{"title":"超越冒名顶替者:解读Capgras综合征和多学科管理。","authors":"Manuel Glauco Carbone, Tommaso Merati, Rossella Miccichè, Camilla Callegari, Beniamino Tripodi, Claudia Tagliarini, Icro Maremmani, Donatella Marazziti","doi":"10.1155/crps/5541100","DOIUrl":null,"url":null,"abstract":"<p><p>Capgras syndrome (CS) presents a unique diagnostic and management challenge, particularly when associated with neurodegenerative conditions. This case report describes a 73-year-old female diagnosed with Lewy body dementia (LBD) who developed CS, manifesting as the delusional belief that her deceased husband had been replaced by an imposter. The clinical presentation was complex, including pronounced sleep disturbances, cognitive decline, behavioral anomalies, and visual hallucinations, necessitating a thorough differential diagnosis process. We detail the patient's history, clinical findings, and the investigations undertaken, including brain imaging and cognitive assessments. The management approach involved a personalized treatment plan integrating Lithium sulfate, Citalopram, and Lurasidone, alongside psychosocial interventions. While a partial improvement was observed, the case underscores the complexities of managing CS in the context of LBD, highlighting the need for tailored and multidisciplinary approaches to care. This case contributes to the limited literature on CS in LBD and provides practical insights for clinicians managing similar presentations.</p>","PeriodicalId":9631,"journal":{"name":"Case Reports in Psychiatry","volume":"2025 ","pages":"5541100"},"PeriodicalIF":0.0000,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12360872/pdf/","citationCount":"0","resultStr":"{\"title\":\"Beyond the Imposter: Deciphering Capgras Syndrome and Multidisciplinary Management.\",\"authors\":\"Manuel Glauco Carbone, Tommaso Merati, Rossella Miccichè, Camilla Callegari, Beniamino Tripodi, Claudia Tagliarini, Icro Maremmani, Donatella Marazziti\",\"doi\":\"10.1155/crps/5541100\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Capgras syndrome (CS) presents a unique diagnostic and management challenge, particularly when associated with neurodegenerative conditions. This case report describes a 73-year-old female diagnosed with Lewy body dementia (LBD) who developed CS, manifesting as the delusional belief that her deceased husband had been replaced by an imposter. The clinical presentation was complex, including pronounced sleep disturbances, cognitive decline, behavioral anomalies, and visual hallucinations, necessitating a thorough differential diagnosis process. We detail the patient's history, clinical findings, and the investigations undertaken, including brain imaging and cognitive assessments. The management approach involved a personalized treatment plan integrating Lithium sulfate, Citalopram, and Lurasidone, alongside psychosocial interventions. While a partial improvement was observed, the case underscores the complexities of managing CS in the context of LBD, highlighting the need for tailored and multidisciplinary approaches to care. This case contributes to the limited literature on CS in LBD and provides practical insights for clinicians managing similar presentations.</p>\",\"PeriodicalId\":9631,\"journal\":{\"name\":\"Case Reports in Psychiatry\",\"volume\":\"2025 \",\"pages\":\"5541100\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-08-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12360872/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Case Reports in Psychiatry\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1155/crps/5541100\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Case Reports in Psychiatry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1155/crps/5541100","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
Beyond the Imposter: Deciphering Capgras Syndrome and Multidisciplinary Management.
Capgras syndrome (CS) presents a unique diagnostic and management challenge, particularly when associated with neurodegenerative conditions. This case report describes a 73-year-old female diagnosed with Lewy body dementia (LBD) who developed CS, manifesting as the delusional belief that her deceased husband had been replaced by an imposter. The clinical presentation was complex, including pronounced sleep disturbances, cognitive decline, behavioral anomalies, and visual hallucinations, necessitating a thorough differential diagnosis process. We detail the patient's history, clinical findings, and the investigations undertaken, including brain imaging and cognitive assessments. The management approach involved a personalized treatment plan integrating Lithium sulfate, Citalopram, and Lurasidone, alongside psychosocial interventions. While a partial improvement was observed, the case underscores the complexities of managing CS in the context of LBD, highlighting the need for tailored and multidisciplinary approaches to care. This case contributes to the limited literature on CS in LBD and provides practical insights for clinicians managing similar presentations.