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Heat acclimation in mice requires preoptic BDNF neurons and postsynaptic potentiation
IF 44.1 1区 生物学
Cell Research Pub Date : 2024-12-26 DOI: 10.1038/s41422-024-01064-6
Baoting Chen, Cuicui Gao, Changhao Liu, Tongtong Guo, Junwei Hu, Jialiang Xue, Kangmin Tang, Yuelai Chen, Tian Yu, Qiwei Shen, Hongbin Sun, Wen Z. Yang, Wei L. Shen
{"title":"Heat acclimation in mice requires preoptic BDNF neurons and postsynaptic potentiation","authors":"Baoting Chen, Cuicui Gao, Changhao Liu, Tongtong Guo, Junwei Hu, Jialiang Xue, Kangmin Tang, Yuelai Chen, Tian Yu, Qiwei Shen, Hongbin Sun, Wen Z. Yang, Wei L. Shen","doi":"10.1038/s41422-024-01064-6","DOIUrl":"https://doi.org/10.1038/s41422-024-01064-6","url":null,"abstract":"<p>Dear Editor,</p>","PeriodicalId":9926,"journal":{"name":"Cell Research","volume":"14 1","pages":""},"PeriodicalIF":44.1,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142886727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Astrocytes: emerging stars of engrams
IF 44.1 1区 生物学
Cell Research Pub Date : 2024-12-23 DOI: 10.1038/s41422-024-01066-4
Sofiya Zbaranska, Sheena A. Josselyn
{"title":"Astrocytes: emerging stars of engrams","authors":"Sofiya Zbaranska, Sheena A. Josselyn","doi":"10.1038/s41422-024-01066-4","DOIUrl":"https://doi.org/10.1038/s41422-024-01066-4","url":null,"abstract":"<p><b>During learning experience, a subset of astrocytes in the hippocampus is activated and becomes both necessary and sufficient for subsequent memory recall. Williamson et al. discovered that these learning-associated astrocytes play an important role in memory by modulating engram neurons’ synaptic activity and facilitating the reactivation of engram neuron ensembles during memory retrieval</b>.</p>","PeriodicalId":9926,"journal":{"name":"Cell Research","volume":"113 1","pages":""},"PeriodicalIF":44.1,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142873913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tug of war between phosphatase and kinase during sleep
IF 44.1 1区 生物学
Cell Research Pub Date : 2024-12-20 DOI: 10.1038/s41422-024-01065-5
Niels Niethard, Jan Born
{"title":"Tug of war between phosphatase and kinase during sleep","authors":"Niels Niethard, Jan Born","doi":"10.1038/s41422-024-01065-5","DOIUrl":"https://doi.org/10.1038/s41422-024-01065-5","url":null,"abstract":"<p><b>In a recent work published in</b> <b><i>Nature</i></b><b>, Wang et al. reveal how protein kinase A and calcineurin dynamically regulate the daily duration of sleep and wake periods at excitatory post-synapses in the brain. This study uncovers key molecular mechanisms offering new insights into the enzymatic control of sleep homeostasis.</b></p>","PeriodicalId":9926,"journal":{"name":"Cell Research","volume":"10 1","pages":""},"PeriodicalIF":44.1,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142857716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction: Sanofi-Cell Research outstanding paper award of 2023
IF 44.1 1区 生物学
Cell Research Pub Date : 2024-12-12 DOI: 10.1038/s41422-024-01062-8
{"title":"Correction: Sanofi-Cell Research outstanding paper award of 2023","authors":"","doi":"10.1038/s41422-024-01062-8","DOIUrl":"https://doi.org/10.1038/s41422-024-01062-8","url":null,"abstract":"<p>Correction to: <i>Cell Research</i> https://doi.org/10.1038/s41422-024-01056-6, published online 26 November 2024</p>","PeriodicalId":9926,"journal":{"name":"Cell Research","volume":"7 1","pages":""},"PeriodicalIF":44.1,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142809696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Photoactivated SOPP3 enables APEX2-mediated proximity labeling with high spatio-temporal resolution in live cells
IF 44.1 1区 生物学
Cell Research Pub Date : 2024-12-10 DOI: 10.1038/s41422-024-01061-9
Dajun Qu, Yaxin Li, Qian Liu, Biao Cao, Mengye Cao, Xiaoxi Lin, Chengxing Shen, Peng Zou, Hu Zhou, Wenjuan Zhang, Weijun Pan
{"title":"Photoactivated SOPP3 enables APEX2-mediated proximity labeling with high spatio-temporal resolution in live cells","authors":"Dajun Qu, Yaxin Li, Qian Liu, Biao Cao, Mengye Cao, Xiaoxi Lin, Chengxing Shen, Peng Zou, Hu Zhou, Wenjuan Zhang, Weijun Pan","doi":"10.1038/s41422-024-01061-9","DOIUrl":"https://doi.org/10.1038/s41422-024-01061-9","url":null,"abstract":"","PeriodicalId":9926,"journal":{"name":"Cell Research","volume":"213 1","pages":""},"PeriodicalIF":44.1,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142797105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Triaptosis: an endosome-dependent cell death modality
IF 44.1 1区 生物学
Cell Research Pub Date : 2024-12-06 DOI: 10.1038/s41422-024-01053-9
Daolin Tang, Rui Kang, Guido Kroemer
{"title":"Triaptosis: an endosome-dependent cell death modality","authors":"Daolin Tang, Rui Kang, Guido Kroemer","doi":"10.1038/s41422-024-01053-9","DOIUrl":"https://doi.org/10.1038/s41422-024-01053-9","url":null,"abstract":"<p><b>Recent research published in</b> <b><i>Science</i></b> <b>reveals that menadione, a precursor to vitamin K, induces a unique cell death pathway called triaptosis by oxidizing phosphatidylinositol 3-kinase PIK3C3/VPS34. This oxidation leads to endosomal dysfunction, highlighting how excessive oxidative stress can compromise cellular structures and activate specific cell death pathways</b>.</p>","PeriodicalId":9926,"journal":{"name":"Cell Research","volume":"17 1","pages":""},"PeriodicalIF":44.1,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142782549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Encoding immune responses: the moonlighting function of alanyl-tRNA synthetase.
IF 28.1 1区 生物学
Cell Research Pub Date : 2024-11-28 DOI: 10.1038/s41422-024-01055-7
Pin Wang, Xiaoyu Hu
{"title":"Encoding immune responses: the moonlighting function of alanyl-tRNA synthetase.","authors":"Pin Wang, Xiaoyu Hu","doi":"10.1038/s41422-024-01055-7","DOIUrl":"https://doi.org/10.1038/s41422-024-01055-7","url":null,"abstract":"","PeriodicalId":9926,"journal":{"name":"Cell Research","volume":" ","pages":""},"PeriodicalIF":28.1,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142750030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sanofi-Cell Research outstanding paper award of 2023 赛诺菲-细胞研究 2023 年度优秀论文奖
IF 28.1 1区 生物学
Cell Research Pub Date : 2024-11-26 DOI: 10.1038/s41422-024-01056-6
Cell Research Editorial Team
{"title":"Sanofi-Cell Research outstanding paper award of 2023","authors":"Cell Research Editorial Team","doi":"10.1038/s41422-024-01056-6","DOIUrl":"10.1038/s41422-024-01056-6","url":null,"abstract":"","PeriodicalId":9926,"journal":{"name":"Cell Research","volume":"34 12","pages":"817-817"},"PeriodicalIF":28.1,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41422-024-01056-6.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142713039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stressing out the intestinal microbiota via a brain-neuroglandular circuit. 通过大脑-神经-腺体回路给肠道微生物群施压
IF 28.1 1区 生物学
Cell Research Pub Date : 2024-11-26 DOI: 10.1038/s41422-024-01047-7
Wen Zhang, David Artis
{"title":"Stressing out the intestinal microbiota via a brain-neuroglandular circuit.","authors":"Wen Zhang, David Artis","doi":"10.1038/s41422-024-01047-7","DOIUrl":"https://doi.org/10.1038/s41422-024-01047-7","url":null,"abstract":"","PeriodicalId":9926,"journal":{"name":"Cell Research","volume":" ","pages":""},"PeriodicalIF":28.1,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142725840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A GSDMD agonist boosts specific antitumor immunity 一种 GSDMD 激动剂能增强特异性抗肿瘤免疫力
IF 44.1 1区 生物学
Cell Research Pub Date : 2024-11-13 DOI: 10.1038/s41422-024-01051-x
Yingying Zhang, Jiahuai Han
{"title":"A GSDMD agonist boosts specific antitumor immunity","authors":"Yingying Zhang, Jiahuai Han","doi":"10.1038/s41422-024-01051-x","DOIUrl":"https://doi.org/10.1038/s41422-024-01051-x","url":null,"abstract":"<p><b>The beneficial role of gasdermin activation and pyroptosis induction in antitumor immunity has been implicated by several studies; however, the question of how to specifically and efficiently activate cancer cell death while minimizing toxicity to host cells remains unsolved. In a recent paper published in</b> <b><i>Cell</i></b><b>, Wu and Lieberman groups identified a GSDMD agonist that can induce low-level pyroptosis in cancer cells but not in host cells, offering potential applications in cancer vaccine development and therapy in combination with checkpoint blockade</b>.</p>","PeriodicalId":9926,"journal":{"name":"Cell Research","volume":"41 1","pages":""},"PeriodicalIF":44.1,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142600988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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