Case Reports in Women's Health最新文献

Spontaneous broad ligament rupture following uncomplicated vaginal delivery: A case report 无并发症阴道分娩后自发性阔韧带断裂1例

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Case Reports in Women's Health Pub Date : 2025-06-01 DOI: 10.1016/j.crwh.2025.e00718

Martina Beretta, Philippe Demoustier, Gabriel Charaf

引用次数: 0

A case report with pathological insights into cotyledonoid dissecting leiomyoma: Essential for differentiating this rare benign tumor from cancer 子叶鞘夹层平滑肌瘤1例病理分析：鉴别这种罕见良性肿瘤与恶性肿瘤的必要条件

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Case Reports in Women's Health Pub Date : 2025-06-01 DOI: 10.1016/j.crwh.2025.e00719

Masoud Edalati , Karam Khouri , Ahmed Lazim , Shuanzeng Wei , Anjali Seth , Daniela Proca

{"title":"A case report with pathological insights into cotyledonoid dissecting leiomyoma: Essential for differentiating this rare benign tumor from cancer","authors":"Masoud Edalati , Karam Khouri , Ahmed Lazim , Shuanzeng Wei , Anjali Seth , Daniela Proca","doi":"10.1016/j.crwh.2025.e00719","DOIUrl":"10.1016/j.crwh.2025.e00719","url":null,"abstract":"<div><div>Cotyledonoid dissecting leiomyoma (CDL), also known as Sternberg tumor, is a rare uterine leiomyoma variant with distinct imaging, gross, and microscopic features that deviate from classic leiomyomas. Despite its benign nature, CDL frequently mimics malignancy on radiologic and clinical evaluations, posing a diagnostic challenge. Understanding its unique characteristics is crucial for correct diagnosis to prevent unnecessary aggressive treatment. This report concerns the case of a 52-year-old postmenopausal woman with abnormal bleeding and an enlarged uterus. Ultrasound revealed a 4.3 × 3.5 × 3.5 cm complex echogenic mass of undetermined etiology in the right adnexa. MRI demonstrated a heterogeneously enhancing, irregular mass between the right ovary and uterine fundus. Given her postmenopausal status, a total hysterectomy with bilateral salpingo-oophorectomy was performed. Gross examination revealed a red, spongy, nodular, and cystic tumor containing gelatinous material. The mass involved the right lateral uterine wall, extending toward the fundus and round ligament, but remained distinct from the ovary and fallopian tube. Microscopically, interlacing smooth muscle fascicles whorled around prominent thick-walled vessels, confirming the diagnosis of CDL—a rare, benign uterine leiomyoma with a unique gross and microscopic appearance. Recognizing CDL is critical for both clinicians and pathologists to avoid misdiagnosing it as malignancy. Increased awareness can prevent unnecessary radical treatment, ensuring appropriate patient management while avoiding potential overtreatment and associated complications.</div></div>","PeriodicalId":9657,"journal":{"name":"Case Reports in Women's Health","volume":"46 ","pages":"Article e00719"},"PeriodicalIF":0.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144184997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vault dehiscence two years after total abdominal hysterectomy: A case report 腹式全子宫切除术后2年穹窿破裂1例

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Case Reports in Women's Health Pub Date : 2025-06-01 DOI: 10.1016/j.crwh.2025.e00713

Jessica Benton, Honor Mijatovic, Belinda Lowe

{"title":"Vault dehiscence two years after total abdominal hysterectomy: A case report","authors":"Jessica Benton, Honor Mijatovic, Belinda Lowe","doi":"10.1016/j.crwh.2025.e00713","DOIUrl":"10.1016/j.crwh.2025.e00713","url":null,"abstract":"<div><div>Vault dehiscence is a rare but significant complication of hysterectomy that can result in bowel evisceration through the vagina. This condition occurs when there is separation of the surgically created vaginal cuff, which can lead to serious morbidity, including bowel evisceration, ischaemia, and peritonitis. Vault dehiscence usually occurs in the months following a hysterectomy, but there have been a few case reports of late vaginal vault dehiscence. This report explores the case of a 48-year-old multiparous menopausal woman who presented to the emergency department with unprovoked vaginal cuff dehiscence, on a background of open hysterectomy two years prior. The patient had undergone a laparoscopic hiatal hernia repair two weeks prior to her presentation at the emergency department with dehiscence, raising the question of whether that laparoscopic procedure was related to the presentation with vault dehiscence because it had resulted in weakness of the vaginal vault. She underwent emergency laparoscopic surgery to examine the eviscerated bowel and repair the vault defect. This case report outlines the risk factors for vault dehiscence and factors which may be associated with late and unusual presentations of vault dehiscence after hysterectomy.</div></div>","PeriodicalId":9657,"journal":{"name":"Case Reports in Women's Health","volume":"46 ","pages":"Article e00713"},"PeriodicalIF":0.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144178759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fournier's gangrene in a woman with chronic neutropenia presenting at 12 weeks of pregnancy: a case report and literature review 妊娠12周出现慢性中性粒细胞减少症的妇女富尼耶坏疽1例报告及文献复习

IF 0.7

Case Reports in Women's Health Pub Date : 2025-06-01 DOI: 10.1016/j.crwh.2025.e00721

Manuela Neri , Paolo Albino Ferrari , Elisabetta Sanna , Giovanni Caocci , Valerio Vallerino , Sonia Nemolato , Giorgia Locci , Clelia Madeddu , Matteo Runfola , Anna Maria Paoletti , Antonio Macciò

{"title":"Fournier's gangrene in a woman with chronic neutropenia presenting at 12 weeks of pregnancy: a case report and literature review","authors":"Manuela Neri , Paolo Albino Ferrari , Elisabetta Sanna , Giovanni Caocci , Valerio Vallerino , Sonia Nemolato , Giorgia Locci , Clelia Madeddu , Matteo Runfola , Anna Maria Paoletti , Antonio Macciò","doi":"10.1016/j.crwh.2025.e00721","DOIUrl":"10.1016/j.crwh.2025.e00721","url":null,"abstract":"<div><div>The management of Fournier's gangrene in pregnancy in a woman with chronic idiopathic neutropenia is described. A 36-year-old pregnant woman was admitted at 12 weeks of gestation with sepsis, high fever, severe anemia requiring transfusions, and a perianal necrotic area approximately 10 cm in diameter extending to the perineum, consistent with Fournier's gangrene. She required both surgery and medical therapy. Surgery included a laparoscopic defunctioning sigmoid loop colostomy and perineal debridement. The skin and mucous membranes of the perineum were cleansed daily using water irrigation, decontamination and disinfection, and the vagina and rectum were irrigated with antiseptic and antifungal solutions. The necrotic areas were removed. Granulocyte colony-stimulating factor and erythropoietin were administered to restore normal levels of white blood cells and hemoglobin. Vital parameters, hematological values, and clinical examination of the perineum showed progressive improvement during treatment, and complete restoration of the perineum was achieved. The patient successfully carried the pregnancy to term. In conclusion, key factors for success were treatment of the sepsis, loop colostomy, granulocyte growth factor therapy and cleansing of the anus and perineum.</div></div>","PeriodicalId":9657,"journal":{"name":"Case Reports in Women's Health","volume":"46 ","pages":"Article e00721"},"PeriodicalIF":0.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144221684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

First-trimester ultrasound diagnosis of sirenomelia: A case report 妊娠早期超声诊断胎儿畸形1例

IF 0.7

Case Reports in Women's Health Pub Date : 2025-05-27 DOI: 10.1016/j.crwh.2025.e00717

Carla Ettore , Elisa Pappalardo , Ferdinando Antonio Gulino , Giosuè Giordano Incognito , Sebastiano Bianca , Giuseppe Ettore

引用次数: 0

Pyogenic granuloma gravidarum: A case report 化脓性妊娠肉芽肿1例

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Case Reports in Women's Health Pub Date : 2025-05-24 DOI: 10.1016/j.crwh.2025.e00716

Ruth S. Goh , Wee Ming Peh , Christopher Goh Hood Keng

引用次数: 0

Mode of delivery in placental abruption: A case report on difficulty in distinguishing between uterine rupture and placental abruption due to clinical features that overlap 胎盘早剥的分娩方式：由于临床特征重叠，子宫破裂和胎盘早剥难以区分的病例报告

IF 0.7

Case Reports in Women's Health Pub Date : 2025-05-15 DOI: 10.1016/j.crwh.2025.e00715

Stephen Darko , Nnabuike Chibuoke Ngene

{"title":"Mode of delivery in placental abruption: A case report on difficulty in distinguishing between uterine rupture and placental abruption due to clinical features that overlap","authors":"Stephen Darko , Nnabuike Chibuoke Ngene","doi":"10.1016/j.crwh.2025.e00715","DOIUrl":"10.1016/j.crwh.2025.e00715","url":null,"abstract":"<div><div>Amongst the indications for caesarean delivery (CD) in pregnant women presenting with placental abruption (PA), fetal demise near term, and a previous major uterine surgery are peritonitic abdomen and severe vaginal bleeding. When the presence of these two indications is equivocal, deciding on the mode of delivery becomes challenging, as uterine rupture is a differential diagnosis. This case report develops an algorithm for decision-making on the mode of delivery in this context. A 22-year-old woman (G2P1) with a previous CD presented with antepartum hemorrhage (APH) at 36 weeks of gestation. In the previous pregnancy, she developed pre-eclampsia, PA at 34 weeks of gestation, and had CD and stillbirth. In the index pregnancy, she declined aspirin and had no pre-eclampsia. The APH at index presentation was mild-moderate, making the decision on mode of delivery difficult, but CD was favoured due to the possibility of uterine rupture. Another support for this decision was that access to emergency CD might be limited at the busy hospital the patient attended if an attempt at vaginal delivery were employed and an obvious indication for CD developed later. The decision-delivery time was 95 min. Intra-operatively, Couvelaire uterus, retroplacental clot, and left lateral fundal uterine rupture were found. Lower segment CD was performed, and the uterus repaired in layers. In conclusion, individualized care is recommended for women with PA, fetal demise near term, and a previous major uterine surgery. The clinical condition and context are important considerations that should guide the preferred mode of delivery.</div></div>","PeriodicalId":9657,"journal":{"name":"Case Reports in Women's Health","volume":"46 ","pages":"Article e00715"},"PeriodicalIF":0.7,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144071846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Early-onset intrahepatic cholestasis of pregnancy resulting from a genetic mutation: A case report 由基因突变引起的妊娠早期肝内胆汁淤积：1例报告

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Case Reports in Women's Health Pub Date : 2025-05-13 DOI: 10.1016/j.crwh.2025.e00714

Alyssa Gonzalez , Courtney Fant , Ashten Waks , Thao Le , Jonathan G. Steller

{"title":"Early-onset intrahepatic cholestasis of pregnancy resulting from a genetic mutation: A case report","authors":"Alyssa Gonzalez , Courtney Fant , Ashten Waks , Thao Le , Jonathan G. Steller","doi":"10.1016/j.crwh.2025.e00714","DOIUrl":"10.1016/j.crwh.2025.e00714","url":null,"abstract":"<div><div>Intrahepatic cholestasis of pregnancy (ICP) is a pregnancy-specific condition characterized by pruritus and elevated bile acids. It typically manifests in the third trimester of pregnancy and has been associated with hormonal and genetic factors. Early-onset ICP poses unique diagnostic challenges and may contribute to increased risks of adverse maternal and fetal outcomes. We present a case of severe ICP identified in the early second trimester and later attributed to a rare gene variant.</div><div>A 24-year-old patient (G3P0202) was admitted at 17 weeks of gestation with pruritis, abdominal pain, and jaundice. Laboratory studies were notable for elevated total and direct bilirubin as well as elevated bile acids. The patient's medical history included early-onset ICP accompanied by jaundice in all previous pregnancies. A cholestasis gene panel revealed an autosomal recessive variant in the ABCB11 gene, which encodes a bile salt export pump and is associated with benign recurrent intrahepatic cholestasis (BRIC). Throughout the duration of her pregnancy, the patient was co-managed with the hepatobiliary service, and her symptoms were adequately controlled with ursodeoxycholic acid, rifampin, and hydroxyzine. She labored spontaneously at 34 weeks of gestation and delivered a healthy infant.</div><div>This case underscores the importance of genetic evaluation in the assessment of atypical ICP, particularly in early-onset, recurrent, or treatment-refractory cases. It also highlights the need for multidisciplinary management of complex cases with obstetricians, hepatologists, and genetic counselors.</div></div>","PeriodicalId":9657,"journal":{"name":"Case Reports in Women's Health","volume":"46 ","pages":"Article e00714"},"PeriodicalIF":0.7,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144069458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spontaneous second-trimester uterine rupture in an unscarred uterus: A case report and review of literature 无瘢痕子宫妊娠中期自发性子宫破裂一例报告及文献复习

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Case Reports in Women's Health Pub Date : 2025-04-29 DOI: 10.1016/j.crwh.2025.e00711

Everett Lwamulungi, Corrine Arara, Jeevan Marasinghe, Jacqueline Van Dam

引用次数: 0

Successful conservative management of myiasis of an episiotomy wound and the uterine cavity postnatally: A case report 成功保守治疗会阴切开伤口及产后子宫腔粘连1例

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Case Reports in Women's Health Pub Date : 2025-04-18 DOI: 10.1016/j.crwh.2025.e00709

Satyala Satya Priya , Singuang Kamei Gaithaoliu , Kim Johanna Catharina Verschueren , Parishuddharao Koduri

{"title":"Successful conservative management of myiasis of an episiotomy wound and the uterine cavity postnatally: A case report","authors":"Satyala Satya Priya , Singuang Kamei Gaithaoliu , Kim Johanna Catharina Verschueren , Parishuddharao Koduri","doi":"10.1016/j.crwh.2025.e00709","DOIUrl":"10.1016/j.crwh.2025.e00709","url":null,"abstract":"<div><div>Myiasis refers to an infestation by maggots or fly larvae. Urogenital myiasis, particularly in the uterine cavity, is extremely rare. Previously reported cases involved uterine prolapses, typically managed with hysterectomy. We describe the successful conservative management of myiasis in an episiotomy wound with extension into the uterine cavity. The case involved a woman in her 30s who gave birth to her third child eight days prior and presented with a painful and infected episiotomy site with “worms” emerging from her vagina. Her poverty had led to her malnourishment and poor hygiene; she was being treated for pulmonary tuberculosis. She required 11 days of inpatient care, which included broad-spectrum antibiotics, a three- to five-day course of ivermectin, clindamycin and albendazole, larvae extraction, manual vacuum aspiration, uterine cavity irrigation and the daily application of a menstrual pad soaked in turpentine oil. No further maggots were detected near the end of her hospital stay, nor at follow-up. This case demonstrates that conservative treatment can be effective, though it requires patience. Ensuring proper nutritional status and personal hygiene in the postpartum period is critical to preventing wound infections complicated by myiasis.</div></div>","PeriodicalId":9657,"journal":{"name":"Case Reports in Women's Health","volume":"46 ","pages":"Article e00709"},"PeriodicalIF":0.7,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143854529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0