Case Reports in Women's Health最新文献

Desmoid tumor in pregnancy complicated by deep vein thrombosis: A case report 妊娠硬纤维瘤合并深静脉血栓1例

IF 0.6

Case Reports in Women's Health Pub Date : 2025-09-30 DOI: 10.1016/j.crwh.2025.e00754

Monchai Suntipap , Potsanop Kassayanan , Kasidis Nontaprom

{"title":"Desmoid tumor in pregnancy complicated by deep vein thrombosis: A case report","authors":"Monchai Suntipap , Potsanop Kassayanan , Kasidis Nontaprom","doi":"10.1016/j.crwh.2025.e00754","DOIUrl":"10.1016/j.crwh.2025.e00754","url":null,"abstract":"<div><div>Desmoid tumor is a rare, locally aggressive soft-tissue neoplasm that primarily arises from the abdominal wall. Deep vein thrombosis is more common in pregnancy due to hypercoagulability. The coexistence of desmoid tumor and pregnancy complicated by deep vein thrombosis is extremely rare and poses unique diagnostic and therapeutic challenges.</div><div>A 29-year-old woman, gravida 2 para 1, with obesity, presented at 28 + 6 weeks of gestation for routine antenatal care. She had a history of left lower limb deep vein thrombosis and presented with progressive leg swelling. Ultrasonography revealed a 10.7 × 6.5 × 10.6 cm abdominal wall mass arising from the left rectus abdominis compressing the left external iliac vein consistent with chronic deep vein thrombosis. Because of financial constraints, warfarin was prescribed temporarily instead of low-molecular-weight heparin. At 38 + 5 weeks of gestation, elective cesarean delivery was performed with a modified surgical approach to avoid damage to the tumor. Resection was deferred due to the high risk of hemorrhage while on anticoagulation. A healthy female newborn was delivered. Postpartum biopsy confirmed desmoid-type fibromatosis with extension into adjacent muscles and iliac vessels. Radiotherapy was planned but delayed, again owing to financial constraints. Lifelong anticoagulation with warfarin and surveillance were planned for the patient.</div><div>The case highlights the importance of considering abdominal wall tumors as a potential cause of pregnancy-related deep vein thrombosis. It also demonstrates how financial considerations can shape clinical decisions and underscores the role of multidisciplinary planning in optimizing maternal and fetal outcomes.</div></div>","PeriodicalId":9657,"journal":{"name":"Case Reports in Women's Health","volume":"48 ","pages":"Article e00754"},"PeriodicalIF":0.6,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145218856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Interstitial pregnancy after frozen embryo transfer in a woman with prior bilateral salpingectomy: A case report and literature review 双侧输卵管切除术后冷冻胚胎移植后间质性妊娠一例报告及文献复习

IF 0.6

Case Reports in Women's Health Pub Date : 2025-09-21 DOI: 10.1016/j.crwh.2025.e00753

Caterina Iaquinta, Ginevra Guarrera, Caterina De Luca, Carmela Votino, Alessandro Svelato, Fulvio Zullo, Roberta Venturella

{"title":"Interstitial pregnancy after frozen embryo transfer in a woman with prior bilateral salpingectomy: A case report and literature review","authors":"Caterina Iaquinta, Ginevra Guarrera, Caterina De Luca, Carmela Votino, Alessandro Svelato, Fulvio Zullo, Roberta Venturella","doi":"10.1016/j.crwh.2025.e00753","DOIUrl":"10.1016/j.crwh.2025.e00753","url":null,"abstract":"<div><div>We describe a rare case of interstitial pregnancy following frozen embryo transfer in a woman with previous bilateral salpingectomy. The 33-year-old patient with a history of recurrent early pregnancy loss conceived after in vitro fertilization. Transvaginal ultrasound revealed a gestational sac with cardiac activity implanted in the interstitial portion of the left uterine cornua, surrounded by a thin myometrial mantle. Medical management with methotrexate was unsuccessful, and serum human chorionic gonadotropin levels continued to rise. The patient underwent laparoscopic cornual wedge resection using local infiltration, monopolar resection, and double-layer closure. The procedure was completed with minimal blood loss, an uneventful postoperative course, and preservation of uterine integrity and future fertility potential. The patient was discharged on the second postoperative day, and follow-up confirmed a steady decline in human chorionic gonadotropin levels. This case highlights that interstitial pregnancy may occur even after bilateral salpingectomy, underlining the importance of early ultrasound surveillance, timely surgical management, and preventive strategies such as complete cornual excision at salpingectomy and single embryo transfer to reduce risks and optimize reproductive outcomes.</div></div>","PeriodicalId":9657,"journal":{"name":"Case Reports in Women's Health","volume":"48 ","pages":"Article e00753"},"PeriodicalIF":0.6,"publicationDate":"2025-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145156805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Discordant phenotypic outcomes in monozygotic twins conceived via IVF: A case report involving Hirschsprung's disease, tricuspid and pulmonary atresia, and orofacial clefts without detectable genetic mutation 通过体外受精怀孕的同卵双胞胎的不一致表型结果：一例报告涉及先天性巨尖症候群病，三尖瓣和肺闭锁，以及没有可检测到的基因突变的口面部裂

IF 0.6

Case Reports in Women's Health Pub Date : 2025-09-20 DOI: 10.1016/j.crwh.2025.e00752

Sonia Gayete-Lafuente , Umar Mian , Elizabeth Choong , David H. Barad , Norbert Gleicher

引用次数: 0

Female genital tuberculosis in an infertility patient resulting in destruction of ovarian tissue: A case report 不孕患者的女性生殖器结核导致卵巢组织破坏：一例报告

IF 0.6

Case Reports in Women's Health Pub Date : 2025-09-15 DOI: 10.1016/j.crwh.2025.e00749

Rachel Watkin , Kalen Hubbs , Michael Clark , Shannon Wood

{"title":"Female genital tuberculosis in an infertility patient resulting in destruction of ovarian tissue: A case report","authors":"Rachel Watkin , Kalen Hubbs , Michael Clark , Shannon Wood","doi":"10.1016/j.crwh.2025.e00749","DOIUrl":"10.1016/j.crwh.2025.e00749","url":null,"abstract":"<div><div>Female genital tuberculosis is an important cause of infertility in endemic regions; it most often affects the fallopian tubes and uterine endometrium, though involvement of the ovaries, cervix, and vagina/vulva have also been reported.</div><div>This report concerns the case of a 30-year-old nulligravid woman who presented for evaluation following discovery of a right adnexal mass in the setting of right-sided abdominal pain. On initial evaluation, the patient also reported a history of secondary amenorrhea and the inability to conceive for six months. Laparoscopic and hysteroscopic findings were concerning for extensive adhesive disease resulting in loss of normal fallopian tube and uterine architecture, as well as complete obliteration of the right ovary. Ultimately, the patient's history and surgical findings were highly suggestive of female genital tuberculosis with sequelae resulting in diffuse pelvic organ disease. An endometrial biopsy confirmed the diagnosis with a positive tuberculosis PCR and acid-fast bacillus culture.</div><div>This case highlights the importance in considering female genital tuberculosis in the workup of infertility, the obstacles to definitive diagnosis, and the detrimental impact longstanding disease can have on pelvic organ function. Additionally, the loss of normal ovarian tissue in this patient may provide a pathophysiologic basis for the previously established association between diminished ovarian reserve and female genital tuberculosis.</div></div>","PeriodicalId":9657,"journal":{"name":"Case Reports in Women's Health","volume":"48 ","pages":"Article e00749"},"PeriodicalIF":0.6,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145120502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acute non-puerperal uterine inversion caused by a giant uterine leiomyoma with angioleiomyomatous features: A case report 具有血管平滑肌瘤特征的巨大子宫平滑肌瘤致急性非产褥期子宫内翻1例

IF 0.6

Case Reports in Women's Health Pub Date : 2025-09-02 DOI: 10.1016/j.crwh.2025.e00747

Volkan Karatasli , Neslihan Bayramoglu , Ferhat Coskun

{"title":"Acute non-puerperal uterine inversion caused by a giant uterine leiomyoma with angioleiomyomatous features: A case report","authors":"Volkan Karatasli , Neslihan Bayramoglu , Ferhat Coskun","doi":"10.1016/j.crwh.2025.e00747","DOIUrl":"10.1016/j.crwh.2025.e00747","url":null,"abstract":"<div><div>Non-puerperal uterine inversion is an extremely rare condition most often associated with uterine tumors. A 48-year-old woman presented with sudden vaginal bleeding and a large protruding mass. Emergency surgery revealed complete uterine inversion caused by a giant pedunculated mass arising from the uterine fundus. The tumor was excised vaginally, and the uterus was manually repositioned. Because multiple fibroids were also present and fertility was not desired, a total abdominal hysterectomy with bilateral salpingo-oophorectomy was performed. Histopathological examination revealed a leiomyoma with prominent angioleiomyomatous features, characterized by spindle cells surrounding thick-walled vascular structures and immunopositivity for desmin, smooth muscle actin, and progesterone receptor. The postoperative course was uneventful, and no recurrence was observed during 60 months of follow-up. This case highlights a rare morphological variant of uterine leiomyoma presenting with acute non-puerperal inversion and emphasizes the importance of early recognition and prompt surgical management.</div></div>","PeriodicalId":9657,"journal":{"name":"Case Reports in Women's Health","volume":"47 ","pages":"Article e00747"},"PeriodicalIF":0.6,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144988073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multidisciplinary team management of caesarean scar ectopic pregnancy progressing to a live birth and caesarean hysterectomy at 34 weeks: A case report 多学科团队对剖宫产瘢痕异位妊娠进展到活产和34周剖宫产子宫切除术的处理：1例报告

IF 0.6

Case Reports in Women's Health Pub Date : 2025-08-29 DOI: 10.1016/j.crwh.2025.e00746

Ruihong Xue , Wei Gu , Xiao Lang

{"title":"Multidisciplinary team management of caesarean scar ectopic pregnancy progressing to a live birth and caesarean hysterectomy at 34 weeks: A case report","authors":"Ruihong Xue , Wei Gu , Xiao Lang","doi":"10.1016/j.crwh.2025.e00746","DOIUrl":"10.1016/j.crwh.2025.e00746","url":null,"abstract":"<div><div>Progression of a caesarean scar ectopic pregnancy (CSEP) to a live birth is exceptionally rare. Whether the placenta should be removed during a caesarean section for patients with a CSEP complicated by severe placenta accreta spectrum remains unclear. This report presents the case of a 42-year-old multigravida with two prior caesarean sections who presented with CSEP at 6 weeks. Despite recommendations for termination, the patient decided to continue the pregnancy. Serial imaging confirmed a progressive placenta accreta spectrum. At 34+ weeks of gestation, a caesarean hysterectomy was successfully performed under the management of a multidisciplinary team, with good maternal and infant outcomes. The management of a CSEP progressing to a live birth during the third trimester requires provider expertise and multidisciplinary treatment and should be individualized. In the present case, caesarean hysterectomy was performed without attempting placental removal, which might have significantly decreased blood loss. While the patient survived, the management remains controversial, and women with CSEP opting for expectant management should be informed about the lack of conclusive evidence on its safety and associated risks. Such options can be considered only in a highly equipped specialist centre with access to a multidisciplinary team.</div></div>","PeriodicalId":9657,"journal":{"name":"Case Reports in Women's Health","volume":"47 ","pages":"Article e00746"},"PeriodicalIF":0.6,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144916713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Laparoscopic management of a heterotopic cornual pregnancy following first-trimester miscarriage – A case report and literature review 早期妊娠流产后异位角妊娠的腹腔镜治疗- 1例报告及文献复习

IF 0.6

Case Reports in Women's Health Pub Date : 2025-08-22 DOI: 10.1016/j.crwh.2025.e00745

Vishal Bahall , Reiaz Mohammed , Lance De Barry

{"title":"Laparoscopic management of a heterotopic cornual pregnancy following first-trimester miscarriage – A case report and literature review","authors":"Vishal Bahall , Reiaz Mohammed , Lance De Barry","doi":"10.1016/j.crwh.2025.e00745","DOIUrl":"10.1016/j.crwh.2025.e00745","url":null,"abstract":"<div><div>Heterotopic pregnancies, defined by the simultaneous occurrence of an intrauterine and ectopic pregnancy, present a rare but potentially life-threatening diagnostic and surgical challenge. Heterotopic pregnancy is rare in spontaneously conceived pregnancies; however, a dramatic rise in the incidence is observed in patients undergoing assisted reproductive technology procedures. Moreover, cornual localization comprises only a minority of ectopic cases yet bears the highest maternal mortality rate due to the risk of catastrophic hemorrhage.</div><div>This report presents the case of a 33-year-old woman with a confirmed first-trimester miscarriage who remained asymptomatic but demonstrated persistently elevated β-hCG levels. Transvaginal ultrasonography identified a right cornual ectopic pregnancy. Laparoscopic wedge resection was performed with the preservation of uterine anatomy.</div><div>This case illustrates a critical vulnerability in the follow-up of early pregnancy loss, where residual or ectopic trophoblastic tissue may be misattributed to a slowly resolving miscarriage. It reinforces the value of repeat imaging and surveillance of β-hCG when clinical resolution is incomplete. This report presents one of the first documented cases of asymptomatic, spontaneously conceived heterotopic cornual pregnancy managed laparoscopically in the Caribbean; it contributes to the evolving literature on heterotopic pregnancies in low-risk women and supports early surgical intervention to preserve reproductive potential.</div></div>","PeriodicalId":9657,"journal":{"name":"Case Reports in Women's Health","volume":"47 ","pages":"Article e00745"},"PeriodicalIF":0.6,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144896677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ovarian pregnancy following fresh embryo transfer: A case report and literature review 新鲜胚胎移植后卵巢妊娠：1例报告及文献复习

IF 0.6

Case Reports in Women's Health Pub Date : 2025-08-19 DOI: 10.1016/j.crwh.2025.e00744

Fombeno Kueta Pascal , Johnny El Hanna , Abdelilah Arsalane , Justin Lewis Denakpo

引用次数: 0

Surgical management of complete labial fusion in a postmenopausal woman with application of a fish skin graft: A case report 手术处理完全唇融合在绝经后妇女应用鱼皮移植：1例报告

IF 0.6

Case Reports in Women's Health Pub Date : 2025-08-14 DOI: 10.1016/j.crwh.2025.e00743

Julia Grace Fitzgerald , Nidhi Chawla , Neil John Kocher

引用次数: 0

Incidental detection of a virilizing Sertoli-Leydig cell tumor during cesarean section: A case report 剖宫产术中意外发现男性化的支持- leydig细胞瘤：1例报告

IF 0.6

Case Reports in Women's Health Pub Date : 2025-08-10 DOI: 10.1016/j.crwh.2025.e00742

Roza Mahyoob , Keisuke Sugita , Akiko Yamamoto

{"title":"Incidental detection of a virilizing Sertoli-Leydig cell tumor during cesarean section: A case report","authors":"Roza Mahyoob , Keisuke Sugita , Akiko Yamamoto","doi":"10.1016/j.crwh.2025.e00742","DOIUrl":"10.1016/j.crwh.2025.e00742","url":null,"abstract":"<div><div>Sertoli-Leydig cell tumors are a rare type of sex cord-stromal tumors that are mostly hormonally active (androgenic or estrogenic). Owing to the rarity of this disease, its impact on pregnancy is not fully understood. This report concerns a rare case of a Sertoli-Leydig cell tumor incidentally discovered during a cesarean section. In a resource-poor setting, a 21-year-old woman was referred to hospital for her first childbirth. She had clitoromegaly for a few years, had never had a gynecological consultation, and had not received antenatal care during this pregnancy. Three hours after admission, an emergency cesarean section was indicated because of fetal distress. During the procedure, a right ovarian tumor measuring approximately 10 × 10 cm was found. Considering the patient's age and obstetric history, and the inability to perform histological evaluation during surgery at the hospital she attended, the decision was made to proceed only with tumor resection. Considering the possibility of a sex-cord stromal tumor focusing on the clitoromegaly, histopathological evaluation was performed, and a diagnosis of a Sertoli-Leydig cell tumor was obtained. This case underscores the importance of clinical vigilance for rare hormonally active ovarian tumors during pregnancy, particularly in low-resource settings.</div></div>","PeriodicalId":9657,"journal":{"name":"Case Reports in Women's Health","volume":"47 ","pages":"Article e00742"},"PeriodicalIF":0.6,"publicationDate":"2025-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144828242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0