Case Reports in Women's Health最新文献

{"title":"Bradycardia in the setting of postpartum preeclampsia and influenza A: A case report","authors":"Dalia Rahmon,&nbsp;Kelly Dubay,&nbsp;Sarah Deighton-Collins","doi":"10.1016/j.crwh.2026.e00785","DOIUrl":"10.1016/j.crwh.2026.e00785","url":null,"abstract":"<div><div>Postpartum bradycardia is a rare clinical finding, with limited guidance regarding its evaluation and management. Prior literature suggests that postpartum bradycardia is most commonly associated with preeclampsia, underlying cardiac disease, medication effects, or neuraxial anesthesia. In patients with preeclampsia, management may be particularly challenging, as magnesium sulfate—used for seizure prophylaxis—is theorized to exacerbate bradycardia.</div><div>This report concerns the case of a 33-year-old woman (G3P3003) with an otherwise uncomplicated pregnancy and cesarean delivery who was diagnosed with Influenza A on postpartum day 1 and treated with oseltamivir. She was readmitted on postpartum day 7 with epigastric pain and shortness of breath and was found to have severe sinus bradycardia (heart rate 32–42 beats per minute) and highly elevated blood pressure, consistent with new-onset postpartum preeclampsia with severe features. Cardiac evaluation, including electrocardiography and transthoracic echocardiography, revealed no structural or ischemic abnormalities. The patient was treated with magnesium sulfate for seizure prophylaxis and antihypertensive therapy. Despite persistent bradycardia, she remained hemodynamically stable, and her heart rate gradually normalized over three days without additional intervention. She was discharged in stable condition and remained asymptomatic at follow-up.</div><div>This case highlights postpartum bradycardia as a potential presenting sign of delayed-onset preeclampsia, even following a normotensive pregnancy. Although magnesium sulfate and recent influenza infection were considered as contributing factors, the clinical course supported preeclampsia as the primary etiology. Postpartum bradycardia is often benign and self-limited; however, thorough evaluation is essential to exclude cardiac pathology and guide appropriate management.</div></div>","PeriodicalId":9657,"journal":{"name":"Case Reports in Women's Health","volume":"49 ","pages":"Article e00785"},"PeriodicalIF":0.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146022806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Extreme heat and pregnancy – A growing public health concern","authors":"J.C.G. Neven,&nbsp;C. Quispel","doi":"10.1016/j.crwh.2025.e00762","DOIUrl":"10.1016/j.crwh.2025.e00762","url":null,"abstract":"","PeriodicalId":9657,"journal":{"name":"Case Reports in Women's Health","volume":"49 ","pages":"Article e00762"},"PeriodicalIF":0.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147395683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maternal-fetal complications of non-immune fetal hydrops – mirror syndrome and hypereactio luteinalis with ovarian torsion: A case report","authors":"Helena C. Bartels,&nbsp;Greg Ryan,&nbsp;Edgar Jaeggi,&nbsp;Homero Flores-Mendoza","doi":"10.1016/j.crwh.2025.e00775","DOIUrl":"10.1016/j.crwh.2025.e00775","url":null,"abstract":"<div><div>Mirror syndrome, previously referred to as Ballantyne's syndrome, is a rare obstetric disorder characterized by maternal edema in association with fetal hydrops and placental edema. This report concerns the case of a 35-year-old multiparous woman who developed mirror syndrome secondary to fetal supraventricular tachycardia complicated by hydrops and intrauterine fetal demise. Her pregnancy was further complicated by hypereactio luteinalis with ovarian torsion requiring surgical detorsion. The case highlights the challenges of managing maternal and fetal hydrps, and its rare association with hypereactio luteinalis.</div></div>","PeriodicalId":9657,"journal":{"name":"Case Reports in Women's Health","volume":"49 ","pages":"Article e00775"},"PeriodicalIF":0.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145837247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Single-organ vasculitis of the uterine cervix mimicking cervical cancer: A case report","authors":"Hitomi Kusakabe ,&nbsp;Takuto Fukutome ,&nbsp;Haruka Suzuki ,&nbsp;Yuki Teramoto ,&nbsp;Rin Mizuno ,&nbsp;Taito Miyamoto ,&nbsp;Yukiko Okada ,&nbsp;Masumi Sunada ,&nbsp;Mana Taki ,&nbsp;Koji Yamanoi ,&nbsp;Ryusuke Murakami ,&nbsp;Masaki Mandai","doi":"10.1016/j.crwh.2026.e00787","DOIUrl":"10.1016/j.crwh.2026.e00787","url":null,"abstract":"<div><div>Single-organ vasculitis (SOV) of the uterine cervix is extremely rare and presents significant diagnostic challenges when it mimics malignancy. A 22-year-old woman presented with fever, abdominal pain, and abnormal genital bleeding. Imaging revealed a 5 cm cervical mass with multiple lymphadenopathies, suggesting advanced cervical cancer. Cervical cytology revealed atypical glandular cells with frequent mitotic figures, suggesting cervical adenocarcinoma. The convergence of cytological, clinical, and imaging findings led to a compelling diagnosis of malignancy. However, no malignant findings were observed in the histopathological examination. The vascular media showed complete fibrinoid necrosis and the surrounding area demonstrated dirty necrosis with numerous nuclear fragments, consistent with necrotizing vasculitis. Atypical cells were confined to a very small area. Immunohistochemistry results were negative for p16. Remarkably, the mass regressed spontaneously during follow-up without any intervention. Follow-up cytology revealed persistent atypical features despite clinical resolution, creating a diagnostic dilemma requiring careful clinicopathological correlation. Pathological evaluation and careful observation the avoidance of unnecessary invasive treatments. The final diagnosis was single-organ cervical vasculitis. This appears to be the first reported case of a spontaneously resolving cervical SOV with cytological features indistinguishable from those of an adenocarcinoma. The case highlights the critical limitations of cytological diagnosis in differentiating severe inflammatory changes from malignancies. The experience emphasizes that tissue diagnosis is essential before radical intervention, particularly in young patients in whom fertility preservation is paramount, and demonstrates that cytological findings require careful clinical correlation to prevent unnecessary surgeries.</div></div>","PeriodicalId":9657,"journal":{"name":"Case Reports in Women's Health","volume":"49 ","pages":"Article e00787"},"PeriodicalIF":0.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147302687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Uterine rupture during labor in a patient with endometriosis: A case report","authors":"Julia Häusler ,&nbsp;Claudia Studer ,&nbsp;Kathrin Bütikofer ,&nbsp;Nebojša Stevanović","doi":"10.1016/j.crwh.2026.e00789","DOIUrl":"10.1016/j.crwh.2026.e00789","url":null,"abstract":"<div><div>Uterine rupture is a rare obstetric complication, particularly in women without a prior cesarean delivery. This report describes an intrapartum posterior uterine wall rupture extending into the vagina in a patient with pre-existing endometriosis and presumed adenomyosis, highlighting endometriosis and its surgical management as potential risk factors. A term gravida with a history of two laparoscopic procedures for endometriosis presented with menstrual-like bleeding and contractions. During labor, she developed severe abdominal pain, prompting an emergency cesarean section. Intraoperatively, a 12 cm longitudinal rupture of the posterior uterine wall extending into the pouch of Douglas and the posterior vaginal fornix was identified. The defect was successfully sutured, and hysterectomy was not required. The postpartum outcome for both the mother and the newborn was satisfactory. This case underscores the importance of recognizing endometriosis and its surgical treatment as possible contributing factors to uterine rupture.</div></div>","PeriodicalId":9657,"journal":{"name":"Case Reports in Women's Health","volume":"49 ","pages":"Article e00789"},"PeriodicalIF":0.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146169954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sono-embryonic detection of monochorionic, diamniotic triplets with conjoined twins after in vitro fertilization: A case report and review of the literature","authors":"Ashley B. Zimmermann,&nbsp;Jamie A. Burns,&nbsp;Eran Bornstein","doi":"10.1016/j.crwh.2026.e00780","DOIUrl":"10.1016/j.crwh.2026.e00780","url":null,"abstract":"<div><div>Monochorionic diamniotic triplets with a conjoined pair are exceedingly rare and arise from multiple splitting events of a single zygote. This report presents the earliest documented ultrasound diagnosis of MCDA triplets with a conjoined pair, at 8 weeks and 5 days of gestation, in a patient who underwent in-vitro fertilization with a single embryo transfer. High-resolution transvaginal ultrasound revealed a monochorionic diamniotic configuration with two amniotic sacs: one containing a structurally normal embryo and the other containing di-thoracic parapagus conjoined twins. This case highlights the critical role of ultrasound imaging in the embryonic period to accurately identify complex multifetal pregnancies and to facilitate timely counseling and clinical decision-making. A review of the literature is included to provide context and management considerations for this rare condition.</div></div>","PeriodicalId":9657,"journal":{"name":"Case Reports in Women's Health","volume":"49 ","pages":"Article e00780"},"PeriodicalIF":0.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146022807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Autoimmune syndrome induced by adjuvants (ASIA) following urethral sling placement: A case report","authors":"Muhammed A.M. Hammad ,&nbsp;Gustavo Gryzinski ,&nbsp;Evelyn Minji Pak ,&nbsp;Alexander Bell ,&nbsp;Gamal Ghoniem","doi":"10.1016/j.crwh.2025.e00778","DOIUrl":"10.1016/j.crwh.2025.e00778","url":null,"abstract":"<div><div>A 39-year-old woman developed debilitating systemic symptoms following the placement of a synthetic mid-urethral sling for stress urinary incontinence. Previously in good health, she experienced sepsis and adrenal crisis immediately postoperatively, followed by persistent symptoms including fatigue, postural orthostatic tachycardia syndrome (POTS), neuropathic pain, cognitive dysfunction, autonomic instability, and recurrent infections. Despite extensive multispecialty evaluations, no definitive diagnosis was initially reached. Laboratory testing later revealed positive ANA and mild immune dysregulation. Given her complex autoimmune history, strong family predisposition, and the temporal association with mesh implantation, her presentation was suspected to be consistent with autoimmune syndrome induced by adjuvants (ASIA). She elected to undergo surgical removal of the synthetic sling with placement of an autologous rectus fascia pubovaginal sling. Postoperatively, the patient experienced significant resolution of her symptoms, restored bladder function, and improved quality of life. This case demonstrates a temporal association consistent with ASIA, with complete symptom resolution by 3 months post-explant and sustained well-being at 1 year.</div></div>","PeriodicalId":9657,"journal":{"name":"Case Reports in Women's Health","volume":"49 ","pages":"Article e00778"},"PeriodicalIF":0.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145921303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Congenital factor VII deficiency as a cause of postpartum hemorrhage: A case report","authors":"Janine Russeth Hernández Zanata ,&nbsp;Marco Antonio Gámez Garza ,&nbsp;Ignacio Uriel Macias Paz ,&nbsp;Elias Ledezma Flores ,&nbsp;René Anselmo Del Ángel De León ,&nbsp;José Eugenio Guerra Cárdenas","doi":"10.1016/j.crwh.2026.e00779","DOIUrl":"10.1016/j.crwh.2026.e00779","url":null,"abstract":"<div><div>Obstetric hemorrhage is one of the leading causes of maternal morbidity and mortality worldwide. However, coagulation disorders as an etiology are rare, with a prevalence of less than 1 %. This report concerns the case of a 24-year-old patient with no previous history of bleeding who presented with postpartum hemorrhage at 38.6 weeks of pregnancy after a normal vaginal delivery. The hemorrhage was refractory to the use of uterotonics and compression maneuvers. In the absence of uterine atony, retained products of conception, or obvious trauma, the possibility of an underlying coagulopathy was considered. Initial studies showed an isolated prolongation of prothrombin time, with activated partial thromboplastin time within normal parameters. A correction test with a normal plasma pool was performed, which showed complete correction of prothrombin time. Specific factor quantification confirmed a severe and isolated factor VII deficiency.</div></div>","PeriodicalId":9657,"journal":{"name":"Case Reports in Women's Health","volume":"49 ","pages":"Article e00779"},"PeriodicalIF":0.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145921304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corded and hyalinized endometrioid carcinoma: A case report","authors":"Kathleen Waeldner ,&nbsp;Chinenye Gloria Anaedobe ,&nbsp;Mary I. Whitehead ,&nbsp;Steven Sieber ,&nbsp;Linus Chuang ,&nbsp;Leslie Andriani","doi":"10.1016/j.crwh.2025.e00774","DOIUrl":"10.1016/j.crwh.2025.e00774","url":null,"abstract":"<div><div>Corded and hyalinized endometrioid carcinoma (CHEC) is a rare histologic variant of endometrioid adenocarcinoma first described in 2005. Due to its biphasic appearance, comprising traditional low-grade endometrioid carcinoma and corded/spindled cells within a hyalinized stroma, CHEC may be misdiagnosed as more aggressive malignancies, including uterine carcinosarcoma. Here is presented the case of an 84-year-old woman who was initially diagnosed with uterine carcinosarcoma but was ultimately found to have FIGO Grade 2 Stage IA2 endometrioid adenocarcinoma with CHEC features following multi-institutional pathologic review. Histopathologic and molecular characterization, including wild-type p53 staining, nuclear β-catenin expression, and a CTNNB1 exon 3 mutation, facilitated the amended diagnosis. Given the updated diagnosis, adjuvant treatment was de-escalated to vaginal brachytherapy alone, sparing the patient unnecessary systemic chemotherapy. This case underscores the critical role of molecular and immunohistochemical analysis in differentiating CHEC from more aggressive endometrial cancers, thus preventing overtreatment. Increased awareness and documentation of CHEC are essential to refining diagnostic criteria, informing prognosis, and optimizing patient management. Future studies are needed to further characterize the molecular landscape and clinical behavior of this rare entity.</div></div>","PeriodicalId":9657,"journal":{"name":"Case Reports in Women's Health","volume":"49 ","pages":"Article e00774"},"PeriodicalIF":0.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145973348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unilateral vulvar hematoma after laparoscopic detorsion of the ipsilateral ovary following oocyte retrieval for IVF: A case report and review of anatomy and surgical planning","authors":"Rachel Linfield,&nbsp;Pip Lipkin ,&nbsp;Jenna Reich,&nbsp;Nirali Jain ,&nbsp;Jennifer Blakemore","doi":"10.1016/j.crwh.2026.e00792","DOIUrl":"10.1016/j.crwh.2026.e00792","url":null,"abstract":"<div><div>A case is reported of delayed ovarian torsion following controlled ovarian hyperstimulation and uncomplicated oocyte retrieval, further complicated by post-laparoscopic ipsilateral vulvar hematoma.</div><div>A 37-year-old nulliparous woman with a history of polycystic ovary syndrome presented with clinical symptoms of ovarian torsion on post-retrieval day 8 and underwent laparoscopic detorsion. Her case was complicated by a large non-traumatic vulvar hematoma on post-laparoscopy day 1.</div><div>Despite safe aspiration of follicles at oocyte retrieval and onset of menses on post-operative day 6, her ovaries' prolonged enlargement placed her at risk of delayed ovarian torsion. She had no known underlying risk factors or vascular pathology to explain the etiology of her post-laparoscopy vulvar hematoma. The patient ultimately underwent a successful single euploid embryo transfer, followed by an uncomplicated vaginal delivery of a full-term neonate.</div><div>Ovarian torsion is a rare event amongst patients undergoing in vitro fertilization, with occurrence after the onset of menses even more uncommon. Clinicians should consider close post-retrieval monitoring of patients with high oocyte yield who are at risk of delayed ovarian healing. In addition, vulvar hematoma is a rare complication after laparoscopy, but patients with altered anatomy or in the setting of enlarged ovaries must be given unique consideration.</div></div>","PeriodicalId":9657,"journal":{"name":"Case Reports in Women's Health","volume":"49 ","pages":"Article e00792"},"PeriodicalIF":0.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147354010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}