Beyond the Imposter: Deciphering Capgras Syndrome and Multidisciplinary Management.

Q4 Medicine
Case Reports in Psychiatry Pub Date : 2025-08-11 eCollection Date: 2025-01-01 DOI:10.1155/crps/5541100
Manuel Glauco Carbone, Tommaso Merati, Rossella Miccichè, Camilla Callegari, Beniamino Tripodi, Claudia Tagliarini, Icro Maremmani, Donatella Marazziti
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引用次数: 0

Abstract

Capgras syndrome (CS) presents a unique diagnostic and management challenge, particularly when associated with neurodegenerative conditions. This case report describes a 73-year-old female diagnosed with Lewy body dementia (LBD) who developed CS, manifesting as the delusional belief that her deceased husband had been replaced by an imposter. The clinical presentation was complex, including pronounced sleep disturbances, cognitive decline, behavioral anomalies, and visual hallucinations, necessitating a thorough differential diagnosis process. We detail the patient's history, clinical findings, and the investigations undertaken, including brain imaging and cognitive assessments. The management approach involved a personalized treatment plan integrating Lithium sulfate, Citalopram, and Lurasidone, alongside psychosocial interventions. While a partial improvement was observed, the case underscores the complexities of managing CS in the context of LBD, highlighting the need for tailored and multidisciplinary approaches to care. This case contributes to the limited literature on CS in LBD and provides practical insights for clinicians managing similar presentations.

超越冒名顶替者:解读Capgras综合征和多学科管理。
Capgras综合征(CS)提出了一个独特的诊断和管理挑战,特别是当与神经退行性疾病相关时。本病例报告描述了一名73岁的女性,被诊断为路易体痴呆(LBD),她发展为CS,表现为妄想,认为她已故的丈夫被一个冒名顶替者取代。临床表现复杂,包括明显的睡眠障碍、认知能力下降、行为异常和视觉幻觉,需要彻底的鉴别诊断过程。我们详细介绍了患者的病史、临床表现和所进行的调查,包括脑成像和认知评估。管理方法包括个性化的治疗计划,包括硫酸锂、西酞普兰和鲁拉西酮,以及社会心理干预。虽然观察到部分改善,但该病例强调了在LBD背景下管理CS的复杂性,突出了量身定制和多学科治疗方法的必要性。本病例对LBD中CS的有限文献有所贡献,并为临床医生管理类似的表现提供了实践见解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Case Reports in Psychiatry
Case Reports in Psychiatry Medicine-Psychiatry and Mental Health
CiteScore
1.00
自引率
0.00%
发文量
49
审稿时长
12 weeks
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