Case Reports in Dermatological Medicine最新文献_第4页

Drug-Induced Erythema Multiforme. 药物诱导的多型红斑。

Case Reports in Dermatological Medicine Pub Date : 2023-10-23 eCollection Date: 2023-01-01 DOI: 10.1155/2023/8706006

Peeyush Shivhare, Naqoosh Haidry, Anka Sharma, Deepali Agrawal, Abhishek Gupta, Shalini Subramanyam

引用次数: 0

Pemphigus Foliaceus after COVID-19 Vaccination: A Report of Two Cases. 新冠肺炎疫苗接种后对叶天疱疮：两例报告。

Case Reports in Dermatological Medicine Pub Date : 2023-10-19 eCollection Date: 2023-01-01 DOI: 10.1155/2023/1218388

Nguyen Nhat Pham, Thuy Thi Phan Nguyen, Thao Thi Phuong Vu, Hao Trong Nguyen

引用次数: 0

Reactive Granulomatous Dermatitis in a Child with Acute Lymphoblastic Leukemia. 儿童急性淋巴细胞白血病反应性肉芽肿性皮炎。

Case Reports in Dermatological Medicine Pub Date : 2023-10-12 eCollection Date: 2023-01-01 DOI: 10.1155/2023/3428162

Hannah C Tolson, Mariana McCune, Miranda Yousif, David DiCaudo, Elizabeth Dupuy

引用次数: 0

Clouston Syndrome: Report of a Jordanian Family with GJB6 Gene Mutation. Clouston综合征：一个患有GJB6基因突变的约旦家庭的报告。

Case Reports in Dermatological Medicine Pub Date : 2023-10-12 eCollection Date: 2023-01-01 DOI: 10.1155/2023/5577379

Rand Murshidi, Heba Al-Lala

{"title":"Clouston Syndrome: Report of a Jordanian Family with GJB6 Gene Mutation.","authors":"Rand Murshidi, Heba Al-Lala","doi":"10.1155/2023/5577379","DOIUrl":"10.1155/2023/5577379","url":null,"abstract":"Ectodermal dysplasias (ED) encompass a collection of conditions wherein the development of two or more structures derived from the ectoderm exhibits abnormal patterns. One example of such a rarity within the spectrum of ectodermal dysplasias is hidrotic ectodermal dysplasia, also known as Clouston syndrome. This particular variant is distinguished by a triad of clinical characteristics, which encompass partial-to-complete alopecia, nail dystrophy, and palmoplantar hyperkeratosis. It stands as a scarcely encountered autosomal-dominant inherited disorder, resulting from a mutation in the GJB6 gene that encodes the gap junction protein connexin 30. We hereby document the case of a forty-five-year-old Jordanian woman who presented with alopecia affecting the scalp, eyebrows, and eyelashes, in addition to nail dystrophy. Interestingly, she did not manifest palmoplantar keratoderma. It is worth mentioning that several members of her extended family also manifested similar clinical features. Subsequent genetic testing conclusively established the diagnosis of Clouston syndrome. In light of this diagnosis, comprehensive counseling was extended to the patient.","PeriodicalId":9630,"journal":{"name":"Case Reports in Dermatological Medicine","volume":"2023 ","pages":"5577379"},"PeriodicalIF":0.0,"publicationDate":"2023-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586907/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49688867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Atypical Mal de Meleda in a Hispanic Patient. 一名西班牙裔患者的非典型Mal de Meleda。

Case Reports in Dermatological Medicine Pub Date : 2023-09-14 eCollection Date: 2023-01-01 DOI: 10.1155/2023/6640311

Mónica Guevara, Michelle Mafla, Camila Miño

{"title":"Atypical Mal de Meleda in a Hispanic Patient.","authors":"Mónica Guevara, Michelle Mafla, Camila Miño","doi":"10.1155/2023/6640311","DOIUrl":"https://doi.org/10.1155/2023/6640311","url":null,"abstract":"Mal de Meleda (MDM) is a rare autosomal palmoplantar keratoderma (PPK) skin disorder (estimated incidence of 1 per 100,000 people) commonly associated with consanguinity and early childhood onset. MDM is characterized by bilateral diffusion of PPK plaques with delimited yellowish lesions that transgredien to the dorsum of the hands and feet. Additional features include nail dystrophy, lichenoid lesions, hyperhidrotic maceration, involvement of the knees and elbows, malodor, fungal superinfections, and digital constrictions. A male patient aged 42 years presented with asymptomatic, chronic, and diffused PPK lesions that progressed to the dorsal surface of the hands and feet, along with knees and elbows involvement. On clinical examination, asymmetrical lesions were observed on the hands, the left palm with yellowish waxy hyperkeratotic plaques, and the right palm with erythematous scaling and hyperkeratotic interphalangeal rings. The soles of the feet presented with yellow waxy hyperkeratotic plaques. In addition, nail dystrophy and loss of dermatoglyphics were observed. Initially, symptomatic topical treatment was established. However, owing to the lack of clinical response, a biopsy was performed, which revealed thickened corneal layer, acanthosis, spongiosis, and perivascular lymphohistiocytic infiltrate. MDM diagnosis was confirmed based on a personal history of consanguinity, clinical presentation with absence of systemic symptoms, and transgredien pattern of the lesions. Systemic treatment with low doses of isotretinoin (10 mg orally everyday) was initiated, and two months later, slight clinical improvement has been observed until date. The present case report describes MDM in a Hispanic patient, who presented with asymmetric PPK lesions on the hands and received isotretinoin treatment.","PeriodicalId":9630,"journal":{"name":"Case Reports in Dermatological Medicine","volume":"2023 ","pages":"6640311"},"PeriodicalIF":0.0,"publicationDate":"2023-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10513804/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41128930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Case of Leukocytoclastic Vasculitis and Associated Conjunctivitis Following MMR Vaccine Administration. 一例接种麻风腮疫苗后出现白细胞胞浆性血管炎和相关结膜炎的病例。

Case Reports in Dermatological Medicine Pub Date : 2023-02-06 eCollection Date: 2023-01-01 DOI: 10.1155/2023/9001287

Hana I Nazir, Aubrey A Hess, Abha Soni, Kathryn A Potter

{"title":"A Case of Leukocytoclastic Vasculitis and Associated Conjunctivitis Following MMR Vaccine Administration.","authors":"Hana I Nazir, Aubrey A Hess, Abha Soni, Kathryn A Potter","doi":"10.1155/2023/9001287","DOIUrl":"10.1155/2023/9001287","url":null,"abstract":"Introduction: Leukocytoclastic vasculitis (LCV) is a small-vessel vasculitis characterized by immune complex deposition in the walls of dermal capillaries and venules. With the COVID-19 pandemic, more adults are receiving the MMR vaccine, as it may enhance innate immune responses against COVID-19 infection. Here, we report a case of LCV and associated conjunctivitis arising in a patient secondary to immunization with the MMR vaccine.Methods and results: A 78-year-old man on lenalidomide therapy for multiple myeloma presented to an outpatient dermatology clinic with a two-day history of a painful rash consisting of scattered pink dermal papules on bilateral dorsal and palmar hands, as well as bilateral conjunctival erythema. Histopathological findings-which revealed an inflammatory infiltrate with papillary dermal edema, as well as nuclear dust within small blood vessel walls with extravasation of red blood cells-were most consistent with LCV. It then became known that the patient had received an MMR vaccine two weeks prior to the onset of the rash. The rash was resolved with the use of topical clobetasol ointment, and the patient's eyes were cleared as well.Conclusions: This is an interesting presentation of MMR vaccine-related LCV occurring only on the upper extremities with associated conjunctivitis. Had the patient's oncologist not known about the recent vaccination, it is likely that the treatment of his multiple myeloma would have been postponed or altered, as lenalidomide can also cause LCV.","PeriodicalId":9630,"journal":{"name":"Case Reports in Dermatological Medicine","volume":"2023 ","pages":"9001287"},"PeriodicalIF":0.0,"publicationDate":"2023-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925237/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10745501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Case for Doxycycline as an Effective Treatment for Confluent and Reticulated Papillomatosis (CARP). 强力霉素治疗融合网状乳头状瘤病一例。

Case Reports in Dermatological Medicine Pub Date : 2023-01-01 DOI: 10.1155/2023/6397272

Aishwarya Sharma, Deborah Moon, Dong Joo Kim

引用次数: 0

Metformin-Induced Generalized Bullous Fixed-Drug Eruption with a Positive Dechallenge-Rechallenge Test: A Case Report and Literature Review. 二甲双胍致广泛性大疱性固定药疹，脱挑战-再挑战试验阳性:1例报告及文献复习。

Case Reports in Dermatological Medicine Pub Date : 2023-01-01 DOI: 10.1155/2023/6353919

Bahareh Abtahi-Naeini, Tooba Momen, Rezvan Amiri, Parvin Rajabi, Fereshte Rastegarnasab

引用次数: 2

Multiple Squamous Cell Carcinoma in a Patient Using Skin Bleaching Products in Togo. 多哥一名使用皮肤漂白产品的患者的多发性鳞状细胞癌。

Case Reports in Dermatological Medicine Pub Date : 2023-01-01 DOI: 10.1155/2023/8002896

Abas Mouhari-Toure, Panawé Kassang, Winga Foma, SefakoAbla Akakpo, Julienne Noude Teclessou, Kelly Tcheumagam, Essobiziou Amana, Kwame Doh, Gloria Nouhoumon, Tchin Darre, Koussake Kombate, Palokinam Pitché, Bayaki Saka

{"title":"Multiple Squamous Cell Carcinoma in a Patient Using Skin Bleaching Products in Togo.","authors":"Abas Mouhari-Toure, Panawé Kassang, Winga Foma, SefakoAbla Akakpo, Julienne Noude Teclessou, Kelly Tcheumagam, Essobiziou Amana, Kwame Doh, Gloria Nouhoumon, Tchin Darre, Koussake Kombate, Palokinam Pitché, Bayaki Saka","doi":"10.1155/2023/8002896","DOIUrl":"https://doi.org/10.1155/2023/8002896","url":null,"abstract":"Background: The cosmetic use of skin bleaching products is common among women in sub-Saharan Africa despite numerous reported cutaneous and systemic complications. We report the first case of squamous cell carcinoma in a woman using skin bleaching products in Togo. Case Report. A 65-year-old woman with a 30-year history of skin bleaching products use consulted in dermatology for a tumor of the neck that had been evolving for 2 years. There was no personal or family history of cancer. The patient was obese (BMI = 38.3 kg/m2) and had high blood pressure. Clinical examination noted multiple ulcerative and cauliflower tumors of the neck. The presence of stretch marks, skin atrophy, and ochronosis was noted in the examination of the rest of skin. There were no lymph nodes. HIV serology was negative. Histology of a tumor biopsy concluded to an invasive skin squamous cell carcinoma. The cervical, thoracic, abdominal, and pelvic TDM revealed pulmonary metastases. The patient underwent complete surgical removal of the right latero-cervical tumor. The left latero-cervical tumors were not removed because they infiltrated the large vessels. Chemotherapy before surgery was prescribed but not honored for financial reasons. The patient died 2 months after her first consultation in respiratory distress.Conclusion: Squamous cell carcinoma is one of the complications of skin bleaching in sub-Saharan Africa. It is necessary to intensify awareness campaigns on the complications of this practice, in order to reduce their incidence, in our context where this practice is very frequent.","PeriodicalId":9630,"journal":{"name":"Case Reports in Dermatological Medicine","volume":"2023 ","pages":"8002896"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9848785/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10586373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Sebaceous Carcinoma of the Penis: A Rare, Dangerous Clinical Entity and the Importance of Immunohistochemistry in Diagnosis. 阴茎皮脂腺癌:一种罕见、危险的临床实体及免疫组织化学在诊断中的重要性。

Case Reports in Dermatological Medicine Pub Date : 2023-01-01 DOI: 10.1155/2023/6944296

Vikram Sahni, David S Cassarino

引用次数: 1