Caries Research最新文献

{"title":"Fluoride Dose-Response and Anticaries Effect of Herbal Antibacterial Agents and (Nano-)Hydroxyapatite on Dentin Caries: An in vitro Study.","authors":"Richard Johannes Wierichs, Mowliharan Kuruparan, Abinaya Ruthiraswaran, Hendrik Meyer-Lueckel, Thiago Saads Carvalho, Samira Helena Niemeyer","doi":"10.1159/000542953","DOIUrl":"10.1159/000542953","url":null,"abstract":"<p><strong>Introduction: </strong>The aim of the study was to investigate the caries-preventive effect of fluoride-free toothpastes, containing either herbal agents or (nano-)hydroxyapatite.</p><p><strong>Methods: </strong>Bovine dentin specimens each having a sound (ST) and a demineralized area (DT) were prepared and randomly allocated to eleven groups (n = 187). Treatments during pH cycling (28 days; 6 × 120 min demineralization/day) were brushing 2×/day with 0 ppm F- [NaF0], 500 ppm F- [NaF500], 1,100 ppm F- [NaF1100], grape seed extract [GSE], (nano-)hydroxyapatite, melaleuca oil [MO1, MO2, MO-CU], and propolis + myrrh [PM1, PM2] containing dentifrices. Dentifrice slurries were prepared with deionized water (1:3 w/w). Differences in integrated mineral loss (∆∆Z) and lesion depth (∆LD) were evaluated before and after pH cycling using transversal microradiography.</p><p><strong>Results: </strong>The correlation between ΔΔZ/ΔLD and F- concentration (NaF0, NaF500, NaF1100) was strong for the DT (rΔΔZ, DT = 0.681; p < 0.001) and very strong for ST (rΔΔZ, ST = 0.861; p < 0.001), indicating a fluoride dose-response for both baseline substrate conditions. For ΔΔZDT and ΔLDDT, only NaF1100 and GSE revealed significant differences compared with NaF0 (p < 0.001; ANOVA). For ΔΔZST and ΔLDST, significant differences could be found for NaF1100 and NaF500 compared to all fluoride-free groups (p ≤ 0.002; ANOVA), without significant difference between fluoride-free groups (p = 1.000; ANOVA). For DT and ST, a hypermineralized surface layer and no surface loss could only be observed when fluoride was present.</p><p><strong>Conclusion: </strong>A dose-response for fluoride concentrations was observed in this mild demineralization pH-cycling model. Fluoride-free dentifrices containing GSE or melaleuca oil showed certain preventive effect against further progression of root caries lesions. However, surface loss was observed for all fluoride-free dentifrices.</p>","PeriodicalId":9620,"journal":{"name":"Caries Research","volume":" ","pages":"1-12"},"PeriodicalIF":2.9,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142833948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Meta-Analysis of Global Distribution of Root-Caries Prevalence in Middle-Aged and Elderly.","authors":"Anastasia Maklennan, Roberta Borg-Bartolo, Andrea Roccuzzo, Claudia Salerno, Maria Katharina Raabe, Riccardo Monterubbianesi, Richard Johannes Wierichs, Marcela Esteves-Oliveira, Rodrigo A Giacaman, Guglielmo Campus","doi":"10.1159/000542783","DOIUrl":"10.1159/000542783","url":null,"abstract":"<p><strong>Introduction: </strong>Root caries (RC) remains a global health problem leading to negative impacts on an elderly person's well-being causing oral health-related quality of life issues, such as inadequate nutrition and detrimental oral functionality. The present systematic review with meta-analysis is designed to synthesize existing research findings on the prevalence and experience of root caries globally over the past 30 years. It aims to describe its distribution by country and explore its links with various socioeconomic indicators.</p><p><strong>Methods: </strong>Selection criteria: Three electronic databases (PubMed, Embase, and Scopus) were screened for observational epidemiological studies (cross-sectional and cohort studies) reporting the prevalence of RC and/or mean RC experience between 1990 and 2023. No languages were applied. Study selection, data extraction, and quality assessment were done in duplicate. Risk of bias was graded with customized quality assessment tools (Study Quality Assessment Tools NHLBI, NIH).</p><p><strong>Data collection and analysis: </strong>studies reporting on (1) root-caries experience (mean and SD) and (2) root-caries prevalence (%) were used to synthesize the results. It was assessed as decayed, missing, and filled teeth (RDMFT).</p><p><strong>Results: </strong>A total of 91 publications were included in the descriptive analysis; the estimated overall pooled mean RC was 2.87 teeth and the global estimated random-effects pooled RC prevalence was 41%. Low gross national income (GNI) countries reported a low mean number of RC (1.35 GNI <USD 5,000), while high GNI countries reported a higher mean number of RC (3.45 GNI USD 10,000-USD 19,999). Countries of higher inequalities (Gini index) reported lower means medium RC (1.98 teeth) than countries with no inequalities (4.90 teeth).</p><p><strong>Conclusion: </strong>This study highlights the high caries burden among adult population globally by estimating overall trends and comparing against factors including area, GNI, and Gini index. The large magnitude of these inequities indicates that oral health equity can only be achieved taking into account socioeconomic factors on a global scale. The lack of uniform data collecting among studies as well as knowledge gap regarding the incidence and experience of RC in different countries.</p>","PeriodicalId":9620,"journal":{"name":"Caries Research","volume":" ","pages":"1-17"},"PeriodicalIF":2.9,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142833949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Caries Impacts and Experiences and Dental Care Utilization for Saudi Schoolchildren: Caries Impacts and Experiences Questionnaire for Children - A Disease-Specific Measure.","authors":"Hesham Alhazmi, Abdulaziz I Koumu, Rawna H Alshaikh, Ahmed S Alfarsi, Lamyaa Y Alzahrani, Ghalia Y Bhadila, Sufana O Khalifa, Dania Bahdila","doi":"10.1159/000543132","DOIUrl":"10.1159/000543132","url":null,"abstract":"<p><strong>Introduction: </strong>The Caries Impacts and Experiences Questionnaire for Children (CARIES-QC) is a disease-specific questionnaire that assesses the impact of caries on the oral health-related quality of life of children. This study aimed to establish a baseline for caries-specific impact on schoolchildren in Saudi Arabia and to examine its association with dental care utilization.</p><p><strong>Methods: </strong>This cross-sectional study used random stratified cluster sampling among 4th-6th graders in Jeddah. Two surveys were administered: (1) a general parental survey and (2) CARIES-QC, a self-reported survey for children. Clinical examinations were conducted using the decayed, missing due to caries, and filled teeth (DMFT/dmft) index. Descriptive statistics provided CARIES-QC baseline estimates, and multilevel linear regression was performed to examine the relationships between CARIES-QC scores, DMFT/dmft index, and care utilization.</p><p><strong>Results: </strong>A total of 805 children aged 8-13 years participated. The overall median CARIES-QC score was six (interquartile range, 3-11). A higher DMFT/dmft index was associated with a higher CARIES-QC score (p < 0.05). Children who had never visited a dentist had lower CARIES-QC scores (β = -1.18, 95% confidence interval: -2.33; -0.02, p = 0.045) than those who had visited a dentist in the past 12 months. After adjusting for reasons for dental visits, the CARIES-QC scores were not associated with prior dental visits (p = 0.086).</p><p><strong>Conclusion: </strong>A higher DMFT/dmft index was associated with higher CARIES-QC scores, but prior dental care utilization was not significantly associated with improved CARIES-QC scores. Future research should explore other factors that influence the relationship between care utilization and caries-specific quality of life.</p>","PeriodicalId":9620,"journal":{"name":"Caries Research","volume":" ","pages":"1-10"},"PeriodicalIF":2.9,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142833947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accuracy of Near-Infrared Imaging in Detection of Proximal Caries Lesions in Deciduous Molars: An in vitro Study.","authors":"Suzana Oliveira, Regina Siegl, Kelly Moreira, Ana Flávia Calvo, José Carlos Pettorossi Imparato, Thais Gimenez","doi":"10.1159/000543110","DOIUrl":"10.1159/000543110","url":null,"abstract":"<p><strong>Introduction: </strong>The aim of this in vitro study was to evaluate the accuracy of near-infrared imaging (NIRI) generated by the iTero Element 5D scanner for detecting proximal caries lesions in deciduous molars, compared with visual inspection (VI), bitewing (BW) radiography, and histological examination (reference standard).</p><p><strong>Methods: </strong>Sound deciduous molars and those with caries lesions (ICDAS 0 to 5) on the proximal surface were included, while teeth with marginal crest breakdown, restoration on the mentioned surfaces, or extensive dentin resorption were excluded. A total of 182 deciduous molars, divided into 91 pairs of first and second molars, were evaluated by two blinded examiners. Two distinct thresholds were considered for the assessment of caries detection methods: enamel lesion (D1) and dentin lesion (D3). Specificity, sensitivity, accuracy, and area under the ROC curve (AUC) were calculated for each method in the statistical analysis.</p><p><strong>Results: </strong>All evaluated methods demonstrated high specificity at D1, with 1.00 for VI and 0.95 for NIRI and BW, and at D3, 0.99 for BW and 0.98 for NIRI and VI, without statistical differences. The sensitivity and accuracy of NIRI at D1 were 0.44 and 0.55, while those of VI were 0.46 and 0.58, and of BW were 0.60 and 0.68, respectively. And sensitivity and accuracy of NIRI at D3 were 0.14 and 0.69, while those of VI were 0.37 and 0.77, and of BW were 0.51 and 0.82, respectively. No difference in sensitivity and accuracy was observed between NIRI and VI at D1 (p = 0.589); however, NIRI presented the lowest accuracy at D3. At D1, no statistical difference was observed between the AUC of BW and VI (p = 0.1124), nor between NIRI and VI (p = 0.2523). However, at D3, statistical differences were observed between the AUCs of the three evaluated methods: VI versus NIRI (p = 0.0005), VI versus BW (p = 0.0281), and NIRI versus BW (p < 0.0001).</p><p><strong>Conclusion: </strong>NIRI showed accuracy comparable to VI at the D1 threshold but was less effective than BW radiography at both D1 and D3 thresholds.</p>","PeriodicalId":9620,"journal":{"name":"Caries Research","volume":" ","pages":"1-10"},"PeriodicalIF":2.9,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142833946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Influence of Social Support, Oral Health Beliefs, and Health Behaviours on Dental Caries in Children Living in Deprived Neighbourhoods.","authors":"Mylla Cristie Campelo Monteiro, Maria Augusta Bessa Rebelo, Yan Nogueira Leite de Freitas, Janete Maria Rebelo Vieira, Mario Vianna Vettore","doi":"10.1159/000542938","DOIUrl":"10.1159/000542938","url":null,"abstract":"<p><strong>Introduction: </strong>This study assessed the influence of social support, oral health beliefs, and health behaviours on dental caries incidence among children living in underprivileged neighbourhoods.</p><p><strong>Methods: </strong>Data from a cohort study with 12-year-old schoolchildren (N = 312) selected from public schools in Manaus, Brazil, and their parents or guardians were analysed. Socio-economic characteristics, sex, oral health beliefs, social support (SSA questionnaire), oral health-related behaviours (sugar consumption, frequency of toothbrushing, use of fluoride toothpaste), and dental caries (DMFT index) were assessed at age 12 years. Dental caries incidence over 12-month period was registered according to the number of new cavitated teeth. The hypothesis was that socio-economic disadvantage, lower social support, unfavourable oral health beliefs, and inadequate behaviours would increase the risk of dental caries incidence. Statistical analysis was conducted using confirmatory factor analysis and structural equation modelling.</p><p><strong>Results: </strong>Unfavourable oral health beliefs indirectly predicted higher dental caries incidence (β = 0.041) via sugar consumption and frequency of toothbrushing. Unfavourable oral health beliefs directly predicted higher sugar consumption (β = 0.148) and lower frequency of toothbrushing (β = -0.218). Lower frequency of toothbrushing directly predicted higher dental caries incidence (β = -0.140). Sex (β = -0.017) and social support (β = -0.016) were indirectly linked to dental caries incidence.</p><p><strong>Conclusions: </strong>Our findings suggest that incidence of dental caries in socially underprivileged children results from the complex relationships between social support, oral health beliefs, and oral health behaviours.</p>","PeriodicalId":9620,"journal":{"name":"Caries Research","volume":" ","pages":"1-8"},"PeriodicalIF":2.9,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142806012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to the Letter by Costa and Bittencourt Santos regarding Predictors of Developmental Defects of Enamel in Primary Maxillary Central Incisors Using Bayesian Model Selection.","authors":"Susan G Reed, Sijian Fan, Carol L Wagner, Andrew B Lawson","doi":"10.1159/000542911","DOIUrl":"10.1159/000542911","url":null,"abstract":"","PeriodicalId":9620,"journal":{"name":"Caries Research","volume":" ","pages":"1-2"},"PeriodicalIF":2.9,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142779426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Geographical Distribution of Dental Caries Prevalence and Associated Factors in Young Males in Finland 2021: A Cross-Sectional Study.","authors":"Elias Laaksonen, Tarja Tanner, Pertti Patinen, Jari Päkkilä, Leo Tjäderhane, Vuokko Anttonen, Antti Kämppi","doi":"10.1159/000542212","DOIUrl":"10.1159/000542212","url":null,"abstract":"<p><strong>Introduction: </strong>Finnish conscripts have proven to be an excellent study group for epidemiological research in oral health in recent decades. The aim of this cross-sectional study was to determine the geographical distribution of dental caries prevalence in young healthy males in Finland at the beginning of the 2020s. Associated dental caries risk factors were of interest as well.</p><p><strong>Methods: </strong>The data were randomly collected from the eight biggest garrisons in Finland in July of 2021 by ten calibrated dentists. The study population consisted of 2077 male conscripts born between 2000 and 2002. Dental caries was recorded according to the ICDAS system. Wisdom teeth were excluded. Mean DMFT and mean DT values were calculated, and geomaps were constructed to visualize the geographical distribution. Generalized linear mixed models with logit link were conducted for the associated risk factors.</p><p><strong>Results: </strong>The mean DMFT value of all conscripts was 3.29 (SD 3.91), while the mean DT value was 1.19 (SD 2.33). Living in areas with endemic fluoride levels in drinking water ≥0.3 mg/L decreased the odds for restorative treatment need.</p><p><strong>Conclusion: </strong>While geographical distribution of dental caries prevalence has remained nearly the same as before, the overall restorative treatment need and treatment history have decreased countrywide.</p>","PeriodicalId":9620,"journal":{"name":"Caries Research","volume":" ","pages":"1-9"},"PeriodicalIF":2.9,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142766521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of and Factors Influencing Oral Health Behaviours in 2-Year-Old Children: A Cross-Sectional Analysis of Data from the KUNO-Kids Health Study.","authors":"Áine M Lennon, Christoph Musiol, Karl-Anton Hiller, Nils Gade, Wolfgang Buchalla, Susanne Brandstetter, Angela Köninger, Michael Melter, Christian Apfelbacher, Michael Kabesch","doi":"10.1159/000542913","DOIUrl":"10.1159/000542913","url":null,"abstract":"<p><strong>Introduction: </strong>This questionnaire-based investigation aimed to assess oral health behaviour (OHB) in 2-year-old children taking part in a birth cohort study and to identify relationships between general health, socioeconomic as well as psychosocial factors and OHB.</p><p><strong>Methods: </strong>Factors examined were single-parent status, migration background, child's sex, parity, maternal age, education and social support, paternal employment, parental mental and physical health, and child health, data for which were collected at birth, 4 weeks, or 1 year. Participants who answered all OHB questions at 2 years (n = 730) were included. Nutritional score (NS), toothbrushing score (TS), and dental check-up score (CS) were used to calculate overall OHB score.</p><p><strong>Results: </strong>Overall OHB in this cohort was good. 62% ate fruit or vegetables daily, 75% brushed 2-3 times daily, and 61% had already had a dental check-up. Children of single mothers had significantly lower OHB scores. NS was significantly higher for children with migration background, children of mothers with better physical health or higher educational level, but lower for children of mothers reporting poor social support. TS was significantly lower in children of single mothers and children of fathers reporting poorer mental health. CS was significantly higher in children of multiparous mothers. This study highlights the relevance of social support and parental health, in contributing to OHB patterns.</p><p><strong>Conclusion: </strong>Families with special healthcare needs or less robust social support may have difficulty maintaining good OHB.</p>","PeriodicalId":9620,"journal":{"name":"Caries Research","volume":" ","pages":"1-18"},"PeriodicalIF":2.9,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142766523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Selective Outcome Reporting Bias in Randomized Controlled Trials on Dental Caries in Children and Adolescents: A Meta-Research Study.","authors":"Livia da Rosa Oliveira, Rokaia Ahmed Elagami, Thais Marchezini Reis, Tamara Kerber Tedesco, Fausto Medeiros Mendes, Mariana Minatel Braga, Claudio Mendes Pannuti, Daniela Prócida Raggio","doi":"10.1159/000542108","DOIUrl":"10.1159/000542108","url":null,"abstract":"<p><strong>Introduction: </strong>Selective outcome reporting (SOR) is a bias that can occur in randomized controlled trials (RCTs), defined as the alteration or omission of primary outcome in the publication compared to the original protocol. Researchers may modify outcomes to highlight statistically significant results. This study aimed to assess the prevalence of SOR in RCTs related to dental caries in children and adolescents.</p><p><strong>Methods: </strong>We conducted a search on <ext-link ext-link-type=\"uri\" xlink:href=\"http://ClinicalTrials.gov\" xmlns:xlink=\"http://www.w3.org/1999/xlink\">ClinicalTrials.gov</ext-link> and the International Clinical Trials Registry Platform (ICTRP), using a comprehensive search strategy with terms related to pediatric dentistry and dental caries, up to February 2023. Two independent reviewers included trials with two or more arms focusing on dental caries in pediatric dentistry. Registrations that did not result in at least one published article were excluded. Data on the characteristics and outcomes from the protocols and corresponding publications were extracted. The primary outcome was the prevalence of SOR in the included RCTs. A chi-square test, with a significance level of 5%, was used to assess the association between SOR and pre-specified variables, which was the secondary outcome.</p><p><strong>Results: </strong>A total of 175 protocols and their corresponding publications were included. SOR was identified in 58.9% (n = 103) of the studies, with 41.1% (n = 72) showing discrepancies in the primary outcome's time frame. Retrospective registrations accounted for 73.7% of the studies. SOR was significantly associated with discrepancies in the follow-up period (p < 0.001) and with study design type (parallel assignment, split-mouth, cluster RCT, and no information) (p = 0.048).</p><p><strong>Conclusions: </strong>The high prevalence of SOR in dental caries RCTs in pediatric dentistry highlights the need for attention to this issue. Ensuring transparency in the research process requires implementing an appropriate pre-registered protocol, disclosing deviations from it, and enabling stakeholders to compare the protocol with the published outcomes which can help reduce research waste.</p>","PeriodicalId":9620,"journal":{"name":"Caries Research","volume":" ","pages":"1-12"},"PeriodicalIF":2.9,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142726068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is Poor Self-Rated Health Associated with Higher Caries Experience in Adults? The HUNT4 Oral Health Study.","authors":"Siri Christine Rødseth, Hedda Høvik, Espen Bjertness, Rasa Skudutyte-Rysstad","doi":"10.1159/000542522","DOIUrl":"10.1159/000542522","url":null,"abstract":"<p><strong>Introduction: </strong>The association between lower socioeconomic status and a higher risk of dental caries is well established, but the independent association between general health status and dental caries on a population level is less investigated. The aim of this study was to assess the association between self-rated general health and caries experience in an adult Norwegian population and to assess if the associations were modified by age and sex.</p><p><strong>Methods: </strong>Data were collected as part of the Trøndelag Health Study (HUNT4) conducted 2017-2019 and a randomly selected subsample (20%) were invited for the HUNT4 Oral Health Study. This cross-sectional study included 4,880 dentate participants aged 19-94 years (response rate 67%). Participants underwent clinical and radiographic oral examinations and caries experience was measured by numbers of decayed (DT), missing (MT), and filled teeth (FT), DMFT index. The DT component consisted of primary and secondary caries in dentine, cavitated root caries, and remaining roots. Questionnaires were used to assess self-rated general health and socioeconomic position, denoted by education, household income, and employment status. Associations between self-rated health and caries experience (DMFT) and components (DT, MT, and FT) were assessed using negative binomial regression models. Ratios of means (RMs) with 95% confidence intervals (CI) for the associations were estimated, adjusting for socioeconomic position.</p><p><strong>Results: </strong>Individuals with poor self-rated general health had a 29% higher mean number of MT (RM: 1.29 [95% CI: 1.13-1.46]), a 22% higher mean number of DT (RM: 1.22 [95% CI: 1.07-1.39]), and a 7% higher mean number of DMFT (RM: 1.07 [95% CI: 1.04-1.11]) than individuals reporting very good health. Age-stratified analyses presented a more pronounced association between self-rated health and caries experience for individuals below the age of 55 years than for those 55 years or older. Similarly, the association was more evident in women, with significantly higher mean values for DMFT, MT, and FT among women reporting poor health.</p><p><strong>Conclusions: </strong>The present study demonstrated an independent association between poor self-rated health and a higher burden of caries experience, adjusted for education, income, and employment status. The association was stronger in women and individuals below the age of 55 years. These findings add new evidence in understanding caries inequalities through self-rated health.</p>","PeriodicalId":9620,"journal":{"name":"Caries Research","volume":" ","pages":"1-12"},"PeriodicalIF":2.9,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142615499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}