PeriodicalIF":1.2,"publicationDate":"2024-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140012322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Practical Approaches to Genetic Code Expansion with Aminoacyl-tRNA Synthetase/tRNA Pairs. 利用氨基酰-tRNA 合成酶/tRNA 对扩展遗传密码的实用方法。

IF 1.2 4区化学

Chimia Pub Date : 2024-02-28 DOI: 10.2533/chimia.2024.22

Anton Natter Perdiguero, Alexandria Deliz Liang

{"title":"Practical Approaches to Genetic Code Expansion with Aminoacyl-tRNA Synthetase/tRNA Pairs.","authors":"Anton Natter Perdiguero, Alexandria Deliz Liang","doi":"10.2533/chimia.2024.22","DOIUrl":"10.2533/chimia.2024.22","url":null,"abstract":"Genetic code expansion (GCE) can enable the site-selective incorporation of non-canonical amino acids (ncAAs) into proteins. GCE has advanced tremendously in the last decade and can be used to create biorthogonal handles, monitor and control proteins inside cells, study post-translational modifications, and engineer new protein functions. Since establishing our laboratory, our research has focused on applications of GCE in protein and enzyme engineering using aminoacyl-tRNA synthetase/tRNA (aaRS/tRNA) pairs. This topic has been reviewed extensively, leaving little doubt that GCE is a powerful tool for engineering proteins and enzymes. Therefore, for this young faculty issue, we wanted to provide a more technical look into the methods we use and the challenges we think about in our laboratory. Since starting the laboratory, we have successfully engineered over a dozen novel aaRS/tRNA pairs tailored for various GCE applications. However, we acknowledge that the field can pose challenges even for experts. Thus, herein, we provide a review of methodologies in ncAA incorporation with some practical commentary and a focus on challenges, emerging solutions, and exciting developments.","PeriodicalId":9957,"journal":{"name":"Chimia","volume":"78 1-2","pages":"22-31"},"PeriodicalIF":1.2,"publicationDate":"2024-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140012285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

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