Case Reports in Dermatological Medicine最新文献

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Clinical Diagnosis and Treatment of Scurvy in a Young Adult With Poor Dietary Habits: A Case Report and Literature Review. 一名饮食习惯不良的年轻成年人坏血病的临床诊断和治疗:病例报告和文献综述。
Case Reports in Dermatological Medicine Pub Date : 2024-10-25 eCollection Date: 2024-01-01 DOI: 10.1155/2024/2779253
Lara Saeid, Moatasem Hussein Al-Janabi, Fouz Hassan
{"title":"Clinical Diagnosis and Treatment of Scurvy in a Young Adult With Poor Dietary Habits: A Case Report and Literature Review.","authors":"Lara Saeid, Moatasem Hussein Al-Janabi, Fouz Hassan","doi":"10.1155/2024/2779253","DOIUrl":"10.1155/2024/2779253","url":null,"abstract":"<p><p>Scurvy, once prevalent among sailors, is now rare due to improved access to fresh fruits and vegetables yet persists in individuals with poor dietary habits. We report a case of a 35-year-old male presenting with month-long, nonpainful, nonitchy lower extremity lesions. A dermatological examination revealed follicular hyperkeratosis, perifollicular bleeding, corkscrew hairs, bleeding gums, and hemorrhagic purpura. Despite unavailable plasma vitamin C testing, scurvy was diagnosed based on clinical features and dietary history. Treatment with vitamin C resulted in significant improvement within 10 days. Inadequate intake of fruits and vegetables causes vitamin C deficiency, impairing collagen synthesis and leading to typical scurvy symptoms. This case underscores the importance of considering scurvy in patients with compatible symptoms, focusing on clinical diagnosis and treatment response when testing is unavailable. Management includes vitamin C supplementation and dietary changes, emphasizing healthcare providers' role in promoting sufficient fruit and vegetable consumptions to prevent nutritional deficiencies.</p>","PeriodicalId":9630,"journal":{"name":"Case Reports in Dermatological Medicine","volume":"2024 ","pages":"2779253"},"PeriodicalIF":0.0,"publicationDate":"2024-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11530288/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142567398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effective Technique Using Combined CO2 Laser and Pulsed Dye Laser for Facial Angiofibromas Management in Tuberous Sclerosis. 使用二氧化碳激光和脉冲染料激光联合疗法治疗结节性硬化症面部血管纤维瘤的有效技术
Case Reports in Dermatological Medicine Pub Date : 2024-09-16 eCollection Date: 2024-01-01 DOI: 10.1155/2024/9775613
Giuseppe Lodi, Giovanni Cannarozzo, Irene Fusco, Tiziano Zingoni, Elena Campione, Mario Sannino
{"title":"Effective Technique Using Combined CO<sub>2</sub> Laser and Pulsed Dye Laser for Facial Angiofibromas Management in Tuberous Sclerosis.","authors":"Giuseppe Lodi, Giovanni Cannarozzo, Irene Fusco, Tiziano Zingoni, Elena Campione, Mario Sannino","doi":"10.1155/2024/9775613","DOIUrl":"10.1155/2024/9775613","url":null,"abstract":"<p><strong>Background: </strong>Facial angiofibromas (FAs) are a dermatological characteristic which are typically linked to tuberous sclerosis (TS).</p><p><strong>Aim: </strong>We discuss our experience, highlighting a rare occurrence of multiple FAs in a young patient, successfully treated with ablative CO<sub>2</sub> laser combined with PDL therapy.</p><p><strong>Methods: </strong>A 23-year-old male patient affected by TS who presents multiple erythematous and colored papules/nodules located on the face, mainly concentrated around nose, perinasal area, cheeks, and chin area, was treated with a combination of ablative CO<sub>2</sub> laser and a pulsed dye laser. The patient underwent 3 sessions of combined treatment with CO<sub>2</sub> and pulsed dye laser. The intralesional dye laser treatment was administered immediately after the CO<sub>2</sub> laser session. The time interval between the combined laser treatments was approximately two months.</p><p><strong>Results: </strong>After 4 months from the last laser treatment session, most of the facial erythematous and protruding lesions had improved. Following these procedures, the patient did not experience complications or severe adverse reaction.</p><p><strong>Conclusion: </strong>The combined use of the CO<sub>2</sub> and dye laser has been proved to be a safe and effective treatment for multiple FAs in the young patient affected by tuberous sclerosis.</p>","PeriodicalId":9630,"journal":{"name":"Case Reports in Dermatological Medicine","volume":"2024 ","pages":"9775613"},"PeriodicalIF":0.0,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11419839/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142307166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Case of Fish Sausage Anaphylaxis Induced by Epicutaneous Sensitization to Carmine Contained in Eyeshadows: The Effect of Chelation on Carmine Allergy. 眼影中含有的胭脂红经皮致敏诱发鱼香肠过敏性休克病例:螯合对胭脂红过敏的影响。
Case Reports in Dermatological Medicine Pub Date : 2024-09-11 eCollection Date: 2024-01-01 DOI: 10.1155/2024/1057957
Maiko Yamaura, Yuriko Iwahashi, Eri Hashimoto, Jun Miura, Yuri Murayama, Sachiko Koshikawa, Naoko Inomata
{"title":"A Case of Fish Sausage Anaphylaxis Induced by Epicutaneous Sensitization to Carmine Contained in Eyeshadows: The Effect of Chelation on Carmine Allergy.","authors":"Maiko Yamaura, Yuriko Iwahashi, Eri Hashimoto, Jun Miura, Yuri Murayama, Sachiko Koshikawa, Naoko Inomata","doi":"10.1155/2024/1057957","DOIUrl":"https://doi.org/10.1155/2024/1057957","url":null,"abstract":"<p><p>Carmine is an aluminium and/or calcium-chelated complex form of carminic acid (CA), which is derived from the <i>Dactylopius coccus</i> extract (cochineal), and is globally used as a red-colourant in foods and cosmetics. Although several allergens in carmine allergies, such as CC38K, have been reported, it remains unknown whether chelation affects the allergenicity of carmine. We report a case of Japanese fish sausage (<i>Gyoniku Sausage</i>) anaphylaxis induced by epicutaneous sensitization to carmine contained in eyeshadows. In addition, we report on the effect of chelation on carmine allergy. A 32-year-old woman had experienced itching, wheals, and swelling of her eyelids immediately after applying pink eyeshadows, which contained carmine, on several occasions for 3 years. Two months ago, she developed itching, wheals, and swelling on her whole body, especially her eyelids, and dyspnea immediately after ingesting fried pink fish sausages, which contained cochineal. In skin prick tests (SPTs) with all ingredients ingested in the two episodes of anaphylaxis, only fish sausage was positive. SPT was also positive for carmine. In IgE-immunoblotting using the eyeshadow and fish sausage, the patient serum IgE was bound to three protein bands at approximately 86, 114, and 130 kDa. In addition, IgE-immunoblotting using the carmine showed a broad band at 86-130 kDa, which were consistent with those using the eyeshadow and fish sausage, whereas there is no band using CA. Interestingly, the protein bands using the eyeshadow and carmine were diminished by preincubation in the presence of ethylenediaminetetraacetic acid (EDTA) as a chelating agent. The results indicated that the causative allergens of carmine contained in the eyeshadows could be dechelated by EDTA, reducing its allergenicity. In conclusion, carmine contained in cosmetics can cause epicutaneous sensitisation and consequently can induce food anaphylaxis. To prevent sensitisation in carmine allergy, the effect of chelation on allergenicity of carmine should be considered.</p>","PeriodicalId":9630,"journal":{"name":"Case Reports in Dermatological Medicine","volume":"2024 ","pages":"1057957"},"PeriodicalIF":0.0,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11410408/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142280607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Phloroglucinol-Induced Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome with Subsequent Fulminant Type 1 Diabetes (FT1D): A Rare Case and Literature Review. 嗜酸性粒细胞增多和全身症状(DRESS)药物反应综合征(Phloroglucinol-Induced Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome)并继发暴发性 1 型糖尿病(FT1D):罕见病例及文献综述。
Case Reports in Dermatological Medicine Pub Date : 2024-09-06 eCollection Date: 2024-01-01 DOI: 10.1155/2024/1018971
Chengbei Bao, Zequn Tong, Qiuyun Xu, Zhixun Xiao, Bo Cheng, Ting Gong, Chao Ji
{"title":"Phloroglucinol-Induced Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome with Subsequent Fulminant Type 1 Diabetes (FT1D): A Rare Case and Literature Review.","authors":"Chengbei Bao, Zequn Tong, Qiuyun Xu, Zhixun Xiao, Bo Cheng, Ting Gong, Chao Ji","doi":"10.1155/2024/1018971","DOIUrl":"https://doi.org/10.1155/2024/1018971","url":null,"abstract":"<p><p>This study reported a woman with drug reaction with eosinophilia and systemic symptom (DRESS) syndrome induced by phloroglucinol who developed fulminant type 1 diabetes as sequelae. The literature review emphasized the necessity of at least seven months of follow-up for better management of DRESS syndrome.</p>","PeriodicalId":9630,"journal":{"name":"Case Reports in Dermatological Medicine","volume":"2024 ","pages":"1018971"},"PeriodicalIF":0.0,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11398957/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142280608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Therapeutic Response of Alopecia Areata-Associated Nail Changes to Baricitinib. 白发症相关指甲变化对巴利替尼的治疗反应
Case Reports in Dermatological Medicine Pub Date : 2024-08-31 eCollection Date: 2024-01-01 DOI: 10.1155/2024/8879884
Ashley Wittmer, Katherine De Jong, Lauren Bolish, Lindsey Finklea
{"title":"Therapeutic Response of Alopecia Areata-Associated Nail Changes to Baricitinib.","authors":"Ashley Wittmer, Katherine De Jong, Lauren Bolish, Lindsey Finklea","doi":"10.1155/2024/8879884","DOIUrl":"10.1155/2024/8879884","url":null,"abstract":"<p><p>Nail changes are seen in some individuals with alopecia areata, with the most common variants including pitting and trachyonychia. The nail findings are presumed to be due to the same lymphocytic infiltration seen in hair bulbs in individuals with AA. Baricitinib is an immunomodulatory drug that acts as a selective and reversible inhibitor of JAK proteins and is indicated for adult patients with moderate to severe rheumatoid arthritis who have not responded to other disease-modifying antirheumatic drugs. The FDA has also approved baricitinib to treat patients hospitalized with COVID-19 and severe alopecia areata. In this report, we present a case of a patient with persistent AA-associated nail changes who has been successfully treated with baricitinib. The patient has been suffering from alopecia for several years. She presented with periungual inflammation in conjunction with persistent fingernail ridges and pitting of her right fourth digit. The nail dystrophy persisted despite treatment with tacrolimus ointment, clobetasol ointment, or oral fluconazole. Patient was started on a trial of baricitinib for alopecia areata, which was the suspected cause of the nail changes. After 4 months of treatment with baricitinib, the patient's nail showed mild improvement of nail dystrophy with some clubbing and pitting still present. Within 11 months of treatment, her nail was normalized in appearance and texture. There are no established guidelines to treat AA-associated nail changes. Our patient's AA-associated nail changes were normalized after 11 months of treatment with baricitinib. Further research is needed to determine which alopecia areata patients may benefit from treatment with baricitinib and when treatment should be initiated. Baricitinib may be an effective treatment option for AA-associated nail changes in some patients.</p>","PeriodicalId":9630,"journal":{"name":"Case Reports in Dermatological Medicine","volume":"2024 ","pages":"8879884"},"PeriodicalIF":0.0,"publicationDate":"2024-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11380711/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142153193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adult-Onset Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis Syndrome on the Basis of Selective IgA Deficiency. 基于选择性 IgA 缺乏症的成人周期性发热、口腔炎、咽炎和宫颈腺炎综合征
Case Reports in Dermatological Medicine Pub Date : 2024-07-31 eCollection Date: 2024-01-01 DOI: 10.1155/2024/9845501
Seda Altiner, Alper Ekinci
{"title":"Adult-Onset Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis Syndrome on the Basis of Selective IgA Deficiency.","authors":"Seda Altiner, Alper Ekinci","doi":"10.1155/2024/9845501","DOIUrl":"10.1155/2024/9845501","url":null,"abstract":"<p><p>Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome (PFAPA) is an autoinflammatory disease that is thought to occur with the contribution of genetic and environmental factors, but its etiology has not been clearly elucidated. It is characterized by recurrent attacks with fever, pharyngitis, oral aphthous lesions, and cervical lymphadenopathy, and an increase in the level of serum acute phase reactants is observed during the attacks. Although PFAPA usually begins in childhood, adult-onset cases are also reported in the literature. In the pathogenesis of PFAPA, an increase in the expression of various inflammatory cytokines, especially interleukin-1<i>β</i> (IL-1<i>β</i>), is observed as a result of the increase in inflammasome activity. Selective IgA deficiency (SIgAD) is the most prevalent primary immunodeficiency. Although most SIgAD cases remain asymptomatic and remain undiagnosed, it is known that the risk of mucosal infection is generally increased in SIgAD cases. In addition, the frequency of autoinflammatory diseases is increased in SIgAD cases compared with the general population. We aim to present a case of adult-onset PFAPA and SIgAD coexistence.</p>","PeriodicalId":9630,"journal":{"name":"Case Reports in Dermatological Medicine","volume":"2024 ","pages":"9845501"},"PeriodicalIF":0.0,"publicationDate":"2024-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11306723/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141906046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Successful Use of Dupilumab in the Treatment of Acquired Perforating Dermatosis Associated with Atopic Dermatitis. 成功使用杜匹单抗治疗特应性皮炎相关的获得性穿孔性皮肤病。
Case Reports in Dermatological Medicine Pub Date : 2024-06-19 eCollection Date: 2024-01-01 DOI: 10.1155/2024/6265608
Niccolò Gori, Eleonora De Luca, Andrea Chiricozzi, Stefania Sfregola, Alessandro Di Stefani, Ketty Peris
{"title":"Successful Use of Dupilumab in the Treatment of Acquired Perforating Dermatosis Associated with Atopic Dermatitis.","authors":"Niccolò Gori, Eleonora De Luca, Andrea Chiricozzi, Stefania Sfregola, Alessandro Di Stefani, Ketty Peris","doi":"10.1155/2024/6265608","DOIUrl":"10.1155/2024/6265608","url":null,"abstract":"<p><p>Acquired reactive perforating collagenosis is a rare cutaneous disorder characterised by the extrusion of abnormal connective tissue trough epidermidis and/or follicular units. Reactive perforating collagenosis is often associated with systemic diseases in which pruritus is a common symptom (e.g., diabetes and chronic kidney disease). Less commonly, it has been associated with chronic inflammatory dermatoses, including atopic dermatitis, as in this case. In this report, we describe the exceptional case of a 35-year-old man affected by acquired reactive perforating collagenosis associated with atopic dermatitis who was resistant to conventional topical and systemic treatment and experienced complete resolution of clinical signs and symptoms after 12 weeks of treatment with dupilumab. In our patient, the severe pruritus induced by atopic dermatitis likely contributed to the development of acquired perforating collagenosis lesions, which are thought to be a reactive response to chronic scratching and repetitive injury to the skin. Chronic pruritus in atopic dermatitis is known to be driven by type 2 cytokines, including IL-4 and IL-13, and dupilumab, a monoclonal antibody inhibiting IL-4 and IL-13 signalling, has been shown to be effective in the treatment of moderate to severe atopic dermatitis as well as other type 2-driven pruritic dermatological conditions. This case supports the potential use of dupilumab for the treatment of reactive perforating dermatosis.</p>","PeriodicalId":9630,"journal":{"name":"Case Reports in Dermatological Medicine","volume":"2024 ","pages":"6265608"},"PeriodicalIF":0.0,"publicationDate":"2024-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11208807/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141466412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Successful Treatment of Refractory Generalized Granuloma Annulare with Upadacitinib. 乌达帕替尼成功治疗难治性全身性环状肉芽肿
Case Reports in Dermatological Medicine Pub Date : 2024-06-05 eCollection Date: 2024-01-01 DOI: 10.1155/2024/8859178
Alexis Coican, Abigail Meckley, Nathan Sagasser, Melinda Greenfield, Eingun James Song, Jessica El-Bahri
{"title":"Successful Treatment of Refractory Generalized Granuloma Annulare with Upadacitinib.","authors":"Alexis Coican, Abigail Meckley, Nathan Sagasser, Melinda Greenfield, Eingun James Song, Jessica El-Bahri","doi":"10.1155/2024/8859178","DOIUrl":"10.1155/2024/8859178","url":null,"abstract":"<p><p>Granuloma annulare is a poorly understood dermatosis that, when generalized, can occur in up to 15 percent of patients. In these cases, treatment is frustrating and experimental. We report a case of a 60-year-old woman and a 41-year-old woman who demonstrated resolution of recalcitrant, generalized granuloma annulare (GA) following oral treatment with upadacitinib. After showing little to no response to other various treatments, such as steroids, antibiotic regimens, and systemic therapies, each patient was started on 15 mg of daily upadacitinib. At 2 months, one patient had complete clearance of all lesions while the other patient experienced noticeable improvement. Within 4 months, the other patient reached total resolution of her lesions. These cases provide evidence of a therapeutic option that may shorten disease duration and provide relief from cutaneous disease.</p>","PeriodicalId":9630,"journal":{"name":"Case Reports in Dermatological Medicine","volume":"2024 ","pages":"8859178"},"PeriodicalIF":0.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11208790/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141466411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reactive Angioendotheliomatosis in Association with Ulcerative Colitis. 与溃疡性结肠炎有关的反应性血管内皮瘤病
Case Reports in Dermatological Medicine Pub Date : 2024-05-29 eCollection Date: 2024-01-01 DOI: 10.1155/2024/6505274
R Afiouni, G Abadjian, F Stephan
{"title":"Reactive Angioendotheliomatosis in Association with Ulcerative Colitis.","authors":"R Afiouni, G Abadjian, F Stephan","doi":"10.1155/2024/6505274","DOIUrl":"10.1155/2024/6505274","url":null,"abstract":"<p><p>Reactive angioendotheliomatosis (RAE) is a rare benign skin condition characterized histologically by the proliferation of dermal vessels and endothelial cells that occurs secondary to an underlying disease such as infections or lymphoproliferative disorders. To our knowledge, no previous cases of RAE associated with ulcerative colitis (UC) were reported in the literature. Therefore, we report the case of a 46-year-old man with a history of UC presenting with RAE confirmed on histopathology and immunostaining.</p>","PeriodicalId":9630,"journal":{"name":"Case Reports in Dermatological Medicine","volume":"2024 ","pages":"6505274"},"PeriodicalIF":0.0,"publicationDate":"2024-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11152761/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141261240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Granuloma after the Injection of Poly-D,L-Lactic Acid (PDLLA) Treated with Triamcinolone 注射聚-D,L-乳酸 (PDLLA) 并用曲安奈德治疗后出现的肉芽肿
Case Reports in Dermatological Medicine Pub Date : 2024-04-25 DOI: 10.1155/2024/6544506
Kateryn Michelle Perez Willis, Rosario Ramirez Galvez
{"title":"Granuloma after the Injection of Poly-D,L-Lactic Acid (PDLLA) Treated with Triamcinolone","authors":"Kateryn Michelle Perez Willis, Rosario Ramirez Galvez","doi":"10.1155/2024/6544506","DOIUrl":"https://doi.org/10.1155/2024/6544506","url":null,"abstract":"Biostimulators are the latest trends in cosmetic procedures, substances such as PDLLA are used to induce collagen synthesis by a subclinical inflammatory reaction. We are describing a granuloma-like reaction case presentation 4 months after the application of PDLLA and its complete resolution with injections of triamcinolone. A 45-year-old female with any past medical history of allergies or immune diseases was injected with PDLLA on the mandibular border and cheek area to correct skin laxity. Four months after the application, the patient reported facial edema and granuloma-like reactions according to clinical examination on all the application areas. The ultrasound reports showed the presence of multiple nodules in the injection areas; therefore, we decided to apply triamcinolone to the granulomatous reaction areas 2 times a month and Prednisone 20 mg daily for 3 days followed by 10 mg for 2 days. After 4 applications, the adverse reaction was completely solved. Biostimulators are biocompatible and resorbable substances; however, nodules and/or granulomas have been reported as rare adverse events. Intralesional and oral steroids can allow us to treat this kind of adverse events.","PeriodicalId":9630,"journal":{"name":"Case Reports in Dermatological Medicine","volume":"10 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140658622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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