Central Plains Medical Journal最新文献

{"title":"Effects of endoscopic modified total laminoplasty on symptomatic lumbar spinal stenosis","authors":"W. Du, Jue Wang, Yuan Lianjing, W. Qi, Luo Zhixiang","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.05.016","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.05.016","url":null,"abstract":"Objective \u0000To summarize the operation procedure and experience of endoscopic modified total laminoplasty (EMTL), and to investigate its short-term therapeutic effects on symptomatic lumbar spinal stenosis. \u0000 \u0000 \u0000Methods \u0000The clinical data of 22 patients with lumbar spinal stenosis who underwent EMTL in the First Affiliated Hospital of Zhengzhou University from August 2016 to August 2017 were retrospectively analyzed. The age, hospital stay, prior and posterior diameters in sagittal plane, bleeding volume, operation time, incision length, intraoperative and postoperative complications of the two groups were recorded. The effects of operation were evaluated by the visual analogue scale (VAS) of lumbago and lower extremity pain, Oswestry disability index (ODI) and Japan Orthopedic Association (JOA) score before and 1 year after operation. \u0000 \u0000 \u0000Results \u0000Among the 22 patients, 8 males and 14 females were included in the study, mean age (59.3 ± 9.6) years. All patients had neurogenic intermittent claudication with a distance of (339± 130)m. Eight patients showed spondylolisthesis or instability according to preoperative digital radiography (DR), computed tomography (CT) and magnetic resonance imaging (MRI). The VAS, ODI and JOA scores of lumbago and lower extremity pain 1 year after operation were significantly different from those before operation (P<0.05). The mean differences (95% confidence interval) of lumbago VAS, lower extremity VAS, ODI score and JOA score were 5.0 (4.3, 5.6), 4.1 (3.3, 4.8), 38.6 (35.7, 1.5), -14.2 (-16.2, -12.2), respectively, which were significantly improved, compared with those before operation. There was 1 case of dural injury during the operation, and 1 case of replantation without fusion determined by postoperative reexamination. And there was no other complications. \u0000 \u0000 \u0000Conclusions \u0000EMTL is effective in the treatment of symptomatic lumbar spinal stenosis. It can alleviate the symptoms of patients, improve their quality of life and satisfaction, with good safety. \u0000 \u0000 \u0000Key words: \u0000Laminoplasty; Total laminectomy; Minimally invasive; Endoscopy","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"98 1","pages":"53-56"},"PeriodicalIF":0.0,"publicationDate":"2020-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76543342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Curative effects of emergency cervical cerclage on cervical incompetence and related factors influencing prognosis","authors":"Li Peng, Guiping Zhang, Xinyi Dan","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.05.011","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.05.011","url":null,"abstract":"Objective \u0000To investigate the curative effects of emergency cervical cerclage (ECC) on cervical incompetence (CIC), and to analyze the related factors influencing prognosis. \u0000 \u0000 \u0000Methods \u0000The clinical and pathological data from 36 CIC patients treated by ECC in Nanyang First People’s Hospital from June 2016 to June 2018 were retrospectively collected. The curative effects were analyzed. The pregnancy outcomes were compared among patients with different cervical dilatation degrees, and the related factors influencing prognosis were analyzed. \u0000 \u0000 \u0000Results \u0000After ECC, gestational weeks of 36 CIC patients were prolonged by (8.55±4.86)weeks, and the neonatal survival rate was 83.33%(30/36). Compared to cervical dilatation degree>6.0 cm group, cervical dilatation degree≤6.0 cm group had longer prolongation time of gestational week, less abortion cases and better neonatal weight, and the difference between the two groups was significant (P 2.5 cm group had longer prolongation time of gestational week, less abortion cases, better neonatal weight, and the difference between the two groups was significant (P 6.0 cm were independent risk factors influencing pregnancy outcomes (P<0.05). \u0000 \u0000 \u0000Conclusions \u0000The perinatal outcomes are relatively better in CIC patients with cervical dilatation degree ≤6.0 cm and cervical length >2.5 cm. The cervical length ≤2.5 cm and cervical dilatation degree >6.0 cm are independent risk factors of pregnancy outcomes. \u0000 \u0000 \u0000Key words: \u0000Cerclage, cervical; Cervical incompetence; Prognosis; Influencing factor","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"06 1","pages":"37-40"},"PeriodicalIF":0.0,"publicationDate":"2020-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85945992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of triple therapy of chemoradiotherapy, intracavitary brachytherapy and hyperthermia on advanced cervical cancer","authors":"Jia Li, F. Ma","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.05.015","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.05.015","url":null,"abstract":"Objective \u0000To investigate the effects of triple therapy of chemoradiotherapy, intracavitary brachytherapy and hyperthermia in the treatment of advanced cervical cancer. \u0000 \u0000 \u0000Methods \u0000A total of 400 patients with advanced cervical cancer admitted to Shanxi Cancer Hospital from July 2011 to June 2016 were selected as the research subjects. They were divided into study group and control group according to the random number table method. Patients in the control group were treated by conventional chemoradiotherapy and intracavitary brachytherapy, and patients in the study group were treated by hyperthermia on the basis of treatment for control group. The curative effects and the changes of leptin and insulin like growth factor 2 (IGF2) in cervical cancer cells before and after treatment were compared between the two groups. After treatment, patients in the two groups were followed up for 3 years, and the tumor-free survival and death of the two groups were recorded. \u0000 \u0000 \u0000Results \u0000The short-term total effective rate of the study group was 74.00% (148/200), higher than the 53.00% (106/200) of the control group (P 0.05). After treatment, the levels of IGF2 and leptin in the study group were lower than those in the control group (P<0.05). During the 3-year follow-up period, the tumor-free survival rate (62.00%, 124/200) and case fatality rate (5.00%, 10/200) in the study group were significantly lower than the 30.50% (61/200) and 17.00%(34/200) in the control group(P<0.05). \u0000 \u0000 \u0000Conclusions \u0000Triple therapy of chemoradiotherapy, intracavitary brachytherapy and hyperthermia is effective in the treatment of advanced cervical cancer, which is beneficial to the short-term and long-term clinical effect. \u0000 \u0000 \u0000Key words: \u0000Chemoradiotherapy; Advanced cervical cancer; Intraluminal brachytherapy; Hyperthermia","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"9 1","pages":"50-53"},"PeriodicalIF":0.0,"publicationDate":"2020-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87204015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Danzhi Xiaoyao powder on late-onset post-pubertal acne caused by disharmony of Conception and Thoroughfare Vessels","authors":"Xinfen Xu","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.05.029","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.05.029","url":null,"abstract":"Objective \u0000To investigate the clinical effects of Danzhi Xiaoyao powder in the treatment of late-onset post-pubertal acne caused by disharmony of Conception and Thoroughfare Vessels. \u0000 \u0000 \u0000Methods \u0000A retrospective analysis was performed on the clinical data of 72 patients with late-onset post-pubertal acne caused by disharmony of Conception and Thoroughfare Vessels admitted to Heze Hospital of Traditional Chinese Medicine from March 2016 to September 2018. All patients were divided into two groups according to treatment methods, with 36 cases in each group. Patients in the control group were treated with conventional western medicine, and patients in the observation group were treated with Danzhi Xiaoyao powder. The levels of serum sex hormone, improvement of skin rash and clinical therapeutic effect were compared between the two groups. \u0000 \u0000 \u0000Results \u0000Compared with the preoperative indexes, the serum sex hormone levels and global acne grading system (GAGS) scores in the two groups were lower after treatment, and the indexes in observation group were lower than those in the control group, and the difference was statistically significant (P<0.05). The total effective rate of the observation group was 94.44% (34/36), higher than the 72.22% (26/36) of the control group, and the difference was statistically significant (P<0.05). \u0000 \u0000 \u0000Conclusions \u0000Danzhi Xiaoyao powder can effectively reduce the serum sex hormone level and improve the skin rash in the patients with late-onset post-pubertal acne caused by disharmony of Conception and Thoroughfare Vessels. \u0000 \u0000 \u0000Key words: \u0000Delayed acne after puberty caused by disharmony of Conception and Thoroughfare Vessels; Danzhi Xiaoyao powder; Serum sex hormone level; Rash situation","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"82 1","pages":"97-99"},"PeriodicalIF":0.0,"publicationDate":"2020-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79963784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Drug resistance and genotypes of Mycobacterium tuberculosis in Datong area","authors":"C. Wei, Yueping Wang, Shuping Li","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.05.012","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.05.012","url":null,"abstract":"Objective \u0000To analyze the drug resistance and genotypes of Mycobacterium tuberculosis in Datong area. \u0000 \u0000 \u0000Methods \u0000A total of 120 strains of Mycobacterium tuberculosis isolated in the Fourth People’s Hospital of Datong from January 2018 to January 2019 were collected. Drug sensitivity tests were carried out by proportional method. The genotypes of 120 strains of Mycobacterium tuberculosis were analyzed by polymerase chain reaction (PCR) and spacer oligonucleotide typing (spoligotyping). \u0000 \u0000 \u0000Results \u0000Of the 120 strains of Mycobacterium tuberculosis, 78 strains were sensitive to isoniazid, rifampicin, ethambutol and streptomycin, and 42 strains were resistant to these drugs, with the drug resistance rate of 35.00%. Eighty-three strains (69.17%) were Beijing genotype, 37 strains (30.83%) were non-Beijing genotype. Gender, age, affected lung, history of tuberculosis treatment, strain source, genotyping had no significant effect on drug resistance or genotype of tuberculosis strains (P>0.05). \u0000 \u0000 \u0000Conclusions \u0000Beijing genotype Mycobacterium tuberculosis is a major epidemic strain in Datong region, and no significant correlation is found between drug resistance and genotype of Mycobacterium tuberculosis in Datong area. \u0000 \u0000 \u0000Key words: \u0000Mycobacterium tuberculosis; Drug resistance; Genotype; Analysis","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"11 1","pages":"41-43"},"PeriodicalIF":0.0,"publicationDate":"2020-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84558024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of radiofrequency thermocoagulation of lumbar sympathetic ganglion in the treatment of neuropathic pain of lower limbs","authors":"Baohui Zhang","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.04.026","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.04.026","url":null,"abstract":"Objective \u0000To study the clinical effect of radiofrequency thermocoagulation of lumbar sympathetic ganglion in the treatment of neuropathic pain of lower extremity. \u0000 \u0000 \u0000Methods \u0000A total of 44 cases of patients with neuropathic pain of lower extremity treated in Linfen People’s Hospital from January 2017 to February 2019 were selected as research objects.They were divided into observation group and control group based on single random equalization method, with 22 cases in each group. The control group was treated with conventional chemical mutilation, while the observation group was treated with radiofrequency thermocoagulation of lumbar sympathetic nerve. Preoperative and postoperative pain scores, postoperative quality of life scores and preoperative and postoperative skin temperature changes of lower limbs were compared between the two groups. \u0000 \u0000 \u0000Results \u0000There was no significant difference in skin temperature of lower limbs between the two groups before treatment (P>0.05); at 1, 2 and 3 months after treatment, there was a significant difference in skin temperature of lower limbs (P 0.05). VAS pain scores in the observation group were lower than those in the control group at 1, 2 and 3 months after treatment (P<0.05). \u0000 \u0000 \u0000Conclusions \u0000Radiofrequency thermocoagulation of lumbar sympathetic nerve can relieve pain of patients with neuropathic pain of lower extremity, which is safe. \u0000 \u0000 \u0000Key words: \u0000Sympathetic ganglion; Radiofrequency thermocoagulation; Lower limbs; Neuropathic pain","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"70 1","pages":"85-87"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79936257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of efficacy and safety of laparoscopic versus retropubic radical prostatectomy in the treatment of localized prostate cancer","authors":"Jun Fang, Xin Jiang, Zhenpu Wang, Hongli Zhang","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.04.011","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.04.011","url":null,"abstract":"Objective \u0000To compare the efficacy and safety of radical prostatectomy by laparoscopic approach and retropubic approach in patients with localized prostate cancer. \u0000 \u0000 \u0000Methods \u0000Thirty-seven patients with localized prostate cancer treated in Zhengzhou People’s Hospital from January 2013 to June 2018 were divided into two groups according to different surgical approaches. Twenty-two cases in control group were treated by posterior pubic approach, and 15 cases in observation group were treated by laparoscopy. The perioperative indexes such as operation time, indwelling catheter time, hospitalization time, intraoperative bleeding volume and pain score were recorded and compared between the two groups. The incidence of complications such as urinary incontinence, anastomotic stricture, urinary leakage and erectile dysfunction in the two groups were higher than those of the two groups. \u0000 \u0000 \u0000Results \u0000After treatment, the observation group had shorter hospital stay compared with the control group, significantly reduced intraoperative bleeding, lower pain score, but longer operation time (P 0.05). \u0000 \u0000 \u0000Conclusions \u0000In the treatment of radical prostatectomy, laparoscopic approach can achieve the effect similar to that of the retropubic approach, and it has minimally invasive advantage, which is beneficial to the postoperative recovery of the patients. \u0000 \u0000 \u0000Key words: \u0000Prostate cancer; Laparoscopy; Radical resection","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"102 1","pages":"35-37"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89153345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Value of capsule endoscopy in the diagnosis of unexplained gastrointestinal bleeding","authors":"Ji-ye Li","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.04.021","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.04.021","url":null,"abstract":"Objective \u0000To investigute the diagnostic value of capsule endoscopy (CE) for unexplained gastrointestinal bleeding (OGIB). \u0000 \u0000 \u0000Methods \u0000Sixty patients with OGIB in General Hospital of Jinmei Group from January 2014 to February 2018 were divided into group A (n=28) and group B (n=32) according to bleeding stop time. The patients in group A underwent CE examination within 3 day stoping bleeding, while the patients in group B 3 d after stoping bleeding. \u0000 \u0000 \u0000Results \u0000The total positive rate of CE in 60 patients was 90%. The proportion of vascular malformation, multiple ulcers or erosion were higher than other types (P<0.05). The positive detection rate of group A was 100%, the posttive detection of group B rate was 81.25%, the difference was significant (P<0.05); the average hospital stay in group A was shorter than that in group B (P<0.05). \u0000 \u0000 \u0000Conclusions \u0000The positive rate of OGIB diagnosis in CE is higher, and performing examination earlier, can get better diagnosis effect, which can provide guidance for clinical treatment, reduce blood transfusion and shorten hospitalization time. \u0000 \u0000 \u0000Key words: \u0000Gastrointestinal bleeding; Capsule endoscopy; Vascular malformation","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"10 1","pages":"69-71"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89306024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Value of MRI in the diagnosis of shoulder injury","authors":"Guohui Yang, Yuquan Liang, Tao Li, Jinzhao Jiang, Xinping Shen","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.04.002","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.04.002","url":null,"abstract":"Objective \u0000To explore the value of MRI in the diagnosis of shoulder joint injury. \u0000 \u0000 \u0000Methods \u0000Fifteen patients with shoulder joint injury confirmed by shoulder arthroscopy admitted to Shenzhen Hospital of Hong Kong University from January 2015 to December 2018 were selected, the clinical data of preoperative routine MRI and Mr shoulder arthrography (MRA) were analyzed retrospectively. \u0000 \u0000 \u0000Results \u0000Arthroscopic results showed that in 15 patients with shoulder joint injury, there were 2 full-thickness rotator cuff tears, 10 partial rotator cuff tears and 3 glenoid lip injuries. The results of MRA were 2 cases, 10 cases and 3 cases, which were consistent with arthroscopic results. Routine MRI diagnosis results: 1 case of rotator cuff full-thickness tear (correct diagnosis rate was 93.3%, missed diagnosis rate was 50.0%, misdiagnosis rate was 0), 12 cases of rotator cuff partial tear (correct diagnosis rate was 86.7%, missed diagnosis rate was 0, misdiagnosis rate was 40.0%), 2 cases of rotator cuff tear complicated with glenoid lip injury (positive diagnosis rate was 93.3%, missed diagnosis rate 33.3%, misdiagnosis rate was 0), of which 2 cases were misdiagnosed as rotator cuff partial tear MRA and arthroscopy showed 1 case of full-thickness rotator cuff tear and 1 case of glenoid lip injury caused by rotator cuff tear. \u0000 \u0000 \u0000Conclusions \u0000Compared with conventional MRI, MR arthrography can improve the diagnosis accuracy of shoulder joint injury and has clinical application value. \u0000 \u0000 \u0000Key words: \u0000Shoulder arthrography; Magnetic resonance imaging; Glenoid lip; Rotator cuff; Injury","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"52 1","pages":"4-7"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87474085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of efficacy of caffeine citrate versus aminophylline in the treatment of premature infants with apnea","authors":"Jian-ping Zhu","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.04.034","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.04.034","url":null,"abstract":"Objective \u0000To compare the effect of caffeine citrate and aminophylline in the treatment of premature apnea. \u0000 \u0000 \u0000Methods \u0000A total of 230 premature infants with apnea admitted to Linfen People’s Hospital from January 2013 to December 2018 were randomly divided into two groups according to the random number table method, with 115 cases in each group. Caffeine citrate group was treated with caffeine citrate, and aminophylline group was treated with aminophylline. The related clinical indicators, mental development index score (MDI score), psychomotor development index score (PDI score), complications and adverse reactions were compared between the two groups. \u0000 \u0000 \u0000Results \u0000Respiratory support time, total assisted ventilation time, mechanical ventilation time, nasal intermittent positive pressure ventilation (NIPPV) time, nasal continuous positive airway pressure (nCPAP) time, oxygen therapy time, medication time, hospitalization time and hospitalization cost in the citrate caffeine group were significantly lower than those in the aminophylline group. The corrected MDI scores and PDI scores at 6 months and 12 months were significantly higher than those in the aminophylline group; the incidence of bronchopulmonary dysplasia (BPD), patent ductus arteriosus (PDA) and brain injury was significantly lower than those of the aminophylline group; feeding intolerance, and the incidence of polyuria and hypokalemia were significantly lower than those of the aminophylline group, and the difference were statistically significant (P<0.05). \u0000 \u0000 \u0000Conclusions \u0000Compared with aminophylline, caffeine citrate has more stable effect and higher safety on premature apnea. \u0000 \u0000 \u0000Key words: \u0000Caffeine citrate; Aminophylline; Premature infant; Apnea","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"3 1","pages":"110-113"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86447524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}