Case Reports in Medicine最新文献

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Endovascular Management of a Deep Femoral Artery Perforating Branch Pseudoaneurysm after Total Hip Arthroplasty: A Case Study. 全髋关节置换术后股深动脉穿支假性动脉瘤的血管内治疗:一例病例研究。
IF 0.8
Case Reports in Medicine Pub Date : 2022-11-23 eCollection Date: 2022-01-01 DOI: 10.1155/2022/5925839
Sami Nabhani, Eric Cheysson, Pamela Sabbah, Georges Baaklini
{"title":"Endovascular Management of a Deep Femoral Artery Perforating Branch Pseudoaneurysm after Total Hip Arthroplasty: A Case Study.","authors":"Sami Nabhani,&nbsp;Eric Cheysson,&nbsp;Pamela Sabbah,&nbsp;Georges Baaklini","doi":"10.1155/2022/5925839","DOIUrl":"https://doi.org/10.1155/2022/5925839","url":null,"abstract":"<p><p>Pseudoaneurysm of the profundal femoris artery (PFA) following total hip arthroplasty (THA) is a rare and unusual complication. Awareness of this complication and a high level of suspicion allow early diagnosis and treatment, thereby reducing the morbidity of this condition. We present a case of a pseudoaneurysm of a perforating branch of the PFA after revision THA which was treated successfully by selective coil embolization.</p>","PeriodicalId":9627,"journal":{"name":"Case Reports in Medicine","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2022-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712022/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35209449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cutaneous Larvae Migrans Treated with a Single Dose of Ivermectin. 单剂量伊维菌素治疗皮肤幼虫迁移。
IF 0.8
Case Reports in Medicine Pub Date : 2022-11-16 eCollection Date: 2022-01-01 DOI: 10.1155/2022/8215335
Iris S Harrison, Kiran Lukose, Bhagwan Dass, Nila S Radhakrishnan
{"title":"Cutaneous Larvae Migrans Treated with a Single Dose of Ivermectin.","authors":"Iris S Harrison,&nbsp;Kiran Lukose,&nbsp;Bhagwan Dass,&nbsp;Nila S Radhakrishnan","doi":"10.1155/2022/8215335","DOIUrl":"https://doi.org/10.1155/2022/8215335","url":null,"abstract":"<p><p>Hookworm-related cutaneous larva migrans (HrCLM) is a clinical diagnosis based on a history of exposure to contaminated soil and is associated with a characteristic red serpiginous lesion that migrates within the <i>epidermis</i>. Our patient presented with a red, tortuous migratory rash with localized pruritus on the left plantar foot of 1-month duration. He lacked recent travel history outside the southeastern United States. Upon admission, he presented with peripheral blood eosinophilia, an uncommon feature of HrCLM. A single dose of ivermectin was sufficient for treatment, and symptoms resolved within 3 days. This case highlights the increased incidence of domestically acquired hookworm infections, explores this epidemiological shift, and emphasizes relevant differential diagnoses.</p>","PeriodicalId":9627,"journal":{"name":"Case Reports in Medicine","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2022-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9683989/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40707966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Triple Jeopardy: Rapidly Progressive Glomerulonephritis Induced by Triple Seropositive Disease-A Rare Case. 三重危险:由三重血清阳性疾病引起的快速进展性肾小球肾炎——罕见病例。
IF 0.8
Case Reports in Medicine Pub Date : 2022-11-14 eCollection Date: 2022-01-01 DOI: 10.1155/2022/2032525
Apurva Vedire, Gautham Upadrasta, Ndausung Udongwo, Faseeha Rehman, Mohammad A Hossain
{"title":"Triple Jeopardy: Rapidly Progressive Glomerulonephritis Induced by Triple Seropositive Disease-A Rare Case.","authors":"Apurva Vedire,&nbsp;Gautham Upadrasta,&nbsp;Ndausung Udongwo,&nbsp;Faseeha Rehman,&nbsp;Mohammad A Hossain","doi":"10.1155/2022/2032525","DOIUrl":"https://doi.org/10.1155/2022/2032525","url":null,"abstract":"<p><p>The double-positive disease is the co-occurrence of antiglomerular basement membrane (anti-GBM) disease and antineutrophil cytoplasmic antibodies (ANCAs) and is an uncommon cause of renal failure. Our case of triple-positive disease is an even rarer cause of isolated renal failure, as it includes anti-GBM, antimyeloperoxidase (MPO), and antiproteinase 3 (PR3). We present a case of a 62-year-old Caucasian male with a history of multiple comorbidities, who presented to the emergency department (ED) with worsening dyspnea on exertion that started about one month prior to admission. He was found to be in renal failure secondary to triple-positive disease. We believe that the likely mechanism of our patient's triple-positive disease was a drug-induced ANCA vasculitis overlapping with Goodpasture's syndrome. We believe our case to be a valuable addition to the literature as it is a rare overlap syndrome without a previously established disease course or etiology.</p>","PeriodicalId":9627,"journal":{"name":"Case Reports in Medicine","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2022-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678450/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40507995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Single Coronary Artery from Right Sinus of Valsalva: A Single Center Experience of Seven Cases. 瓦尔萨尔瓦右窦单根冠状动脉:7例单中心经验。
IF 0.8
Case Reports in Medicine Pub Date : 2022-10-20 eCollection Date: 2022-01-01 DOI: 10.1155/2022/1513474
Kanhai Lalani, M Sudhakar Rao, Padmakumar Ramachandran, A J Ashwal, Abdul U K Razak, Tom Devasia, Ganesh Paramasivam, Pankti Parikh
{"title":"Single Coronary Artery from Right Sinus of Valsalva: A Single Center Experience of Seven Cases.","authors":"Kanhai Lalani,&nbsp;M Sudhakar Rao,&nbsp;Padmakumar Ramachandran,&nbsp;A J Ashwal,&nbsp;Abdul U K Razak,&nbsp;Tom Devasia,&nbsp;Ganesh Paramasivam,&nbsp;Pankti Parikh","doi":"10.1155/2022/1513474","DOIUrl":"https://doi.org/10.1155/2022/1513474","url":null,"abstract":"<p><strong>Background: </strong>Single coronary artery (SCA) is a rare anomaly with a prevalence of 0.024-0.066%. Some anomalies are merely benign anatomical variants, whereas some can result in myocardial ischemia or life-threatening arrhythmia. <i>Case Presentation</i>. We described seven cases in which all three major coronaries emerged from the right sinus of Valsalva via a single ostium and supplied the vast majority of the myocardium. A smaller branch arising from the left sinus supplied a modest quantity of myocardium in some of those few cases. These SCA variations do not exactly fit into any existing classification. It is unclear whether we need to modify previous classification systems or newer classification systems.</p><p><strong>Conclusions: </strong>SCA is divided based on its anomalous course and is usually a benign condition but it may present with cardiovascular complications. Clinicians should be aware of this entity along with the role of CT angiogram in its diagnosis and management.</p>","PeriodicalId":9627,"journal":{"name":"Case Reports in Medicine","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2022-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613390/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40655870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Ischemic Stroke Secondary to a Stab Wound to the Neck in a Young Adult. 年轻成人颈部刺伤继发缺血性中风。
IF 0.8
Case Reports in Medicine Pub Date : 2022-10-18 eCollection Date: 2022-01-01 DOI: 10.1155/2022/9365947
Mateo Zuluaga-Gómez, Daniela Giraldo-Campillo, Daniel González-Arroyave, Carlos M Ardila
{"title":"Ischemic Stroke Secondary to a Stab Wound to the Neck in a Young Adult.","authors":"Mateo Zuluaga-Gómez,&nbsp;Daniela Giraldo-Campillo,&nbsp;Daniel González-Arroyave,&nbsp;Carlos M Ardila","doi":"10.1155/2022/9365947","DOIUrl":"https://doi.org/10.1155/2022/9365947","url":null,"abstract":"<p><p>Vertebral artery dissection is a common cause of stroke in young adults without predisposing risk factors for cerebrovascular disease. We describe the case of a 28-year-old patient who presented with an ischemic stroke secondary to a stab wound to the neck that affected the vertebral artery. A physical examination revealed neurological deterioration (Glasgow 8/15), a sutured neck wound, no palpable hematoma, no thrills, and no active bleeding. A computed tomography angiography revealed a left vertebral artery arteriovenous fistula with a component of a pseudoaneurysm, for which a neurointerventional consultation was carried out. Due to neurological compromise, the airway was secured, and because the case involved a posterior fossa infarction with compression of the fourth ventricle and obstructive secondary hydrocephalus, an external ventricular shunt was inserted by neurosurgery. A fistula occlusion was performed with five Axium coils and a vial of Squid 12; the vertebral artery was catheterized, and a craniotomy was performed to manage hydrocephalus with a 12-mm H<sub>2</sub>O collecting system. The patient was discharged on the tenth day after admission with sequelae of left hemiparesis (predominantly brachial) and no other deficits. There was no hemorrhagic transformation on the control computed tomography scans and no further complications.</p>","PeriodicalId":9627,"journal":{"name":"Case Reports in Medicine","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2022-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596234/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40651845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Late Systemic Lupus Erythematosus-Associated Insulin Resistance Syndrome: A Rare Cause of De Novo Diabetes Mellitus. 晚期系统性红斑狼疮伴胰岛素抵抗综合征:新生糖尿病的罕见病因。
IF 0.8
Case Reports in Medicine Pub Date : 2022-10-14 eCollection Date: 2022-01-01 DOI: 10.1155/2022/4655804
José C Alvarez-Payares, Daniel Ribero, Luis Rodríguez, Carlos E Builes, Carolina Prieto, Clara Arango, Juan G Gamboa, Cristian Alvarez-Payares
{"title":"Late Systemic Lupus Erythematosus-Associated Insulin Resistance Syndrome: A Rare Cause of De Novo Diabetes Mellitus.","authors":"José C Alvarez-Payares,&nbsp;Daniel Ribero,&nbsp;Luis Rodríguez,&nbsp;Carlos E Builes,&nbsp;Carolina Prieto,&nbsp;Clara Arango,&nbsp;Juan G Gamboa,&nbsp;Cristian Alvarez-Payares","doi":"10.1155/2022/4655804","DOIUrl":"https://doi.org/10.1155/2022/4655804","url":null,"abstract":"<p><p>The association of type B insulin resistance syndrome (TBIRS) due to autoimmune diseases such as systemic lupus erythematosus (SLE) is uncommon. This is partly due to the lack of established criteria for the diagnosis of this resistance. However, some clinical aspects may suggest that the diagnosis does not necessarily have to be positive insulin receptor antibodies as such patients could respond to immunosuppressive treatment. <i>Methods</i>. We describe a case and have performed a literature review on PubMed/MEDLINE, EMBASE, and Google Scholar bibliographic databases to identify all case reports. All available studies from January 1975 through December 2020 were included. Data collected were tabulated, and outcomes were analyzed cumulatively. <i>Results</i>. Thirty-one cases of TBIRS associated with SLE have been described. These patients presented with catabolic symptoms and hyperglycemia in most cases, with an average time from the onset of symptoms of four months. In addition to that clinical characteristics related to SLE were variable, along with certain common characteristics such as acanthosis in 60% of patients. Almost all the patients had antibodies against insulin receptors. The insulin doses required by the patients ranged from 450 to 25,000 U daily. Remission was achieved in 80% of the patients with a two-year follow-up. Most patients associated with late-onset SLE, like our patient, achieved metabolic control after immunosuppressive treatment. <i>Conclusion</i>. High insulin resistance in patients with de novo diabetes mellitus (DM) without obesity should be considered as a possible clinical manifestation of an autoimmune disease such as SLE, with a good metabolic response to the immunosuppressive management established.</p>","PeriodicalId":9627,"journal":{"name":"Case Reports in Medicine","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2022-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586807/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40654048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Aortosternal Venous Compression: A Review of Two Cases. 胸主动脉静脉压迫2例分析。
IF 0.8
Case Reports in Medicine Pub Date : 2022-10-05 eCollection Date: 2022-01-01 DOI: 10.1155/2022/4591024
Victoria Giglio, Zain Badar, Yasovineeth Bhogadi, Brian Van Adel, Gordon Yip
{"title":"Aortosternal Venous Compression: A Review of Two Cases.","authors":"Victoria Giglio,&nbsp;Zain Badar,&nbsp;Yasovineeth Bhogadi,&nbsp;Brian Van Adel,&nbsp;Gordon Yip","doi":"10.1155/2022/4591024","DOIUrl":"https://doi.org/10.1155/2022/4591024","url":null,"abstract":"<p><p>Aortosternal venous compression (AVC) is a rare venous compression syndrome that involves brachiocephalic venous compression due to its positioning between the sternum and the aorta. One of the features of AVC involves compression of the left innominate vein with variability in luminal caliber on inspiration and expiration. Imaging modalities such as computed tomography (CT) examination can aid in initial diagnosis; however, venography can be utilized for confirmatory diagnosis due to its higher specificity during the inspiratory and expiratory phases. Through findings demonstrated during venography, we herein present two cases of confirmed AVC secondary to an aberrant right subclavian artery. Characteristic imaging features in the diagnosis of AVC and its etiology are discussed.</p>","PeriodicalId":9627,"journal":{"name":"Case Reports in Medicine","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2022-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556204/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33514866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hydroxychloroquine Therapy Led to the Diagnosis of Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency in an Elderly Patient with COVID-19 Involvement: A Case Report and Review of the Literature. 羟氯喹治疗导致1例老年COVID-19患者诊断为葡萄糖-6-磷酸脱氢酶(G6PD)缺乏:1例报告及文献复习
IF 0.8
Case Reports in Medicine Pub Date : 2022-10-03 eCollection Date: 2022-01-01 DOI: 10.1155/2022/4749424
Razieh Taghizadeh-Sarvestani, Hamid Reihani, Ali Ghanei-Shahmirzadi, Alireza Keshtkar, Parsa Yazdanpanahi
{"title":"Hydroxychloroquine Therapy Led to the Diagnosis of Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency in an Elderly Patient with COVID-19 Involvement: A Case Report and Review of the Literature.","authors":"Razieh Taghizadeh-Sarvestani,&nbsp;Hamid Reihani,&nbsp;Ali Ghanei-Shahmirzadi,&nbsp;Alireza Keshtkar,&nbsp;Parsa Yazdanpanahi","doi":"10.1155/2022/4749424","DOIUrl":"https://doi.org/10.1155/2022/4749424","url":null,"abstract":"<p><p>Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common RBC abnormality, affecting 400 million people globally. Neonatal jaundice, hemolytic anemia, icteric skin, dark urine, and fever are usually the primary signs of this condition, which is generally diagnosed between the ages of infancy and 16 years old. Therefore, its first manifestation in old age is an unexpected phenomenon. Here, we present the case of a 70-year-old man with no past medical history of G6PD deficiency that was admitted to our hospital due to COVID-19 infection and developed acute hemolytic anemia while receiving hydroxychloroquine (HCQ) medication for COVID-19-related pneumonia.</p>","PeriodicalId":9627,"journal":{"name":"Case Reports in Medicine","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2022-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550493/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33503426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Giant Partially Thrombosed Coronary Aneurysm in Multisystem Inflammatory Syndrome Associated with SARS-CoV-2 in Children. 儿童与SARS-CoV-2相关的多系统炎症综合征中的巨大部分血栓性冠状动脉瘤
IF 0.8
Case Reports in Medicine Pub Date : 2022-09-28 eCollection Date: 2022-01-01 DOI: 10.1155/2022/3785103
Karen Daniela Manchola Narváez, Natalia Del Pilar Delgado Ortíz, Iván José Ardila Gómez, Pilar Pérez López, Martín Fernando Rivera Ortíz
{"title":"Giant Partially Thrombosed Coronary Aneurysm in Multisystem Inflammatory Syndrome Associated with SARS-CoV-2 in Children.","authors":"Karen Daniela Manchola Narváez,&nbsp;Natalia Del Pilar Delgado Ortíz,&nbsp;Iván José Ardila Gómez,&nbsp;Pilar Pérez López,&nbsp;Martín Fernando Rivera Ortíz","doi":"10.1155/2022/3785103","DOIUrl":"https://doi.org/10.1155/2022/3785103","url":null,"abstract":"<p><p>Multisystem inflammatory syndrome in children (MIS-C) is a postinfectious condition which usually develops 4 to 6 weeks after SARS-CoV-2 infection in a genetically predisposed individual. Clinical features are heterogeneous and include fever, respiratory compromise, mucocutaneous involvement with conjunctival abnormalities and erythematous exanthem, abdominal pain, and diarrhea. Neurologic and cardiovascular symptoms can also develop, including coronary artery dilatation. Some cases involve 2 or more organs and require critical admission. Echocardiography is the mainstay of cardiac evaluation in the acute setting as well as on outpatient follow-up. We present the case of a 4-month-old female with no past medical or surgical history who presented with a prolonged febrile syndrome associated with severe respiratory illness, gastrointestinal symptoms, and mucocutaneous abnormalities. Diagnosis of MIS-C was established based on clinical findings, persistently elevated markers of systemic inflammation and positive SARS-CoV-2 molecular test and evidence of prior SARS-CoV-2 infection with SARS-CoV-2 IgG positive. Echocardiogram evidenced myopericarditis and coronary aneurysms and patient was deemed candidate for immunomodulatory therapy with intravenous immunoglobulin (IVIg), resulting in favorable clinical and paraclinical outcomes. Few cases of giant coronary aneurysms have been reported in children. There are no existing literature reports about coronary thrombosis or thrombus formation resulting from vascular aneurysmal dilations in this population. As such, the prognosis and natural history of coronary artery aneurysms in the setting of MIS-C remain largely unknown.</p>","PeriodicalId":9627,"journal":{"name":"Case Reports in Medicine","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2022-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534692/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33496307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Diffuse-Type Tenosynovial Giant Cell Tumour Involving Bone Masquerading as Langerhans Cell Histiocytosis. 弥漫性腱鞘巨细胞瘤累及骨,伪装为朗格汉斯细胞组织细胞增生症。
IF 0.8
Case Reports in Medicine Pub Date : 2022-09-15 eCollection Date: 2022-01-01 DOI: 10.1155/2022/1992541
Florence M F Cheung, Timothy Y C So, Tony H T Sung, Ying-Lee Lam
{"title":"Diffuse-Type Tenosynovial Giant Cell Tumour Involving Bone Masquerading as Langerhans Cell Histiocytosis.","authors":"Florence M F Cheung,&nbsp;Timothy Y C So,&nbsp;Tony H T Sung,&nbsp;Ying-Lee Lam","doi":"10.1155/2022/1992541","DOIUrl":"https://doi.org/10.1155/2022/1992541","url":null,"abstract":"<p><p>We presented a case of diffuse-type tenosynovial giant cell tumour (DTSGCT) of foot masquerading as Langerhans cell histiocytosis. Preliminary diagnosis by needle biopsy was difficult due to the major involvement of bones and the overshadowing effect of the accompanying Langerhans cells. The complete curettage specimen with relevant immunohistochemistry and molecular tests made the final diagnosis of DTSGCT possible. The biomolecular mechanism for the masquerading phenomenon was explained by CSF1 overexpression in the neoplastic cells attracting migration and proliferation of CSF1R-positive Langerhans cells.</p>","PeriodicalId":9627,"journal":{"name":"Case Reports in Medicine","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2022-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499769/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33497464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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