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Clinic of Pediatric Surgery and Traumatology. 儿科外科与创伤科门诊。
Casopis lekaru ceskych Pub Date : 2025-01-01
Radek Štichhauer
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引用次数: 0
Patient blood management - past, present and future. 病人血液管理-过去，现在和未来。
Casopis lekaru ceskych Pub Date : 2025-01-01
Josip Slipac
{"title":"Patient blood management - past, present and future.","authors":"Josip Slipac","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Patient blood management (PBM) is a patient-centered, systematic, evidence-based, multidisciplinary, and multimodal approach to improve patient outcomes by managing and preserving the patient's own blood. The history of PBM dates back to the 19th century, while modern practice has been shaped by programs such as Dr. Denton Cooley's \"bloodless surgery\". Despite advances in transfusion medicine, the safety risks and side effects of transfusion have driven the development of PBM. Today, this program includes optimizing hematopoiesis, reducing blood loss, and improving the tolerance of anemia. PBM improves clinical outcomes and patient safety, and the World Health Organization recommends implementing this program in all countries of the world as a standard of care.</p>","PeriodicalId":9645,"journal":{"name":"Casopis lekaru ceskych","volume":"164 1","pages":"32-34"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144858949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Classification of diabetic foot disease cases using Czech DRG system. 捷克DRG系统在糖尿病足病例分类中的应用。
Casopis lekaru ceskych Pub Date : 2025-01-01
Vladimíra Fejfarová, Pavlína Piťhová, Miroslav Koliba, Alexandra Jirkovská, Jarmila Jirkovská, Hana Kůsová, Miroslav Drienko, Irena Molinari, Miroslav Zvolský
{"title":"Classification of diabetic foot disease cases using Czech DRG system.","authors":"Vladimíra Fejfarová, Pavlína Piťhová, Miroslav Koliba, Alexandra Jirkovská, Jarmila Jirkovská, Hana Kůsová, Miroslav Drienko, Irena Molinari, Miroslav Zvolský","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The implementation of the DRG system into real podiatric practice presupposes the application and adherence to the rules for reporting hospitalizations related to diabetic foot syndrome. The reason is both the cultivation of reimbursements for relatively economically demanding hospitalizations of patients with this late complication and the availability of data providing a national overview of the development and prognosis of patients with diabetic foot syndrome in real-time.</p>","PeriodicalId":9645,"journal":{"name":"Casopis lekaru ceskych","volume":"164 4","pages":"156-160"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146050281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
47th conference of the International Society of Oncology and Biomarkers - ISOBM: A new era of biomarkers in oncology. 第47届国际肿瘤和生物标志物学会会议- ISOBM：肿瘤生物标志物的新时代。
Casopis lekaru ceskych Pub Date : 2025-01-01
Judita Kinkorová, Ondřej Topolčan
{"title":"47th conference of the International Society of Oncology and Biomarkers - ISOBM: A new era of biomarkers in oncology.","authors":"Judita Kinkorová, Ondřej Topolčan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>From October 12-16, 2025, the 47th annual International Society of Oncology and Biomarkers (ISOBM) conference was held in Murnau, Bavaria, under the subtitle \"New Era of Biomarkers in Oncology\". The focus of the conference was the integration of modern technologies in oncology, including biomarker research, molecular diagnostics, and artificial intelligence applications in cancer care. The event welcomed more than 300 participants, 38 exhibitors, and 7 corporate partners from a total of 27 countries. The rich program featured presentations across 17 sessions, panel discussions, 12 workshops, and over 70 posters. The conference thus provided a multidisciplinary platform bringing together laboratory medicine, pathology, molecular biology, clinical oncology, and specialists in data processing and artificial intelligence.</p>","PeriodicalId":9645,"journal":{"name":"Casopis lekaru ceskych","volume":"164 7-8","pages":"361-363"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146092250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Artificial intelligence in biobanking: current situation and future perspectives. 人工智能在生物银行中的应用：现状与未来展望
Casopis lekaru ceskych Pub Date : 2025-01-01
Judita Kinkorová
{"title":"Artificial intelligence in biobanking: current situation and future perspectives.","authors":"Judita Kinkorová","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Biobanks are essential infrastructures for biomedical research and personalized medicine. The exponential growth of heterogeneous data from various sources (genomics, imaging, electronic health records, environmental data) creates opportunities for artificial intelligence (AI) applications to improve data management, biomarker discovery, laboratory automation, and sample accessibility. This article reviews current trends, technical and ethical challenges, GDPR-related considerations, the role of FAIR (findable, accessible, interoperable, reusable) data principles and federated learning, the importance of explainable AI, and implications for the Czech healthcare system. Practical recommendations for safe and sustainable AI integration into biobanks are provided.</p>","PeriodicalId":9645,"journal":{"name":"Casopis lekaru ceskych","volume":"164 7-8","pages":"328-332"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146092263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recommendations for the implementation of European Union regulations on the donation and use of human-derived substances. 关于执行欧洲联盟关于捐赠和使用人类来源物质的条例的建议。
Casopis lekaru ceskych Pub Date : 2025-01-01
Hana Konečná
{"title":"Recommendations for the implementation of European Union regulations on the donation and use of human-derived substances.","authors":"Hana Konečná","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In July 2024, a European Union regulation on substances of human origin came into effect, which is to be implemented into the legislation of member states by August 2027. The fundamental ethical principle remains voluntary and unpaid donation, but the responsibility for addressing related ethical issues is left to the member states. Ethical topics that should be considered during implementation, such as methods of obtaining and compensating donors of substances of human origin, donor anonymity, and the content of informed consents, were addressed in our research project \"Quality and Sustainability of Body Part Donation Programs in the Czech Republic - TA ČR No. TL05000144\", which took place between 2021 and 2023.</p>","PeriodicalId":9645,"journal":{"name":"Casopis lekaru ceskych","volume":"164 4","pages":"166-168"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146050355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Shooting at the Faculty of Arts of Charles University and activation of the trauma plan at the First Surgical Clinic of the General Teaching Hospital. 查尔斯大学文学院枪击事件与综合教学医院第一外科诊所创伤计划的启动。
Casopis lekaru ceskych Pub Date : 2025-01-01
Josef Kraus, Filip Burget
{"title":"Shooting at the Faculty of Arts of Charles University and activation of the trauma plan at the First Surgical Clinic of the General Teaching Hospital.","authors":"Josef Kraus, Filip Burget","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The Trauma Plan is a set of measures to mitigate the consequences of injury in emergencies and crisis situations. It was activated at the First Surgical Clinic of the General University Hospital in December 2023, on the day of the tragic shooting in the building of the Faculty of Arts of Charles University in Prague. Thanks to the practice activations, teams, premises and beds were prepared within 20 minutes without complications. An exceptional case was a gunshot wound that occurred at 350 meters (on the other bank of the Vltava River), the origin of which, however, the patient-foreigner was not aware of and was reported as a fracture of the femur after a fall while fleeing.</p>","PeriodicalId":9645,"journal":{"name":"Casopis lekaru ceskych","volume":"164 3","pages":"90-93"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144858963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Newly discovered documents about J. E. Purkyně at the Anatomical Institute of the 1st Faculty of Medicine, Charles University. 查尔斯大学第一医学院解剖研究所新发现的关于J. E. purkynyi的文件。
Casopis lekaru ceskych Pub Date : 2025-01-01
Markéta Ivánková
{"title":"Newly discovered documents about J. E. Purkyně at the Anatomical Institute of the 1st Faculty of Medicine, Charles University.","authors":"Markéta Ivánková","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":9645,"journal":{"name":"Casopis lekaru ceskych","volume":"164 6","pages":"273-278"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145793353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Late-onset hypogonadism in men over 40 - how to use the updated EAU 2025 guidelines and new findings on the cardiovascular safety of testosterone therapy. 40岁以上男性迟发性性腺功能减退——如何使用更新的EAU 2025指南和睾酮治疗心血管安全性的新发现
Casopis lekaru ceskych Pub Date : 2025-01-01
Marek Broul, Aneta Hujová
{"title":"Late-onset hypogonadism in men over 40 - how to use the updated EAU 2025 guidelines and new findings on the cardiovascular safety of testosterone therapy.","authors":"Marek Broul, Aneta Hujová","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Late-onset hypogonadism is a clinical syndrome defined by androgen-deficiency symptoms and persistently low testosterone; it affects roughly two to eight percent of European men aged 40-79 years and becomes more prevalent with advancing age, obesity and cardiometabolic comorbidities. The 2025 update of the European Association of Urology (EAU) guidelines sets a unified biochemical threshold of total testosterone below 12 nmol/L confirmed by two morning samples and emphasises baseline assessment of luteinizing hormone (LH), follicle-stimulating hormone (FSH), blood pressure and haematocrit before therapy. The large multicentre TRAVERSE trial showed that transdermal testosterone replacement does not increase major adverse cardiovascular events, yet revealed a mild rise in systolic blood pressure, a finding reflected in the latest US Food and Drug Administration (FDA) labelling changes. Building on this evidence, we propose a four-step algorithm encompassing precise diagnosis, judicious initiation of treatment, integrated management of cardiometabolic risk factors and personalised fertility preservation. Such an approach permits effective and safe management of symptomatic late-onset hypogonadism while mitigating long-term risks.</p>","PeriodicalId":9645,"journal":{"name":"Casopis lekaru ceskych","volume":"164 4","pages":"150-155"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146050315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Health literacy in international recommendations and studies. 国际建议和研究中的卫生素养。
Casopis lekaru ceskych Pub Date : 2025-01-01
Alena Šteflová, Jan Dudra
{"title":"Health literacy in international recommendations and studies.","authors":"Alena Šteflová, Jan Dudra","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Health literacy means the ability to acquire, evaluate and apply health-related information. Health literacy affects motivation, health behavior, but also trust in health systems. For the development and improvement of health literacy in the European context, it is necessary to measure health literacy and compare it internationally.</p>","PeriodicalId":9645,"journal":{"name":"Casopis lekaru ceskych","volume":"164 1","pages":"14-16"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144858947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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