Case Reports in Women's Health最新文献_第3页

Early-onset intrahepatic cholestasis of pregnancy resulting from a genetic mutation: A case report 由基因突变引起的妊娠早期肝内胆汁淤积：1例报告

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Case Reports in Women's Health Pub Date : 2025-05-13 DOI: 10.1016/j.crwh.2025.e00714

Alyssa Gonzalez , Courtney Fant , Ashten Waks , Thao Le , Jonathan G. Steller

{"title":"Early-onset intrahepatic cholestasis of pregnancy resulting from a genetic mutation: A case report","authors":"Alyssa Gonzalez , Courtney Fant , Ashten Waks , Thao Le , Jonathan G. Steller","doi":"10.1016/j.crwh.2025.e00714","DOIUrl":"10.1016/j.crwh.2025.e00714","url":null,"abstract":"<div><div>Intrahepatic cholestasis of pregnancy (ICP) is a pregnancy-specific condition characterized by pruritus and elevated bile acids. It typically manifests in the third trimester of pregnancy and has been associated with hormonal and genetic factors. Early-onset ICP poses unique diagnostic challenges and may contribute to increased risks of adverse maternal and fetal outcomes. We present a case of severe ICP identified in the early second trimester and later attributed to a rare gene variant.</div><div>A 24-year-old patient (G3P0202) was admitted at 17 weeks of gestation with pruritis, abdominal pain, and jaundice. Laboratory studies were notable for elevated total and direct bilirubin as well as elevated bile acids. The patient's medical history included early-onset ICP accompanied by jaundice in all previous pregnancies. A cholestasis gene panel revealed an autosomal recessive variant in the ABCB11 gene, which encodes a bile salt export pump and is associated with benign recurrent intrahepatic cholestasis (BRIC). Throughout the duration of her pregnancy, the patient was co-managed with the hepatobiliary service, and her symptoms were adequately controlled with ursodeoxycholic acid, rifampin, and hydroxyzine. She labored spontaneously at 34 weeks of gestation and delivered a healthy infant.</div><div>This case underscores the importance of genetic evaluation in the assessment of atypical ICP, particularly in early-onset, recurrent, or treatment-refractory cases. It also highlights the need for multidisciplinary management of complex cases with obstetricians, hepatologists, and genetic counselors.</div></div>","PeriodicalId":9657,"journal":{"name":"Case Reports in Women's Health","volume":"46 ","pages":"Article e00714"},"PeriodicalIF":0.7,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144069458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Spontaneous second-trimester uterine rupture in an unscarred uterus: A case report and review of literature 无瘢痕子宫妊娠中期自发性子宫破裂一例报告及文献复习

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Case Reports in Women's Health Pub Date : 2025-04-29 DOI: 10.1016/j.crwh.2025.e00711

Everett Lwamulungi, Corrine Arara, Jeevan Marasinghe, Jacqueline Van Dam

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Successful conservative management of myiasis of an episiotomy wound and the uterine cavity postnatally: A case report 成功保守治疗会阴切开伤口及产后子宫腔粘连1例

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Case Reports in Women's Health Pub Date : 2025-04-18 DOI: 10.1016/j.crwh.2025.e00709

Satyala Satya Priya , Singuang Kamei Gaithaoliu , Kim Johanna Catharina Verschueren , Parishuddharao Koduri

{"title":"Successful conservative management of myiasis of an episiotomy wound and the uterine cavity postnatally: A case report","authors":"Satyala Satya Priya , Singuang Kamei Gaithaoliu , Kim Johanna Catharina Verschueren , Parishuddharao Koduri","doi":"10.1016/j.crwh.2025.e00709","DOIUrl":"10.1016/j.crwh.2025.e00709","url":null,"abstract":"<div><div>Myiasis refers to an infestation by maggots or fly larvae. Urogenital myiasis, particularly in the uterine cavity, is extremely rare. Previously reported cases involved uterine prolapses, typically managed with hysterectomy. We describe the successful conservative management of myiasis in an episiotomy wound with extension into the uterine cavity. The case involved a woman in her 30s who gave birth to her third child eight days prior and presented with a painful and infected episiotomy site with “worms” emerging from her vagina. Her poverty had led to her malnourishment and poor hygiene; she was being treated for pulmonary tuberculosis. She required 11 days of inpatient care, which included broad-spectrum antibiotics, a three- to five-day course of ivermectin, clindamycin and albendazole, larvae extraction, manual vacuum aspiration, uterine cavity irrigation and the daily application of a menstrual pad soaked in turpentine oil. No further maggots were detected near the end of her hospital stay, nor at follow-up. This case demonstrates that conservative treatment can be effective, though it requires patience. Ensuring proper nutritional status and personal hygiene in the postpartum period is critical to preventing wound infections complicated by myiasis.</div></div>","PeriodicalId":9657,"journal":{"name":"Case Reports in Women's Health","volume":"46 ","pages":"Article e00709"},"PeriodicalIF":0.7,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143854529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Russell body cervicitis: A case report and literature review highlighting diagnostic pitfalls 罗素体宫颈炎：一例报告和文献回顾突出诊断缺陷

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Case Reports in Women's Health Pub Date : 2025-04-15 DOI: 10.1016/j.crwh.2025.e00707

Lalani De Silva , Kaumadi Udeshika , Sinha De Silva , Priyani Amarathunga

{"title":"Russell body cervicitis: A case report and literature review highlighting diagnostic pitfalls","authors":"Lalani De Silva , Kaumadi Udeshika , Sinha De Silva , Priyani Amarathunga","doi":"10.1016/j.crwh.2025.e00707","DOIUrl":"10.1016/j.crwh.2025.e00707","url":null,"abstract":"<div><div>Russell bodies have been observed in various inflammatory and neoplastic conditions, although their presence in the female genital tract is rare, with fewer than ten documented cases of Russell body cervicitis. This case report appears to be the first of Russell body cervicitis identified during pregnancy. A 28-year-old woman, at 20 weeks of gestation, underwent a cervical polypectomy after a polyp was detected incidentally during a cervical cerclage procedure. Pathological examination revealed an inflamed endocervical polyp with predominant plasma cell infiltrate. Most of the plasma cells contained intracytoplasmic Russell bodies and there were some Mott cells. Immunohistochemical stains confirmed the polyclonal nature of the plasma cell infiltrate.</div><div>This report highlights the diagnostic challenges associated with Russell body cervicitis, given its rarity and histological resemblance to other inflammatory and neoplastic conditions. A review of the literature reveals that the few reported cases presented as a non-neoplastic process during reproductive age, with an uneventful follow-up. This report contributes to the limited knowledge of Russell body cervicitis, particularly in the context of pregnancy.</div></div>","PeriodicalId":9657,"journal":{"name":"Case Reports in Women's Health","volume":"46 ","pages":"Article e00707"},"PeriodicalIF":0.7,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143843107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hemangioma of the umbilical cord: A case report and proposal for standardised reporting criteria 脐带血管瘤：一例报告及标准化报告标准的建议

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Case Reports in Women's Health Pub Date : 2025-04-05 DOI: 10.1016/j.crwh.2025.e00708

Isabella Charlotte Maréchal-Ross , Sashi Siva , Karen Mizia , Jeremy Nicholas Pulvers , Isabella Turton , Ali Moghimi

{"title":"Hemangioma of the umbilical cord: A case report and proposal for standardised reporting criteria","authors":"Isabella Charlotte Maréchal-Ross , Sashi Siva , Karen Mizia , Jeremy Nicholas Pulvers , Isabella Turton , Ali Moghimi","doi":"10.1016/j.crwh.2025.e00708","DOIUrl":"10.1016/j.crwh.2025.e00708","url":null,"abstract":"<div><div>Umbilical cord hemangiomas are rare benign vascular anomalies with limited documentation in the literature. Given their association with adverse perinatal outcomes, standardised criteria for reporting and monitoring are needed. This case report presents an instance of umbilical cord hemangioma and proposes a structured framework for future documentation.</div><div>A comprehensive literature review using OVID Medline and Embase identified cases of umbilical cord hemangiomas, their clinical presentations, and maternal and neonatal outcomes. A case diagnosed in the third trimester is presented, detailing antenatal surveillance, histopathological findings, and perinatal outcomes. Key parameters were analysed in the context of the literature to inform standardised reporting criteria.</div><div>A 36-year-old woman (G3P2) was diagnosed with an umbilical cord hemangioma at 29 + 3 weeks gestation following a routine growth scan. Serial ultrasound scans demonstrated lesion stability until 35 + 4 weeks, prompting increased fetal surveillance. Multidisciplinary consensus favoured expectant management, leading to an uncomplicated spontaneous vaginal delivery at 39 weeks. Histopathology confirmed a cord hemangioma composed of dilated, ectatic vascular channels lined by endothelial cells.</div><div>This case contributes to the growing body of evidence on umbilical cord hemangiomas by providing detailed clinical, ultrasound, and histopathological findings. Successful expectant management and favourable perinatal outcomes highlight the role of serial ultrasound surveillance. Given the rarity and potential risks of these lesions, standardised reporting is essential to improve understanding and to guide management. By proposing a set of standardised reporting criteria, this case report serves as a step toward enhancing data consistency and informing management strategies.</div></div>","PeriodicalId":9657,"journal":{"name":"Case Reports in Women's Health","volume":"46 ","pages":"Article e00708"},"PeriodicalIF":0.7,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143791010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Infliximab treatment for Cronkhite-Canada syndrome in pregnancy: A case report 英夫利昔单抗治疗妊娠期克朗凯特-加拿大综合征1例报告

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Case Reports in Women's Health Pub Date : 2025-03-30 DOI: 10.1016/j.crwh.2025.e00706

Ayano Rosemary Nakamura , Shuji Yamamoto , Yoshitsugu Chigusa , Masaki Mandai , Haruta Mogami

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Uterine rupture in labor after prior ultrasound-guided percutaneous microwave ablation of uterine fibroids: A case report 超声引导下经皮微波子宫肌瘤消融后分娩子宫破裂1例

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Case Reports in Women's Health Pub Date : 2025-03-14 DOI: 10.1016/j.crwh.2025.e00702

Yucui Zeng, Yanlan Wang, Xiaoyan Guang

{"title":"Uterine rupture in labor after prior ultrasound-guided percutaneous microwave ablation of uterine fibroids: A case report","authors":"Yucui Zeng, Yanlan Wang, Xiaoyan Guang","doi":"10.1016/j.crwh.2025.e00702","DOIUrl":"10.1016/j.crwh.2025.e00702","url":null,"abstract":"<div><div>Ultrasound-guided percutaneous microwave ablation for the treatment of uterine fibroids has gained widespread clinical application due to its efficacy. However, reports on fertility outcomes and pregnancy complications following this treatment remain scarce. This report presents the case of a 31-year-old woman who underwent ultrasound-guided percutaneous microwave ablation for uterine fibroids. Regular postoperative follow-up revealed a significant reduction in the size of the uterine fibroids. Six months later, the patient successfully achieved natural conception, and her pregnancy progressed without any abnormalities. Given her strong preference for vaginal delivery, she was admitted to hospital at 40 weeks of gestation for monitoring when she began to exhibit signs of labor. However, uterine rupture occurred without any apparent warning during the labor. Following emergency surgical intervention, the neonate and the patient had a favorable outcome. This case underscores the efficacy of percutaneous microwave ablation for uterine fibroids but also emphasizes the need for postoperative follow-up to promptly identify any complications during the third trimester of pregnancy.</div></div>","PeriodicalId":9657,"journal":{"name":"Case Reports in Women's Health","volume":"46 ","pages":"Article e00702"},"PeriodicalIF":0.7,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143688018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Marginal resection preferred over radical resection for a large abdominal wall desmoid tumor during pregnancy: A case report 妊娠期腹壁大硬纤维瘤边缘切除优于根治性切除1例

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Case Reports in Women's Health Pub Date : 2025-03-13 DOI: 10.1016/j.crwh.2025.e00701

Riku Watanabe , Hiroki Shinmura , Yasuyuki Yokoyama , Takashi Matsushima

{"title":"Marginal resection preferred over radical resection for a large abdominal wall desmoid tumor during pregnancy: A case report","authors":"Riku Watanabe , Hiroki Shinmura , Yasuyuki Yokoyama , Takashi Matsushima","doi":"10.1016/j.crwh.2025.e00701","DOIUrl":"10.1016/j.crwh.2025.e00701","url":null,"abstract":"<div><div>Desmoid tumors are locally aggressive soft-tissue tumors known for their lack of metastatic potential but high recurrence rate after resection. Few cases of desmoid tumors during pregnancy have been reported, making treatment decisions more challenging.</div><div>This report presents the case of a woman with an abdominal wall desmoid tumor resected at 17 weeks of gestation. The large mass (13.4 cm × 7.4 cm) was compressing the uterus, which necessitated surgical intervention. Marginal resection of the tumor was performed with microscopically positive margins. The patient's postoperative course was uneventful, and she had a normal vaginal delivery at 38 weeks. No recurrence of the tumor was observed at 24-month follow-up. This case represents the largest pregnancy-related abdominal desmoid tumor (22 cm × 12 cm) resected marginally during pregnancy. The procedure allowed for a vaginal delivery rather than a cesarean section.</div><div>Surgical management of desmoid tumors in pregnancy should aim to remove the tumor while preserving function and anatomical integrity. While this approach is feasible for smaller tumors, larger tumors, as in this case, may result in loss of function and anatomical structure. This raises the question of whether marginal resection should be considered when preservation of function and structure is not feasible with radical resection. This case reinforces the fundamental surgical principle that when clear surgical margins cannot be achieved without compromising function and structure, marginal resection should be considered.</div></div>","PeriodicalId":9657,"journal":{"name":"Case Reports in Women's Health","volume":"46 ","pages":"Article e00701"},"PeriodicalIF":0.7,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143683209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Glanzmann's thrombasthenia in a twin pregnancy: A case report 双胎妊娠的Glanzmann血栓缺乏症1例

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Case Reports in Women's Health Pub Date : 2025-03-07 DOI: 10.1016/j.crwh.2025.e00697

Vicky X. Xu , Shaun P. Brennecke

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Vaginocutaneous fistula caused by recurrent labial abscess: A case report 复发性唇脓肿致阴道皮肤瘘1例

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Case Reports in Women's Health Pub Date : 2025-03-06 DOI: 10.1016/j.crwh.2025.e00698

Komkrit Aimjirakul, Teerapan Seehanantawong, Apisith Saraluck

引用次数: 0