Photochemical & Photobiological Sciences最新文献

{"title":"Environmental consequences of interacting effects of changes in stratospheric ozone, ultraviolet radiation, and climate: UNEP Environmental Effects Assessment Panel, Update 2024.","authors":"Patrick J Neale, Samuel Hylander, Anastazia T Banaszak, Donat-P Häder, Kevin C Rose, Davide Vione, Sten-Åke Wängberg, Marcel A K Jansen, Rosa Busquets, Mads P Sulbæk Andersen, Sasha Madronich, Mark L Hanson, Tamara Schikowski, Keith R Solomon, Barbara Sulzberger, Timothy J Wallington, Anu M Heikkilä, Krishna K Pandey, Anthony L Andrady, Laura S Bruckman, Christopher C White, Liping Zhu, Germar H Bernhard, Alkiviadis Bais, Pieter J Aucamp, Gabriel Chiodo, Raúl R Cordero, Irina Petropavlovskikh, Rachel E Neale, Catherine M Olsen, Simon Hales, Aparna Lal, Gareth Lingham, Lesley E Rhodes, Antony R Young, T Matthew Robson, Sharon A Robinson, Paul W Barnes, Janet F Bornman, Anna B Harper, Hanna Lee, Roy Mackenzie Calderón, Rachele Ossola, Nigel D Paul, Laura E Revell, Qing-Wei Wang, Richard G Zepp","doi":"10.1007/s43630-025-00687-x","DOIUrl":"10.1007/s43630-025-00687-x","url":null,"abstract":"<p><p>This Assessment Update by the Environmental Effects Assessment Panel (EEAP) of the United Nations Environment Programme (UNEP) addresses the interacting effects of changes in stratospheric ozone, solar ultraviolet (UV) radiation, and climate on the environment and human health. These include new modelling studies that confirm the benefits of the Montreal Protocol in protecting the stratospheric ozone layer and its role in maintaining a stable climate, both at low and high latitudes. We also provide an update on projected levels of solar UV-radiation during the twenty-first century. Potential environmental consequences of climate intervention scenarios are also briefly discussed, illustrating the large uncertainties of, for example, Stratospheric Aerosol Injection (SAI). Modelling studies predict that, although SAI would cool the Earth's surface, other climate factors would be affected, including stratospheric ozone depletion and precipitation patterns. The contribution to global warming of replacements for ozone-depleting substances (ODS) are assessed. With respect to the breakdown products of chemicals under the purview of the Montreal Protocol, the risks to ecosystem and human health from the formation of trifluoroacetic acid (TFA) as a degradation product of ODS replacements are currently de minimis. UV-radiation and climate change continue to have complex interactive effects on the environment due largely to human activities. UV-radiation, other weathering factors, and microbial action contribute significantly to the breakdown of plastic waste in the environment, and in affecting transport, fate, and toxicity of the plastics in terrestrial and aquatic ecosystems, and the atmosphere. Sustainability demands continue to drive industry innovations to mitigate environmental consequences of the use and disposal of plastic and plastic-containing materials. Terrestrial ecosystems in alpine and polar environments are increasingly being exposed to enhanced UV-radiation due to earlier seasonal snow and ice melt because of climate warming and extended periods of ozone depletion. Solar radiation, including UV-radiation, also contributes to the decomposition of dead plant material, which affects nutrient cycling, carbon storage, emission of greenhouse gases, and soil fertility. In aquatic ecosystems, loss of ice cover is increasing the area of polar oceans exposed to UV-radiation with possible negative effects on phytoplankton productivity. However, modelling studies of Arctic Ocean circulation suggests that phytoplankton are circulating to progressively deeper ocean layers with less UV irradiation. Human health is also modified by climate change and behaviour patterns, resulting in changes in exposure to UV-radiation with harmful or beneficial effects depending on conditions and skin type. For example, incidence of melanoma has been associated with increased air temperature, which affects time spent outdoors and thus exposure to UV-radiation. Overal","PeriodicalId":98,"journal":{"name":"Photochemical & Photobiological Sciences","volume":" ","pages":"357-392"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11971163/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143646428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The wound healing effects of linearly polarized irradiation in photobiomodulation.","authors":"You-Rim Park, Yoo-Kyoung Shin, Joo Beom Eom","doi":"10.1007/s43630-025-00696-w","DOIUrl":"10.1007/s43630-025-00696-w","url":null,"abstract":"<p><p>We report the fabrication of a polarization-based photobiomodulation (PBM) system and its performance on wound healing effects. The light source for PBM was a 625 nm LED and two different linear polarizations (P-wave and S-wave) were generated using the wire grid linear polarizers. To confirm the effect of PBM on polarization, wounds were created on hairless mice, and the healing process was compared. The light source conditions for comparison were control, two linearly polarized light, and unpolarized light. The light irradiation conditions for each group were based on the energy settings (energy 18 J/cm², power density 30 mW/cm², exposure time 600 sec) commonly used in LED masks. After creating the wound, the light was irradiated only once. To confirm the wound healing effect over time, it was evaluated through wound surface area measurements, self-made optical coherence tomography images, and histological images. In the group irradiated with S-wave polarized light, the percentage from the initial wound size was reduced to 70.73%, and the epithelial tongue ratio reached 58.36% on day 7 after PBM, indicating the fastest recovery. In this way, the potential of a new product that can increase the effect of wound healing or skin regeneration by adjusting the polarization state without irradiating high energy was confirmed.</p>","PeriodicalId":98,"journal":{"name":"Photochemical & Photobiological Sciences","volume":" ","pages":"417-428"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143571727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Baicalein prevents skin damage, tumorigenesis and tumor growth in chronic ultraviolet B-irradiated hairless mice.","authors":"Yoshiyuki Kimura, Maho Sumiyoshi, Masahiko Taniguchi","doi":"10.1007/s43630-025-00700-3","DOIUrl":"10.1007/s43630-025-00700-3","url":null,"abstract":"<p><p>Non-melanoma skin cancer accounted for over one million new cases, according to the Global Cancer Statistics 2020 report. Moreover, UV radiation causes photodamage (skin inflammation and angiogenesis), photoaging (increases in skin wrinkle and reduction in skin elasticity). This study investigated the preventive effects of baicalein against skin damage, aging, tumorigenesis and tumor growth in long-term UVB irradiated hairless mice. Five-week-old male mice were divided into the following groups: a non-UVB group (control), vehicle-treated UVB group (UVB control), and UVB groups treated with two different doses of baicalein (10 and 30 mg/kg, twice daily). The mice were exposed to UVB irradiation (36-192 mJ/cm²) three times per week for 23 weeks. Baicalein was orally administered at the specified doses for the same duration. Skin cytokine, chemokine, and vascular endothelial growth factor (VEGF) levels were measured using ELISA kits. Baicalein (at doses of 10 and 30 mg/kg) suppressed UVB-induced increases in skin thickness, improved skin elasticity, and reduced the number and growth of skin tumors. Additionally, baicalein inhibited UVB-induced increases in IL-1β, IL-6, MCP-1, MIF, VEGF, p53, COX-2, total/phospho-NF-κB expression levels in the skin. Immunohistochemical analysis revealed that baicalein attenuated UVB-induced increases in the number of Ki-67-, and HIF-1α-positive cells. The preventive effects of baicalein on skin damage and skin tumor growth in chronically UVB-irradiated mice were associated with reduced skin cytokine levels through the down-regulation of COX-2, phosphorylated NF-κB p65, and HIF-1α expression.</p>","PeriodicalId":98,"journal":{"name":"Photochemical & Photobiological Sciences","volume":" ","pages":"479-497"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143646426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A pyrene-based fluorescent probe for H₂S detection and cellular imaging.","authors":"Said Alam, Xuanzuo Tao, Yanxia Mao, Shaojun Zheng, Chunhui Jiang, Shu-Yang Chen, Hongfei Lu","doi":"10.1007/s43630-025-00695-x","DOIUrl":"10.1007/s43630-025-00695-x","url":null,"abstract":"<p><p>Hydrogen sulfide (H₂S) is a significant reactive sulfur species (RSS) involved in various human diseases, also playing an important role in many physiological and pathological processes. Thus, the development of an effective method for detecting H₂S in mammalian cells is of great importance. In this study, we present the synthesis of a novel pyrene-based fluorescent probe, DPP, specifically designed for the selective detection of H₂S. The DPP exhibits remarkable sensitivity, with a low detection limit of 0.63 µM, and demonstrates high selectivity for H₂S in the presence of various interfering species. Additionally, the probe has demonstrated rapid detection of H₂S in less than 6 min. The detection mechanism was thoroughly validated using ¹H NMR, FT-IR, UV and fluorescence spectra. Moreover, the applicability of DPP was successfully demonstrated in both in vitro and in vivo settings using HeLa cells, confirming its potential as a powerful tool for monitoring H₂S in biological systems. Additionally, the probe exhibited excellent performance in detecting H₂S in water samples and in paper strip-based assays, further highlighting its versatility and practical utility for environmental monitoring and on-site applications.</p>","PeriodicalId":98,"journal":{"name":"Photochemical & Photobiological Sciences","volume":" ","pages":"405-415"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143536238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Targeted photodynamic elimination of HER2 ⁺ breast cancer cells mediated by antibody-photosensitizer fusion proteins.","authors":"Yi Li, Jian Hou, Jun Wan, Qinglian Liu, Lei Zhou","doi":"10.1007/s43630-025-00689-9","DOIUrl":"10.1007/s43630-025-00689-9","url":null,"abstract":"<p><p>Breast cancer has emerged as the leading cause of cancer death in women worldwide. The high recurrence and metastasis rates of malignant tumors impose significant limitations on existing mainstream treatments, including surgery, chemotherapy, and radiotherapy. Photodynamic therapy (PDT) is a clinically validated approach for cancer treatment. PDT requires three elements, photosensitizer, light, and oxygen, and mainly relies on the production of singlet oxygen (¹O₂) to elicit damage to the cancer tissue. In this study, we explored targeted photodynamic elimination of breast cancer cells overexpressing human epidermal growth factor receptor 2 (HER2). HER2 is enriched on the surface of certain cancer cells and targeted by commercially available monoclonal antibodies, including Trastuzumab, in the treatment of breast and stomach cancers. We engineered chimeric fusion proteins composed of Trastuzumab and genetically encoded photosensitizers, including SOPP3 and miniSOG. The production of ¹O₂ by these fusion proteins was directly measured by near-infrared spectroscopy centered at 1270 nm and further evaluated in the assay of targeted photodynamic neutralizations of SARS-CoV-2 pseudoviruses. To enhance the internalization of the antibody-photosensitizer fusion protein, cell-penetrating peptides (CPPs) were added to the fusion protein. HER2-positive (HER2⁺) cancer cells were incubated with the antibody-photosensitizer fusion protein and then exposed to light illumination. Cell viability assays revealed an over 50% reduction in cancer cell survival, with minimal impacts on the cells from the control group. In addition, we observed a long-lasting, over 24-h inhibition of the growth of the cancer cells after photodynamic treatment. Thus, based on these assays at the molecular and cellular levels, this study established a targeted photodynamic approach that can potentially be developed as an effective PDT for cancer treatment.</p>","PeriodicalId":98,"journal":{"name":"Photochemical & Photobiological Sciences","volume":" ","pages":"393-403"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143584041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synergic anti-tumor effects of photodynamic therapy and resveratrol on triple-negative breast cancer cells.","authors":"Masta Ghazizadeh, Khatereh Khorsandi, SMahmoud A Najafi","doi":"10.1007/s43630-025-00698-8","DOIUrl":"10.1007/s43630-025-00698-8","url":null,"abstract":"<p><strong>Introduction: </strong>Breast cancer is a widespread type of cancer found across the world. The use of chemotherapy in breast cancer treatment may result in side effects and the emergence of drug resistance. Hence, seeking new and efficient therapies that reduce adverse reactions is imperative. Recently, combination therapy has emerged as a fresh and innovative strategy in contrast to conventional treatment methods. Photodynamic therapy (PDT) serves as a highly effective and minimally invasive technique for addressing breast cancer, providing the option to be utilized either concurrently or in conjunction with other therapeutic approaches. Resveratrol (RES) is a polyphenol found in several food sources. Research has demonstrated that RES can inhibit cell proliferation and metastasis and trigger apoptosis in tumor cells. This research aimed to assess the impact of combining RES and photodynamic therapy on MDA-MB-231 breast cancer cells.</p><p><strong>Methods: </strong>MDA-MB-231 cells were grown in culture and subsequently exposed to different methylene blue (MB) doses while subjected to laser irradiation (PDT). Following this treatment, the cells were exposed to different RES concentrations. Cell viability was assessed utilizing the MTT assay. Light and fluorescence microscopy (AO/EB staining) were employed to observe cell morphological alterations following exposure to RES and MB-PDT. Additionally, flow cytometry was utilized to investigate cell cycle progression and apoptosis induction.</p><p><strong>Results: </strong>The findings indicated that the co-administration of MB-PDT and RES resulted in increased cytotoxic effects on MDA-MB-231 breast cancer cells compared to the individual application of either treatment.</p><p><strong>Discussion: </strong>The results of this study suggest that MB-PDT can reduce the dose and time of RES treatment and, therefore, can be indicated as a new approach for treating breast cancer cells.</p>","PeriodicalId":98,"journal":{"name":"Photochemical & Photobiological Sciences","volume":" ","pages":"451-465"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143646381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Silk fibroin protein-templated gold nanoclusters for in vivo fluorescence imaging.","authors":"Shanshan He, Baozhu Wang, Huixin Hou, Yueyue Zhang, Zhijun Zhang, Feng Zhao, Miao Su","doi":"10.1007/s43630-025-00699-7","DOIUrl":"10.1007/s43630-025-00699-7","url":null,"abstract":"<p><p>Protein-templated synthesis has been proved to be an effective approach for building high-performance fluorescent bioimaging agents. Nevertheless, the high cost of proteins has restricted its wide application. Silk fibroin is a low cost natural protein with superior properties, which holds significant application prospects in many biomedical fields. However, its application potential in the biomedical imaging field remains to be explored. Herein, we report a one-pot green synthesis of high performance gold nanoclusters (AuNCs) using silk fibroin as stabilizer. The SF-AuNCs (~ 1.8 nm) shows a red emission around 600 nm with a large Stokes shift of 200 nm and a quantum yield of 5.42% which is comparable with that of fluorescence proteins. Meanwhile, the lifetime is as high as 3.47 μs which is about three magnitude orders higher than that of most molecular dyes and fluorescence proteins. Moreover, the stability is also greatly enhanced than that of the classical GSH-AuNCs. The SF-AuNCs is also well performed in cell labeling and in vivo imaging in zebrafish. This work not only provides a promising high performance protein fluorescence nano agent for bioimaging, but also expands the potential of the silk fibroin application in the biomedical imaging field.</p>","PeriodicalId":98,"journal":{"name":"Photochemical & Photobiological Sciences","volume":" ","pages":"467-477"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143668548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"UVA-light-induced mutagenesis in the exome of human nucleotide excision repair-deficient cells.","authors":"Nathalia Quintero-Ruiz, Camila Corradi, Natália Cestari Moreno, Tiago Antonio de Souza, Carlos Frederico Martins Menck","doi":"10.1007/s43630-025-00697-9","DOIUrl":"10.1007/s43630-025-00697-9","url":null,"abstract":"<p><p>Skin cancer is associated with genetic mutations caused by sunlight exposure, primarily through ultraviolet (UV) radiation that damages DNA. While UVA is less energetic, it is the predominant solar UV component reaching the Earth's surface. However, the mechanisms of UVA-induced mutagenesis and its role in skin cancer development remain poorly understood. This study employed whole exome sequencing of clones from human XP-C cells, which lack nucleotide excision repair (NER), to characterize somatic mutations induced by UVA exposure. DNA sequence analysis of UVA-irradiated XP-C cells revealed a marked increase in mutation frequency across nearly all types of base substitutions, with particular enrichment in C > T transitions within the CCN and TCN trinucleotide context-potential sites for pyrimidine dimer formation. The C > T mutation primarily occurred at the 3' base of the 5'TC dimer, and an enrichment of CC > TT tandem mutations. We also identified the SBS7b COSMIC mutational signature within irradiated cells, which has been associated with tumors in sun-exposed skin. C > A transversions, often linked to oxidized guanine, were the second most frequently induced mutation, although a specific context for this base substitution was not identified. Moreover, C > T mutations were significantly increased in unirradiated XP-C compared to NER-proficient cells, which may be caused by unrepaired spontaneous DNA damage. Thus, this study indicates that pyrimidine dimers are the primary lesions contributing to UVA-induced mutagenesis in NER-deficient human cells and demonstrates that UVA generates mutational signatures similar to those of UVB irradiation.</p>","PeriodicalId":98,"journal":{"name":"Photochemical & Photobiological Sciences","volume":" ","pages":"429-449"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143595881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TIMP3 deficiency accelerates UVB-induced HaCaT cell senescence by regulating ferroptosis.","authors":"Yan Teng, Junjia He, Yeyu Shen, Jie Chen, Ye Qian, Youming Huang, Xiaohua Tao, Danfeng Xu, Yibin Fan","doi":"10.1007/s43630-025-00701-2","DOIUrl":"10.1007/s43630-025-00701-2","url":null,"abstract":"<p><p>Prolonged exposure to ultraviolet B (UVB) light leads to the accumulation of reactive oxygen species (ROS), a key contributor to skin aging. Previous studies have demonstrated that UVB exposure results in a deficiency in the expression of TIMP3 in keratinocytes. The objective of this study was to investigate the specific role of TIMP3 in keratinocytes. UVB-treated HaCaT cells were utilized to establish a cellular photoaging model. We found that UVB significantly increased levels of ROS, promoted senescence and ferroptosis, and inhibited the expression of TIMP3 in HaCaT. This inhibition was notably alleviated by Fer-1, a ferroptosis inhibitor. In addition, the knockdown of TIMP3 in HaCaT enhanced senescence by inducing the ferroptosis. Mechanistically, UVB exposure also led to a decrease in the expression of KLF4, a transcription factor that regulated TIMP3 expression. Futhermore, UVB-induced reduced expression of KLF4 and TIMP3 in vivo. Our results suggest that deletion of the KLF4/TIMP3 axis promotes HaCaT cell senescence by facilitating the progression of ferroptosis. TIMP3 may serve as an effective therapeutic target for preventing skin photoaging.</p>","PeriodicalId":98,"journal":{"name":"Photochemical & Photobiological Sciences","volume":" ","pages":"499-509"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143672970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How warming impacts the photosynthetic physiology of the bloom-forming cyanobacterium, Microcystis aeruginosa, under UV exposure.","authors":"Menglin Bao, Yingze Yuan, Shasha Zang, Fang Yan, Zhiguang Xu, Hongyan Wu","doi":"10.1007/s43630-025-00705-y","DOIUrl":"10.1007/s43630-025-00705-y","url":null,"abstract":"<p><p>Microcystis aeruginosa is a common cyanobacterium leading to algal blooms. Coupled effects of temperature increase and UV radiation increase will affect its photosynthesis performance, which may in turn will affect its proliferation and distribution, and change the environmental health of the water body. In this study, M. aeruginosa FACHB 469 was incubated at 25 °C and 30 °C and subjected to photosynthetically active radiation (PAR) and UV radiation (PAR + UVR) to monitor the relevant physiological responses. Exposure to both PAR and PAR + UVR resulted in a decline in PSII maximum quantum yield of M. aeruginosa, with UVR having more significant inhibitory effect. Meanwhile, UVR significantly increased the PSII photoinactivation rate constant (K_pi) and decreased the PSII repair rate constant (K_rec), whereas the warming did not have a significant effect on it, and no significant interaction effect between warming and UVR was observed. Further analysis of the strategies of algal cells to cope with UVR at different temperatures revealed that at 25 °C, algal cells mainly relied on the repair cycle of PSII, and reduced the content of phycocyanin to lower light energy capture, and increased superoxide dismutase (SOD) and catalase (CAT) activities to alleviate the damage of UVR; whereas under warming conditions, algal cells, while relying on PSII repair, mainly photoprotect by strengthening the NPQ mechanism, thus improving their tolerance to UVR. These findings suggest that the differential strategies employed by M. aeruginosa to cope with UVR under varying temperature conditions may influence the resilience of cyanobacterial blooms to environmental stressors in the future.</p>","PeriodicalId":98,"journal":{"name":"Photochemical & Photobiological Sciences","volume":" ","pages":"519-529"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143690483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}