Case Reports in Pediatrics最新文献_第3页

Airway Management for Massive Anterior Mediastinal Tumor Resection in an Infant: A Strategy Involving Spontaneous Breathing-Preserving Endotracheal Intubation under Intravenous Anesthesia. 婴儿大规模前纵隔肿瘤切除术的气道管理：静脉麻醉下气管内插管保留自主呼吸的策略。

IF 0.9

Case Reports in Pediatrics Pub Date : 2024-05-27 eCollection Date: 2024-01-01 DOI: 10.1155/2024/1727612

Hiromi Matsuda, Ei Ito, Akiko Katsuike, Hirotsugu Okamoto

引用次数: 0

Brain Abscess due to Streptococcus intermedius after Spontaneous Esophageal Perforation in an Adolescent. 青少年自发性食管穿孔后中间链球菌引起的脑脓肿。

IF 0.9

Case Reports in Pediatrics Pub Date : 2024-05-09 eCollection Date: 2024-01-01 DOI: 10.1155/2024/5593403

Sandra Mabel Camacho-Gomez, Javier Monagas, Robert Adam Noel, Luis Castagnini

引用次数: 0

Two Extremely Preterm Infants Discharged with a Home High-Flow Nasal Cannula for Severe Bronchopulmonary Dysplasia. 两名早产儿因严重支气管肺发育不良而使用家用高流量鼻导管出院。

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Case Reports in Pediatrics Pub Date : 2024-05-06 eCollection Date: 2024-01-01 DOI: 10.1155/2024/3266928

Yuichi Kubo, Takuya Tokuhisa, Hiroshi Ohashi

{"title":"Two Extremely Preterm Infants Discharged with a Home High-Flow Nasal Cannula for Severe Bronchopulmonary Dysplasia.","authors":"Yuichi Kubo, Takuya Tokuhisa, Hiroshi Ohashi","doi":"10.1155/2024/3266928","DOIUrl":"10.1155/2024/3266928","url":null,"abstract":"Home high-flow nasal cannula (HFNC) use in the neonatal field has become prevalent as a noninvasive respiratory support, but its application in home care remains rare. We report two cases in which a home HFNC was effective in managing extremely low-birth-weight infants with severe bronchopulmonary dysplasia (BPD). Case 1 was a male infant born at 22 weeks' gestation weighing 435 g. Case 2 was a female infant born at 23 weeks' gestation weighing 450 g. Both patients had mothers with chronic placental abruption or chorioamnionitis. They transitioned from invasive mechanical ventilation to nasal CPAP (nCPAP) at 45 days (case 1) and 50 days (case 2) old. Subsequently, at 324 days (case 1) and 90 days (case 2) old, they transitioned to a HFNC, demonstrating stable oxygenation and ventilation, but faced difficulty in removal. Considering the drawbacks of prolonged hospitalization, the patients were discharged using a home HFNC at 404 days (case 1) and 391 days (case 2) old. For case 1, the HFNC was set at 4 L/min of room air and 2 L/min of oxygen, whereas for case 2, it was set at 5 L/min of room air and 1 L/min of oxygen. These settings maintained an SpO2 above 90% and a pCO2 below 60 mmHg. An HFNC offers advantages over nCPAP owing to its lower invasiveness and reduced discomfort for long-term use. However, reports on the use of a home HFNC for BPD are scarce. In recent years, while premature infant mortality has decreased worldwide, the incidence of BPD has risen, necessitating preparedness for prolonged ventilation in preterm infants. Home ventilators represent a strategy to prevent extended hospitalization, and based on our cases, home HFNC for BPD appears safe and effective, making it potentially useful for managing preterm infants requiring prolonged respiratory support in the future.","PeriodicalId":9623,"journal":{"name":"Case Reports in Pediatrics","volume":"2024 ","pages":"3266928"},"PeriodicalIF":0.9,"publicationDate":"2024-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11090667/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140916039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Orofacial Granulomatosis among Pediatric Patients Well Controlled by Corticosteroid Treatment: A Rare Case Series. 经皮质类固醇治疗后病情得到良好控制的儿童口腔肉芽肿病：罕见病例系列。

IF 0.9

Case Reports in Pediatrics Pub Date : 2024-04-29 eCollection Date: 2024-01-01 DOI: 10.1155/2024/5685686

Taku Kimura, Ken-Ichiro Sakata, Shunichiro Takezaki, Takuya Asaka, Shohei Oshima, Aya Yanagawa-Matsuda, Yoshimasa Kitagawa

{"title":"Orofacial Granulomatosis among Pediatric Patients Well Controlled by Corticosteroid Treatment: A Rare Case Series.","authors":"Taku Kimura, Ken-Ichiro Sakata, Shunichiro Takezaki, Takuya Asaka, Shohei Oshima, Aya Yanagawa-Matsuda, Yoshimasa Kitagawa","doi":"10.1155/2024/5685686","DOIUrl":"10.1155/2024/5685686","url":null,"abstract":"Orofacial granulomatosis (OFG) is a rare disease entity characterized by nonnecrotizing granulomatous inflammation in the oral and maxillofacial regions, typically characterized by recurrent or persistent edema, primarily in the lips and occasionally in the gingiva. OFG is often associated with Crohn's disease and sarcoidosis, and an accurate diagnosis requires systemic examination of patients. Pediatric patients possess unique oral conditions where dental plaque rapidly forms, especially during tooth replacement due to tooth crowding. Moreover, controlling oral hygiene can be challenging, rendering it difficult to distinguish plaque-induced gingivitis from nonplaque-induced gingivitis. We elucidate the reports of pediatric patients who developed OFG in the lips and/or gingiva alone, which was well controlled through corticosteroid treatment. The patients demonstrated recurrent lips and/or gingival swelling with redness, which failed to improve despite oral health care and treatment with antibiotics and/or corticosteroid ointment. Incision biopsy was performed, which demonstrated granulomatous inflammation. Further systemic examination ruled out Crohn's disease and sarcoidosis and confirmed OFG diagnosis. Corticosteroid treatment orally or through gargling was administered to the patients, which provided improvement of symptoms after 1 month. As OFG may be associated with intractable diseases, monitoring the patient regularly is crucial. Pediatric patients with OFG require a collaborative approach with pediatricians and pediatric dentists to manage their oral and overall health.","PeriodicalId":9623,"journal":{"name":"Case Reports in Pediatrics","volume":"2024 ","pages":"5685686"},"PeriodicalIF":0.9,"publicationDate":"2024-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11073851/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140851596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cytokine Storm Syndrome Responsive to IL-1 Inhibition in Trisomy 21. 细胞因子风暴综合征对 21 三体综合征 IL-1 抑制的反应。

IF 0.7

Case Reports in Pediatrics Pub Date : 2024-03-28 eCollection Date: 2024-01-01 DOI: 10.1155/2024/9946401

Aimee Magnarelli, Julia Shalen, Maria J Gutierrez

{"title":"Cytokine Storm Syndrome Responsive to IL-1 Inhibition in Trisomy 21.","authors":"Aimee Magnarelli, Julia Shalen, Maria J Gutierrez","doi":"10.1155/2024/9946401","DOIUrl":"10.1155/2024/9946401","url":null,"abstract":"Background: Cytokine storm syndromes (CSS) are life-threatening systemic inflammatory disorders caused by immune system dysregulation. They can lead to organ failure and are triggered by various factors, including infections, malignancy, inborn errors of immunity, and autoimmune conditions. Trisomy 21 (TS21), also known as Down syndrome, is a genetic disorder associated with immune dysfunction, increased infection susceptibility, and inflammation. While TS21 has been linked to infectious-triggered hyperinflammation, its role as a primary cause of CSS has not been confirmed. Case Presentation. We present a case of a 16-year-old male with TS21 with fever, rash, joint pain, and abdominal symptoms. Extensive investigations ruled out infections, autoimmune conditions, malignancies, and inborn errors of immunity as triggers for a CSS. The patient's symptoms improved with treatment using IL-1 inhibition and corticosteroids.Conclusions: This case reinforces that TS21 is an immune dysregulation disorder and highlights the importance of considering CSS in TS21 patients, even when triggers are unclear. The positive response to IL-1 inhibition in this patient suggests that dysregulation of the IL-1 superfamily and the NLRP3 inflammasome may contribute to CSS in TS21. This finding raises the possibility of using IL-1 inhibition as a treatment approach for CSS in TS21 patients.","PeriodicalId":9623,"journal":{"name":"Case Reports in Pediatrics","volume":"2024 ","pages":"9946401"},"PeriodicalIF":0.7,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10994700/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140848044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Too Much Salt to My Taste: An Entity to Think about in Neonatal Hypernatremia: A Case Report and Review of the Literature. 对我的口味来说，盐太多了：新生儿高钠血症的一个思考实体：病例报告和文献综述。

IF 0.9

Case Reports in Pediatrics Pub Date : 2024-03-08 eCollection Date: 2024-01-01 DOI: 10.1155/2024/8838362

Marwa El Masri, Lidiya Samotiy-Hanna, Ramy Ghabril, Yolla Nassif, Dany Al Hamod

引用次数: 0

Digital Ischemia in an Extreme Preterm Infant Treated with Nitroglycerin Patch. 使用硝酸甘油贴片治疗极早产儿的数字缺血。

IF 0.9

Case Reports in Pediatrics Pub Date : 2024-02-28 eCollection Date: 2024-01-01 DOI: 10.1155/2024/2255756

Mansour Al Qurashi, Abdulaziz Al-Khotani, Farzeen Mohtisham, Eman AlRaddadi, Heba AlShaikh, Alqassem Y Hakami, Syed Sameer Aga

引用次数: 0

From Rarity to Recognition: Infantile Botulism and the Broad Spectrum of Differential Diagnoses. 从罕见到公认：婴儿肉毒中毒与广泛的鉴别诊断。

IF 0.9

Case Reports in Pediatrics Pub Date : 2024-02-26 eCollection Date: 2024-01-01 DOI: 10.1155/2024/4647591

Matthew C Authement, Brandon M Jones, Robert J Kahoud, Elizabeth H Ristagno

引用次数: 0

Unmasking the Hidden Culprit: A Coma Mimicry in a Child Bitten by Cobra 揭开隐藏的罪魁祸首：被眼镜蛇咬伤儿童的昏迷模仿症

IF 0.9

Case Reports in Pediatrics Pub Date : 2024-01-09 DOI: 10.1155/2024/6630842

Aphirak Mekmangkonthong, Khanittha Khusiwilai, Sudathip Paticheep, Duangtip Tiacharoen

引用次数: 0

Successful Termination of Insulin Therapy in Transient Neonatal Diabetes Mellitus. 成功终止一过性新生儿糖尿病的胰岛素治疗。

IF 0.9

Case Reports in Pediatrics Pub Date : 2023-12-11 eCollection Date: 2023-01-01 DOI: 10.1155/2023/6667330

Risa Sakai, Nobuyuki Kikuchi, Daisuke Nishi, Haruko Horiguchi

{"title":"Successful Termination of Insulin Therapy in Transient Neonatal Diabetes Mellitus.","authors":"Risa Sakai, Nobuyuki Kikuchi, Daisuke Nishi, Haruko Horiguchi","doi":"10.1155/2023/6667330","DOIUrl":"10.1155/2023/6667330","url":null,"abstract":"A sensor-augmented pump (SAP) therapy is used to treat neonatal diabetes mellitus (NDM). We treated a case for which SAP therapy was successful and prevented hypoglycemia. The patient was a baby boy who was small for his gestational age. He had hyperglycemia at 4 days of age, and a diagnosis of NDM had previously been made at another hospital. A continuous intravenous insulin infusion was initiated. At 29 days of age, the patient was transferred to our hospital for further treatment. SAP therapy was initiated at 39 days, which was successful and prevented hypoglycemia. Gradually, blood glucose levels improved. The insulin infusion was stopped to determine if any potential pump issues arose prior to discharge; the patient's blood glucose level did not increase. The decision was therefore made to discharge the patient from the hospital at 58 days of age with discontinued insulin. After discharge, genetic analysis showed hypomethylation on one of the alleles within 6q24, leading to a diagnosis of 6q24-related diabetes mellitus. Although almost all 6q24-related NDM cases are transient, no evidence exists for the appropriate timing of insulin discontinuation. Retrospective continuous glucose monitoring (CGM) analysis showed improved standard deviation (SD) values as well as improved blood glucose variability. This experience suggested SD values of CGM may be used as an index for tapering and discontinuing insulin in SAP therapy. However, future collaborative studies at other centers that focus on SD values as a guide for insulin discontinuation in SAP are required.","PeriodicalId":9623,"journal":{"name":"Case Reports in Pediatrics","volume":"2023 ","pages":"6667330"},"PeriodicalIF":0.9,"publicationDate":"2023-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10728360/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138798429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0