Case Reports in Psychiatry最新文献

When Delusion Becomes Reality: A Six-Year Diagnostic Odyssey and Ethical Crisis in a Case of Veridical Spousal Infidelity Belief. 当妄想成为现实：六年的诊断奥德赛和道德危机在一个真实的配偶不忠信念的情况下。

Case Reports in Psychiatry Pub Date : 2026-04-27 eCollection Date: 2026-01-01 DOI: 10.1155/crps/3752206

Alireza Parsapoor, Mehdi Sayyah

{"title":"When Delusion Becomes Reality: A Six-Year Diagnostic Odyssey and Ethical Crisis in a Case of Veridical Spousal Infidelity Belief.","authors":"Alireza Parsapoor, Mehdi Sayyah","doi":"10.1155/crps/3752206","DOIUrl":"https://doi.org/10.1155/crps/3752206","url":null,"abstract":"Background: The diagnosis of delusional disorder, jealousy type, traditionally relies on the criterion of a \"false\" belief. This report describes a complex case in which a belief long considered delusional was ultimately verified, revealing limitations of rigid diagnostic frameworks and raising a profound ethical dilemma.Case presentation: Ms. A, a 42-year-old woman, presented with a fixed, 4-year belief in her husband's infidelity, accompanied by mild depressive symptoms but preserved global functioning. Over a 6-year period, she received treatment from multiple psychiatrists, including sequential trials of antipsychotics (risperidone, olanzapine, and aripiprazole) without benefit. Documented treatment resistance led to a trial of electroconvulsive therapy (ECT). Following the first ECT session, her husband confessed to long-term infidelity and a secret remarriage, while demanding that the clinician withhold this information from the patient.Discussion: This case challenges the diagnostic emphasis on belief falsity and illustrates how prolonged familial deception can sustain misdiagnosis. The protracted, multiprovider treatment history likely contributed to diagnostic entrenchment and therapeutic escalation. Ethically, maintaining secrecy after the confession constituted institutional gaslighting and epistemic injustice, violating core principles of nonmaleficence and autonomy. The clinician's primary duty to the patient must supersede spousal demands for confidentiality in cases of harmful deception.Conclusion: Veridical \"delusions\" require a paradigm shift toward dynamic diagnosis and patient-centered ethics. Clinicians must critically evaluate collateral information, remain alert to epistemic injustice, and prioritize patient welfare and truth disclosure over preservation of harmful familial secrets.","PeriodicalId":9631,"journal":{"name":"Case Reports in Psychiatry","volume":"2026 ","pages":"3752206"},"PeriodicalIF":0.0,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13121555/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147763528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tianeptine Misuse, Dependence, and Clinical Management: Three Case Reports and Literature Review. 天奈肽滥用、依赖与临床处理：3例报告及文献回顾。

Case Reports in Psychiatry Pub Date : 2026-04-20 eCollection Date: 2026-01-01 DOI: 10.1155/crps/2981699

Valeria A Saldana, Paul H Earley, David S Silverstein, Yi-Lang Tang

{"title":"Tianeptine Misuse, Dependence, and Clinical Management: Three Case Reports and Literature Review.","authors":"Valeria A Saldana, Paul H Earley, David S Silverstein, Yi-Lang Tang","doi":"10.1155/crps/2981699","DOIUrl":"https://doi.org/10.1155/crps/2981699","url":null,"abstract":"Tianeptine, an antidepressant approved only in Europe, Asia, and Latin America, is available without regulation in the United States through online vendors and various retail locations. The rise in its misuse has raised public concerns, marked by dramatic dose escalation, rapid tolerance, toxicity, and withdrawal symptoms. Substance use disorder due to another substance (tianeptine) commonly presents with symptoms similar to opioid use disorder. Symptoms of intoxication include euphoria, respiratory depression, and CNS sedation. Withdrawal symptoms may include anxiety, agitation, and gastrointestinal distress. Acute intoxication management may include the use of naloxone and supportive measures. Withdrawal management should consider the use of buprenorphine as a first-line treatment. Clonidine and other medications used for opioid withdrawal may also be beneficial. Cases with chronic use may require intensive interventions, including residential care, long-term follow-up, and close monitoring, as relapse rates are high. This report presents three cases of tianeptine misuse, detailing their presentation, withdrawal symptoms, and treatment, including pharmacological interventions and treatment setting. We further highlight the problems associated with misuse, the unique presentation of the disorder, treatment options for substance use disorder due to another substance (tianeptine), and the urgent need for regulatory oversight.","PeriodicalId":9631,"journal":{"name":"Case Reports in Psychiatry","volume":"2026 ","pages":"2981699"},"PeriodicalIF":0.0,"publicationDate":"2026-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13094364/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147763503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Unusual Case of Multifactorial Catatonia Following Taxane-Based Chemotherapy Regimen. 紫杉烷化疗后多因素紧张症1例。

Case Reports in Psychiatry Pub Date : 2026-04-16 eCollection Date: 2026-01-01 DOI: 10.1155/crps/5820055

Wei Siang Lee, Leslie Lim, Vincent Wong

{"title":"An Unusual Case of Multifactorial Catatonia Following Taxane-Based Chemotherapy Regimen.","authors":"Wei Siang Lee, Leslie Lim, Vincent Wong","doi":"10.1155/crps/5820055","DOIUrl":"10.1155/crps/5820055","url":null,"abstract":"Catatonia is a neuropsychiatric syndrome characterised by motor and behavioural disturbances. While commonly associated with psychiatric conditions, a substantial proportion of cases have medical or drug-induced aetiologies. Chemotherapy can cause catatonia, and taxane-based chemotherapy is known to cause central neurotoxicity; however, taxane-related catatonia has not been reported before. We describe a 75-year-old woman with a schizophrenia in remission, who developed catatonia after docetaxel administration for breast cancer. Her catatonia fulfilled DSM-5-TR criteria and had an initial Bush-Francis catatonia rating scale (BFCRS) score of 23. A lorazepam challenge was positive, and treatment with oral lorazepam resulted in rapid resolution. Mild recurrence during follow-up was successfully managed with lorazepam titration. We discuss the possible link between taxanes, taxane-induced central neurotoxicity (TICN) and catatonia, with neuroscientific, clinical and radiological considerations. This case highlights the potential contribution of taxane chemotherapy to catatonia in a medically complex patient, and underscores the importance of early recognition and prompt treatment of catatonia.","PeriodicalId":9631,"journal":{"name":"Case Reports in Psychiatry","volume":"2026 ","pages":"5820055"},"PeriodicalIF":0.0,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13086532/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147721757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Alice in Wonderland and Ekbom Syndromes in a Bipolar I Manic Episode: A Case Report With Neuroimaging Findings. 爱丽丝梦游仙境和Ekbom综合征在双相I型躁狂发作：一个病例报告与神经影像学发现。

Case Reports in Psychiatry Pub Date : 2026-04-07 eCollection Date: 2026-01-01 DOI: 10.1155/crps/1065938

Yuta Hori, Satoru Yanagaki, Masashi Nibuya, Seishu Nakagawa, Eiji Suzuki

引用次数: 0

Unveiling the Complex Interplay: Sudden Emergence of First-Rank Schneiderian Symptoms Following TMS in a Patient With Severe Depression and Complex Trauma. 揭示复杂的相互作用：严重抑郁症和复杂创伤患者经颅磁刺激后突然出现一级施耐德症状。

Case Reports in Psychiatry Pub Date : 2026-03-05 eCollection Date: 2026-01-01 DOI: 10.1155/crps/5528976

Jaskaran Singh, Luba Leontieva, S D Sperry, Karan Sachdeva, Sanobar Jaka

{"title":"Unveiling the Complex Interplay: Sudden Emergence of First-Rank Schneiderian Symptoms Following TMS in a Patient With Severe Depression and Complex Trauma.","authors":"Jaskaran Singh, Luba Leontieva, S D Sperry, Karan Sachdeva, Sanobar Jaka","doi":"10.1155/crps/5528976","DOIUrl":"10.1155/crps/5528976","url":null,"abstract":"Schizophrenia-spectrum disorders are characterized by psychotic symptoms, including hallucinations, delusions, and disorganized thinking. Schneider's first-rank symptoms (FRS)-including thought broadcasting and experiences of external control-are clinically salient but not ergonomic and require careful differential diagnosis. The emergence of new-onset psychosis in midlife, particularly in individuals without prior psychotic history, warrants a broad biopsychosocial evaluation. We present the case of a 47-year-old male with chronic major depressive disorder and complex developmental trauma who developed abrupt FRS-like phenomena (prominently thought broadcasting) and auditory hallucinations following a period marked by (1) severe pneumonia with lung abscess, (2) escalating anxiety and depressive distress, (3) exposure to substances including reported synthetic cannabinoids (\"Spice\") with a urine toxicology positive for amphetamines, and (4) neuromodulation via 20 sessions of transcranial magnetic stimulation (TMS). Concurrently, the patient experienced a severe psychosocial/legal stressor (investigation related to child sexual exploitation material), associated with profound shame and fear. Rather than attributing symptoms to a single trigger, this case highlights a convergence model-medical inflammation, substance toxicity, trauma-related vulnerability, and acute legal stress-potentially disrupting cerebral homeostasis and precipitating psychosis and suicidality. Treatment included discontinuation of TMS, pharmacologic stabilization, and intensive psychotherapy, with partial remission of psychotic symptoms. There is a need for structured monitoring for emergent psychosis and multidimensional suicide risk in high-risk patients receiving neuromodulation.","PeriodicalId":9631,"journal":{"name":"Case Reports in Psychiatry","volume":"2026 ","pages":"5528976"},"PeriodicalIF":0.0,"publicationDate":"2026-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12963453/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147376127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Managing Recurrent Postictal Worsening of Psychosis in Clozapine-Treated Schizophrenia: A Case Report. 氯氮平治疗的精神分裂症患者精神病复发后恶化的处理：一例报告。

Case Reports in Psychiatry Pub Date : 2026-02-23 eCollection Date: 2026-01-01 DOI: 10.1155/crps/8712049

Rafae Alam, Robert O Cotes, David R Goldsmith

{"title":"Managing Recurrent Postictal Worsening of Psychosis in Clozapine-Treated Schizophrenia: A Case Report.","authors":"Rafae Alam, Robert O Cotes, David R Goldsmith","doi":"10.1155/crps/8712049","DOIUrl":"https://doi.org/10.1155/crps/8712049","url":null,"abstract":"Postictal worsening of psychosis can be described as the development or exacerbation of psychotic symptoms following a seizure. Patients on clozapine for treatment-resistant schizophrenia are at an increased risk for seizures and subsequent postictal worsening of psychosis. Because patients with schizophrenia may experience ongoing psychotic symptoms, it may be difficult to appreciate the development of postictal worsening of psychosis in these patients. We present the case of a 49-year-old woman with a longstanding history of schizophrenia treated with clozapine who presented to the emergency department (ED) after experiencing a seizure. In the following days, she and her mother reported an exacerbation of psychotic symptoms, which was ultimately attributed to a postictal worsening of psychosis. She was successfully treated after being prescribed an increased nightly dose of clozapine. This dose was eventually reduced to the usual dose she had been taking prior to the postictal exacerbation of psychosis. We also briefly describe a recurrent episode the patient experienced approximately 1 year later. This case contributes to the literature by offering one potential management strategy for postictal worsening of psychosis in a patient with a primary psychotic disorder.","PeriodicalId":9631,"journal":{"name":"Case Reports in Psychiatry","volume":"2026 ","pages":"8712049"},"PeriodicalIF":0.0,"publicationDate":"2026-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12927945/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147282372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Compulsory Psychiatric Treatment at Home in the Netherlands: A Case Report. 荷兰家庭强制精神病治疗：一个案例报告。

Case Reports in Psychiatry Pub Date : 2026-02-23 eCollection Date: 2026-01-01 DOI: 10.1155/crps/4088726

D A de Waardt, G A M Widdershoven, M H C M Laan, R Favie, C L Mulder

{"title":"Compulsory Psychiatric Treatment at Home in the Netherlands: A Case Report.","authors":"D A de Waardt, G A M Widdershoven, M H C M Laan, R Favie, C L Mulder","doi":"10.1155/crps/4088726","DOIUrl":"https://doi.org/10.1155/crps/4088726","url":null,"abstract":"An important aim of the new mental health act implemented in the Netherlands in 2020 was to shift the focus from hospitalization to treatment. The act provides an option for patients' compulsory treatment at home (CTH). Unlike compulsory community treatment (CCT), which allows mental health workers to hospitalize patients involuntarily if they do not comply with treatment. CTH is not provided elsewhere in the world. This case report concerns a patient who, to avoid hospitalization, received CTH in the form of compulsory medication and was able to recover at home. Retrospectively, she and the mental health team both positively evaluated this use of CTH. The parties involved all concluded that CTH restricted the patient's autonomy less than hospitalization, it did not influence the therapeutic relationship, and the CTH could be delivered in a way that it did not compromise participants' safety. This case report shows that, in some situations, CTH can avoid hospitalization. Care should nonetheless be taken to assess its appropriateness, to discuss any preconditions, and to evaluate the use of compulsory treatment in dialog with the patient and significant others.","PeriodicalId":9631,"journal":{"name":"Case Reports in Psychiatry","volume":"2026 ","pages":"4088726"},"PeriodicalIF":0.0,"publicationDate":"2026-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12927947/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147282379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction to "Exploring Van Gogh Syndrome: A Case Report on Schizoaffective Disorder and Self-Harm". 更正“探索梵高综合症：精神分裂情感性障碍与自残个案报告”。

Case Reports in Psychiatry Pub Date : 2026-02-22 eCollection Date: 2026-01-01 DOI: 10.1155/crps/9865295

引用次数: 0

Autism and Its Lookalikes: A Case Report of a Child Whose Autism Diagnosis No Longer Fit Years Later. 自闭症及其相似之处：一个儿童的自闭症诊断多年后不再适合的病例报告。

Case Reports in Psychiatry Pub Date : 2026-02-09 eCollection Date: 2026-01-01 DOI: 10.1155/crps/8279416

Elizabeth Kim, Ji Su Hong

引用次数: 0

Persistent Tremor in Bipolar Disorder: A Case Report of Idiopathic Parkinson's Disease Superimposed on Lithium and Antipsychotic Effects. 双相情感障碍的持续性震颤：特发性帕金森病叠加锂和抗精神病药物的一例报告。

Case Reports in Psychiatry Pub Date : 2026-02-06 eCollection Date: 2026-01-01 DOI: 10.1155/crps/5580753

Ethan Jetter, Daisy Valle, Diego Nolasco, Brent Carr

{"title":"Persistent Tremor in Bipolar Disorder: A Case Report of Idiopathic Parkinson's Disease Superimposed on Lithium and Antipsychotic Effects.","authors":"Ethan Jetter, Daisy Valle, Diego Nolasco, Brent Carr","doi":"10.1155/crps/5580753","DOIUrl":"10.1155/crps/5580753","url":null,"abstract":"We report a 58-year-old woman with bipolar I disorder on long-term lithium and aripiprazole who developed a progressive asymmetric resting tremor and rigidity. Despite stopping both agents, the tremor persisted for more than a year. Dopamine transporter imaging showed reduced uptake in the left putamen, confirming idiopathic Parkinson's disease (PD) with superimposed drug-induced parkinsonism (DIP). Management included discontinuing lithium, switching aripiprazole to quetiapine to limit motor worsening, and starting carbidopa-levodopa. Motor symptoms improved, but hypomanic symptoms emerged and required psychiatric dose adjustments, while apathy remained prominent. The case illustrates diagnostic overshadowing in bipolar disorder (BD) and highlights two practical lessons. When parkinsonian signs are atypical or persist after medication changes, consider idiopathic PD rather than attributing symptoms to side effects. Care is best delivered through close collaboration between psychiatry and neurology to balance dopaminergic therapy with mood stabilization.","PeriodicalId":9631,"journal":{"name":"Case Reports in Psychiatry","volume":"2026 ","pages":"5580753"},"PeriodicalIF":0.0,"publicationDate":"2026-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12878793/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146140848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0