Canadian journal of ophthalmology. Journal canadien d'ophtalmologie最新文献_第5页

Acute angle-closure glaucoma risk: a comparative study of escitalopram and antidepressants.

IF 3.3 4区医学

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie Pub Date : 2025-02-05 DOI: 10.1016/j.jcjo.2025.01.004

Haaris M Khan, Steven Schendel, Frederick S Mikelberg, Mahyar Etminan

引用次数: 0

Insights into the effects of subretinal voretigene neparvovec-rzyl in RPE65-associated Leber congenital amaurosis. 视网膜下voretigene neparvovec-rzyl治疗rpe65相关Leber先天性黑蒙的疗效：一份18个月的报告

IF 3.3 4区医学

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie Pub Date : 2025-02-05 DOI: 10.1016/j.jcjo.2024.12.006

Alaa Tayyib, Deepika C Parameswarappa, Peter J Kertes, Rajeev Muni, Anupreet Tumber, Gregory Costain, Alex Schramm, Heather MacDonald, Regan Klatt, Ajoy Vincent, Elise Héon

{"title":"Insights into the effects of subretinal voretigene neparvovec-rzyl in RPE65-associated Leber congenital amaurosis.","authors":"Alaa Tayyib, Deepika C Parameswarappa, Peter J Kertes, Rajeev Muni, Anupreet Tumber, Gregory Costain, Alex Schramm, Heather MacDonald, Regan Klatt, Ajoy Vincent, Elise Héon","doi":"10.1016/j.jcjo.2024.12.006","DOIUrl":"10.1016/j.jcjo.2024.12.006","url":null,"abstract":"<p><strong>Objective: </strong>Assess safety and effectiveness of subretinal gene replacement therapy at 18 months post treatment.</p><p><strong>Design: </strong>Retrospective, longitudinal study conducted at the Hospital for Sick Children in Toronto, Canada.</p><p><strong>Participants: </strong>Patients with bi-allelic RPE65 variants, early onset retinal degeneration, and residual viable retina who underwent voretigene neparvovec r-zyl gene replacement therapy.</p><p><strong>Methods: </strong>Data collected included demographic information, molecular genetic results, and comprehensive ocular assessment results from preoperataive and postoperative visits up to 18 months. To assess the treatment's efficacy, postoperative best corrected visual acuity, full-field stimulus test (FST), visual field (VF) area, optical coherence tomography, and global satisfaction were compared to preoperative findings.</p><p><strong>Results: </strong>The procedures were safe with no complications. There was no significant improvement in visual acuity. Three eyes showed a slight reduction in VF area. All showed a reduction in ellipsoid zone thickness and area, but the outer nuclear layer thickness and area were stable. All had a significant improvement in retinal sensitivity, as per FST, allowing better navigation in a dim environment. All 3 patients reported being \"very satisfied\".</p><p><strong>Conclusion: </strong>Following a safe gene replacement therapy, the 3 first Canadian cases had an improvement in retinal sensitivity as per FST, and our patients described their experience as positively life changing.</p>","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143000563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessing the performance of Microsoft Copilot, GPT-4 and Google Gemini in ophthalmology. 评估 Microsoft Copilot、GPT-4 和 Google Gemini 在眼科方面的性能。

IF 3.3 4区医学

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie Pub Date : 2025-02-04 DOI: 10.1016/j.jcjo.2025.01.001

Meziane Silhadi, Wissam B Nassrallah, David Mikhail, Daniel Milad, Mona Harissi-Dagher

{"title":"Assessing the performance of Microsoft Copilot, GPT-4 and Google Gemini in ophthalmology.","authors":"Meziane Silhadi, Wissam B Nassrallah, David Mikhail, Daniel Milad, Mona Harissi-Dagher","doi":"10.1016/j.jcjo.2025.01.001","DOIUrl":"10.1016/j.jcjo.2025.01.001","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the performance of large language models (LLMs), specifically Microsoft Copilot, GPT-4 (GPT-4o and GPT-4o mini), and Google Gemini (Gemini and Gemini Advanced), in answering ophthalmological questions and assessing the impact of prompting techniques on their accuracy.</p><p><strong>Design: </strong>Prospective qualitative study.</p><p><strong>Participants: </strong>Microsoft Copilot, GPT-4 (GPT-4o and GPT-4o mini), and Google Gemini (Gemini and Gemini Advanced).</p><p><strong>Methods: </strong>A total of 300 ophthalmological questions from StatPearls were tested, covering a range of subspecialties and image-based tasks. Each question was evaluated using 2 prompting techniques: zero-shot forced prompting (prompt 1) and combined role-based and zero-shot plan-and-solve+ prompting (prompt 2).</p><p><strong>Results: </strong>With zero-shot forced prompting, GPT-4o demonstrated significantly superior overall performance, correctly answering 72.3% of questions and outperforming all other models, including Copilot (53.7%), GPT-4o mini (62.0%), Gemini (54.3%), and Gemini Advanced (62.0%) (p < 0.0001). Both Copilot and GPT-4o showed notable improvements with Prompt 2 over Prompt 1, elevating Copilot's accuracy from the lowest (53.7%) to the second highest (72.3%) among the evaluated LLMs.</p><p><strong>Conclusions: </strong>While newer iterations of LLMs, such as GPT-4o and Gemini Advanced, outperformed their less advanced counterparts (GPT-4o mini and Gemini), this study emphasizes the need for caution in clinical applications of these models. The choice of prompting techniques significantly influences performance, highlighting the necessity for further research to refine LLMs capabilities, particularly in visual data interpretation, to ensure their safe integration into medical practice.</p>","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143037245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Complication rates in cataract surgery before and during the COVID-19 pandemic.

IF 3.3 4区医学

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie Pub Date : 2025-02-03 DOI: 10.1016/j.jcjo.2024.12.001

Lee-Wing Nathan, Stockl Frank, Wiens James

{"title":"Complication rates in cataract surgery before and during the COVID-19 pandemic.","authors":"Lee-Wing Nathan, Stockl Frank, Wiens James","doi":"10.1016/j.jcjo.2024.12.001","DOIUrl":"https://doi.org/10.1016/j.jcjo.2024.12.001","url":null,"abstract":"<p><strong>Objective: </strong>To assess the cataract surgery (CS) complication rates before and during the COVID-19 pandemic.</p><p><strong>Design: </strong>Retrospective, cross sectional study.</p><p><strong>Methods: </strong>Medical records of patients undergoing CS at two surgery centers in Winnipeg from January 2018 to April 2022 were reviewed. The study periods were pre-COVID-19 (January 1, 2018 to March 31, 2020) and COVID-19 (April 1, 2020 to April 30, 2022). Complication rates for endophthalmitis, sulcus-positioned intraocular lens (IOL) implant, anterior chamber IOL (ACIOL) implant, capsular tension ring (CTR) insertion, cumulative dissipated phacoemulsification energy (CDE), posterior capsular rupture (PCR), unplanned anterior vitrectomy, and return to the OR within one month of surgery were compared.</p><p><strong>Results: </strong>45,559 patients were included. Pre-COVID-19 rates were compared to COVID-19 rates and stated as per 100 cataract surgeries. Endophthalmitis rates increased from 0.008 to 0.028 (RR 0.27, p=0.09). Sulcus IOL implant rates increased from 0.61 to 1.00 (RR 0.61, p<0.0001). ACIOL implant rates increased from 0.53 to 0.68 (RR 0.78, p=0.05). CTR usage rates increased from 0.48 to 0.75 (RR 0.63, p=0.001). Average CDE increased from 4.6 to 6.7 (p=0.0030). PCR rates decreased from 0.49 to 0.38 (RR 1.3, p=0.14). Unplanned anterior vitrectomy rates decreased from 0.43 to 0.36 (RR 1.18, p=0.35). Return to OR rates remained unchanged at 0.59 and 0.58 (RR 1.01, p=0.93).</p><p><strong>Conclusions: </strong>Our study found significant increases in some CS complication rates when comparing the defined pre-COVID interval to the COVID interval.</p>","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143188399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exudative subretinal fluid associated with tebentafusp immunotherapy 与特本福斯免疫疗法相关的渗出性视网膜下积液。

IF 3.3 4区医学

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie Pub Date : 2025-02-01 DOI: 10.1016/j.jcjo.2024.08.003

Joana Andoh, Loka Thangamathesvaran, J. Fernando Arevalo

引用次数: 0

Clinical outcomes and characterization of intraocular foreign body injuries from a Canadian centre: a 20-year retrospective study and literature review 加拿大某中心眼内异物损伤的临床结果和特征：20 年回顾性研究和文献综述。

IF 3.3 4区医学

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie Pub Date : 2025-02-01 DOI: 10.1016/j.jcjo.2024.05.019

Abdullah Al-Ani , Mohamed S Bondok , Kian Madjedi , Shellina Kherani , Amin Kherani

{"title":"Clinical outcomes and characterization of intraocular foreign body injuries from a Canadian centre: a 20-year retrospective study and literature review","authors":"Abdullah Al-Ani , Mohamed S Bondok , Kian Madjedi , Shellina Kherani , Amin Kherani","doi":"10.1016/j.jcjo.2024.05.019","DOIUrl":"10.1016/j.jcjo.2024.05.019","url":null,"abstract":"<div><h3>Objectif</h3><div>Analyser l’évaluation et la prise en charge des corps étrangers intraoculaires (CEIO) en milieu urbain au Canada pour générer une perspective clinique précieuse afin de replacer la prise en charge dans son contexte.</div></div><div><h3>Méthodes</h3><div>Examen rétrospectif des dossiers médicaux des patients d'un seul chirurgien datés de janvier 2002 à janvier 2023 comprenant les caractéristiques démographiques de patients qui ont eu un CEIO, leurs examens, leurs traitements, leurs complications et leur meilleure acuité visuelle corrigée (MAVC).</div></div><div><h3>Résultats</h3><div>Notre étude a porté sur la présence d'un CEIO dans 32 yeux de 31 patients (96,8 % des patients étaient de sexe masculin). La taille du CEIO variait de 1 à 12 mm; 28 corps étrangers (87,5 %) étaient en métal; il s'agissait d'un accident de travail dans 15 cas (46,9 %). Dans le cadre de l'examen diagnostique, 19 patients (61,3 %) ont fait l'objet d'une tomographie assistée par ordinateur (TAO), et 8 patients (25,8 %), d'une échographie oculaire (B-scan). La TAO a permis de déceler les CEIO dans 100 % des cas, et les B-scans, dans 87,5 % des cas. Lors du suivi final, la MAVC de 17 yeux (53,1 %) était ≥ 20/40, comparativement à 7 yeux (23,3 %) au départ. Une MAVC ≥ 20/200 lors de l'examen initial était associée à une MAVC finale ≥ 20/40 (<em>p</em> = 0,027). Le CEIO a pu être retiré dans 27 yeux (84,4 %), est demeuré en place dans 4 yeux (12,5 %) et a entraîné l’énucléation de 1 œil (3,1 %). Des antibiotiques ont été administrés par voie intravitréenne dans 19 yeux (59,4 %), ce qui a donné lieu à 1 cas présumé de toxicité médicamenteuse. Des complications sont survenues dans 30 yeux (93,8 %) pour un total de 119, dont 72 (60,5 %) sont apparues pendant les 24 premières heures. La cataracte post-traumatique était la complication la plus fréquente (27 yeux; 84,4 %). Les complications moins fréquentes comprenaient la sidérose oculaire et le décollement de la rétine s'accompagnant d'une vitréorétinopathie proliférante (chacune ayant touché 1 œil; 3,1 %). Enfin, un glaucome secondaire est apparu dans 4 yeux (12,5 %), dont 3 où le CEIO était demeuré en place ou avait été extrait tardivement.</div></div><div><h3>Conclusions</h3><div>Les caractéristiques des CEIO et les paramètres démographiques des patients cadrent avec ceux d'autres régions. La TAO était l'outil d'examen le plus efficace. On recommande un suivi prolongé pour surveiller les complications, surtout en cas de rétention du CEIO ou lorsque son extraction est significativement retardée.</div></div>","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":"60 1","pages":"Pages e83-e91"},"PeriodicalIF":3.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141878441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multicentre analysis of nucleic acid quantification using aqueous humour liquid biopsy in uveal melanoma: implications for clinical testing 在葡萄膜黑色素瘤中应用体液活检进行核酸定量的多中心分析:临床试验的意义。

IF 3.3 4区医学

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie Pub Date : 2025-02-01 DOI: 10.1016/j.jcjo.2023.10.024

Sarah B. Pike , Mark W Reid , Chen-Ching Peng , Christina Chang , Benjamin Y. Xu , Dan S. Gombos , Sapna Patel , Liya Xu , Jesse L. Berry

{"title":"Multicentre analysis of nucleic acid quantification using aqueous humour liquid biopsy in uveal melanoma: implications for clinical testing","authors":"Sarah B. Pike , Mark W Reid , Chen-Ching Peng , Christina Chang , Benjamin Y. Xu , Dan S. Gombos , Sapna Patel , Liya Xu , Jesse L. Berry","doi":"10.1016/j.jcjo.2023.10.024","DOIUrl":"10.1016/j.jcjo.2023.10.024","url":null,"abstract":"<div><h3>Objective</h3><div><span>Uveal melanoma<span><span> (UM) tumour biopsy is limited by size and intratumour heterogeneity. We explored the potential of </span>aqueous humour (AH) </span></span>liquid biopsy<span> for UM by quantifying analytes in samples collected at diagnosis and after brachytherapy to look for clinical correlations with tumour features.</span></div></div><div><h3>Design</h3><div>Case-series study.</div></div><div><h3>Participants</h3><div>Sixty-six UM patients and 16 control subjects from a tertiary care hospital.</div></div><div><h3>Methods</h3><div><span><span>The study included 119 UM AH samples and 16 control samples analyzed for unprocessed analytes (i.e., dsDNA, </span>miRNA, and protein) using </span>Qubit<span> fluorescence assays.</span></div></div><div><h3>Results</h3><div><span>Analytes were widely quantifiable among available UM AH samples (dsDNA: 94.1%; miRNA: 88.0%; protein: 95.2%) at significantly higher concentrations than among control samples (dsDNA, </span><em>p</em><span> = 0.008; miRNA, </span><em>p</em> < 0.0001; protein, <em>p</em><span><span> = 0.007). In samples taken at diagnosis, concentrations were higher at more advanced American Joint Cancer Commission stages; when comparing most advanced stage III with least advanced stage I, median </span>dsDNA was 4 times greater (</span><em>p</em> < 0.0001), miRNA was 2 times greater (<em>p</em> = 0.001), and protein was 3 times greater (<em>p</em> < 0.0001). Analytes were quantifiable in >70% of diagnostic samples from eyes with tumours <2 mm tall. Height had a positive association with diagnostic analyte concentrations (dsDNA: <em>R</em> = 0.43, <em>p</em> = 0.0007; miRNA: <em>R</em> = 0.35, <em>p</em> = 0.01; protein: <em>R</em> = 0.39, <em>p</em> = 0.005). Samples taken after brachytherapy showed significantly higher concentrations than diagnostic samples (<em>p</em> < 0.01 for all).</div></div><div><h3>Conclusions</h3><div>UM AH is a rich repository of analytes. Samples from eyes with more advanced stage and larger tumours had higher concentrations, though analytes also were quantifiable in eyes with smaller, less advanced tumours. Future analysis of AH analytes may be informative in the pursuit of personalized UM treatments.</div></div><div><h3>Objectif</h3><div>En présence d'un mélanome de l'uvée (MU), la biopsie de la tumeur est limitée par sa taille et par l'hétérogénéité intratumorale. Nous avons examiné l'intérêt de la biopsie liquide de l'humeur aqueuse (HA) dans le MU en quantifiant les analytes dans les échantillons recueillis au moment du diagnostic et après la curiethérapie afin de faire ressortir des corrélations cliniques en lien avec les caractéristiques de la tumeur.</div></div><div><h3>Nature</h3><div>Série de cas.</div></div><div><h3>Participants</h3><div>L’étude portait sur 66 patients présentant un MU et 16 sujets témoins provenant d'un hôpital de soins tertiaires.</div></div><div><h3>Méthodes</h3><div>L’étude co","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":"60 1","pages":"Pages e23-e31"},"PeriodicalIF":3.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138458103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reperfusion of macular vasculature in lupus-mediated occlusive vasculopathy 狼疮介导的闭塞性血管病变中黄斑部血管的再灌注。

IF 3.3 4区医学

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie Pub Date : 2025-02-01 DOI: 10.1016/j.jcjo.2024.07.016

Peter J. Weng, Dilraj S. Grewal

引用次数: 0

Ocular screening for chronic graft-versus-host disease in patients with allogeneic hematopoietic stem cell transplant 异体造血干细胞移植患者慢性移植物抗宿主疾病的眼部筛查

IF 3.3 4区医学

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie Pub Date : 2025-02-01 DOI: 10.1016/j.jcjo.2024.04.005

Bryan G. Pearson , Ray S. Cortez , Karima S. Khimani , Praveena K. Gupta

{"title":"Ocular screening for chronic graft-versus-host disease in patients with allogeneic hematopoietic stem cell transplant","authors":"Bryan G. Pearson , Ray S. Cortez , Karima S. Khimani , Praveena K. Gupta","doi":"10.1016/j.jcjo.2024.04.005","DOIUrl":"10.1016/j.jcjo.2024.04.005","url":null,"abstract":"<div><h3>Objective</h3><div>This study investigates ocular manifestations of graft-versus-host disease in patients following allogeneic hematopoietic stem cell transplantation (HSCT) at the University of Texas Medical Branch (UTMB). Preferred practice pattern guidelines are proposed for ocular graft-versus-host disease (oGHVD) detection.</div></div><div><h3>Methods</h3><div><span>The Epic electronic medical record database at UTMB was screened using </span><em>International Classification of Diseases</em><span><span><span>, Tenth Revision (ICD-10), codes for bone marrow transplants, </span>stem cell transplants, and complications of bone marrow transplants and stem cell transplants. We identified 50 patients with the ICD-10 codes that were seen at UTMB between 2000 and 2021. Patients who received an </span>HSCT and follow-up care with UTMB were included in this study. Thirty-eight patients met the inclusion criteria, whereas 12 patients were excluded because they had no diagnosis of HSCT or did not follow-up with UTMB.</span></div></div><div><h3>Results</h3><div><span>Of the 38 patients in our cohort, 23.7% (n = 9) were noted to have oGVHD. As many as 89% of the patients with oGVHD presented with an ocular surface disease including </span>keratoconjunctivitis sicca<span>, meibomian gland dysfunction<span>, and dry eye syndrome. Systemic GVHD also was found in 44% of the patients with oGVHD. Only 29% (n = 11) of the study population had referrals to ophthalmology. Most referrals (55%) were made within 1 year of getting the HSCT. None of the patients in our cohort received an ocular screening before HSCT.</span></span></div></div><div><h3>Conclusions</h3><div>Many post-HSCT patients lack routine ophthalmic<span> care. Regularly assessing post-HSCT patients for early signs and symptoms of oGVHD may limit adverse outcomes. Management of oGVHD should involve a multidisciplinary team approach.</span></div></div><div><h3>Objectif</h3><div>La présente étude se penche sur les manifestations oculaires de la maladie du greffon contre l'hôte (MGCH) chez des patients qui ont reçu une allogreffe de cellules souches hématopoïétiques (ACSH) à la faculté de médecine de l'Université du Texas (UTMB, pour University of Texas Medical Branch). On y propose des lignes directrices en matière de pratiques courantes privilégiées (<em>Preferred Practice Pattern® Guidelines</em> de l'AAO) en vue du dépistage de la MGCH oculaire.</div></div><div><h3>Méthodes</h3><div>On a extrait les codes correspondant aux greffes de moelle osseuse et aux greffes de cellules souches de même qu’à leurs complications selon la classification internationale des maladies (CIM-10) dans la base de données des dossiers médicaux électroniques Epic de l'UTMB. On a ainsi recensé 50 patients auxquels on a attribué ces codes à l'UTMB entre 2000 et 2021. Seuls les patients qui ont reçu une ACSH à l'UTMB et qui y ont été suivis ont été inclus dans notre étude : 38 patients répondaient aux critères d'inclu","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":"60 1","pages":"Pages e11-e15"},"PeriodicalIF":3.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141145696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relation between change of effective lens position and toric IOL rotation after toric IOL implantation 散光人工晶体植入术后有效晶状体位置变化与散光人工晶体旋转之间的关系

IF 3.3 4区医学

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie Pub Date : 2025-02-01 DOI: 10.1016/j.jcjo.2024.05.011

Kyung-Sun Na , Dohyeon An , Hyun Seung Kim , Eun Chul Kim

{"title":"Relation between change of effective lens position and toric IOL rotation after toric IOL implantation","authors":"Kyung-Sun Na , Dohyeon An , Hyun Seung Kim , Eun Chul Kim","doi":"10.1016/j.jcjo.2024.05.011","DOIUrl":"10.1016/j.jcjo.2024.05.011","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the relationship between change of effective lens position (ELP) and toric intraocular lens<span><span> (IOL) rotation in patients with increasing postoperative refractive astigmatism after successful toric </span>IOL implantation.</span></div></div><div><h3>Methods</h3><div><span>The subjects include 61 people (61 eyes) with increasing residual astigmatism >0.5 D 3 months after successful toric IOL implantation. Clinical measurements included preoperative, 1-week, and 1-, 2-, and 3-month postoperative visual acuity; refraction; </span>keratometer<span>; anterior and posterior corneal astigmatism; ELP by Scheimpflug camera imaging; and IOL axis by slit-lamp biomicroscopic photograph with pupil dilation.</span></div></div><div><h3>Results</h3><div>Residual astigmatism in postoperative month 3 (0.81 ± 0.50 D) is higher than that at postoperative week 1 (0.41 ± 0.38 D; <em>p</em> < 0.05). ELP decreased by 264.44 ± 163.25 μm, and the IOL rotated by 2.91 ± 1.44 degrees from week 1 to month 3 (<em>p</em> < 0.05). The ELP change had a positive correlation with IOL rotation (<em>R</em><sup>2</sup> = 0.383; <em>p</em> = 0.006), and the postoperative refractive astigmatic change had a positive correlation with ELP change (<em>R</em><sup>2</sup> = 0.272; <em>p</em> = 0.027) and IOL rotation (<em>R</em><sup>2</sup> = 0.272; <em>p</em> = 0.0001) from week 1 to month 3.</div></div><div><h3>Conclusion</h3><div>ELP change can influence toric IOL rotation and increase residual astigmatism after toric IOL implantation.</div></div><div><h3>Objectif</h3><div>Évaluer le lien entre une modification de la position effective de l'implant (PEI) et la rotation d'une lentille intraoculaire (LIO) torique chez des patients qui présentent un astigmatisme réfractif postopératoire progressif après l'implantation réussie d'une LIO torique.</div></div><div><h3>Méthodes</h3><div>L’étude regroupait 61 patients (61 yeux) qui présentaient un astigmatisme résiduel progressif de > 0,5 D 3 mois après l'implantation réussie d'une LIO torique. Les mesures cliniques comprenaient les suivantes: l'acuité visuelle préopératoire et postopératoire (après 1 semaine et après 1, 2 et 3 mois), la réfraction, la kératométrie, l'astigmatisme cornéen (antérieur et postérieur), la PEI mesurée par imagerie Scheimpflug et l'axe de la LIO mesuré par photographie au biomicroscope (lampe à fente) dans le cadre d'un examen dilaté.</div></div><div><h3>Résultats</h3><div>L'astigmatisme résiduel mesuré 3 mois après l'intervention (0,81 ± 0,50 D) était plus prononcé que celui qui avait été mesuré 1 semaine après l'intervention (0,41 ± 0,38 D; <em>p</em> < 0,05). La PEI a diminué de 264,44 ± 163,25 μm, et la LIO a subi une rotation de 2,91 ± 1,44 degrés entre la première semaine et le troisième mois après l'intervention (<em>p</em> < 0,05). On a observé une corrélation positive entre la variation de la PEI et la rotation de la LIO (<em>R</em><sup>2</sup> =","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":"60 1","pages":"Pages 8-14"},"PeriodicalIF":3.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141396169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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