Case Reports in Psychiatry最新文献

{"title":"When You Hear Hoofbeats, It May Still Be the Medication: A Case of Aripiprazole-Induced Hypersexuality Masquerading as Psychiatric Decompensation.","authors":"Nana Cudjoe, Terrance C Jenkins, Brittany Stallworth, Cansery Kathomi Mwai, Alainia Morgan","doi":"10.1155/crps/2595434","DOIUrl":"https://doi.org/10.1155/crps/2595434","url":null,"abstract":"<p><p>Aripiprazole has a known association with impulse-control disorders (ICDs), yet these adverse effects are frequently underrecognized and misattributed to psychiatric decompensation, particularly in women. We report a case of a 27-year-old African American woman with schizoaffective disorder who developed marked, new-onset hypersexual behavior temporally associated with aripiprazole. Aripiprazole accounts for a majority of ICDs reported among this class of antipsychotics, likely due to its D2/D3 partial agonism. This case highlights the critical need for clinicians to maintain a high index of suspicion for medication-induced ICDs when patients develop new impulsive or compulsive behaviors.</p>","PeriodicalId":9631,"journal":{"name":"Case Reports in Psychiatry","volume":"2026 ","pages":"2595434"},"PeriodicalIF":0.0,"publicationDate":"2026-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13695863/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149263130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cariprazine Augmentation and Sustained Remission of Physical Aggression in Clozapine-Treated Treatment-Resistant Schizophrenia: A Case Report.","authors":"Juhani Leijala, Antti Mustonen","doi":"10.1155/crps/9943329","DOIUrl":"https://doi.org/10.1155/crps/9943329","url":null,"abstract":"<p><p>Persistent aggression may occur in treatment-resistant schizophrenia (TRS) despite long-term clozapine treatment and multiple augmentation strategies. We describe a male patient in his sixties with a decades-long history of schizophrenia who required prolonged psychiatric inpatient care because of recurrent, unpredictable physical assaults toward other patients, staff, relatives, and police. This included treatment at a state forensic psychiatric hospital because of treatment complexity and safety concerns, not forensic legal status. Aggression persisted during adequately monitored high-dose clozapine treatment and several augmentation strategies. The last documented physical assault occurred in October 2021. Cariprazine 1.5 mg/day was initiated in November 2021, primarily for longstanding negative symptoms. Within approximately seven weeks, mood and participation in communal ward activities improved. No further physical assaults were documented during more than 4 years of follow-up. The patient subsequently transitioned to voluntary treatment and supported housing. Later somatic illnesses, temporary interruptions of oral medication, and substantial fluctuations in clozapine serum concentrations were not followed by renewed physical aggression. This case describes a prolonged temporal association between cariprazine augmentation and the absence of recurrent physical assaults, but the single-case design, episodic pretreatment course, concomitant treatment changes, and absence of standardized ratings preclude causal inference.</p>","PeriodicalId":9631,"journal":{"name":"Case Reports in Psychiatry","volume":"2026 ","pages":"9943329"},"PeriodicalIF":0.0,"publicationDate":"2026-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13696002/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149263079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sequential EMDR and CBT for Small-t Trauma in an Adult With Autism Spectrum Disorder: A Clinical Case Report.","authors":"Keita Kawai, Michie Ishida, Yutaka Omura","doi":"10.1155/crps/4899601","DOIUrl":"https://doi.org/10.1155/crps/4899601","url":null,"abstract":"<p><p>This clinical case report describes a sequential combination of eye movement desensitization and reprocessing (EMDR) therapy and cognitive behavioral therapy (CBT) for small-t trauma in an adult patient with autism spectrum disorder (ASD). Individuals with ASD could be vulnerable to the accumulation of nonlife-threatening adverse interpersonal experiences, often described as small-t trauma, which can contribute to anxiety, depressive symptoms, and social withdrawal. The patient was a 25-year-old woman with ASD who presented with flashback-like symptoms and social anxiety related to distressing childhood and adolescent experiences with family members and school-related experiences. Treatment consisted of EMDR sessions targeting these traumatic memories, followed by CBT focused on cognitive restructuring and adaptive interpersonal coping. Across treatment, traumatic stress, anxiety, and depressive symptoms decreased, and the patient transitioned from unemployment to employment through a disability employment scheme. This case illustrates how EMDR may reduce trauma-related distress sufficiently to allow subsequent CBT work on current interpersonal difficulties. Although causal conclusions cannot be drawn from a single case, this report suggests that EMDR adapted to the characteristics of ASD, followed by CBT, may be clinically useful for addressing small-t trauma in adults with ASD.</p>","PeriodicalId":9631,"journal":{"name":"Case Reports in Psychiatry","volume":"2026 ","pages":"4899601"},"PeriodicalIF":0.0,"publicationDate":"2026-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13691431/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149263065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hyperactive Delirium Temporally Associated With Hydroxyzine in a Child With Succinic Semialdehyde Dehydrogenase Deficiency Presenting With Psychotic Symptoms: A Case Report.","authors":"Musa Yilanli, Colton Olexa, Bianca Zapanta","doi":"10.1155/crps/3543154","DOIUrl":"10.1155/crps/3543154","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Succinic semialdehyde dehydrogenase deficiency (SSADHD) is a rare autosomal recessive disorder of gamma-aminobutyric acid (GABA) metabolism caused by biallelic variants in ALDH5A1. The phenotype includes developmental delay, intellectual disability, seizures, sleep disturbance, anxiety, and other neurobehavioral symptoms. Psychotic symptoms are increasingly recognized in SSADHD but remain uncommon and incompletely characterized in children. In medically and neurodevelopmentally vulnerable patients, acute psychiatric decompensation may also be complicated by delirium, especially when severe sleep-wake disruption, poor intake, constipation, metabolic stress, and potentially deliriogenic medications are present.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Case presentation: &lt;/strong&gt;We describe a 12-year-old girl with intellectual disability, global developmental delay, abnormal prior neuroimaging, abnormal EEG findings, progressive weight loss, reduced oral intake, insomnia, and new-onset auditory and visual hallucinations. During hospitalization, she developed a fluctuating neurobehavioral syndrome marked by impaired attention, severe sleep-wake disruption, increased startle response, inconsolability, agitation, perceptual disturbances, and waxing and waning behavioral organization. These findings supported hyperactive delirium superimposed on psychotic symptoms rather than isolated psychosis. Hydroxyzine was ordered as 25 mg by mouth every 6 h as needed and was administered six times from hospital day 5 through early hospital day 7. The medication provided mixed short-term anxiolytic and sedating benefits but did not meaningfully reduce hallucinations or restore normal sleep. After hydroxyzine exposure, impaired attention, profound sleep-wake dysregulation, inconsolability, increased startle response, fluctuating agitation, and behavioral disorganization remained prominent, raising concern that hydroxyzine may have contributed to persistence or worsening of the acute confusional state in the setting of severe sleep deprivation, poor oral intake, constipation, neurologic vulnerability, and underlying SSADHD. Hydroxyzine was discontinued, and low-dose quetiapine was initiated together with environmental sleep-wake and reorientation interventions. Sleep, appetite, oral intake, and behavioral regulation subsequently improved. Diagnostic evaluation supported SSADHD, including elevated urinary 4-hydroxybutyric acid, characteristic MRI abnormalities of the globi pallidi and dentate nuclei, and a homozygous ALDH5A1 missense variant, NM_001080.3:c.434A &gt;G (p.Glu145Gly), formally classified as a variant of uncertain significance but considered clinically concordant with the diagnosis.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;This case highlights SSADHD as an important consideration in children presenting with acute psychotic symptoms and altered mental status. It also underscores the importance of distinguishing psychotic symptoms from superimposed delirium in","PeriodicalId":9631,"journal":{"name":"Case Reports in Psychiatry","volume":"2026 ","pages":"3543154"},"PeriodicalIF":0.0,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13647299/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149135178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rapunzel Syndrome as a Complication of Childhood-Onset Trichotillomania.","authors":"Ruchika Darapaneni, Zachary Nobile, Regina Reed, Eduardo Espiridion, John Gurski","doi":"10.1155/crps/6542586","DOIUrl":"https://doi.org/10.1155/crps/6542586","url":null,"abstract":"<p><strong>Introduction: </strong>Rapunzel syndrome is a rare and potentially life-threatening complication of trichotillomania with trichophagia, characterized by the extension of a gastric trichobezoar into the small intestine. Diagnosis is frequently delayed due to nonspecific presenting symptoms, and management requires both surgical intervention and psychiatric treatment to prevent recurrence.</p><p><strong>Patient case: </strong>We report the case of a 22-year-old woman with childhood-onset trichotillomania and trichophagia who presented with nonspecific abdominal complaints. Imaging revealed a large intragastric mass, and endoscopy confirmed a dense trichobezoar extending through the pylorus into the duodenum, consistent with Rapunzel syndrome. Endoscopic removal was unsuccessful, and the patient underwent open gastrotomy with intact removal of the mass without complication. Psychiatric evaluation revealed a long history of hairpulling and ingestion behaviors beginning in early childhood, with limited prior psychiatric treatment.</p><p><strong>Discussion: </strong>This case illustrates the cumulative medical risk of untreated chronic, childhood-onset trichotillomania with trichophagia, particularly when hair-ingestion behaviors persist without sustained trichotillomania-specific behavioral treatment. Its contribution to the literature lies in the detailed longitudinal psychiatric characterization of symptom progression and the consideration of comorbid attention-deficit/hyperactivity disorder (ADHD), which may be relevant to the hairpulling and ingestion behaviors themselves through attentional dysregulation, impulsivity, impaired inhibitory control, and automaticity.</p><p><strong>Conclusion: </strong>Rapunzel syndrome represents a severe consequence of chronic hairpulling and ingestion behaviors. Early identification of trichophagia, psychiatric referral, and sustained behavioral treatment are essential to prevent progression to life-threatening complications and to reduce recurrence following surgical intervention.</p>","PeriodicalId":9631,"journal":{"name":"Case Reports in Psychiatry","volume":"2026 ","pages":"6542586"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13628702/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149104543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Suicide by Proxy: A Psychoanalytic Hypothesis Illustrated by Three Forensic Case Reports.","authors":"Yasir Karkosh, Badar Al Habsi, Salim Al-Huseini","doi":"10.1155/crps/6643923","DOIUrl":"10.1155/crps/6643923","url":null,"abstract":"<p><p>This paper proposes the hypothesis of Suicide by Proxy, a psychodynamic formulation suggesting that certain acts of homicide may represent displaced manifestations of suicidal intent. Drawing on three retrospectively analysed forensic psychiatric cases involving individuals with psychotic disorders and documented suicidal ideation, this study illustrates how, from a psychoanalytic perspective, unresolved Oedipal dynamics, harsh punitive superego processes and internalised aggression may contribute to homicidal behaviour. The cases are interpreted as compatible with the hypothesis that, when direct self-harm is psychologically inhibited, suicidal impulses may be redirected towards a symbolic other, such that homicide may function as a proxy for self-destruction. Although based on a small, purposively selected case series and therefore hypothesis-generating rather than confirmatory, this formulation offers a novel perspective on the relationship between suicidality and homicidal behaviour. Rather than proposing a new diagnostic entity or established causal mechanism, the study presents a psychodynamic hypothesis intended to stimulate further clinical and empirical investigation of the relationship between self-directed and other-directed aggression.</p>","PeriodicalId":9631,"journal":{"name":"Case Reports in Psychiatry","volume":"2026 ","pages":"6643923"},"PeriodicalIF":0.0,"publicationDate":"2026-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13615509/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149058510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electroconvulsive Therapy for the Treatment of Protracted Resistant Agitated Psychosis With Comorbid Delirium in the Intensive Care Unit: A Case Report.","authors":"Mohammad Javed, Jack Noto, Allison Trabold, Renzmark Vallesteros, Muhammad Abbas","doi":"10.1155/crps/6633644","DOIUrl":"10.1155/crps/6633644","url":null,"abstract":"<p><p>Delirium is a common and debilitating condition in the intensive care unit (ICU), leading to prolonged hospital stays, increased mortality, and significant morbidity. While nonpharmacologic interventions are typically the first line of treatment, pharmacologic approaches such as antipsychotics are often used to manage agitation, with variable efficacy. This case report describes a patient with agitated psychosis with comorbid delirium in the ICU, who failed to respond to multiple trials of antipsychotic medications and experienced a prolonged ICU stay. Electroconvulsive therapy (ECT) was initiated, with subsequent improvement in the patient's symptoms, including the resolution of agitation and delirium. This case underscores the need for early consideration of ECT in treatment-resistant agitated psychosis with comorbid delirium and highlights the potential benefits of this approach, particularly in patients with complicated or multifactorial presentations.</p>","PeriodicalId":9631,"journal":{"name":"Case Reports in Psychiatry","volume":"2026 ","pages":"6633644"},"PeriodicalIF":0.0,"publicationDate":"2026-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13613436/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149058485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abrupt Termination of Severe Treatment Refractory Neuropsychiatric Symptoms in a Patient Treated With Rituximab-A Case Report.","authors":"Daniel Albert, Brian Rosen, Juliette Madan","doi":"10.1155/crps/6717967","DOIUrl":"10.1155/crps/6717967","url":null,"abstract":"<p><p>A 65-year-old woman presented to a joint rheumatology, neurology, and psychiatry clinic with subacute onset of severe neuropsychiatric symptoms that began 2 years prior. The symptomatology had been dominated by paranoid ideation, withdrawal from family, and cognitive changes. Over the previous 2-year period the patient required inpatient psychiatric care three times with provisional diagnoses, including major depressive disorder with psychotic features, schizophrenia, and late-onset schizophrenia. Pharmacologic treatments consisted of multiple trials of different antidepressants and antipsychotics, eventually with a trial of clozapine without notable benefit and further worsening of symptoms. Ultimately the patient was unable to perform her activities of daily living (ADL) independently. Past medical history was notable for pernicious anemia. An extensive evaluation was notable for antibodies to intrinsic factor consistent with pernicious anemia and low-titer antiphospholipid antibodies. Magnetic resonance imaging (MRI), electroencephalography (EEG), and cerebrospinal fluid (CSF) evaluations were all unrevealing. Neuropsychologic testing demonstrated difficulties with executive function and semantic retrieval along with ADL deficits meeting criteria for major neurocognitive disorder (MNCD) of uncertain etiology. A multidisciplinary evaluation ultimately identified a possible systemic lupus erythematosus (SLE)-related process. The patient received two 1-g infusions of rituximab. Approximately 3 weeks later she experienced a substantial reduction in her complex neuropsychiatric symptoms, and within 6 months she almost completely returned to her premorbid level of functioning. This case illustrates an atypical presentation of treatment-resistant neuropsychiatric and neurocognitive symptoms that benefitted from comprehensive, multidisciplinary evaluation and treatment. When frank antibody-positive autoimmune encephalitis and antibody-negative autoimmune encephalitis have been excluded, clinicians should consider underlying emerging systemic autoimmune disease, for example, SLE as a potential cause of psychosis and other severe neuropsychiatric manifestations, prompting further diagnostic workup and treatment strategies, including immunotherapy.</p>","PeriodicalId":9631,"journal":{"name":"Case Reports in Psychiatry","volume":"2026 ","pages":"6717967"},"PeriodicalIF":0.0,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13587140/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149008049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From Falls to Frontal Lobe Dysfunction: A Case Report on the Neurodevelopmental Impact of Pediatric Traumatic Brain Injury.","authors":"Manuel Glauco Carbone, Alessandro Bellini, Rossella Miccichè, Beniamino Tripodi, Bruno Pacciardi, Donatella Marazziti, Icro Maremmani, Roberta Rizzato, Giulia Gastaldello, Luca Mazzetto, Claudia Tagliarini","doi":"10.1155/crps/4751775","DOIUrl":"10.1155/crps/4751775","url":null,"abstract":"<p><p>This case report examines the presentation and management of late-onset frontal lobe syndrome (FLS) following early-life traumatic brain injury (TBI). It illustrates the diagnostic challenges of this condition and the rationale for an individualized pharmacological approach. The case focuses on a young adult male who sustained two head injuries in early childhood, the more severe being a frontotemporal trauma at age 5, with debilitating FLS symptoms, including marked emotional lability and executive function deficits, emerging at age 17. This delayed presentation, characteristic of late-onset FLS, often complicates diagnosis and treatment. Prior to referral, the patient experienced significant interpersonal conflicts, strained family dynamics, and an inability to maintain employment due to his FLS symptoms. Recognizing the profound impact of his condition, a tailored pharmacological intervention strategy was implemented, focusing on mood stabilization and emotional regulation. This approach utilized mood stabilizers, specifically lithium and valproic acid, alongside the selective serotonin reuptake inhibitor (SSRI) paroxetine. Over follow-up, the patient demonstrated gradual improvements across multiple domains. His emotional lability decreased, alongside improved interpersonal relationships, reduced family conflict, and a greater capacity for sustained occupational engagement. Additionally, he reported subjective improvements in his overall quality of life, experiencing greater emotional well-being and increased self-efficacy. This case highlights the importance of considering long-term neurological consequences of TBI, even in the absence of immediate symptoms. It also illustrates the potential value of tailored pharmacological management within a broader multidisciplinary approach.</p>","PeriodicalId":9631,"journal":{"name":"Case Reports in Psychiatry","volume":"2026 ","pages":"4751775"},"PeriodicalIF":0.0,"publicationDate":"2026-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13584333/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148988191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lamotrigine-Associated Toxic Epidermal Necrolysis in a Southeast Asian Female: A Case Report Highlighting Sex and Ancestry-Related Susceptibility.","authors":"Sydney Christopherson, Naomi Graham, Jonathan Wirjo","doi":"10.1155/crps/2560198","DOIUrl":"https://doi.org/10.1155/crps/2560198","url":null,"abstract":"<p><strong>Background: </strong>Stevens-Johnson syndrome (SJS) is a known, but rare adverse effect of Lamotrigine, occurring in less than 0.1% of the population. Rapid dose titrations of Lamotrigine, an antiepileptic used off-label for the treatment of bipolar disorder, have been shown to increase the risk of SJS, and in even rarer cases, progression to toxic epidermal necrolysis (TEN), which currently has too few cases to report an estimated incidence. Data suggest that additional factors, including female sex and certain HLA alleles associated with East and Southeast Asian ancestries, may be associated with increased risk of Lamotrigine-induced SJS/TEN.</p><p><strong>Case presentation: </strong>This case presents a 26-year-old Southeast Asian female with bipolar I disorder who developed SJS shortly after her Lamotrigine dose was titrated appropriately from 50 milligrams (mg) to 100 mg daily, which rapidly progressed to TEN. The patient received treatment, including steroids, intravenous (IV) immunoglobulin, and surgical debridement, and was discharged home in stable condition after 8 days.</p><p><strong>Conclusion: </strong>This case prompts consideration of sex and ancestry when identifying high-risk populations taking Lamotrigine. Continued research into sex- and ancestry-based pharmacogenomics may reduce the incidence of these life-threatening reactions.</p>","PeriodicalId":9631,"journal":{"name":"Case Reports in Psychiatry","volume":"2026 ","pages":"2560198"},"PeriodicalIF":0.0,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13578926/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148988186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}